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Author: Shinji Doi
Publisher: Springer Science & Business Media
ISBN: 4431538623
Category : Technology & Engineering
Languages : en
Pages : 159
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Book Description
Biological systems inherently possess much ambiguity or uncertainty. Computational electrophysiology is the one area, from among the vast and rapidly growing discipline of computational and systems biology, in which computational or mathematical models have succeeded. This textbook provides a practical and quick guide to both computational electrophysiology and numerical bifurcation analysis. Bifurcation analysis is a very powerful tool for the analysis of such highly nonlinear biological systems. Bifurcation theory provides a way to analyze the effect of a parameter change on a system and to detect a critical parameter value when the qualitative nature of the system changes. Included in this work are many examples of numerical computations of bifurcation analysis of various models as well as mathematical models with different abstraction levels from neuroscience and electrophysiology. This volume will benefit graduate and undergraduate students as well as researchers in diverse fields of science.
Author: Shinji Doi
Publisher: Springer Science & Business Media
ISBN: 4431538623
Category : Technology & Engineering
Languages : en
Pages : 159
Get Book Here
Book Description
Biological systems inherently possess much ambiguity or uncertainty. Computational electrophysiology is the one area, from among the vast and rapidly growing discipline of computational and systems biology, in which computational or mathematical models have succeeded. This textbook provides a practical and quick guide to both computational electrophysiology and numerical bifurcation analysis. Bifurcation analysis is a very powerful tool for the analysis of such highly nonlinear biological systems. Bifurcation theory provides a way to analyze the effect of a parameter change on a system and to detect a critical parameter value when the qualitative nature of the system changes. Included in this work are many examples of numerical computations of bifurcation analysis of various models as well as mathematical models with different abstraction levels from neuroscience and electrophysiology. This volume will benefit graduate and undergraduate students as well as researchers in diverse fields of science.
Author: Matthijs Cluitmans
Publisher: Frontiers Media SA
ISBN: 2832529259
Category : Science
Languages : en
Pages : 229
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Book Description
Author: Karoline Horgmo Jæger
Publisher: Springer Nature
ISBN: 3031308522
Category : Mathematics
Languages : en
Pages : 134
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Book Description
This open access text aims at giving you the simplest possible introduction to differential equations that are used in models of electrophysiology. It covers models at several spatial and temporal scales with associated numerical methods. The text demonstrates that a very limited number of fundamental techniques can be used to define numerical methods for equations ranging from ridiculously simple to extremely complex systems of partial differential equations. Every method is implemented in Matlab and the codes are freely available online. By using these codes, the reader becomes familiar with classical models of electrophysiology, like the cable equation, the monodomain model, and the bidomain model. But modern models that have just started to gain attention in the field of computational electrophysiology are also presented. If you just want to read one book, it should probably not be this one, but if you want a simple introduction to a complex field, it is worth considering the present text.
Author: Frank B. Sachse
Publisher: Springer
ISBN: 3540259260
Category : Medical
Languages : en
Pages : 364
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Book Description
This book is devoted to computer-based modeling in cardiology, by taking an educational point of view, and by summarizing knowledge from several, commonly considered delimited areas of cardiac research in a consistent way. First, the foundations and numerical techniques from mathematics are provided, with a particular focus on the finite element and finite differences methods. Then, the theory of electric fields and continuum mechanics is introduced with respect to numerical calculations in anisotropic biological media. In addition to the presentation of digital image processing techniques, the following chapters deal with particular aspects of cardiac modeling: cardiac anatomy, cardiac electro physiology, cardiac mechanics, modeling of cardiac electro mechanics. This book was written for researchers in modeling and cardiology, for clinical cardiologists, and for advanced students.
Author: Leonardo Franco
Publisher: Springer Nature
ISBN: 3031637720
Category :
Languages : en
Pages : 420
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Book Description
Author: Tommaso Mansi
Publisher: Academic Press
ISBN: 0128168951
Category : Science
Languages : en
Pages : 276
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Book Description
Artificial Intelligence for Computational Modeling of the Heart presents recent research developments towards streamlined and automatic estimation of the digital twin of a patient's heart by combining computational modeling of heart physiology and artificial intelligence. The book first introduces the major aspects of multi-scale modeling of the heart, along with the compromises needed to achieve subject-specific simulations. Reader will then learn how AI technologies can unlock robust estimations of cardiac anatomy, obtain meta-models for real-time biophysical computations, and estimate model parameters from routine clinical data. Concepts are all illustrated through concrete clinical applications. - Presents recent advances in computational modeling of heart function and artificial intelligence technologies for subject-specific applications - Discusses AI-based technologies for robust anatomical modeling from medical images, data-driven reduction of multi-scale cardiac models, and estimations of physiological parameters from clinical data - Illustrates the technology through concrete clinical applications and discusses potential impacts and next steps needed for clinical translation
Author: Jose Jalife
Publisher: Elsevier Health Sciences
ISBN: 0323757464
Category : Medical
Languages : en
Pages : 1709
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Book Description
Fully updated from cover to cover, Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides the comprehensive, multidisciplinary coverage you need—from new knowledge in basic science to the latest clinical advances in the field. Drs. José Jalife and William Gregory Stevenson lead a team of global experts who provide cutting-edge content and step-by-step instructions for all aspects of cardiac electrophysiology. - Packs each chapter with the latest information necessary for optimal basic research as well as patient care. - Covers new technologies such as CRISPR, protein research, improved cardiac imaging, optical mapping, and wearable devices. - Contains significant updates in the areas of molecular biology and genetics, iPSCs (induced pluripotent stem cells), embryonic stem cells, precision medicine, antiarrhythmic drug therapy, cardiac mapping with advanced techniques, and ablation technologies including stereotactic radioablation. - Includes 47 new chapters covering both basic science and clinical topics. - Discusses extensive recent progress in the understanding, diagnosis, and management of arrhythmias, including new clinical insights on atrial fibrillation and stroke prevention, new advances in the understanding of ventricular arrythmias in genetic disease, and advances in implantable devises and infection management. - Features 1,600 high-quality photographs, anatomic and radiographic images, electrocardiograms, tables, algorithms, and more., with additional figures, tables, and videos online. - Recipient of a 2018 Highly Commended award from the British Medical Association. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Author: Oscar Camara
Publisher: Springer
ISBN: 3319287125
Category : Computers
Languages : en
Pages : 229
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Book Description
This book constitutes the thoroughly refereed post-workshop proceedings of the 6th International Workshop on Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges, STACOM 2015, held in conjunction with MICCAI 2015, in Munich, Germany, in October 2015. The 23 revised full workshop papers were carefully reviewed and selected from 34 submissions. The papers cover a wide range of topics such cardiac image processing, atlas construction, statistical modeling of cardiac function across different patient populations, cardiac mapping, cardiac computational physiology, model customization, image-based modelling and image-guided interventional procedures, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analysis.
Author: Esther Puyol Anton
Publisher: Springer Nature
ISBN: 3030681076
Category : Computers
Languages : en
Pages : 427
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Book Description
This book constitutes the proceedings of the 11th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2020, as well as two challenges: M&Ms - The Multi-Centre, Multi-Vendor, Multi-Disease Segmentation Challenge, and EMIDEC - Automatic Evaluation of Myocardial Infarction from Delayed-Enhancement Cardiac MRI Challenge. The 43 full papers included in this volume were carefully reviewed and selected from 70 submissions. They deal with cardiac imaging and image processing, machine learning applied to cardiac imaging and image analysis, atlas construction, artificial intelligence, statistical modelling of cardiac function across different patient populations, cardiac computational physiology, model customization, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analyses, as well as the pre-clinical and clinical applicability of these methods.
Author: Piero Colli Franzone
Publisher: Springer
ISBN: 3319048015
Category : Mathematics
Languages : en
Pages : 410
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Book Description
This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.
