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Author: Nadeem Qureshi
Publisher: DIANE Publishing
ISBN: 1437910998
Category : Health & Fitness
Languages : en
Pages : 201
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Book Description
This systematic review was undertaken to: (1) evaluate the accuracy of patient reporting of cancer family history; (2) identify and evaluate tools designed to capture cancer family history that are applicable to the primary care setting; and (3) identify and evaluate risk assessment tools (RATs) in promoting appropriate management of familial cancer risk in primary care settings. For family history tools (FHxTs) and RATs, studies were limited to those applicable to primary care settings. Conclusions: Informants reporting their cancer family history have greater accuracy for relatives free of cancer than those with cancer. Reporting accuracy may vary among different cancer types. Charts and tables.
Author: Nadeem Qureshi
Publisher: DIANE Publishing
ISBN: 1437910998
Category : Health & Fitness
Languages : en
Pages : 201
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Book Description
This systematic review was undertaken to: (1) evaluate the accuracy of patient reporting of cancer family history; (2) identify and evaluate tools designed to capture cancer family history that are applicable to the primary care setting; and (3) identify and evaluate risk assessment tools (RATs) in promoting appropriate management of familial cancer risk in primary care settings. For family history tools (FHxTs) and RATs, studies were limited to those applicable to primary care settings. Conclusions: Informants reporting their cancer family history have greater accuracy for relatives free of cancer than those with cancer. Reporting accuracy may vary among different cancer types. Charts and tables.
Author: Nadeem Qureshi
Publisher: Department of Health and Human Services Public Health Servic
ISBN: 9781587633294
Category : Cancer
Languages : en
Pages : 84
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Book Description
Author:
Publisher:
ISBN: 9781587633294
Category : Cancer
Languages : en
Pages :
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Book Description
Author: U. S. Department of Health and Human Services
Publisher: Createspace Independent Pub
ISBN: 9781489524478
Category : Medical
Languages : en
Pages : 204
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Book Description
Family history reflects the combined influences of genetics, environmental exposures, and behaviors within families, and is a risk factor for some clinically important chronic diseases such as cardiovascular disease, diabetes mellitus, stroke, and several cancers. Family history reflects genomic, social and environmental risk which is shared between relatives. This 'compressed information' may provide predictive information independent of other known risk factors. Individual risk stratification systems based on family history may carry valuable predictive information for individual patients, but they need to be validated for application in routine practice. The usefulness of family history-based risk stratification systems in disease prevention depends on (a) accurate reporting and capture of family history information, (b) valid methods of risk classification, (c) effective preventive interventions to manage disease risk, and (d) evidence that the use of family history information provides incremental net benefit over and above non-family history-based alternative approaches. With the exception of accuracy of reporting, this systematic review is designed to inform all of these issues. This report, which builds on a previous evidence report on the topic of tools for collecting and interpreting family history information, addresses the clinical utility of routinely using family history information in risk assessment and prevention for breast, ovarian, colorectal, and prostate cancers in primary care. The specific research questions are: 1. Which risk stratification algorithms or guidelines delineate risk accurately, and in a clinically meaningful way? 2. For which behaviors and clinical preventive services ('interventions') is there evidence of benefits in terms of actual reduction in disease risk, and what harms, if any, have been identified? 3. For those interventions identified as being based on reasonable evidence, what is the evidence that providing information on risk status results in behavior change or increased uptake of services on the part of individual patients? 4. What are the harms or risks to individual patients that may result from the collection of family history information in itself, and/or the provision of family history-based risk information? These questions represent the links in the chain between taking family history and producing benefit: Does family history predict future risk of cancer? If so, are there interventions to reduce this risk, and do they also carry their own risks? Does a family history-based approach lead to higher uptake of preventive interventions? Are there any direct harms which arise from a family history-based approach? This review's focus is therefore firmly on the application of family history taking from general populations under the care of primary care providers such as family physicians, internists, nurse practitioners, and obstetricians. We sought to examine the capture and use of family history information as an activity practiced in primary care, where patients are not pre-selected for risk, and where the approach to capturing information is heavily influenced (often constrained) by contextual factors,6 and where the preventive interventions available are those that can be recommended by a primary care practitioner. This is distinctly different from clinical genetics assessment, where the central focus is on extensive family history capture, validation, and assessment, where the patient population is usually pre-selected for high risk status.
Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 199
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Book Description
Author: Agency for Healthcare Research and Quality/AHRQ
Publisher: Government Printing Office
ISBN: 1587634333
Category : Medical
Languages : en
Pages : 396
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Book Description
This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.
Author: Nathaniel H. Robin
Publisher: Elsevier Health Sciences
ISBN: 0323495966
Category : Medical
Languages : en
Pages : 350
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Book Description
Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.
Author: Kathy Steligo
Publisher: JHU Press
ISBN: 1421444275
Category : Health & Fitness
Languages : en
Pages : 496
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Book Description
The most comprehensive guide available on hereditary cancers, from understanding risk, prevention, and genetic counseling and testing to treatment, quality of life, and more. Up to 10 percent of cancers are caused by inherited mutations in specific genes. Finding out that you or your loved ones may be at increased risk of developing cancer because of a genetic mutation raises a lot of questions: Is cancer inevitable? Is there anything I should do differently in my life? Will my children also be at higher risk of cancer? Should I have preemptive treatments or surgery? This comprehensive guide provides answers to these questions and more. Written by three passionate patient advocates, this book is a compilation of the trusted information and support provided for more than two decades by Facing Our Risk of Cancer Empowered (FORCE), the de facto voice of the hereditary cancer community. Combining the latest scientific research with national guidelines, expert advice, and compelling patient stories, the book offers previvors (those who have a mutation but have never been diagnosed), survivors, and their families the guidance they need to face the unique physical and emotional challenges of living in a high-risk body. An ideal resource for genetic counselors, physicians, nurses, advocates, and others who support and care for the hereditary cancer community, Living with Hereditary Cancer Risk also provides coverage of • signs of inherited cancer risk in a family; • the value of genetic counseling and testing; • mutations in BRCA, Lynch Syndrome, and other genes that elevate cancer risk; • risk-reducing strategies; • traditional treatments and newer personalized approaches, including immunotherapies and PARP inhibitors; • nationally recommended guidelines for prevention, early detection, and treatment; • insurance coverage and discrimination protections; and • coping with sexual health, fertility, menopause, and other quality of life issues.
Author: Mack T. Ruffin IV
Publisher: Elsevier Health Sciences
ISBN: 0323299482
Category : Medical
Languages : en
Pages : 237
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Book Description
This issue of Primary Care: Clinics in Office Practice, edited by Mack T. Ruffin IV, MD, MPH and Cameron G. Shultz PhD, MSW, is devoted to Preventive Medicine. Articles in this issue include Risk Assessment Approach Screening; Substance Use and Tobacco Screening; Sexually Transmitted Infections; Planned Pregnancy; Violence Screening; Breast Cancer Screening; Lung Cancer Screening; Colorectal Cancer Screening; Prostate Cancer Screening; Heart Disease Screening; Screening for Depression; and Use of Genetic Markers.
Author: Robin L. Bennett
Publisher: John Wiley & Sons
ISBN: 0471459143
Category : Medical
Languages : en
Pages : 271
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Book Description
The Practical Guide to The Genetic Family History Robin L. Bennett Compiling the most recent genetic developments in medical specialties, The Practical Guide to the Genetic Family History is a valuable resource which outlines the proper methods for taking and recording a patient's family medical history, allowing primary care physicians to be more efficient in diagnosing conditions with potential genetic components. With genetic screening forms, an overview of directed questions, pedigree nomenclature, and outlining common approaches used, genetic counselor Robin L. Bennett provides readers with the basic foundation in human genetics necessary to recognize inherited disorders and familial disease susceptibility in patients. As the only guide which is geared for the physician in this field, The Practical Guide to the Genetic Family History includes remarks by renowned medical geneticist Arno Motulsky, as well as information on structuring an accurate pedigree and its components, including: * Using a pedigree to identify individuals with an increased susceptibility to cancer * Family history, adoption, and their challenges * The connection between the pedigree and assisted reproductive technologies * Making referrals for genetic services * Neurological and neuromuscular conditions * Tables covering hearing loss, mental retardation, dementia, and seizures * Five case studies of genetics in practice An essential reference for genetics clinics, medical geneticists, and counselors, The Practical Guide to the Genetic Family History is also an invaluable aid for both primary care and specialist physicians who need an up-to-date reference that emphasizes both the science and art of modern clinical genetics.
