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Author: Martin Scholz
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805566026
Category : Medical
Languages : en
Pages : 321
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Book Description
'This monograph will appeal to clinical microbiologists, and virologists involved in the care of transplant recipients and AIDS patients, as it provides the scientific basis of antiviral drug activity, molecular diagnosis and also of possible immunopathogenic mechanisms of CMV disease and CMV-related graft rejection.... it is highly recommended.'
Author: Martin Scholz
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805566026
Category : Medical
Languages : en
Pages : 321
Get Book Here
Book Description
'This monograph will appeal to clinical microbiologists, and virologists involved in the care of transplant recipients and AIDS patients, as it provides the scientific basis of antiviral drug activity, molecular diagnosis and also of possible immunopathogenic mechanisms of CMV disease and CMV-related graft rejection.... it is highly recommended.'
Author: M. Scholz
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318002623
Category : Medical
Languages : en
Pages : 321
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Book Description
Cytomegalovirus (CMV) infection can cause severe diseases with significant morbidity and mortality in immunocompromised patients such as bone marrow or solid-organ transplant recipients, and AIDS patients. Major manifestations include transplant rejection, hepatitis, pneumonitis, encephalitis and retinitis. There is growing evidence that in certain cases CMV disease is closely linked to aberrant immune responses occurring locally within the respective tissues. This book provides important new insights into CMV-related immunopathology, discusses current methods of CMV diagnosis and anti-CMV therapy, and proposes novel antiviral treatment strategies. It contains contributions by leading scientists and clinicians in the field of CMV, who participated in the 'First International Round Table Consensus Meeting', held in Frankfurt, Germany, in August 1997. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working on herpesvirus biology and the development of antiviral drugs.
Author: Susanna Prösch
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805576188
Category : Medical
Languages : en
Pages : 222
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Book Description
Cytomegalovirus (CMV) infection causes severe diseases in immunocompromised patients. CMV-related morbidity is frequently linked to aberrant immune responses occurring locally within the respective tissues including immune-privileged sites such as the retina. There is growing evidence that CMV-related pathomechanisms differ profoundly as a function of cell type and differentiation state of the host cell. This book provides important new insights into CMV-related immunopathology, discusses molecular mechanisms involved in HCMV-mediated tissue injury, CMV latency and reactivation, and presents novel ideas and concepts to develop alternative antiviral drugs. As an important focus, the role of CMV-reactive T cells in protection, pathogenesis, diagnosis and therapy of HCMV infection is discussed. The contributions to this book are written by leading scientists and clinicians in the field of CMV who participated in the fourth international meeting on CMV-related immunopathology, held in Berlin, September 2002. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working in the field of herpesvirus biology and the development of antiviral drugs.
Author: S. Prösch
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318010065
Category : Medical
Languages : en
Pages : 222
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Book Description
Cytomegalovirus (CMV) infection causes severe diseases in immunocompromised patients. CMV-related morbidity is frequently linked to aberrant immune responses occurring locally within the respective tissues including immune-privileged sites such as the retina. There is growing evidence that CMV-related pathomechanisms differ profoundly as a function of cell type and differentiation state of the host cell. This book provides important new insights into CMV-related immunopathology, discusses molecular mechanisms involved in HCMV-mediated tissue injury, CMV latency and reactivation, and presents novel ideas and concepts to develop alternative antiviral drugs. As an important focus, the role of CMV-reactive T cells in protection, pathogenesis, diagnosis and therapy of HCMV infection is discussed. The contributions to this book are written by leading scientists and clinicians in the field of CMV who participated in the fourth international meeting on CMV-related immunopathology, held in Berlin, September 2002. Comprehensive and up-to-date, this volume is a vital reference for clinicians involved in the diagnosis and treatment of CMV infections, as well as for researchers working in the field of herpesvirus biology and the development of antiviral drugs.
Author: Thomas E. Shenk
Publisher: Springer Science & Business Media
ISBN: 3540773495
Category : Medical
Languages : en
Pages : 477
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Book Description
This volume has gathered some of the experts in the field to review aspects of our understanding of CMV and to offer perspectives of the current problems associated with CMV. The editors and authors hope that the chapters will lead to a better understanding of the virus that will assist in the development of new and unique antivirals, a protective vaccine, and a full understanding of CMV's involvement in human disease.
Author: Victor Kuete
Publisher: Academic Press
ISBN: 0128094419
Category : Medical
Languages : en
Pages : 692
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Book Description
Medicinal Spices and Vegetables from Africa: Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases provides a detailed look at medicinal spices and vegetables that have proven safe-and-effective for consumption and the treatment of diseases, including infectious diseases, cardiovascular disease, and cancer. It provides pharmacological evidence, such as the latest information related to efficacy and safety data, in vitro and in vivo studies, clinical trials, and more, to illustrate the use of these spices and vegetables as both palliative and alternative treatments with the goal of furthering research in this area to produce safer and more effective drugs. - Provides scientific evidence for the potential of medicinal spices and vegetables used in Africa to fight metabolic, inflammatory, and infectious diseases - Includes a review of the latest methods used to investigate the effects of medicinal plants in the treatment of disease - Offers an updated resource for students sand scientists in the fields of pharmaceutical science, pharmacognosy, complementary and alternative medicine, ethnopharmacology, phytochemistry, biochemistry, and more
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309220394
Category : Science
Languages : en
Pages : 200
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Book Description
For many years, experiments using chimpanzees have been instrumental in advancing scientific knowledge and have led to new medicines to prevent life-threatening and debilitating diseases. However, recent advances in alternate research tools have rendered chimpanzees largely unnecessary as research subjects. The Institute of Medicine, in collaboration with the National Research Council, conducted an in-depth analysis of the scientific necessity for chimpanzees in NIH-funded biomedical and behavioral research. The committee concludes that while the chimpanzee has been a valuable animal model in the past, most current biomedical research use of chimpanzees is not necessary, though noted that it is impossible to predict whether research on emerging or new diseases may necessitate chimpanzees in the future.
Author: Krassimir Metodiev
Publisher: BoD – Books on Demand
ISBN: 953512210X
Category : Medical
Languages : en
Pages : 314
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Book Description
This book is a continuation of the efforts of InTech to expand the scientific know-how in the field of immunopathology and bring valuable updated information to medical professionals and researchers. It consists of chapters related to various approaches to investigate the unique role of the immune system in response to different clinical disorders. The international team of authors is the bonus of the book, reflecting the rapid development of immunology and new achievements in medical science. We firmly hope that the book will be an excellent manual and guideline for people dealing with biology, microbiology, immunology, virology, pharmacology, general and dental medicine, and health care, from students and postdocs to high-level specialists and university professors.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309174988
Category : Medical
Languages : en
Pages : 472
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Book Description
Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.
Author:
Publisher: Elsevier
ISBN: 0080532403
Category : Science
Languages : en
Pages : 297
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Book Description
Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences.Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas.The recent development of Gene Therapy procedures which allow specific genes to be delivered to human patients who lack functional copies of them is of major therapeutic importance. In addition such gene delivery methods can be used in other organisms to define the function of particular genes. These studies are of particular interest in the nervous system where there are many incurable diseases like Alzheimer's and Parkinson's diseases which may benefit from therapies of this kind. Unfortunately gene delivery methods for use in the nervous system have lagged behind those in other systems due to the fact that the methods developed in other systems are often not applicable to cells like neurons which do not divide. This book discusses a wide range of methods which have now been developed to overcome these problems and allow safe and efficient delivery of particular genes to the brain. Methods discussed include virological methods, physical methods (such as liposomes) and the transplantation of genetically modified cells. In a single volume therefore this book provides a complete view of these methods and indicates how they can be applied to the development of therapies for treating previously incurable neurological disorders.
