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Author: Sergej M. Ostojic
Publisher: Academic Press
ISBN: 0128227729
Category : Science
Languages : en
Pages : 720
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Book Description
Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics, as well as the safety and efficacy of emerging management strategies to address poor cellular bioenergetics. Topics discussed include the omics landscape of impaired mitochondrial bioenergetics, hormones, tissue bioenergetics and metabolism in humans. Disease-specific case studies, modes of analysis in clinical bioenergetics, and therapeutic opportunities for impaired bioenergetics, addressing both known treatment pathways and future directions for research, are discussed in-depth. Diseases and Disorders examined include brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among others. - Provides a thorough discussion of foundational aspects of bioenergetics and disease, modes of analysis, and treatments for impaired bioenergetics - Discusses the role of bioenergetics and treatment pathways in brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among other diseases and disorders - Features chapter contributions from international leaders in translational bioenergetics research and clinical practice
Author: Sergej M. Ostojic
Publisher: Academic Press
ISBN: 0128227729
Category : Science
Languages : en
Pages : 720
Get Book Here
Book Description
Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics, as well as the safety and efficacy of emerging management strategies to address poor cellular bioenergetics. Topics discussed include the omics landscape of impaired mitochondrial bioenergetics, hormones, tissue bioenergetics and metabolism in humans. Disease-specific case studies, modes of analysis in clinical bioenergetics, and therapeutic opportunities for impaired bioenergetics, addressing both known treatment pathways and future directions for research, are discussed in-depth. Diseases and Disorders examined include brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among others. - Provides a thorough discussion of foundational aspects of bioenergetics and disease, modes of analysis, and treatments for impaired bioenergetics - Discusses the role of bioenergetics and treatment pathways in brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among other diseases and disorders - Features chapter contributions from international leaders in translational bioenergetics research and clinical practice
Author: David G. Nicholls
Publisher: Academic Press
ISBN: 0123884314
Category : Science
Languages : en
Pages : 434
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Book Description
Extensively revised, the fourth edition of this highly successful book takes into account the many newly determined protein structures that provide molecular insight into chemiosmotic energy transduction, as well as reviewing the explosive advances in 'mitochondrial physiology'-the role of the mitochondria in the life and death of the cell. Covering mitochondria, bacteria and chloroplasts, the fourth edition of Bioenergetics provides a clear and comprehensive account of the chemiosmotic theory and its many applications. The figures have been carefully designed to be memorable and to convey the key functional and mechanistic information. Written for students and researchers alike, Bioenergetics is the most well-known, current and respected text on chemiosmotic theory and membrane bioenergetics available. - BMA Medical Book Awards 2014-Highly Commended, Basic and Clinical Sciences,2014,British Medical Association - Chapters are now divided between three interlocking sections: basic principles, structures and mechanisms, and mitochondrial physiology - Covers new advances in the structure and mechanism of key bioenergetic proteins, including complex I of the respiratory chain and transport proteins - Details cellular bioenergetics, mitochondrial cell biology and signal transduction, and the roles of mitochondria in physiology, disease and aging - Offers readers clear, visual representation of structural concepts through full colour figures throughout the book
Author: Vladimir P. Skulachev
Publisher: Springer Science & Business Media
ISBN: 364233430X
Category : Science
Languages : en
Pages : 435
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Book Description
Principles of Bioenergetics summarizes one of the quickly growing branches of modern biochemistry. Bioenergetics concerns energy transductions occurring in living systems and this book pays special attention to molecular mechanisms of these processes. The main subject of the book is the "energy coupling membrane" which refers to inner membranes of intracellular organelles, for example, mitochondria and chloroplasts. Cellular cytoplasmic membranes where respiratory and photosynthetic energy transducers, as well as ion-transporting ATP-synthases (ATPases) are also part of this membrane. Significant attention is paid to the alternative function of mitochondria as generators of reactive oxygen species (ROS) that mediate programmed death of cells (apoptosis and necrosis) and organisms (phenoptosis). The latter process is considered as a key mechanism of aging which may be suppressed by mitochondria-targeted antioxidants.
Author: Jie Kang
Publisher: Human Kinetics
ISBN: 9780736062411
Category : Medical
Languages : en
Pages : 232
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Book Description
"More in-depth than cursory discussions found in exercise physiology texts and more practical and accessible than dedicated bioenergetics texts, Bioenergetics Primer for Exercise Science encompasses all the up-to-date research and information regarding human bioenergetics and energy metabolism. It offers both students and professionals a depth of knowledge that will inform their further study, research, and profession."--Jacket.
Author:
Publisher: Academic Press
ISBN: 0128201266
Category : Medical
Languages : en
Pages : 458
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Book Description
Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease summarizes recent developments in intervention trials in neurodegenerative diseases, particularly Alzheimer's and Parkinson's, as well as increasing evidence for the overlap between drivers of metabolic and neurodegenerative disease that impact mitochondrial function and bioenergetics, and subsequently cellular function and pathophysiology. Topics covered include Brain Glucose and Ketone Utilization in Brain Ageing and Neurodegenerative Diseases; the Mitochondrial Hypothesis: Dysfunction, Bioenergetic Defects, and the Metabolic Link to Alzheimer's Disease; the Metabolic Impact on Neuroinflammation and Microglial Modulation in Neurodegenerative Diseases, the Impact of Circadian and Diurnal Rhythms on Cellular Metabolic Function and Neurodegenerative Diseases, and much more. - Summarizes the current status of and future research in Alzheimer's and Parkinson's diseases - Reviews the impact of the metabolic hypothesis on underlying mechanisms of neurodegenerative diseases
Author: George Austin Brooks
Publisher: McGraw-Hill Humanities, Social Sciences & World Languages
ISBN:
Category : Medical
Languages : en
Pages : 778
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Book Description
Author: E. Carafoli
Publisher: Springer Science & Business Media
ISBN: 3642675301
Category : Science
Languages : en
Pages : 187
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Book Description
This manual collects in the form of laboratory protocols a series of experiments in the field of Membrane Transport and Membrane Bioenergetics. It represents the experience accumulated during four advanced courses held at the Depart ment of Biochemistry of the Swiss Federal Institute of Technology on behalf of Federation of European Biochemical Societies (FEBS) in the years 1975 through 1978. The idea of collecting the experiments into a laboratory manual developed as a response to a demand from the students who took part in the courses. Further motivation came with the fmding that, in planning the laboratory sessions, the teaching staff had no organized, modern source of information in the literature. The experiments presented cover most areas of importance in the subject mat ter. Their presentation has been continuously modified in the course of the four years during which the manual took shape, to accommodate to experience and various suggestions. In their present form, all of the experiments described have been repeatedly practiced to optimize their execution. Efforts have been made to combine in the manual classical experiments, and techniques which require relatively unsophisticated instrumentation and can therefore be carried out in most laboratories, with more modern experiments and relatively newer technol ogies. In its present form, the manual should therefore provide a usefui tool in the hands of researchers and laboratory teachers at different levels of sophisti cation and instrumentation.
Author: Jeffrey W. Berkin
Publisher:
ISBN: 9781617617881
Category : Bioenergetics
Languages : en
Pages : 0
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Book Description
Bioenergetics is the subject of a field of biochemistry that concerns energy flow through living systems. This is an active area of biological research that includes the study of thousands of different cellular processes such as cellular respiration and the many other metabolic processes that can lead to production and utilisation of energy in forms such as ATP molecules. This book presents current research from across the globe in the study of bioenergetics, including Cell ATP production by mitochondria; bioenergetics of closed ecological systems; bioenergetics of thermus thermophilus; as well as screening and studying photosynthetic mutants.
Author: S. Papa
Publisher: Springer Science & Business Media
ISBN: 1461548438
Category : Science
Languages : en
Pages : 827
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Book Description
1. The Mitochondrial and Bacterial Respiratory Chains: From MacMunn and Keilin to Current Concepts; P. Nicholls. 2. The Mitochondrial Enzymes of Oxidative Phosphorylation; Y. Hatefi. 3. Proton Pumps of Respiratory Chain Enzymes; S. Papa, et al. 4. Uncoupling of Respiration and Phosphorylation; V.P. Skulachev. 5. Crystallization, Structure, and Possible Mechanism of Action of Cytochrome c Oxidase from the Soil Bacterium Paracoccus denitrificans; M. Hartmut, et al. 6. The Structure of Crystalline Bovine Heart Cytochrome c Oxidase; S. Yoshikawa, et al. 7. Electron and Proton Transfer in.
Author: Helmut W. Schimmel
Publisher: Thieme
ISBN: 9783830407393
Category : Medical
Languages : en
Pages : 414
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Book Description
This is the updated English edition of the first volume of the acclaimed textbook by the leading German proponent of bioenergetic medicine who is also the founder of the VEGATEST-Method. Functional Medicine provides the foundation for understanding and using bioenergetics. It is grounded in both Oriental and Occidental medical knowledge and deals with the bioenergetic events which precede and accompany biochemical and organic pathology. Functional Medicine embraces the totality of regulatory functions of the organism and employs energy-oriented diagnostic methods to reveal the energetic events leading to an advanced diagnosis. The findings can then be utilized for the prevention of a disease, or in the face of the fully developed disease, they can provide the proper therapeutic guidance. The practice of functional medicine demands a thorough knowledge of clinical medicine, heteropathic, linked with a holistic attitude and a familiarity with the principles of acupuncture. It also requires a working understanding of stomatology, otorhinolaryngology and neurology. Necessary as well is manual dexterity and skill in the use of bioelectronic instrumentation. Although current conventional medicine saves lives in major acute infections and injuries, it offers very little to those with chronic disease. Functional Medicine offers a meaningful complement to clinical medicine and closes existing gaps in diagnosis and therapies.
