Clinical Applications of Physiome Models

Clinical Applications of Physiome Models PDF Author: Eun Bo Shim
Publisher: Frontiers Media SA
ISBN: 2889639193
Category :
Languages : en
Pages : 150

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Book Description

Clinical Applications of Physiome Models

Clinical Applications of Physiome Models PDF Author: Eun Bo Shim
Publisher: Frontiers Media SA
ISBN: 2889639193
Category :
Languages : en
Pages : 150

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Book Description


Repair and Redesign of Physiological Systems

Repair and Redesign of Physiological Systems PDF Author: Mark A. Atherton
Publisher: WIT Press
ISBN: 1845640969
Category : Science
Languages : en
Pages : 305

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Book Description
In this volume the author highlights the role of engineering and relevant mathematics in medicine. Like engineering systems, human physiology can wear out or fail to an extent where it requires a clinical interventionist to repair or even redesign the system. There is a long tradition amongst clinicians of working with engineers and mathematicians, and this volume continues the theme with modern developments. Hence chapters deal with vascular surgery planning, cardiac and vascular devices, immunotherapeutics, plus nasal and dental repair. More generically, some of these chapters relate to preserving the integrity of the human 'surface structure', as well as the challenges in computer modeling the complexities and multiscale nature of the human physiome.

Handbook of Digital Human Modeling

Handbook of Digital Human Modeling PDF Author: Vincent G. Duffy
Publisher: CRC Press
ISBN: 1420063529
Category : Computers
Languages : en
Pages : 1034

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Book Description
The rapid introduction of sophisticated computers, services, telecommunications systems, and manufacturing systems has caused a major shift in the way people use and work with technology. It is not surprising that computer-aided modeling has emerged as a promising method for ensuring products meet the requirements of the consumer. The Handbook of D

Systems Medicine

Systems Medicine PDF Author:
Publisher: Academic Press
ISBN: 0128160780
Category : Science
Languages : en
Pages : 1571

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Book Description
Technological advances in generated molecular and cell biological data are transforming biomedical research. Sequencing, multi-omics and imaging technologies are likely to have deep impact on the future of medical practice. In parallel to technological developments, methodologies to gather, integrate, visualize and analyze heterogeneous and large-scale data sets are needed to develop new approaches for diagnosis, prognosis and therapy. Systems Medicine: Integrative, Qualitative and Computational Approaches is an innovative, interdisciplinary and integrative approach that extends the concept of systems biology and the unprecedented insights that computational methods and mathematical modeling offer of the interactions and network behavior of complex biological systems, to novel clinically relevant applications for the design of more successful prognostic, diagnostic and therapeutic approaches. This 3 volume work features 132 entries from renowned experts in the fields and covers the tools, methods, algorithms and data analysis workflows used for integrating and analyzing multi-dimensional data routinely generated in clinical settings with the aim of providing medical practitioners with robust clinical decision support systems. Importantly the work delves into the applications of systems medicine in areas such as tumor systems biology, metabolic and cardiovascular diseases as well as immunology and infectious diseases amongst others. This is a fundamental resource for biomedical students and researchers as well as medical practitioners who need to need to adopt advances in computational tools and methods into the clinical practice. Encyclopedic coverage: ‘one-stop’ resource for access to information written by world-leading scholars in the field of Systems Biology and Systems Medicine, with easy cross-referencing of related articles to promote understanding and further research Authoritative: the whole work is authored and edited by recognized experts in the field, with a range of different expertise, ensuring a high quality standard Digitally innovative: Hyperlinked references and further readings, cross-references and diagrams/images will allow readers to easily navigate a wealth of information

Modeling of Physiological Flows

Modeling of Physiological Flows PDF Author: Davide Ambrosi
Publisher: Springer Science & Business Media
ISBN: 8847019354
Category : Mathematics
Languages : en
Pages : 418

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Book Description
This book offers a mathematical update of the state of the art of the research in the field of mathematical and numerical models of the circulatory system. It is structured into different chapters, written by outstanding experts in the field. Many fundamental issues are considered, such as: the mathematical representation of vascular geometries extracted from medical images, modelling blood rheology and the complex multilayer structure of the vascular tissue, and its possible pathologies, the mechanical and chemical interaction between blood and vascular walls, and the different scales coupling local and systemic dynamics. All of these topics introduce challenging mathematical and numerical problems, demanding for advanced analysis and efficient simulation techniques, and pay constant attention to applications of relevant clinical interest. This book is addressed to graduate students and researchers in the field of bioengineering, applied mathematics and medicine, wishing to engage themselves in the fascinating task of modeling the cardiovascular system or, more broadly, physiological flows.

Biomedical Simulation

Biomedical Simulation PDF Author: Fernando Bello
Publisher: Springer
ISBN: 3319120573
Category : Computers
Languages : en
Pages : 255

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Book Description
This book constitutes the thoroughly refereed conference proceedings of the 6th International Symposium on Biomedical Simulation (ISBMS) which was held in Strasbourg, France, in October 2014. Biomedical modeling and simulation are at the center stage of worldwide efforts to understand and replicate the behavior and function of the human organism. Large scale initiatives such as the Physiome Project, Virtual Physiological Human and Blue Brain Project aim to develop advanced computational models that will facilitate the understanding of the integrative function of cells, organs, and organisms, with the ultimate goal of delivering truly personalized medicine. At the same time, progress in modeling, numerical techniques and haptics has enabled more complex and interactive simulations. The 27 revised full papers (including 16 regular and 11 short papers) were carefully selected from 45 submissions and cover topics such as training systems and haptics, physics-based registration, vascular modeling and simulation, image and simulation, modeling, surgical planning, analysis, characterization and validation.

The Digital Patient

The Digital Patient PDF Author: C. D. Combs
Publisher: John Wiley & Sons
ISBN: 1118952766
Category : Mathematics
Languages : en
Pages : 389

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Book Description
A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.

Developing the Digital Lung, E-Book

Developing the Digital Lung, E-Book PDF Author: John D. Newell
Publisher: Elsevier Health Sciences
ISBN: 0323795021
Category : Medical
Languages : en
Pages : 162

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Book Description
Reflecting recent major advances in the field of artificial intelligence, Developing the Digital Lung, From First Lung CT to Clinical AI, by Dr. John Newell, is your go-to reference for all aspects of applied artificial intelligence in lung disease development, including application to clinical medicine. It provides a unique overview of the field, beginning with a review of the origins of artificial intelligence in the mid-1970s and progressing to its application to clinical medicine in the early 2020s. Organized based on the four stages of development, this practical, easy-to-use resource helps you effectively apply artificial intelligences to lung imaging. - Traces the development of precise quantitative CT of diffuse lung disease through the use of applied AI, leading to faster effective diagnosis of patients with lung disease. - Reviews CT manufacturers, models and scanning protocol used to produce the 3D digital maps of the lungs. - Discusses how the data processed by AI algorithms can produce measures of emphysema, air trapping, and airway wall thickening in subjects with COPD and measures of pulmonary fibrosis and traction bronchiectasis in idiopathic pulmonary fibrosis (IPF). - Demonstrates the differences between reactive machine AI and limited memory AI methods. - Includes comprehensive case studies and current information on cloud computing.

Principles of Genetics and Molecular Epidemiology

Principles of Genetics and Molecular Epidemiology PDF Author: Juan Carlos Gomez-Verjan
Publisher: Springer Nature
ISBN: 3030896013
Category : Science
Languages : en
Pages : 214

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Book Description
This book covers some of the most novel genetic and genomic concepts in epidemiology, such as geospatial statistics and systems biology from a clinical point of view by explaining molecular applications with accessible human studies. Featuring a comprehensive table of contents, it includes chapters from genomics and epidemiology surveillance to transcriptomics and alternative splicing principles. Across 17 well-organized chapters, this book meets attempt to explain easily to clinicians and students with basic principles of the genetics, genomics, molecular biology and its applications to epidemiology and public health. The text is distinct from other literature on the market because it covers useful genomic tools applied in epidemiology for clinicians who may not be experts in this branch of health science. Principles of Genetics and Molecular Epidemiology demystifies the idea that biomedicine is far from being applied in both epidemiology and clinical practice.

Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007

Medical Image Computing and Computer-Assisted Intervention – MICCAI 2007 PDF Author: Nicholas Ayache
Publisher: Springer
ISBN: 3540757570
Category : Computers
Languages : en
Pages : 1044

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Book Description
This title is part of a two-volume set that constitute the refereed proceedings of the 10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007. Coverage in this first volume includes diffusion tensor imaging and computing, cardiac imaging and robotics, image segmentation and classification, image guided intervention and robotics, innovative clinical and biological applications, brain atlas computing, and simulation of therapy.