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Author: Robert M. Strieter
Publisher: CRC Press
ISBN: 0824747445
Category : Medical
Languages : en
Pages : 367
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Book Description
This reference discusses the role of chemokines in mediating leukocyte trafficking, angiogenesis, tumor cell metastasis, host defense, trauma-induced lung injury, and the progression of AIDS in the lung, and studies cytokines as natural agents for modulating diseases that affect the lung.
Author: Robert M. Strieter
Publisher: CRC Press
ISBN: 0824747445
Category : Medical
Languages : en
Pages : 367
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Book Description
This reference discusses the role of chemokines in mediating leukocyte trafficking, angiogenesis, tumor cell metastasis, host defense, trauma-induced lung injury, and the progression of AIDS in the lung, and studies cytokines as natural agents for modulating diseases that affect the lung.
Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728
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Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: Jeffrey K. Harrison
Publisher: Springer Science & Business Media
ISBN: 1597450200
Category : Medical
Languages : en
Pages : 412
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Book Description
This volume, new to The Receptors series, focuses on several areas, including the birth, maturation, and structure of Chemokines; Neutrophil, Dendritic, and Lymphocyte trafficking; and Chemokine Receptors in diseases such as AIDs and lung cancer. In particular the book contains cutting-edge information ranging from basic molecular and cellular mechanisms to physiological and pathological roles of chemokines.
Author: Eckhard Kownatzki
Publisher: Nelson Thornes
ISBN: 9783764358181
Category : Medical
Languages : en
Pages : 160
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Book Description
Chemokines: Attraction of dendritic cells and role in tumor immunobiology.- Chemokine receptors.- Regulation of gene expression of chemokines and their receptors.- Chemokines and T lymphocytes.- Chemokines and mast cells.- Chemokines and eosinophils.- CXC-chemokines - autocrine growth factors for melanoma and epidermoid carcinoma cells.- Expression of chemokines in dermatoses.
Author: Kamal Dua
Publisher: Springer Nature
ISBN: 9813368276
Category : Medical
Languages : en
Pages : 926
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Book Description
The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.
Author: Dorothee Heemskerk
Publisher: Springer
ISBN: 3319191322
Category : Medical
Languages : en
Pages : 71
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Book Description
This work contains updated and clinically relevant information about tuberculosis. It is aimed at providing a succinct overview of history and disease epidemiology, clinical presentation and the most recent scientific developments in the field of tuberculosis research, with an emphasis on diagnosis and treatment. It may serve as a practical resource for students, clinicians and researchers who work in the field of infectious diseases.
Author: Klaus Ley
Publisher: Frontiers Media SA
ISBN: 2889194302
Category : Chemokines
Languages : en
Pages : 109
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Book Description
Arrest chemokines are a small group of chemokines that promote leukocyte arrest from rolling by triggering rapid integrin activation. Arrest chemokines have been described for neutrophils, monocytes, eosinophils, naïve lymphocytes and effector memory T cells. Most arrest chemokines are immobilized on the endothelial surface by binding to heparin sulfate proteoglycans. Whether soluble chemokines can promote integrin activation and arrest is controversial (Alon-Gerszten). Many aspects of the signaling pathway from the GPCR chemokine receptor to integrin activation are the subject of active investigation. Leukocyte adhesion deficiency III is a human disease in which chemokine-triggered integrin activation is defective because of a mutation in the cytoskeletal protein kindlin-3. About 10 different such mutations have been described. The defects seen in patients with LAD-III elucidate the importance of rapid integrin activation for host defense in humans. We welcome reports that help clarifying this crucial first step in the process of leukocyte transendothelial migration.
Author: Leonard Weiss
Publisher: Macmillan Reference USA
ISBN:
Category : Medical
Languages : en
Pages : 362
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Book Description
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Victor R. Preedy
Publisher: Springer
ISBN: 9789400776951
Category : Medical
Languages : en
Pages : 0
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Book Description
In the past decade there has been a major sea change in the way disease is diagnosed and investigated due to the advent of high throughput technologies, such as microarrays, lab on a chip, proteomics, genomics, lipomics, metabolomics etc. These advances have enabled the discovery of new and novel markers of disease relating to autoimmune disorders, cancers, endocrine diseases, genetic disorders, sensory damage, intestinal diseases etc. In many instances these developments have gone hand in hand with the discovery of biomarkers elucidated via traditional or conventional methods, such as histopathology or clinical biochemistry. Together with microprocessor-based data analysis, advanced statistics and bioinformatics these markers have been used to identify individuals with active disease or pathology as well as those who are refractory or have distinguishing pathologies. New analytical methods that have been used to identify markers of disease and is suggested that there may be as many as 40 different platforms. Unfortunately techniques and methods have not been readily transferable to other disease states and sometimes diagnosis still relies on single analytes rather than a cohort of markers. There is thus a demand for a comprehensive and focused evidenced-based text and scientific literature that addresses these issues. Hence the formulation of Biomarkers in Disease. The series covers a wide number of areas including for example, nutrition, cancer, endocrinology, cardiology, addictions, immunology, birth defects, genetics and so on. The chapters are written by national or international experts and specialists.
