Toxicity Testing in the 21st Century

Toxicity Testing in the 21st Century PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309109922
Category : Nature
Languages : en
Pages : 217

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Book Description
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.

Toxicity Testing in the 21st Century

Toxicity Testing in the 21st Century PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309109922
Category : Nature
Languages : en
Pages : 217

Get Book Here

Book Description
Advances in molecular biology and toxicology are paving the way for major improvements in the evaluation of the hazards posed by the large number of chemicals found at low levels in the environment. The National Research Council was asked by the U.S. Environmental Protection Agency to review the state of the science and create a far-reaching vision for the future of toxicity testing. The book finds that developing, improving, and validating new laboratory tools based on recent scientific advances could significantly improve our ability to understand the hazards and risks posed by chemicals. This new knowledge would lead to much more informed environmental regulations and dramatically reduce the need for animal testing because the new tests would be based on human cells and cell components. Substantial scientific efforts and resources will be required to leverage these new technologies to realize the vision, but the result will be a more efficient, informative and less costly system for assessing the hazards posed by industrial chemicals and pesticides.

Chemical Testing Using New Approach Methodologies (NAMs)

Chemical Testing Using New Approach Methodologies (NAMs) PDF Author: Amy J. Clippinger
Publisher: Frontiers Media SA
ISBN: 2832508596
Category : Science
Languages : en
Pages : 139

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Book Description


Alternative Toxicological Methods

Alternative Toxicological Methods PDF Author: Harry Salem
Publisher: CRC Press
ISBN: 0203008790
Category : Medical
Languages : en
Pages : 618

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Book Description
Bringing together the recent and relevant contributions of over 125 scientists from industry, government, and academia in North America and Western Europe, Alternative Toxicological Methods explores the development and validation of replacement, reduction, and refinement alternatives (the 3Rs) to animal testing. Internationally recognized scientist

Exposure Science in the 21st Century

Exposure Science in the 21st Century PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309264685
Category : Nature
Languages : en
Pages : 210

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Book Description
From the use of personal products to our consumption of food, water, and air, people are exposed to a wide array of agents each day-many with the potential to affect health. Exposure Science in the 21st Century: A Vision and A Strategy investigates the contact of humans or other organisms with those agents (that is, chemical, physical, and biologic stressors) and their fate in living systems. The concept of exposure science has been instrumental in helping us understand how stressors affect human and ecosystem health, and in efforts to prevent or reduce contact with harmful stressors. In this way exposure science has played an integral role in many areas of environmental health, and can help meet growing needs in environmental regulation, urban and ecosystem planning, and disaster management. Exposure Science in the 21st Century: A Vision and A Strategy explains that there are increasing demands for exposure science information, for example to meet needs for data on the thousands of chemicals introduced into the market each year, and to better understand the health effects of prolonged low-level exposure to stressors. Recent advances in tools and technologies-including sensor systems, analytic methods, molecular technologies, computational tools, and bioinformatics-have provided the potential for more accurate and comprehensive exposure science data than ever before. This report also provides a roadmap to take advantage of the technologic innovations and strategic collaborations to move exposure science into the future.

Guidelines for Setting Specific Concentration Limits for Carcinogens in Annex I of Directive 67/548/EEC

Guidelines for Setting Specific Concentration Limits for Carcinogens in Annex I of Directive 67/548/EEC PDF Author:
Publisher:
ISBN:
Category : Carcinogens
Languages : en
Pages : 40

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Book Description


EPA Strategic Plan

EPA Strategic Plan PDF Author: United States. Environmental Protection Agency
Publisher: Agency
ISBN:
Category : Medical
Languages : en
Pages : 112

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Book Description


Toxicokinetics

Toxicokinetics PDF Author:
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 24

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Book Description


NIOSH Manual of Analytical Methods: NIOSH monitoring methods

NIOSH Manual of Analytical Methods: NIOSH monitoring methods PDF Author: John V. Crable
Publisher:
ISBN:
Category : Analytical chemistry
Languages : en
Pages : 818

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Book Description


OECD Guidelines for Testing of Chemicals

OECD Guidelines for Testing of Chemicals PDF Author: Organisation for Economic Co-operation and Development
Publisher: Organisation for Economic Co-operation and Development ; [Montréal : Renouf]
ISBN: 9789264122215
Category : Chemical industry
Languages : en
Pages :

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OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 405: Acute Eye Irritation/Corrosion

OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 405: Acute Eye Irritation/Corrosion PDF Author: OECD
Publisher: OECD Publishing
ISBN: 926418533X
Category :
Languages : en
Pages : 13

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Book Description
This method provides information on health hazard likely to arise from exposure to test substance (liquids, solids and aerosols) by application on the eye. This Test Guideline is intended preferably for use with albino rabbit. The test substance is ...