Characterization of Nonsense Mediated MRNA Decay in Mammalian Cells PDF Download
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Author: Manuel Selg
Publisher:
ISBN:
Category :
Languages : en
Pages : 450
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Book Description
Author: Manuel Selg
Publisher:
ISBN:
Category :
Languages : en
Pages : 450
Get Book Here
Book Description
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 222
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Book Description
Author: Lynne E. Maquat
Publisher: CRC Press
ISBN: 1498713394
Category : Science
Languages : en
Pages : 277
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Book Description
Nonsense-Mediated mRNA Decay is the first book devoted to nonsense-mediated mRNA decay (NMD). The rationale for such a book is the enormous information that studies of NMD have provided on the intricacies of post-transcriptional gene expression. The first five sections of the book are divided according to organism and begin with chapters on S. cere
Author: Ying Cui
Publisher:
ISBN:
Category :
Languages : en
Pages : 422
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Book Description
Author: Lynne E. Maquat
Publisher: Academic Press
ISBN: 9780123745842
Category : Science
Languages : en
Pages : 464
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Book Description
Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, and RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. * Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway * Expert researchers introduce the most advanced technologies and techniques * Offers step-by-step lab instructions, including necessary equipment and reagents
Author: Hongyu Shang
Publisher:
ISBN:
Category :
Languages : en
Pages : 142
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Book Description
Author: Lynne E. Maquat
Publisher: Academic Press
ISBN: 0080922074
Category : Science
Languages : en
Pages : 661
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Book Description
Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. - Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway - Expert researchers introduce the most advanced technologies and techniques to identify mRNA processing, transport, localization and turnover, which are central to the process of gene expression - Offers step-by-step lab instructions, including necessary equipment and reagents
Author: Kirk Richard Anders
Publisher:
ISBN:
Category :
Languages : en
Pages : 242
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Book Description
Author: Kuchma Sherry Lynn
Publisher:
ISBN:
Category :
Languages : en
Pages : 164
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Book Description
Author: Fabrice Lejeune
Publisher: Academic Press
ISBN: 0128044691
Category : Science
Languages : en
Pages : 192
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Book Description
Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD). It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. In addition, the book shows how it may be possible to combine several of these strategies to ultimately improve the efficiency of correction, also suggesting the future goals and objectives to improve treatment modalities in this evolving sphere of personalized medicine. - Features basic biological and clinical constructs that inform the application of genomic data to clinical decision-making - Includes theories and methods that can be used to link bio-molecular and clinical phenotypes so as to enable integrative hypothesis discovery, testing, and downstream evidence-based practice - Provides design patterns and use cases that contextualize the clinical decision-making and evidence-based practice relative to real world requirements and stakeholders
