Essentials of Interventional Cancer Pain Management

Essentials of Interventional Cancer Pain Management PDF Author: Amitabh Gulati
Publisher: Springer
ISBN: 3319996843
Category : Medical
Languages : en
Pages : 510

Get Book Here

Book Description
This text provides a comprehensive review and expertise on various interventional cancer pain procedures. The first part of the text addresses the lack of consistency seen in the literature regarding interventional treatment options for specific cancer pain syndromes. Initially, it discusses primary cancer and treatment-related cancer pain syndromes that physicians may encounter when managing cancer patients. The implementation of paradigms that can be used in treating specific groups of cancer such as breast cancer, follows. The remainder of the text delves into a more common approach to addressing interventional cancer pain medicine. After discussing interventional options that are commonly employed by physicians, the text investigates how surgeons may address some of the more severe pain syndromes, and covers the most important interventional available for our patients, intrathecal drug delivery. Chapters also cover radiologic options in targeted neurolysis and ablative techniques, specifically for bone metastasis, rehabilitation to address patients’ quality of life and function, and integrative and psychological therapies. Essentials of Interventional Cancer Pain Management globally assesses and addresses patients’ needs throughout the cancer journey. Written by experts in the field, and packed with copious tables, figures, and flow charts, this book is a must-have for pain physicians, residents, and fellows.

Essentials of Interventional Cancer Pain Management

Essentials of Interventional Cancer Pain Management PDF Author: Amitabh Gulati
Publisher: Springer
ISBN: 3319996843
Category : Medical
Languages : en
Pages : 510

Get Book Here

Book Description
This text provides a comprehensive review and expertise on various interventional cancer pain procedures. The first part of the text addresses the lack of consistency seen in the literature regarding interventional treatment options for specific cancer pain syndromes. Initially, it discusses primary cancer and treatment-related cancer pain syndromes that physicians may encounter when managing cancer patients. The implementation of paradigms that can be used in treating specific groups of cancer such as breast cancer, follows. The remainder of the text delves into a more common approach to addressing interventional cancer pain medicine. After discussing interventional options that are commonly employed by physicians, the text investigates how surgeons may address some of the more severe pain syndromes, and covers the most important interventional available for our patients, intrathecal drug delivery. Chapters also cover radiologic options in targeted neurolysis and ablative techniques, specifically for bone metastasis, rehabilitation to address patients’ quality of life and function, and integrative and psychological therapies. Essentials of Interventional Cancer Pain Management globally assesses and addresses patients’ needs throughout the cancer journey. Written by experts in the field, and packed with copious tables, figures, and flow charts, this book is a must-have for pain physicians, residents, and fellows.

Neuroimmunology of the Skin

Neuroimmunology of the Skin PDF Author: Richard D. Granstein
Publisher: Springer Science & Business Media
ISBN: 3540359893
Category : Medical
Languages : en
Pages : 248

Get Book Here

Book Description
Much anecdotal information has suggested an influence of psychology and the nervous system on immunity within the skin and the expression of inflammatory skin disorders. Recent years have seen an explosion of knowledge providing a scientific basis for important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin. The results of recent investigations have important implications, not only for an understanding of cutaneous immunity, but also for the development of novel treatments for diseases involving abnormal inflammation or immune reactivity within the skin. This book provides a comprehensive and interdisciplinary review of the molecular biology, cell biology, biochemistry and clinical aspects of nervous system–immune system interactions within the skin. It includes contributions from leading world experts in these areas. The contents are relevant to both investigators and clinicians interested in the skin, its functions and its disorders.

The Challenge of CMC Regulatory Compliance for Biopharmaceuticals

The Challenge of CMC Regulatory Compliance for Biopharmaceuticals PDF Author: John Geigert
Publisher: Springer
ISBN: 3030137546
Category : Medical
Languages : en
Pages : 446

Get Book Here

Book Description
Biopharmaceuticals (i.e., biological medicines sourced from genetically-engineered living systems) for treatment of human diseases have become a significant percentage of the pharmaceutical industry. And not just the recombinant DNA-derived proteins and monoclonal antibodies (both from the innovators and biosimilars); but now, an increasing awareness of the importance of gene therapy and genetically engineered cellular medicinal products. These biopharmaceuticals are being developed by many companies whose Chemistry, Manufacturing & Control (CMC) teams have varying degrees of familiarity or experience with the CMC strategy and regulatory compliance requirements for these challenging products. Companies clearly plan out the strategy for their clinical study plans, but frequently, the development of a strategy for CMC is an afterthought. Coupled with the complexity of the biopharmaceutical manufacturing processes and products, and this can be a recipe for disaster. The third edition of this book provides insights and practical guidance for the CMC teams to develop an acceptable cost-effective, risk-based CMC regulatory compliance strategy for all biopharmaceuticals (recombinant proteins, monoclonal antibodies, genetically engineered viruses and genetically engineered human cells) from early clinical stage development through market approval. The third edition of this book provides added coverage for the biosimilars, antibody drug conjugates (ADCs), bispecific antibodies, genetically engineered viruses, and genetically engineered cells. This third edition of the book also addresses the heightened pressure on CMC regulatory compliance timelines due to the introduction of expedited clinical pathways moving the clinical development closer to a seamless phase process (e.g., FDA Breakthrough Therapy designation, CBER Regenerative Medicine Advanced Therapy (RMAT) designation, EMA Priority Medicines (PRIME) designation). The Challenge of CMC Regulatory Compliance for Biopharmaceuticals is essential, practical information for all pharmaceutical development scientists, Manufacturing and Quality Unit staff, Regulatory Affairs personnel, and senior management involved in the manufacture of biopharmaceuticals.

Foodborne Microbial Pathogens

Foodborne Microbial Pathogens PDF Author: Arun K. Bhunia
Publisher: Springer
ISBN: 1493973495
Category : Technology & Engineering
Languages : en
Pages : 377

Get Book Here

Book Description
This book primarily covers the general description of foodborne pathogens and their mechanisms of pathogenesis, control and prevention, and detection strategies, with easy-to-comprehend illustrations. The book is an essential resource for food microbiology graduate or undergraduate students, microbiology professionals, and academicians involved in food microbiology, food safety, and food defense-related research or teaching. This new edition covers the significant progress that has been made since 2008 in understanding the pathogenic mechanism of some common foodborne pathogens, and the host-pathogen interaction. Foodborne and food-associated zoonotic pathogens, responsible for high rates of mortality and morbidity, are discussed in detail. Chapters on foodborne viruses, parasites, molds and mycotoxins, and fish and shellfish are expanded. Additionally, chapters on opportunistic and emerging foodborne pathogens including Nipah virus, Ebola virus, Aeromonas hydrophila, Brucella abortus, Clostridium difficile, Cronobacter sakazakii, and Plesiomonas shigelloides have been added. The second edition contains more line drawings, color photographs, and hand-drawn illustrations.

Encyclopedia of Cell Biology

Encyclopedia of Cell Biology PDF Author:
Publisher: Academic Press
ISBN: 0123947960
Category : Science
Languages : en
Pages : 2972

Get Book Here

Book Description
The Encyclopedia of Cell Biology, Four Volume Set offers a broad overview of cell biology, offering reputable, foundational content for researchers and students across the biological and medical sciences. This important work includes 285 articles from domain experts covering every aspect of cell biology, with fully annotated figures, abundant illustrations, videos, and references for further reading. Each entry is built with a layered approach to the content, providing basic information for those new to the area and more detailed material for the more experienced researcher. With authored contributions by experts in the field, the Encyclopedia of Cell Biology provides a fully cross-referenced, one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences. Fully annotated color images and videos for full comprehension of concepts, with layered content for readers from different levels of experience Includes information on cytokinesis, cell biology, cell mechanics, cytoskeleton dynamics, stem cells, prokaryotic cell biology, RNA biology, aging, cell growth, cell Injury, and more In-depth linking to Academic Press/Elsevier content and additional links to outside websites and resources for further reading A one-stop resource for students, researchers, and teaching faculty across the biological and medical sciences

Characteristics of the OTOX Model CTL Oxygen Sensor

Characteristics of the OTOX Model CTL Oxygen Sensor PDF Author: J. E. Chilton
Publisher:
ISBN:
Category : Gas-detectors
Languages : en
Pages : 24

Get Book Here

Book Description


Microbes

Microbes PDF Author: Prakash S. Bisen
Publisher: John Wiley & Sons
ISBN: 1118311892
Category : Science
Languages : en
Pages : 731

Get Book Here

Book Description
An accessible introduction to the world of microbes—from basic microbe biology through industrial applications Microbes affect our lives in a variety of ways—playing an important role in our health, food, agriculture, and environment. While some microbes are beneficial, others are pathogenic or opportunistic. Microbes: Concepts and Applications describes basic microbe biology and identification and shows not only how they operate in the subfields of medicine, biotechnology, environmental science, bioengineering, agriculture, and food science, but how they can be harnessed as a resource. It provides readers with a solid grasp of etiologic agents, pathogenic processes, epidemiology, and the role of microbes as therapeutic agents. Placing a major emphasis on omics technology, the book covers recent developments in the arena of microbes and discusses their role in industry and agriculture, as well as in related fields such as immunology, cell biology, and molecular biology. It offers complete discussions of the major bacterial, viral, fungal, and parasitic pathogens; includes information on emerging infectious diseases, antibiotic resistance, and bioterrorism; and talks about the future challenges in microbiology. The most complete treatment of microbial biology available, Microbes features eye-opening chapters on: Human and Microbial World Gene Technology: Application and Techniques Molecular Diagnostic and Medical Microbiology Identification and Classification of Microbes Diversity of Microorganisms Microbes in Agriculture Microbes as a Tool for Industry and Research Complete with charts and figures, this book is an invaluable textbook for university teachers, students, researchers, and people everywhere who care about microorganisms.

Toxins and Signal Transduction

Toxins and Signal Transduction PDF Author: Yehuda Gutman
Publisher: CRC Press
ISBN: 9789057020780
Category : Science
Languages : en
Pages : 520

Get Book Here

Book Description
Of the multitude of toxins known and the enormous variety of effects they cause, of particular interest are those that influence signal transduction. Intercellular communication by chemical signals is essential for the functioning of multicellular organisms. Many toxins exert their biological effects by interfering with the signal transduction initiated by these chemicals (hormones, transmitters, growth factors, and other mediators). Up-to-date information is provided by outstanding experts, who discuss the molecular mechanisms involved in the action of many toxins, as well as the use of toxins as informative tools with which to study signal transduction and their potential therapeutic usage. This volume contains useful information for the experimentalist interested in toxins or in signal transduction, as well as for the reader interested in gaining a comprehensive overview of the field. The Cellular and Molecular Mechanisms of Toxin Action series will include monographs on signal transduction, secretory systems, cytoskeleton, selective neurotoxicity of natural, recombinant and chimeric toxins giving a broader emphasis on the mechanism of action, structure-function relationship, and use of toxins as research tools and their therapeutic applications.

Vascular Anesthesia

Vascular Anesthesia PDF Author: Joel A. Kaplan
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 456

Get Book Here

Book Description
This comprehensive text delivers cutting-edge scientific knowledge and expert clinical guidance on anesthesia for the vascular surgical patient or the patient with cardiac disease undergoing major noncardiac surgery. It covers cardiovascular anatomy, physiology, and pharmacology; preoperative assessment and management, specific perioperative considerations, and postoperative management. This 2nd Edition features eight completely rewritten chapters and six new chapters. Extensive updates throughout reflect all the new procedures, drugs, techniques, and monitoring modalities that have emerged over the last decade. Delivers cutting-edge scientific knowledge that serves as a basis for clinical practice. Provides comprehensive coverage of anesthesia, including cardiovascular anatomy, physiology, and pharmacology preoperative assessment and management specific perioperative considerations and postoperative management. Integrates recent developments from the fields of anesthesiology, cardiology, cardiovascular pharmacology, vascular surgery, and critical care medicine to present a complete clinical picture Offers fresh perspectives from many new contributors who are leaders in their fields. Explores all the new procedures, drugs, techniques, and monitoring modalities that have emerged over the last decade. Devotes more coverage to regional anesthesia or combined regional and general anesthesia for modification of stress responses, improved pain control, better wound healing, and control of inflammatory/immunomodulatory changes associated with surgery. Places increased emphasis on the physiology, diseases, and surgery of the peripheral vasculature throughout, including a new chapter on The Peripheral Circulation in Patients with Vascular Disease (Chapter 1). Includes a new chapter on Imaging of the Vasculature(Chapter 2), that is completely up to date and easy to read. Covers anesthesia and perioperative care for all of the latest procedures, including new information on minimally invasive techniques and new chapters on Interventional Vascular Radiologic Procedures (Chapter 4) and Choice of Invasive vs. Noninvasive Surgery (Chapter 7). Features expanded material on postoperative care, especially on new techniques for pain management, and includes new chapters on Respiratory Complications and Management (Chapter 18) and Ethical Decisions/End of Life Care in Patients with Vascular Disease (Chapter 20).

Integrated Electrophysical Agents[Formerly Entitled Electrotherapy: Evidence-Based Practice]

Integrated Electrophysical Agents[Formerly Entitled Electrotherapy: Evidence-Based Practice] PDF Author: Tim Watson
Publisher: Elsevier
ISBN: 9780702051517
Category : Medical
Languages : en
Pages : 432

Get Book Here

Book Description
Electrophysical Modalities (formerly Electrotherapy: Evidence-Based Practice) is back in its 13th edition, continuing to uphold the standard of clinical research and evidence base for which it has become renowned. This popular textbook comprehensively covers the use of electrotherapy in clinical practice and includes the theory which underpins that practice. Over recent years the range of therapeutic agents involved and the scope for their use have greatly increased and the new edition includes and evaluates the latest evidence and most recent developments in this fast-growing field. Tim Watson is joined by co-editor Ethne Nussbaum and both bring years of clinical, research and teaching experience to the new edition, with a host of new contributors, all leaders in their specialty.