Characterisation of Histone MRNA 3' End Processing in the Yeast Saccharomyces Cerevisiae PDF Download
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Author: Susan Campbell
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Susan Campbell
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Christoph Mathias Egli
Publisher:
ISBN:
Category : Genetic transcription
Languages : en
Pages : 124
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Author: Wolfgang Hübner
Publisher:
ISBN:
Category :
Languages : en
Pages : 221
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Author: Karen Renee Christie
Publisher:
ISBN:
Category :
Languages : en
Pages : 600
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Regulation of the process of transcriptional elongation is an important control mechanism in the expression of some genes. To fully understand this form of regulation will require better understanding of the functions of transcription elongation factors. The goal of this work was to characterize the transcription elongation factor TFIIS from Saccharomyces cerevisiae, originally called P37. I demonstrated that, like the mammalian TFIIS proteins, the yeast protein stimulates RNA polymerase II to cleave the nascent RNA transcript and to read-through an intrinsic block to elongation. Investigation of the protein-protein contacts between TFIIS and RNA polymerase II indicated that the carboxyl-terminal domain of the largest subunit, subunit four, and subunit seven of the polymerase are not required for TFIIS to promote cleavage and read-through by the polymerase. In addition the carboxyl-terminal half of the yeast TFIIS protein is sufficient for both of these in vitro activities. This result is consistent with the previous results demonstrating the carboxyl-terminus of mouse TFIIS was sufficient to activate RNA polymerase in vitro.
Author: Jonathan R. Beckwith
Publisher: CSHL Press
ISBN: 9780879691646
Category : Bacterial genetics
Languages : en
Pages : 352
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Author:
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Category : Medicine
Languages : en
Pages : 874
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Author: Paula Grabowski
Publisher: BoD – Books on Demand
ISBN: 9533075570
Category : Medical
Languages : en
Pages : 262
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Book Description
RNA functions broadly as informational molecule, genome, enzyme and machinery for RNA processing. While these functions reflect ancient activities, they also remain vital components of contemporary biochemical pathways. In eukaryotic cells RNA processing impacts the biogenesis of RNA molecules of essentially every shape and function. The collection of articles in this volume describes the current state of understanding of the broad array of RNA processing events in animal and plant cells, key unanswered questions, and cutting edge approaches available to address these questions. Some questions discussed in this volume include, how viruses subvert the RNA processing machinery of the host cell, how the coordination of co-transcriptional RNA processing is regulated at the level of chromatin, the status of RNA processing in plant organelles, and how micro RNA machinery is biosynthesized and regulated.
Author:
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ISBN:
Category : Medicine
Languages : en
Pages : 1488
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Author:
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ISBN:
Category : Medicine
Languages : en
Pages : 1504
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Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author: Witold Filipowicz
Publisher: Springer Science & Business Media
ISBN: 9400903537
Category : Science
Languages : en
Pages : 419
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Book Description
A recent volume of this series (Signals and Signal Transduction Pathways in Plants (K. Palme, ed.) Plant Molecular Biology 26, 1237-1679) described the relay races by which signals are transported in plants from the sites of stimuli to the gene expression machinery of the cell. Part of this machinery, the transcription apparatus, has been well studied in the last two decades, and many important mechanisms controlling gene expression at the transcriptional level have been elucidated. However, control of gene expression is by no means complete once the RNA has been produced. Important regulatory devices determine the maturation and usage of mRNA and the fate of its translation product. Post-transcriptional regulation is especially important for generating a fast response to environmental and intracellular signals. This book summarizes recent progress in the area of post-transcriptional regulation of gene expression in plants. 18 chapters of the book address problems of RNA processing and stability, regulation of translation, protein folding and degradation, as well as intracellular and cell-to-cell transport of proteins and nucleic acids. Several chapters are devoted to the processes taking place in plant organelles.
