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Author: Georg W. Kreutzberg
Publisher: Springer Science & Business Media
ISBN: 3642706649
Category : Science
Languages : en
Pages : 313
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Book Description
Cells do not normally live as single entities but are grouped together in specific functional and structural configurations in various tissues. Intra cellular mechanisms maintain cellular viability and provide the means necessary for their specific cellular functions. The interaction between cells is maintained by mechanisms involving extracellular signalling. Such extracellular mechanisms may include special properties of the cell surface which involve immediate cell contact, but may also represent mechanisms which act at a distance and are mediated via special secretions and/or re ceptors. Recent studies on cell-cell contact have tended to stress cell sur face components directly mediating cellular interactions; the extracellular medium as a metabolically active compartment has been rather neglected. However, it represents a vital medium through which cells communicate, being important in, for example, chemotaxis in primitive organisms, and in devel~ment and in the coordination of multiple functions in multi cellular 0 ganisms. It is not surprising, therefore, that a number of mole cular me anisms have developed together with increasing biological complexi during evolution. Two aspects of the extracellular space have received increasing attention in the last few years. First, several macro molecules such as collagen, laminin and fibronectin have been identified as components of an extracellular matrix giving a structural dimension to the extracellular compartment.
Author: Georg W. Kreutzberg
Publisher: Springer Science & Business Media
ISBN: 3642706649
Category : Science
Languages : en
Pages : 313
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Book Description
Cells do not normally live as single entities but are grouped together in specific functional and structural configurations in various tissues. Intra cellular mechanisms maintain cellular viability and provide the means necessary for their specific cellular functions. The interaction between cells is maintained by mechanisms involving extracellular signalling. Such extracellular mechanisms may include special properties of the cell surface which involve immediate cell contact, but may also represent mechanisms which act at a distance and are mediated via special secretions and/or re ceptors. Recent studies on cell-cell contact have tended to stress cell sur face components directly mediating cellular interactions; the extracellular medium as a metabolically active compartment has been rather neglected. However, it represents a vital medium through which cells communicate, being important in, for example, chemotaxis in primitive organisms, and in devel~ment and in the coordination of multiple functions in multi cellular 0 ganisms. It is not surprising, therefore, that a number of mole cular me anisms have developed together with increasing biological complexi during evolution. Two aspects of the extracellular space have received increasing attention in the last few years. First, several macro molecules such as collagen, laminin and fibronectin have been identified as components of an extracellular matrix giving a structural dimension to the extracellular compartment.
Author: R. Lipowsky
Publisher: Elsevier
ISBN: 0080541917
Category : Technology & Engineering
Languages : en
Pages : 537
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Book Description
The first volume of the Handbook deals with the amazing world of biomembranes and lipid bilayers. Part A describes all aspects related to the morphology of these membranes, beginning with the complex architecture of biomembranes, continues with a description of the bizarre morphology of lipid bilayers and concludes with technological applications of these membranes. The first two chapters deal with biomembranes, providing an introduction to the membranes of eucaryotes and a description of the evolution of membranes. The following chapters are concerned with different aspects of lipids including the physical properties of model membranes composed of lipid-protein mixtures, lateralphase separation of lipids and proteins and measurement of lipid-protein bilayer diffusion. Other chapters deal with the flexibility of fluid bilayers, the closure of bilayers into vesicles which attain a large variety of different shapes, and applications of lipid vesicles and liposomes. Part B covers membrane adhesion, membrane fusion and the interaction of biomembranes withpolymer networks such as the cytoskeleton. The first two chapters of this part discuss the generic interactions of membranes from the conceptual point of view. The following two chapters summarize the experimental work on two different bilayer systems. The next chapter deals with the process ofcontact formation, focal bounding and macroscopic contacts between cells. The cytoskeleton within eucaryotic cells consists of a network of relatively stiff filaments of which three different types of filaments have been identified. As explained in the next chapter much has been recently learned aboutthe interaction of these filaments with the cell membrane. The final two chapters deal with membrane fusion.
Author: E. C. Foulkes
Publisher: CRC Press
ISBN: 9781439806029
Category : Medical
Languages : en
Pages : 172
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Book Description
Using this concise yet complete introduction to all aspects of biological membranes and their responses to toxicants, the reader will understand the role of cell membranes in controlling uptake, distribution, extrusion and excretion of toxic xenobiotics. The book also covers the historical background and critically evaluates some of the experimenta
Author: Joseph G. Brand
Publisher: CRC Press
ISBN: 1000444619
Category : Technology & Engineering
Languages : en
Pages : 558
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Book Description
This book focuses on the initial biochemical and biophysical aspects of taste and olfaction. It is intended for a wide audience, both those already familiar with the chemical senses and those biochemists and neuro-biologists interested in gaining an appreciation of this rapidly expanding discipline.
Author: Volker Neuhoff
Publisher: Springer Science & Business Media
ISBN: 3642764703
Category : Science
Languages : en
Pages : 398
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Book Description
Summarizing research progress achieved in 32 areas of cell biology covered in this series, this volume places special emphasis on the following topics: recognition in parasitic and symbiotic systems - the molecular biology and genetics of susceptibility and resistance of plants and animals to pathogens, parasites and symbionts - the cell to cell recognition and differentiation - the most challenging problems in developmental biology of plants and animals - the plasticity in cell to cell communication which plays a major role in cell differentiation and function.
Author: Herbert Zimmermann
Publisher: Springer Science & Business Media
ISBN: 3642731724
Category : Science
Languages : en
Pages : 547
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Book Description
Major progresses in the study of the cellular and molecular basis of synaptic transmission of nerve cells are highlighted. Each individual contribution gives an overview of the subject, presenting a description of the technical approach and considering future perspectives of the developments in the field. Topics range from historical aspects of the development of biochemical studies on synaptic transmission to the most advanced techniques applicable in morphological and functional studies of the nerve terminal. Studies on synaptic vesicles, the regulation of presynaptic transmitter synthesis, transmitter-release and especially the molecular structure and function of presynaptic ion channels and of transmitter receptors offer a detailed insight into synaptic events.
Author: Yigal H. Ehrlich
Publisher: Springer Science & Business Media
ISBN: 1461548691
Category : Medical
Languages : en
Pages : 229
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Book Description
Numerous studies have proven the biological basis of memory formation and have begun to identify the biochemical traces and cellular circuits that are formed by experience, and which participate int the storage of information in the brain, its retention for long durations, and its retrieval upon demand. Cells in the nervous system have the capability of undergoing extremely long-lasting alterations in response to hormonal, pharmacological, and environmental stimulations. The mechanisms underlying this neuronal plasticity are activated by experiential inputs and operate in the process of learning and the formation of memories in the brain. This volume presents research areas which have not been highlighted in the past. In addition to studies on the involement of functional proteins in neuronal adaptation, this volume presents recent developments on the critical roles of bioactive lipids and nucleotides in these processes. In addition to the widely studied role of second messengers, a review of studies on extracellular phosphorylation systems operating on the surface of brain neurons is presented.The first section of the volume presents studies of basic mechanisms operating in a wide range of adaptive processes. The second section presents recent advances in investigations that have demonstrated the clinical implications of this research. These include: state of the art use of transgenic models in studies of molecular and cellular mechanisms implicated in familial Alzheimer's disease and Amyotrophic Lateral Sclerosis; studies of specific proteins implicated in Alzheimer's disease, including an adapter that binds to the beta-amyloid precurser protein (beta-APP) and the microtubular protein Tau and its membrane-bound counterpart. The advantages of using cell culture models for elucidating the causes of neuronal degeneration and for identifying mechanisms of neuroprotection are also presented among the chapters in the section on clinical implications.
Author: Peter Ghosh
Publisher: CRC Press
ISBN: 1000006441
Category : Medical
Languages : en
Pages : 256
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Book Description
First Published in 1988, this book documents the role, biology, and structure of the Intervertebral Disc. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Medicine, Chiropractors, and other practitioners in their respective fields.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 762
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Book Description
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1676
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Book Description
First multi-year cumulation covers six years: 1965-70.
