Disorders of Hemoglobin

Disorders of Hemoglobin PDF Author: Martin H. Steinberg
Publisher: Cambridge University Press
ISBN: 0521875196
Category : Medical
Languages : en
Pages : 883

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Book Description
Completely revised new edition of the definitive reference on disorders of hemoglobin.

Disorders of Hemoglobin

Disorders of Hemoglobin PDF Author: Martin H. Steinberg
Publisher: Cambridge University Press
ISBN: 0521875196
Category : Medical
Languages : en
Pages : 883

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Book Description
Completely revised new edition of the definitive reference on disorders of hemoglobin.

Molecular Biology of the Cell

Molecular Biology of the Cell PDF Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0

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Cellular and Molecular Regulation of Hemoglobin Switching

Cellular and Molecular Regulation of Hemoglobin Switching PDF Author: George Stamatoyannopoulos
Publisher: Grune & Stratton, Incorporated
ISBN:
Category : Medical
Languages : en
Pages : 828

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Cumulated Index Medicus

Cumulated Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 804

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The Molecular Basis of Blood Diseases

The Molecular Basis of Blood Diseases PDF Author: George Stamatoyannopoulos
Publisher: Saunders
ISBN:
Category : Medical
Languages : en
Pages : 1080

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Book Description
The superb Third Edition of this popular text covers all the recent groundbreaking developments which have taken place in this field. Comprehensively revised, it presents all the latest findings on the molecular bases of blood cell functions and disease mechanisms and the impact of these discoveries on the state of medicine. This edition includes new chapters such as signaling and antigen presentation by B-lymphocytes, molecular oncogenesis and more!

The Molecular Switch

The Molecular Switch PDF Author: Rob Phillips
Publisher: Princeton University Press
ISBN: 0691200246
Category : Science
Languages : en
Pages : 436

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Book Description
A signature feature of living organisms is their ability to carry out purposeful actions by taking stock of the world around them. To that end, cells have an arsenal of signaling molecules linked together in signaling pathways, which switch between inactive and active conformations. The Molecular Switch articulates a biophysical perspective on signaling, showing how allostery—a powerful explanation of how molecules function across all biological domains—can be reformulated using equilibrium statistical mechanics, applied to diverse biological systems exhibiting switching behaviors, and successfully unify seemingly unrelated phenomena. Rob Phillips weaves together allostery and statistical mechanics via a series of biological vignettes, each of which showcases an important biological question and accompanying physical analysis. Beginning with the study of ligand-gated ion channels and their role in problems ranging from muscle action to vision, Phillips then undertakes increasingly sophisticated case studies, from bacterial chemotaxis and quorum sensing to hemoglobin and its role in mammalian physiology. He looks at G-protein coupled receptors as well as the role of allosteric molecules in gene regulation. Phillips concludes by surveying problems in biological fidelity and offering a speculative chapter on the relationship between allostery and biological Maxwell demons. Appropriate for graduate students and researchers in biophysics, physics, engineering, biology, and neuroscience, The Molecular Switch presents a unified, quantitative model for describing biological signaling phenomena.

Renaissance Of Sickle Cell Disease Research In The Genome Era

Renaissance Of Sickle Cell Disease Research In The Genome Era PDF Author: Betty Pace
Publisher: World Scientific
ISBN: 1908979917
Category : Science
Languages : en
Pages : 394

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Book Description
The Human Genome Project has spawned a Renaissance of research faced with the daunting expectation of personalized medicine for individuals with sickle cell disease in the Genome Era. This book offers a comprehensive and timeless account of emerging concepts in clinical and basic science research, and community concerns of health disparity to educate professionals, students and the general public about meeting this challenging expectation. Contributions from physicians, research scientists, scientific administrators and community workers make Renaissance of Sickle Cell Disease Research in the Genome Era unique among the catalogue of books on this genetic disorder.Part 1 offers detailed review of the National Heart Lung and Blood Institute's leadership role in funding sickle cell research, as well as developing progressive research initiatives and the predicted impact of the Human Genome Project. Part 2 gives an account of several clinical research perspectives based on the Cooperative Study of Sickle Cell Disease. These include recommendations for newborn screening, pain management, stroke, transfusion therapy and pediatric and adult healthcare. Part 3 offers novel insights into basic science research progress and the impact of the Human Genome Project on the direction of hemoglobinopathy research, including hemoglobin switching, bone marrow transplantation and gene therapy. Part 4 engages the reader in a culture-based discussion of the stigma attached to sickle cell disease in the African American community and the apprehensions about genetic research in this community. It concludes with a global perspective on sickle cell disease from African, European and American experiences. For readers seeking a definitive account of sickle cell disease appropriate for students, researchers and community workers, this collaborative effort is an ideal textbook./a

Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis

Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis PDF Author: Ivan N. Rich
Publisher: Springer Science & Business Media
ISBN: 3642726526
Category : Science
Languages : en
Pages : 456

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Book Description
Molecular biology has provided a tool with which problems in cellular differentiation can be answered. Recombinant DNA technology has been used to obtain quantities of the erythropoietic hormone, erythropoietin. The availability of the hormone has provided a much-needed impetus in learning how erythropoiesis is controlled. Knowledge of the genetic components, transcription and translation of the erythropoietin gene and finally the release of the mature hormone under various physiological conditions should be forthcoming in the near future. This volume will give the reader some indication as to the different aspects of erythropoiesis. They include the regulation of production of the hormone under normal and abnormal conditions, ontogeny and cellular interactions and the assay of the hormone itself.

Recombinant DNA Research

Recombinant DNA Research PDF Author:
Publisher:
ISBN:
Category : DNA
Languages : en
Pages : 516

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Published Scientific Papers of the National Institutes of Health

Published Scientific Papers of the National Institutes of Health PDF Author: National Institutes of Health (U.S.)
Publisher:
ISBN:
Category :
Languages : en
Pages : 524

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Book Description