ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes

ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes PDF Author: J.A. Kellum
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318024074
Category : Medical
Languages : en
Pages : 218

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Book Description
Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based is the discovery phase? How can we incorporate the new biomarkers in the AKI conceptual model describing the evolution from susceptibility to insult, decreased GFR and organ death? Even if we have a positive biomarker pattern and we can identify patients at risk or patients with early or even subclinical AKI, how is this information affecting our clinical behavior and practice? The second part is dedicated to the appraisal of the current knowledge about the pathophysiological mechanisms involved in different forms of CRS: it contains contributions on the state-of-the-art knowledge and practice of CRS, particularly focusing on the pathophysiology of the five subtypes. Acute and chronic mechanisms of damage are explored in depth, with particular attention to the primacy of organ involvement and the subsequent pathways of organ crosstalk.Presenting the most recent research in the field of biomarkers, AKI and CRS, this publication is an important educational tool for advanced investigators and clinical experts, but also for students and fellows.

ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes

ADQI Consensus on AKI Biomarkers and Cardiorenal Syndromes PDF Author: J.A. Kellum
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318024074
Category : Medical
Languages : en
Pages : 218

Get Book Here

Book Description
Associated with both acute kidney injury (AKI) and cardio-renal syndromes (CRS), new biomarkers represent both a popular area of investigation and a new opportunity for advancement of therapy. This book contains the resolutions of the most recent ADQI conferences on biomarkers in AKI (Dublin) and on cardio-renal syndromes (Venice). The first part answers specific questions about new biomarkers and their use and utility in AKI: What are the most suitable candidate molecules and physiologic measures, how solid and evidence based is the discovery phase? How can we incorporate the new biomarkers in the AKI conceptual model describing the evolution from susceptibility to insult, decreased GFR and organ death? Even if we have a positive biomarker pattern and we can identify patients at risk or patients with early or even subclinical AKI, how is this information affecting our clinical behavior and practice? The second part is dedicated to the appraisal of the current knowledge about the pathophysiological mechanisms involved in different forms of CRS: it contains contributions on the state-of-the-art knowledge and practice of CRS, particularly focusing on the pathophysiology of the five subtypes. Acute and chronic mechanisms of damage are explored in depth, with particular attention to the primacy of organ involvement and the subsequent pathways of organ crosstalk.Presenting the most recent research in the field of biomarkers, AKI and CRS, this publication is an important educational tool for advanced investigators and clinical experts, but also for students and fellows.

Specialist Training in Cardiology

Specialist Training in Cardiology PDF Author: H. Purcell
Publisher: Elsevier Health Sciences
ISBN: 0723433216
Category : Biochemical markers
Languages : en
Pages : 388

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Book Description
HIGHLY COMMENDED IN THE CARDIOLOGY CATEGORY, BMA AWARDS 2006! Specialist Training in Cardiology is written for those doctors starting their career in this specialty (or in general internal medicine). The text presents a succinct account of the subject concentrating on diagnostic techniques, treatment and management. Throughout extensive use is made of radiographs, drawings, lists and tables. The aim is to provide a 'bridge' between introductory undergraduate texts and the very large and expensive major reference works. Wherever possible evidence-based treatment options are given and referenced. A detailed list of further reading is also provided. Series aimed at specialist registrar level Succinct style making use of bullet points, boxes, tables etc. Highly accessible four-colour design

Cardiorenal Syndrome in Heart Failure

Cardiorenal Syndrome in Heart Failure PDF Author: W. H. Wilson Tang
Publisher: Springer Nature
ISBN: 3030210332
Category : Medical
Languages : en
Pages : 277

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Book Description
This comprehensive manual reviews the management of cardiorenal syndrome in heart failure. Chapters are structured in a practically applicable and easy-to-follow format with realistic case vignettes and key clinical management questions and answers, followed by a brief discussion of underlying pathophysiological mechanisms of a patient with cardiorenal syndrome. Building from this case, key questions are posed that are relevant to the clinical management and then potential evidence-based treatment strategies are proposed. Topics covered include loop diuretic resistance in acute and chronic heart failure, abdominal congestion, low output failure and potential diuretic complications due to hyponatremia. Cardiorenal Syndrome in Heart Failure thoroughly reviews cardiorenal syndrome from the perspective of both the cardiologist and nephrologist. Its case-based approach makes it an ideal resource for both practising and trainee cardiology and nephrology practitioners.

Textbook of Cardiorenal Medicine

Textbook of Cardiorenal Medicine PDF Author: Peter A. McCullough
Publisher: Springer Nature
ISBN: 3030574601
Category : Medical
Languages : en
Pages : 381

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Book Description
This textbook provides a practical and board-driven resource to describe and define the emerging field of cardiorenal medicine. Covering all aspects of the topic with depth and relevance, this groundbreaking reference brings together experts at the nexus between cardiovascular and renal medicine to provide an exception reference to educate in this critical area of modern medicine. It describes how the heart and kidneys are inextricably linked via hemodynamic, neural, hormonal and cellular signaling systems and, concentrating on disease-based coverage, goes on to review emerging concepts in epidemiology, pathogenesis, screening, diagnosis and the management of cardiorenal syndromes, all extensively illustrated and containing features to support scholarship in the field. Textbook of Cardiorenal Medicine provides consistent chapter organization, clear design and engaging text to define the diagnosis, treatment, intervention and surgical aspects of the full range of conditions encountered within this area of medicine. It is therefore an essential resource to all involved in the management of cardiorenal disease.

Managing the Kidney when the Heart is Failing

Managing the Kidney when the Heart is Failing PDF Author: George L. Bakris
Publisher: Springer Science & Business Media
ISBN: 1461436915
Category : Medical
Languages : en
Pages : 127

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Book Description
The presence of Chronic Kidney Disease (CKD) increases the risk of death from cardiovascular causes and makes the management of heart failure difficult. The coexistence of CKD and heart failure is increasing in prevalence worldwide and requires a unique and subtle approach to patient management. Managing the Kidney in Heart Failure focuses on the therapeutic management of cardio renal patients. Common heart and kidney failure conditions are presented along with treatment scenarios aimed to reduce cardiovascular mortality and preserve kidney function. Co-authored by a Nephrologist and Cardiologist, each chapter of this concise and practical handbook offers a unified perspective to these chronic conditions.

Oxford Textbook of Clinical Nephrology

Oxford Textbook of Clinical Nephrology PDF Author: Neil N. Turner
Publisher: Oxford University Press
ISBN: 0191017655
Category : Medical
Languages : en
Pages : 3045

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Book Description
This fourth edition of the Oxford Textbook of Clinical Nephrology builds on the success and international reputation of the publication as an important resource for the practising clinician in the field. It provides practical, scholarly, and evidence-based coverage of the full spectrum of clinical nephrology, written by a global faculty of experts. The most relevant and important reference to clinical nephrology, this is an authoritative and comprehensive textbook combining the clinical aspects of renal disease essential to daily clinical practice with extensive information about the underlying basic science and current evidence available. Each section of the textbook has been critically and comprehensively edited under the auspices of a leading expert in the field. This new edition has been significantly expanded and reapportioned to reflect developments and new approaches to topics, and includes treatment algorithms to aid and enhance patient care where possible. The fourth edition offers increased focus on the medical aspects of transplantation, HIV-associated renal disease, and infection and renal disease, alongside entirely new sections on genetic topics and clinical and physiological aspects of fluid/electrolyte and tubular disorders. The emphasis throughout is on marrying advances in scientific research with clinical management. Richly illustrated throughout in full colour, this is a truly modern and attractive edition which reinforces the Oxford Textbook of Clinical Nephrology's position as an indispensable reference work of consistent quality and reliability. Enriched and refined by careful revision, this new edition continues the tradition of excellence. This print edition of The Oxford Textbook of Clinical Nephrology comes with a year's access to the online version on Oxford Medicine Online. By activating your unique access code, you can read and annotate the full text online, follow links from the references to primary research materials, and view, enlarge and download all the figures and tables. Oxford Medicine Online is mobile optimized for access when and where you need it.

Cardiorenal Syndrome

Cardiorenal Syndrome PDF Author: Adel E. Berbari
Publisher: Springer Science & Business Media
ISBN: 8847014638
Category : Medical
Languages : en
Pages : 388

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Book Description
Chronic kidney disease with a worldwide prevalence of 10% in the general population is emerging as a major public health priority. Renal dysfunction is associated with a high risk for cardiovascular complications. The relationship between renal insufficiency and cardiovascular disease, termed the cardiorenal syndrome exists whether impairment of renal function is a consequence of primary renal parenchymal disease or primary heart disease. Several pathophysiologic mechanisms have been postulated to explain the relationship between renal dysfunction and cardiovascular disease. Recent studies indicate an integrated response of the vascular smooth muscles and glomerular mesangial cells to traditional and uremia related cardiovascular risk factors. Traditional risk factors can incite renal impairment and cardiac damage. As renal function deteriorates, uremia-related risk factors play an increasing role both in reduction in glomerular filtration rate and cardiovascular damage. Several uremia related factors such as uncontrolled hypertension, disturbed glucose insulin metabolism, microalbuminuria, phosphate retention, secondary hyperparathyroidism, myocardial and vascular calcification, hypertensive-uremic cardiomyopathy, inflammation, oxidant injury, and neurohormonal dysregulation have been implicated in the pathogenesis of the cardiorenal syndrome. Recent data suggest that management of the cardiorenal syndrome requires aggressive control of traditional risk factors as well novel approaches to prevent or reverse uremia –related processes. This book provides a comprehensive update analysis of our current understanding of the cardiorenal syndrome including epidemiology, pathophysiologic mechanisms, and therapeutic approaches.

Congestive Heart Failure

Congestive Heart Failure PDF Author: Jeffrey D. Hosenpud
Publisher: Springer Science & Business Media
ISBN: 1461383153
Category : Medical
Languages : en
Pages : 772

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Book Description
This book is the first to approach the field of congestive heart failure as a true subspecialty of cardiology and cardiovascular surgery. The text discusses the entire field of congestive heart failure: the basic pathophysiologic mechanisms; the underlying diseases; the effects of heart failure on the remainder of circulation; the mechanisms and results of pharmacologic therapy; the multiple surgical and multidisciplinary approaches to end-stage heart disease; and the ultimate prognosis of congestive heart failure in all of the areas of heart failure management. Thus, this text uniquely puts into perspective all of the features of congestive heart failure and its management for the cardiologist, cardiovascular surgeon, and general internist.

Acute Heart Failure

Acute Heart Failure PDF Author: Alexandre Mebazaa
Publisher: Springer Science & Business Media
ISBN: 1846287820
Category : Medical
Languages : en
Pages : 922

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Book Description
For many years, there has been a great deal of work done on chronic congestive heart failure while acute heart failure has been considered a difficult to handle and hopeless syndrome. However, in recent years acute heart failure has become a growing area of study and this is the first book to cover extensively the diagnosis and management of this complex condition. The book reflects the considerable amounts of new data reported and many new concepts which have been proposed in the last 3-4 years looking at the epidemiology, diagnostic and treatment of acute heart failure.

Cardiovascular Disorders in Hemodialysis

Cardiovascular Disorders in Hemodialysis PDF Author: Claudio Ronco
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805579381
Category : Medical
Languages : en
Pages : 377

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Book Description
Hemodialysis therapy has become a well-established form of renal replacement, and due to continuous improvements in technology, a series of new biomaterials and techniques for the clinical routine have been developed. Nevertheless, cardiovascular disorders in hemodialysis and uremia represent one of the most important aspects of modern nephrological care. This publication is therefore dedicated to cardiovascular risk factors, the role of the endothelium, problems related to mineral disorders and finally to the possible impact of new technologies on the final outcome in hemodialysis. Being a state-of-the-art appraisal of today's technology and current issues in hemodialysis with special regard to cardiovascular disorders and risk factors, this book is a synthesis between an educational effort aimed at the newer generations of physicians and nurses in the field of hemodialysis and a state-of-the-art description of the most advanced technologies in this field. At the same time, the lessons learned from large international trials, either already completed or to be completed in the years to come, are presented.