Calcium-binding Proteins in Avian and Mammalian Central Nervous System PDF Download
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Author: Katharina Braun
Publisher:
ISBN: 9783437113109
Category : Calcium-binding proteins
Languages : en
Pages : 64
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Book Description
Author: Katharina Braun
Publisher:
ISBN: 9783437113109
Category : Calcium-binding proteins
Languages : en
Pages : 64
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Book Description
Author: Thomas N. Parks
Publisher: Springer Science & Business Media
ISBN: 1475742193
Category : Science
Languages : en
Pages : 336
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Book Description
The auditory system has a remarkable ability to adjust to an ever-changing environment. The six review chapters that comprise Plasticity of the Central Auditory System cover a spectrum of issues concerning this ability to adapt, defined by the widely applicable term "plasticity". With chapters focusing on the development of the cochlear nucleus, the mammalian superior olivary complex, plasticity in binaural hearing, plasticity in the auditory cortex, neural plasticity in bird songs, and plasticity in the insect auditory system, this volume represents much of the most current research in this field. The volume is thorough enough to stand alone, but is closely related a previous SHAR volume, Development of the Auditory System (Volume 9) by Rubel, Popper, and Fay. The book fully addresses the difficulties, challenges, and complexities of this topic as it applies to the auditory development of a wide variety of species.
Author: R. Pochet
Publisher: Springer Science & Business Media
ISBN: 9401006881
Category : Medical
Languages : en
Pages : 746
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Book Description
The enormous and varied role of calcium in living systems is now widely appreciated by both cell biologists and clinicians. The identification and characterisation of new calcium binding proteins and regulatory pathways is matched by the recognition of the involvement of calcium binding proteins in a growing number of disease states. This book is intended to introduce clinicians to fundamental biological research, whilst at the same time attracting researchers to the clinical world. The publication of the book coincides with the elucidation of the complete Human Genomic Sequence. As a result of this, scientists now have access to an unprecedented array of data, from which new calcium binding proteins and hence new regulatory pathways will undoubtedly be discovered. It is a further aim of this book to provide a `key' to open the door to the new postgenomic era. The book is in three parts. The first section introduces the reader to the role of calcium in cell biology, providing an appreciation of how this small, simple, non-metabolisable agent can move rapidly and silently through the different cellular compartments, thereby influencing and controlling the fate of the cell. This section also illustrates and dissects the often-complex interplay between calcium and numerous agents in muscle and endocrine cells, neurons, hepatocytes, and platelets. In the second section the reader will discover the role of calcium and its partners in common diseases such as migraine and drug dependence. New classes of diseases such as annexinopathies, channelopathies, calcium-sensing disorders, and citrullinemia are discussed, and the authors give many new insights into the molecular mechanisms of the diseases, thereby explaining how and why they occur. Such information is clearly of primary importance for the pharmaceutical industry. New ideas and concepts of neurodegenerative diseases are introduced, which should stimulate new approaches. Clinicians will also have access, in a comprehensive and authoritative yet highly readable chapter, to data from recent large-scale clinical studies on the numerous and widely prescribed calcium antagonists. The final section gives information on new methods and devices for calcium imaging, and illustrates how calcium movement and change can be monitored and ingeniously utilised as a fast, cheap, and accurate drug screening instrument.
Author: Hiroshi Kawasaki
Publisher:
ISBN:
Category : Calcium
Languages : en
Pages : 212
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Book Description
Author: VOGT
Publisher: Springer Science & Business Media
ISBN: 1489967044
Category : Science
Languages : en
Pages : 646
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Book Description
Author: Eric Stalberg
Publisher: Springer Science & Business Media
ISBN: 3709164648
Category : Medical
Languages : en
Pages : 520
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Book Description
During the last decades, research on spinal cord has attracted a great deal of attention because of problems such as sensory-motor and autonomic dysfunctions associated with traumatic and other injuries. Recording of spinal cord evoked potentials is one of the most promising approaches to understand the spinal cord function. However, the details of the evoked potentials and their significance in various pathological conditions are not yet fully characterized. This book summarizes new findings in the field of electrophysiology and relates this knowledge to pathology and regeneration research. It is the first one which deals in great detail with various ways to monitor spinal cord function in experimental and clinical situations. It provides an up-to-date knowledge regarding spinal cord bioelectrical activity and its modification with pharmacological agents and covers new aspects of regeneration studies, particularly the role of myelin associated inhibitory molecules. A section is devoted to clinical studies dealing with electrical activity, pathology, and current therapeutic measures. This volume will be useful both to basic and clinical neuroscientists engaged in the field of neurology, neurophysiology, neurochemistry, neurosurgery, neuropathology, and related disciplines in order to understand basic functions of the spinal cord and to stimulate further research in this rapidly advancing field.
Author: Joseph A. Cotruvo
Publisher: Elsevier
ISBN: 0323910858
Category : Science
Languages : en
Pages : 412
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Book Description
Spectrophotometric methods to probe the solution chemistry of lanthanide complexes with macromolecules / Gauthier J.-P. Deblonde -- Determination of affinities of lanthanide-binding proteins using chelator-buffered titrations / Joseph A. Mattocks, Jonathan L. Tirsch, and Joseph A. Cotruvo, Jr. -- Electron paramagnetic resonance of lanthanides / Joseph E. McPeak, Sandra S. Eaton, and Gareth R. Eaton -- Characterization of lanthanoid-binding proteins using NMR spectroscopy / Enrico Ravera, Linda Cerofolini, Marco Fragai, Giacomo Parigi, and Claudio Luchinat -- Macromolecular crystallography for f-element complex characterization / Roger M. Pallares, Korey P. Carter, David Faulkner, and Rebecca J. Abergel -- Infrared spectroscopy probes ion binding geometries / Sean C. Edington, Stephanie Liu, and Carlos R. Baiz -- Predicting lanthanide coordination structures in solution with molecular simulation / David C. Cantu -- Characteristics of Gd(III) spin labels for the study of protein conformations / Angeliki Giannoulis, Yasmin Ben-Ishay, and Daniella Goldfarb - Lanthanide-based resonance energy transfer biosensors for live-cell applications / Ha Pham and Lawrence W. Miller -- 86Y PET imaging / Mariane Le Fur and Peter Caravan -- Aqueous chemistry of the smallest rare earth : Comprehensive characterization of radioactive and non-radioactive scandium complexes for biological applications / Brett A. Vaughn, Angus J. Koller, and Eszter Boros -- In vitro selection and application of lanthanide-dependent DNAzymes / Po-Jung Jimmy Huang and Juewen Liu.
Author: Larry R. Squire
Publisher: Oxford University Press
ISBN: 0195361598
Category : Medical
Languages : en
Pages : 438
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Book Description
This book brings together an internationally respected group of researchers for the purpose of examining neuroplasticity, a topic of immense current interest in psychology, neuroscience, neuropsychology, and clinical neurology. The chapters represent state-of-the-art work on neuroplasticity at all levels: behavioral, neural, and molecular. They describe recent work on memory ranging from cellular morphological studies in invertebrates to research on the human brain made possible by new advances in neuroimaging technology. The book begins with an introductory chapter that considers the psychology of memory at the global, structural level. The remainder of the volume is divided into three related parts. The first focuses on recent approaches, which are based in part on new technology, that aim to measure and describe activity in relatively large populations of neurons. The second focuses on memory at the level of brain systems. One major theme to emerge from work at this level is that memory is composed of multiple, separable components that can be identified with specific anatomical structures and connections. The third part of the book focuses on molecular and cellular studies that show how individual neurons and their synapses behave in a history-dependent manner. This research concerns both brief changes in synaptic plasticity as well as more lasting changes in connectivity, which depend on altered gene expression and morphological growth and change. Altogether, the chapters provide a rich summary of the breadth and excitement of contemporary research on the biology of memory.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1364
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Book Description
Author: Cynthia Petrie Smith
Publisher:
ISBN:
Category : Animal models in research
Languages : en
Pages : 92
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Book Description
