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Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309044901
Category : Medical
Languages : en
Pages : 84
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Book Description
The call for a "parallel track" for AIDS drug developmentâ€"a proposal that would allow the early distribution of AIDS drugs to large numbers of patients in parallel with the conventional clinical trials that assess the drugs' safety and efficacyâ€"has sparked controversy within the scientific community. Questions have arisen about the risks to patients of such a plan, about its potential effect on the successful completion of standard controlled trials, and about whether the parallel track will generate useful data. Larger questions have also been raised about whether the parallel track heralds fundamental changes in the philosophy underlying drug regulation in the United States, about the costs and financing of investigational therapies and associated medical costs, and about the role of expanded access mechanisms for drugs in reaching those whose health care is generally inadequate. This volume summarizes a conference hosted by the Institute of Medicine that illuminated these issues.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309044901
Category : Medical
Languages : en
Pages : 84
Get Book Here
Book Description
The call for a "parallel track" for AIDS drug developmentâ€"a proposal that would allow the early distribution of AIDS drugs to large numbers of patients in parallel with the conventional clinical trials that assess the drugs' safety and efficacyâ€"has sparked controversy within the scientific community. Questions have arisen about the risks to patients of such a plan, about its potential effect on the successful completion of standard controlled trials, and about whether the parallel track will generate useful data. Larger questions have also been raised about whether the parallel track heralds fundamental changes in the philosophy underlying drug regulation in the United States, about the costs and financing of investigational therapies and associated medical costs, and about the role of expanded access mechanisms for drugs in reaching those whose health care is generally inadequate. This volume summarizes a conference hosted by the Institute of Medicine that illuminated these issues.
Author: Kristi Brown-Montesano
Publisher: Univ of California Press
ISBN: 0520385799
Category : Biography & Autobiography
Languages : en
Pages : 344
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Book Description
Is The Marriage of Figaro just about Figaro? Is Don Giovanni’s story the only one—or even the most interesting one—in the opera that bears his name? For generations of critics, historians, and directors, it’s Mozart’s men who have mattered most. Too often, the female characters have been understood from the male protagonist’s point of view or simply reduced on stage (and in print) to paper cutouts from the age of the powdered wig and the tightly cinched corset. It’s time to give Mozart’s women—and Mozart’s multi-dimensional portrayals of feminine character—their due. In this lively book, Kristi Brown-Montesano offers a detailed exploration of the female roles in Mozart’s four most frequently performed operas, Le nozze di Figaro, Don Giovanni, Così fan tutte, and Die Zauberflöte. Each chapter takes a close look at the music, libretto text, literary sources, and historical factors that give shape to a character, re-evaluating common assumptions and proposing fresh interpretations. Brown-Montesano views each character as the subject of a story, not merely the object of a hero’s narrative or the stock figure of convention. From amiable Zerlina, to the awesome Queen of the Night, to calculating Despina, all of Mozart’s women have something unique to say. These readings also tackle provocative social, political, and cultural issues, which are used in the operas to define positive and negative images of femininity: revenge, power, seduction, resistance, autonomy, sacrifice, faithfulness, class, maternity, and sisterhood. Keenly aware of the historical gap between the origins of these works and contemporary culture, Brown-Montesano discusses how attitudes about such concepts—past and current—influence our appreciation of these fascinating representations of women.
Author: Ellen Hartigan-O'Connor
Publisher: Oxford University Press
ISBN: 019090657X
Category : History
Languages : en
Pages : 640
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Book Description
From the first European encounters with Native American women to today's crisis of sexual assault, The Oxford Handbook of American Women's and Gender History boldly interprets the diverse history of women and how ideas about gender shaped their access to political and cultural power in North America. Over twenty-nine chapters, this handbook illustrates how women's and gender history can shape how we view the past, looking at how gender influenced people's lives as they participated in migration, colonialism, trade, warfare, artistic production, and community building. Theoretically cutting edge, each chapter is alive with colorful historical characters, from young Chicanas transforming urban culture, to free women of color forging abolitionist doctrines, Asian migrant women defending the legitimacy of their marriages, and transwomen fleeing incarceration. Together, their lives constitute the history of a continent. Leading scholars across multiple generations demonstrate the power of innovative research to excavate a history hidden in plain sight. Scrutinizing silences in the historical record, from the inattention to enslaved women's opinions to the suppression of Indian women's involvement in border diplomacy, the authors challenge the nature of historical evidence and remap what counts in our interpretation of the past. Together and separately, these essays offer readers a deep understanding of the variety and centrality of women's lives to all dimensions of the American past, even as they show that the boundaries of "women," "American," and "history" have shifted across the centuries.
Author: Kevin Passmore
Publisher: OUP Oxford
ISBN: 0191508551
Category : Political Science
Languages : en
Pages : 185
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Book Description
What is fascism? Is it revolutionary? Or is it reactionary? Can it be both? Fascism is notoriously hard to define. How do we make sense of an ideology that appeals to streetfighters and intellectuals alike? That is overtly macho in style, yet attracts many women? That calls for a return to tradition while maintaining a fascination with technology? And that preaches violence in the name of an ordered society? In the new edition of this Very Short Introduction, Kevin Passmore brilliantly unravels the paradoxes of one of the most important phenomena in the modern world—tracing its origins in the intellectual, political, and social crises of the late nineteenth century, the rise of fascism following World War I, including fascist regimes in Italy and Germany, and the fortunes of 'failed' fascist movements in Eastern Europe, Spain, and the Americas. He also considers fascism in culture, the new interest in transnational research, and the progress of the far right since 2002. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.
Author: Lizabeth A. Allison
Publisher: Wiley
ISBN: 9781118312599
Category : Science
Languages : en
Pages : 0
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Book Description
Unique in in its focus on eukaryotic molecular biology, this textbook provides a distillation of the essential concepts of molecular biology, supported by current examples, experimental evidence, and boxes that address related diseases, methods, and techniques. End-of-chapter analytical questions are well designed and will enable students to apply the information they learned in the chapter. A supplementary website include self-tests for students, resources for instructors, as well as figures and animations for classroom use.
Author:
Publisher:
ISBN:
Category : Canada
Languages : en
Pages : 422
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Book Description
Provides historical coverage of the United States and Canada from prehistory to the present. Includes information abstracted from over 2,000 journals published worldwide.
Author: Georgina Waylen
Publisher: Oxford University Press
ISBN: 0199790833
Category : Social Science
Languages : en
Pages : 887
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Book Description
As a field of scholarship, gender and politics has exploded over the last fifty years and is now global, institutionalized, and ever expanding. The Oxford Handbook of Gender and Politics brings to political science an accessible and comprehensive overview of the key contributions of gender scholars to the study of politics and shows how these contributions produce a richer understanding of polities and societies. Like the field it represents, the handbook has a broad understanding of what counts as political and is based on a notion of gender that highlights masculinities as well as femininities, thereby moving feminist debates in politics beyond the focus on women. It engages with some of the key aspects of political science as well as important themes in gender and feminist research (such as sexuality and body politics), thereby forging a dialogue between gender studies in politics and mainstream political science. The handbook is organized in sections that look at sexuality and body politics; political economy; civil society; participation, representation and policymaking; institutions, states and governance as well as nation, citizenship and identity. The Oxford Handbook of Gender and Politics contains and reflects the best scholarship in its field.
Author: UNESCO
Publisher: UNESCO Publishing
ISBN: 9231004506
Category : Political Science
Languages : en
Pages : 757
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Book Description
Author: Harvey F. Lodish
Publisher: Scientific American Library
ISBN:
Category : Cells
Languages : en
Pages : 1192
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Book Description
With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.
Author: Markus D. Dubber
Publisher: Oxford University Press
ISBN: 0190067411
Category : Law
Languages : en
Pages : 1000
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Book Description
This volume tackles a quickly-evolving field of inquiry, mapping the existing discourse as part of a general attempt to place current developments in historical context; at the same time, breaking new ground in taking on novel subjects and pursuing fresh approaches. The term "A.I." is used to refer to a broad range of phenomena, from machine learning and data mining to artificial general intelligence. The recent advent of more sophisticated AI systems, which function with partial or full autonomy and are capable of tasks which require learning and 'intelligence', presents difficult ethical questions, and has drawn concerns from many quarters about individual and societal welfare, democratic decision-making, moral agency, and the prevention of harm. This work ranges from explorations of normative constraints on specific applications of machine learning algorithms today-in everyday medical practice, for instance-to reflections on the (potential) status of AI as a form of consciousness with attendant rights and duties and, more generally still, on the conceptual terms and frameworks necessarily to understand tasks requiring intelligence, whether "human" or "A.I."
