Boolean Networks as Predictive Models of Emergent Biological Behaviors PDF Download
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Author: Jordan C. Rozum
Publisher: Cambridge University Press
ISBN: 1009292943
Category : Science
Languages : en
Pages : 118
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Book Description
Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions – from molecules in gene regulatory networks to species in ecological networks – and the often-incomplete state of system knowledge, such as the unknown values of kinetic parameters for biochemical reactions. Boolean networks have emerged as a powerful tool for modeling these systems. This Element provides a methodological overview of Boolean network models of biological systems. After a brief introduction, the authors describe the process of building, analyzing, and validating a Boolean model. They then present the use of the model to make predictions about the system's response to perturbations and about how to control its behavior. The Element emphasizes the interplay between structural and dynamical properties of Boolean networks and illustrates them in three case studies from disparate levels of biological organization.
Author: Jordan C. Rozum
Publisher: Cambridge University Press
ISBN: 1009292943
Category : Science
Languages : en
Pages : 118
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Book Description
Interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions – from molecules in gene regulatory networks to species in ecological networks – and the often-incomplete state of system knowledge, such as the unknown values of kinetic parameters for biochemical reactions. Boolean networks have emerged as a powerful tool for modeling these systems. This Element provides a methodological overview of Boolean network models of biological systems. After a brief introduction, the authors describe the process of building, analyzing, and validating a Boolean model. They then present the use of the model to make predictions about the system's response to perturbations and about how to control its behavior. The Element emphasizes the interplay between structural and dynamical properties of Boolean networks and illustrates them in three case studies from disparate levels of biological organization.
Author: Jordan C. Rozum
Publisher: Cambridge University Press
ISBN: 9781009292962
Category : Science
Languages : en
Pages : 0
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Book Description
This Element shows interacting biological systems at all organizational levels display emergent behavior. Modeling these systems is made challenging by the number and variety of biological components and interactions and the often-incomplete state of system knowledge. Boolean networks have emerged as a powerful tool for modeling these systems. The authors provide a methodological overview of Boolean network models of biological systems. After a brief introduction, they describe the process of building, analyzing, and validating a Boolean model. The authors then present the use of the model to make predictions about the system's response to perturbations and about how to control its behavior. The Element emphasizes the interplay between structural and dynamical properties of Boolean networks and illustrates them in three case studies from disparate levels of biological organization.
Author:
Publisher: Elsevier
ISBN: 0444640479
Category : Science
Languages : en
Pages : 4876
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Book Description
Comprehensive Biotechnology, Third Edition, Six Volume Set unifies, in a single source, a huge amount of information in this growing field. The book covers scientific fundamentals, along with engineering considerations and applications in industry, agriculture, medicine, the environment and socio-economics, including the related government regulatory overviews. This new edition builds on the solid basis provided by previous editions, incorporating all recent advances in the field since the second edition was published in 2011. Offers researchers a one-stop shop for information on the subject of biotechnology Provides in-depth treatment of relevant topics from recognized authorities, including the contributions of a Nobel laureate Presents the perspective of researchers in different fields, such as biochemistry, agriculture, engineering, biomedicine and environmental science
Author: Adriana Compagnoni
Publisher: Springer
ISBN: 3030242021
Category : Computers
Languages : en
Pages : 219
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Book Description
This book constitutes the refereed conference proceedings of the 11th International Conference on Bio-Inspired Information and Communications Technologies, held in Pittsburgh, PA, USA, in March 2019. The 13 revised full papers and 2 short papers were selected from 29 submissions. Past iterations of the conference have attracted contributions in Direct Bioinspiration (physical biological materials and systems used within technology) as well as Indirect Bioinspiration (biological principles, processes and mechanisms used within the design and application of technology). This year, the scope has expanded to include a third thrust: Foundational Bioinspiration (bioinspired aspects of game theory, evolution, information theory, and philosophy of science).
Author: Ignacio Rojas
Publisher: Springer Nature
ISBN: 3031646363
Category : Bioinformatics
Languages : en
Pages : 387
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Book Description
Zusammenfassung: This volume constitutes the proceedings of the 11th International Work-Conference on IWBBIO 2023, held in Meloneras, Gran Canaria, Spain, during July 15-17, 2022. The 54 full papers were carefully reviewed and selected from 148 submissions. They were organized in the following topical sections: Healthcare and Diseases, Machine Learning in Bioinformatics, New Advances in Deep Learning in Bioinformatics and Biomedicine, Novel Methodologies and Applications in Bioinformatics and Biomedicine
Author: Terry Bossomaier
Publisher: Springer
ISBN: 3319432222
Category : Computers
Languages : en
Pages : 210
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Book Description
This book considers a relatively new metric in complex systems, transfer entropy, derived from a series of measurements, usually a time series. After a qualitative introduction and a chapter that explains the key ideas from statistics required to understand the text, the authors then present information theory and transfer entropy in depth. A key feature of the approach is the authors' work to show the relationship between information flow and complexity. The later chapters demonstrate information transfer in canonical systems, and applications, for example in neuroscience and in finance. The book will be of value to advanced undergraduate and graduate students and researchers in the areas of computer science, neuroscience, physics, and engineering.
Author: Giulio Cimini
Publisher: Cambridge University Press
ISBN: 110880876X
Category : Science
Languages : en
Pages : 106
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Book Description
Complex networks datasets often come with the problem of missing information: interactions data that have not been measured or discovered, may be affected by errors, or are simply hidden because of privacy issues. This Element provides an overview of the ideas, methods and techniques to deal with this problem and that together define the field of network reconstruction. Given the extent of the subject, the authors focus on the inference methods rooted in statistical physics and information theory. The discussion is organized according to the different scales of the reconstruction task, that is, whether the goal is to reconstruct the macroscopic structure of the network, to infer its mesoscale properties, or to predict the individual microscopic connections.
Author: Yves Crama
Publisher: Cambridge University Press
ISBN: 1139498630
Category : Mathematics
Languages : en
Pages : 711
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Book Description
Written by prominent experts in the field, this monograph provides the first comprehensive, unified presentation of the structural, algorithmic and applied aspects of the theory of Boolean functions. The book focuses on algebraic representations of Boolean functions, especially disjunctive and conjunctive normal form representations. This framework looks at the fundamental elements of the theory (Boolean equations and satisfiability problems, prime implicants and associated short representations, dualization), an in-depth study of special classes of Boolean functions (quadratic, Horn, shellable, regular, threshold, read-once functions and their characterization by functional equations) and two fruitful generalizations of the concept of Boolean functions (partially defined functions and pseudo-Boolean functions). Several topics are presented here in book form for the first time. Because of the depth and breadth and its emphasis on algorithms and applications, this monograph will have special appeal for researchers and graduate students in discrete mathematics, operations research, computer science, engineering and economics.
Author: Phil Husbands
Publisher: MIT Press
ISBN: 9780262581578
Category : Computers
Languages : en
Pages : 608
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Book Description
Topics include self-organization, the origins of life, natural selection, evolutionary computation, neural networks, communication, artificial worlds, software agents, philosophical issues in artificial life, ethical problems, and learning and development. Researchers in artificial life attempt to use the physical representation of lifelike phenomena to understand the organizational principles underlying the dynamics of living systems. The goal of the 1997 European Conference on Artificial Life is to provoke new understandings of the relationships between the natural and the artificial. Topics include self-organization, the origins of life, natural selection, evolutionary computation, neural networks, communication, artificial worlds, software agents, philosophical issues in artificial life, ethical problems, and learning and development.
Author: Hugues Bersini
Publisher: Springer Science & Business Media
ISBN: 3540377492
Category : Computers
Languages : en
Pages : 471
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Book Description
This book constitutes the refereed proceedings of the 5th International Conference on Artificial Immune Systems, ICARIS 2006. The book presents 34 revised full papers, are organized in topical sections on computer simulation of classical immunology, computer simulation of idiotypic network, immunoinformatics conceptual papers, pattern recognition type of application, optimization type of application, control and time-series type of application, danger theory inspired application, and text mining application.
