Bone Aging and Osteoporosis: Recent Evidence Focusing on Plant-Based Natural Products

Bone Aging and Osteoporosis: Recent Evidence Focusing on Plant-Based Natural Products PDF Author: Lingfeng Zeng
Publisher: Frontiers Media SA
ISBN: 2832545955
Category : Medical
Languages : en
Pages : 170

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Book Description
The human skeleton undergoes a life-long remodeling process. Bone homeostasis requires a potential balance between bone-resorbing osteoclasts and bone-forming osteoblasts. With old age, bone homeostasis undergoes deregulation, and normal bone remodeling could not make bone mass stable, thus causing osteopenia and osteoporosis. Osteoporosis is a systemic bone disease characterized by reduced bone mass, degraded bone microstructure, increased bone fragility and raised risk of fracture. Osteoporosis is a frequently occurring and common disease in the aging population, especially in postmenopausal women and elderly men. The updated research found that one-third of women aged 60 to 70 suffer from osteoporosis; Two-thirds of women aged 80 years or older have osteoporosis. About 20-25% of women over 50 years of age have one or more vertebral fractures. Recent research evidence indicates that an increasing number of plant-based natural products (or secondary metabolites), such as polyunsaturated fatty acids, phytosterols, flavonoids, and other botanicals active compounds, have beneficial effects on the risk of osteoporosis. Compared with conventional therapies, plant-based natural products with thousands of years of medical use experience are gradually approved for clinical use due to fewer adverse reactions, low toxicity, high efficiency and good tolerance. Natural products have been an important source of inspiration for new drug development. However, most of the evidence regarding the anti-osteoporosis effects of natural products comes from in vitro and preclinical in vivo studies, and only a few natural products have been used clinically. All of these above-mentioned still require rigorously designed studies and further verification.

Bone Aging and Osteoporosis: Recent Evidence Focusing on Plant-Based Natural Products

Bone Aging and Osteoporosis: Recent Evidence Focusing on Plant-Based Natural Products PDF Author: Lingfeng Zeng
Publisher: Frontiers Media SA
ISBN: 2832545955
Category : Medical
Languages : en
Pages : 170

Get Book Here

Book Description
The human skeleton undergoes a life-long remodeling process. Bone homeostasis requires a potential balance between bone-resorbing osteoclasts and bone-forming osteoblasts. With old age, bone homeostasis undergoes deregulation, and normal bone remodeling could not make bone mass stable, thus causing osteopenia and osteoporosis. Osteoporosis is a systemic bone disease characterized by reduced bone mass, degraded bone microstructure, increased bone fragility and raised risk of fracture. Osteoporosis is a frequently occurring and common disease in the aging population, especially in postmenopausal women and elderly men. The updated research found that one-third of women aged 60 to 70 suffer from osteoporosis; Two-thirds of women aged 80 years or older have osteoporosis. About 20-25% of women over 50 years of age have one or more vertebral fractures. Recent research evidence indicates that an increasing number of plant-based natural products (or secondary metabolites), such as polyunsaturated fatty acids, phytosterols, flavonoids, and other botanicals active compounds, have beneficial effects on the risk of osteoporosis. Compared with conventional therapies, plant-based natural products with thousands of years of medical use experience are gradually approved for clinical use due to fewer adverse reactions, low toxicity, high efficiency and good tolerance. Natural products have been an important source of inspiration for new drug development. However, most of the evidence regarding the anti-osteoporosis effects of natural products comes from in vitro and preclinical in vivo studies, and only a few natural products have been used clinically. All of these above-mentioned still require rigorously designed studies and further verification.

Nutrition and Osteoporosis

Nutrition and Osteoporosis PDF Author: Harold H. Draper
Publisher: Springer Science & Business Media
ISBN: 1475790929
Category : Technology & Engineering
Languages : en
Pages : 325

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Book Description
Nutrition and Osteoporosis: Seeing Through a Glass, Darkly (1 Cor. 13:12) This volume of Advances in Nutritional Research deals with the present state of knowledge relative to the role of nutrition in the etiology of osteoporosis, one of the most serious degenerative diseases in the aging population. As a back drop for subsequent chapters on specific nutrients, Chapter 1 provides a com prehensive account of the gain and loss of bone throughout the life cycle, with emphasis on the architectural changes in later life that predispose to osteoporotic bone fractures. Chapter 2 documents the occurrence of aging bone loss through out human archeological history and Chapter 3 extends this documentation to all non-human vertebrate species so far examined, including primates living in the wild. It is apparent that a progressive loss of bone tissue is a normal accompaniment of aging among higher vertebrates. Whether it is a cause of bone fractures in animals, as it is in humans, is still unknown. It has also been established that there are significant differences in the frequency of osteoporotic fractures among human families, ethnic groups, national populations and diet cultures. Numerous studies have been carried out in an effort to explain these differences, and many of these deal with the possible effect of nutrition. Protracted controversies over the role of nutrition in the etiology of osteoporosis are reflected in the contents of several of the ensuing chapters.

Plant Bioactives as Natural Panacea against Age-Induced Diseases

Plant Bioactives as Natural Panacea against Age-Induced Diseases PDF Author: Kanti Bhooshan Pandey
Publisher: Elsevier
ISBN: 0323913296
Category : Science
Languages : en
Pages : 500

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Book Description
Plant Bioactives as Natural Panacea Against Age-induced Diseases: Nutraceuticals and Functional Lead Compounds for Drug Development presents comprehensive information on the complications of aging and the bioactive phytochemicals that in specific herbal formulations, including beverages, can mitigate them. The book extensively describes the current information on the role of plant bioactive components in delaying or preventing the aging process and associated complications, while also covering different strategies and scientific evidence of possible synergistic effects of these studies, enabling the formulation of more effective natural drugs to intervene in aging and associated events. Chapters cover the broad areas of plant bioactive compounds in promoting healthy aging and longevity, including balancing glucose homeostasis, in cognitive impairments, age-related diseases, food trends and the anti-aging diet in Asia and other regions, as well as the social and economic impact of dietary patterns in aging interventions. Written by a team of global experts. - Describes plant bioactives for specific age disorders - Focuses on the discovery of new herbal origin drugs and potential druggable targets for the treatment of chronic diseases of world importance - Includes cutting-edge research information on cell senescence during aging and assesses the plant bioactive compounds

Interdisciplinary Nutritional Management and Care for Older Adults

Interdisciplinary Nutritional Management and Care for Older Adults PDF Author: Ólöf G. Geirsdóttir
Publisher: Springer Nature
ISBN: 3030638928
Category : Adulthood
Languages : en
Pages : 274

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Book Description
Intro -- Foreword -- Acknowledgements -- Contents -- Part I: Nutritional Care in Geriatrics -- 1: Overview of Nutrition Care in Geriatrics and Orthogeriatrics -- 1.1 Defining Malnutrition -- 1.2 Nutrition Care in Older Adults: A Complex and Necessary Challenge -- 1.3 Malnutrition: A Truly Wicked Problem -- 1.4 Building the Rationale for Integrated Nutrition Care -- 1.5 Managing the Wicked Nutrition Problems with a SIMPLE Approach (or Other Tailored Models) -- 1.5.1 Keep It SIMPLE When Appropriate -- 1.5.2 A SIMPLE Case Example -- 1.5.2.1 S-Screen for Malnutrition -- 1.5.2.2 I-Interdisciplinary Assessment -- 1.5.2.3 M-Make the Diagnosis (es) -- 1.5.2.4 P-Plan with the Older Adult -- 1.5.2.5 L-Implement Interventions -- 1.5.2.6 E-Evaluate Ongoing Care Requirements -- 1.6 Bringing It All Together: Integrated Nutrition Care Across the Four Pillars of (Ortho) Geriatric Care -- 1.7 Summary: Finishing Off with a List of New Questions -- References -- Recommended Reading -- 2: Nutritional Requirements in Geriatrics -- 2.1 Nutritional Recommendations for Older Adults, Geriatric and Orthogeriatric Patients -- 2.2 Nutritional Recommendations for Older Adults -- 2.2.1 Energy Requirement and Recommended Intake -- 2.2.2 Protein Requirement and Recommended Intake -- 2.2.3 Micronutrients and Dietary Fibers -- 2.3 Nutritional Risk Factors in Older Adults -- 2.4 Estimating Intake in Older Adults -- 2.5 Nutritional Status of Older Adults, Geriatric and Orthogeriatric Patients -- 2.6 Summary -- References -- Recommended Reading -- 3: Nutritional Assessment, Diagnosis, and Treatment in Geriatrics -- 3.1 The Nutrition Care Process -- 3.2 Nutritional Screening/Risk Detection -- 3.3 Nutritional Assessment and Diagnosis -- 3.3.1 Nutrition Impact Symptoms -- 3.3.2 Nutritional Diagnosis -- 3.3.3 Etiologic Criteria.

Physical Activity and Bone Health

Physical Activity and Bone Health PDF Author: Karim Khan
Publisher: Human Kinetics
ISBN: 9780880119689
Category : Medical
Languages : en
Pages : 296

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Book Description
With an emphasis on exercise and its effect on bone, this text includes sections on basic anatomy and the physiology of the structure and function of bone as well as exercises to maintain a healthy skeleton through to old age.

The Healthy Bones Nutrition Plan and Cookbook

The Healthy Bones Nutrition Plan and Cookbook PDF Author: Laura Kelly
Publisher: Chelsea Green Publishing
ISBN: 1603586245
Category : Cooking
Languages : en
Pages : 321

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Book Description
"Calcium helps build strong bones, buts it's a myth that taking a daily calcium supplement will enable you to avoid potentially debilitating bone loss. Building bone requires a full complement of minerals and vitamins that too often are lacking in a woman's--or man's--diet in the quantity and combination required to prevent and treat osteoporosis. In this book, Dr. Laura Kelly and Helen Bryman Kelly provide scientifically sound guidance on how to monitor your nutrient intake and cook right for bone health to avoid deficiencies of the key players in bone metabolism--including calcium, magnesium, Vitamin D, and Vitamin K2--and, in many cases, to avoid the use of osteoporosis drugs. Follow their instructions for creating your own personal nutrition plan and enjoy delicious bone-healthy meals from a selection of more than 100 recipes ranging from sauces and small plates to soups, salads, main dishes, and more,"--page [4] of cover.

Nutrition and Bone Health

Nutrition and Bone Health PDF Author: Michael F. Holick
Publisher: Springer
ISBN: 1493920014
Category : Medical
Languages : en
Pages : 737

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Book Description
This newly revised edition contains updated versions of all of the topics that were in the first edition and has been substantially expanded with an additional 5 chapters. Each chapter includes information from the most up-to-date research on how nutritional factors can affect bone health, written with an evidence-based focus and complete with comprehensive references for each subject. Nutrition and Bone Health, second edition covers all aspects of nutrition and the skeleton, from the history and fundamentals, to the effects of macronutrients, minerals, vitamins, and supplements, and even covers the effects of lifestyle, the different life stages, and nutrition-related disorders and secondary osteoporosis. New chapters include HIV & AIDs and the skeleton, celiac disease and bone health, and nutrition and bone health in space. Nutrition and Bone Health, second edition is a necessary resource for health care professionals, medical students, graduate students, dietitians, and nutritionists who are interested in how nutrition affects bone health during all stages of life.

Building Bone Vitality: A Revolutionary Diet Plan to Prevent Bone Loss and Reverse Osteoporosis--Without Dairy Foods, Calcium, Estrogen, or Drugs

Building Bone Vitality: A Revolutionary Diet Plan to Prevent Bone Loss and Reverse Osteoporosis--Without Dairy Foods, Calcium, Estrogen, or Drugs PDF Author: Amy J. Lanou
Publisher: McGraw Hill Professional
ISBN: 0071600205
Category : Health & Fitness
Languages : en
Pages : 257

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Book Description
Calcium pills don't work. Dairy products don't strengthen bones. Drugs may be dangerous. For years, doctors have been telling us to drink milk, eat dairy products, andtake calcium pills to improve our bone vitality. The problem is, they’re wrong.This groundbreaking guide uses the latest clinical studies and the most upto-date medical information to help you strengthen your bones, reduce therisk of fractures, and prevent osteoporosis. You’ll learn why there’s no proof ofcalcium’s effectiveness, despite what doctors say, and why a low-acid diet isthe only effective way to prevent bone loss. "This clear, convincing explanation of osteoporosis will change the way the world thinks about bone health. Lanou and Castleman prove beyond doubt that milk and dairy are the problem, not the solution." -Rory Freedman, coauthor of #1 New York Times best seller Skinny Bitch "The authors have tackled an almost intractable myth: that calcium is the one and only key to bone vitality. It isn't. Everyone who cares about preventing osteoporosis should read this book." -- Dr. T. Colin Campbell, author of The China Study

How Not to Die

How Not to Die PDF Author: Michael Greger, M.D., FACLM
Publisher: Flatiron Books
ISBN: 1250066123
Category : Health & Fitness
Languages : en
Pages : 577

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Book Description
New York Times Bestseller “This book may help those who are susceptible to illnesses that can be prevented.”—His Holiness the Dalai Lama “Absolutely the best book I’ve read on nutrition and diet” –Dan Buettner, author of The Blue Zones Solution From the physician behind the wildly popular NutritionFacts website, How Not to Die reveals the groundbreaking scientific evidence behind the only diet that can prevent and reverse many of the causes of disease-related death. The vast majority of premature deaths can be prevented through simple changes in diet and lifestyle. In How Not to Die, Dr. Michael Greger, the internationally-renowned nutrition expert, physician, and founder of NutritionFacts.org, examines the fifteen top causes of premature death in America-heart disease, various cancers, diabetes, Parkinson's, high blood pressure, and more-and explains how nutritional and lifestyle interventions can sometimes trump prescription pills and other pharmaceutical and surgical approaches, freeing us to live healthier lives. The simple truth is that most doctors are good at treating acute illnesses but bad at preventing chronic disease. The fifteen leading causes of death claim the lives of 1.6 million Americans annually. This doesn't have to be the case. By following Dr. Greger's advice, all of it backed up by strong scientific evidence, you will learn which foods to eat and which lifestyle changes to make to live longer. History of prostate cancer in your family? Put down that glass of milk and add flaxseed to your diet whenever you can. Have high blood pressure? Hibiscus tea can work better than a leading hypertensive drug-and without the side effects. Fighting off liver disease? Drinking coffee can reduce liver inflammation. Battling breast cancer? Consuming soy is associated with prolonged survival. Worried about heart disease (the number 1 killer in the United States)? Switch to a whole-food, plant-based diet, which has been repeatedly shown not just to prevent the disease but often stop it in its tracks. In addition to showing what to eat to help treat the top fifteen causes of death, How Not to Die includes Dr. Greger's Daily Dozen -a checklist of the twelve foods we should consume every day.Full of practical, actionable advice and surprising, cutting edge nutritional science, these doctor's orders are just what we need to live longer, healthier lives.

Health and Beauty from the Rainforest

Health and Beauty from the Rainforest PDF Author: Gerard Bodeker
Publisher: Biotropics Ramuan
ISBN: 9789814217910
Category : Health & Fitness
Languages : en
Pages : 264

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Book Description
Health and Beauty from the Rainforest will reveal Malaysian health and beauty traditions, founded upon the country's immense wealth of bio-resources. Malaysia's rainforests are among the oldest in the world, and within them Malaysia's peoples have discove