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Author: Mauro Bologna
Publisher: Springer Science & Business Media
ISBN: 161779614X
Category : Medical
Languages : en
Pages : 572
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Book Description
Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.
Author: Mauro Bologna
Publisher: Springer Science & Business Media
ISBN: 161779614X
Category : Medical
Languages : en
Pages : 572
Get Book
Book Description
Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.
Author: Sabyasachi Maiti
Publisher: CRC Press
ISBN: 1315353075
Category : Medical
Languages : en
Pages : 432
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Book Description
The advances in drug delivery systems over recent years have resulted in a large number of novel delivery systems with the potential to revolutionize the treatment and prevention of diseases. Bio-Targets and Drug Delivery Approaches is an easy-to-read book for students, researchers and pharmaceutical scientists providing a comprehensive introduction to the principles of advanced drug delivery and targeting their current applications and potential future developments.
Author: S.E. Monaco
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318023965
Category : Medical
Languages : en
Pages : 147
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Book Description
This high-yield reference book focuses on the clinical, technical, and pathological aspects of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Its reviews cover all aspects of EBUS-TBNA, including the clinical perspective, technical aspects of the procedure, and cytomorphology of common and uncommon entities, as well as highlights diagnostic challenges. Each chapter features a multitude of full-color high-resolution images and includes key references to the current literature in the field. Additionally, reference tables and informative figures highlight the salient points. The book is unique in that it is written by experienced thoracic surgeons, pulmonary medicine physicians, and cytopathologists who use EBUS-TBNA in a large medical center. This publication is of interest to individuals learning and practicing cytopathology, in addition to clinicians practicing pulmonary/thoracic medicine or surgery. In short, it provides important pearls of wisdom to create a comprehensive reference for all physicians involved with EBUS-TBNA.
Author: Scott M. Berry
Publisher: CRC Press
ISBN: 1439825513
Category : Mathematics
Languages : en
Pages : 316
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Book Description
Already popular in the analysis of medical device trials, adaptive Bayesian designs are increasingly being used in drug development for a wide variety of diseases and conditions, from Alzheimer's disease and multiple sclerosis to obesity, diabetes, hepatitis C, and HIV. Written by leading pioneers of Bayesian clinical trial designs, Bayesian Adapti
Author: Kerry S. Courneya
Publisher: Springer Science & Business Media
ISBN: 3642042317
Category : Medical
Languages : en
Pages : 389
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Book Description
This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.
Author: Pedro T. Ramirez
Publisher: Elsevier Health Sciences
ISBN: 032393563X
Category : Medical
Languages : en
Pages : 1311
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Book Description
Written and edited by global leaders in the field, Principles of Gynecologic Oncology Surgery, 2nd Edition, offers a practical, "how-to" approach to the most important and commonly performed procedures in this fast-moving specialty. Organized by cancer type, this comprehensive reference covers issues related to surgical anatomy, patient evaluation, procedure indications and details, and management of complications for both open and minimally invasive procedures. It clearly describes the critical steps for each procedure, provides up-to-date information on the recent literature, and includes high-quality illustrations of anatomy and technique. Covers the most current treatment and management options with expert guidance from leading surgeons at top cancer centers throughout the world. Contains new chapters on surgery in pregnant women who have been diagnosed with gynecologic cancers; perioperative analgesic management; uterine transposition; and uterine transplantation. Provides increased coverage of AI and its use in navigation of surgery; a new section on thoracic cavity and chest wall anatomy; significant updates regarding Enhanced Recovery After Surgery (ERAS); and an expanded discussion of radiation-related complications and their management. Addresses the diagnosis, management and prevention of surgical complications. Provides timely updates on newly recommended sentinel lymph node mapping for endometrial cancer staging, PARP inhibitors in ovarian cancer, molecular subtyping in endometrial cancer, cervical cancer and standard of care. and updates on both laparoscopic and robotic surgery. Includes expert coverage of reconstructive surgery, colorectal surgery, urology, and vascular surgery, each written by surgeon leaders in that particular field. Features procedural videos that guide you through a multitude of procedures, including abdominal exploration using laparoscopy for evaluation of cytoreduction in advanced ovarian cancer, laparoscopic hysterectomies with sentinel lymph node mapping, radical hysterectomy, robotic radical trachelectomy, and more, as well as high-quality illustrations including surgical photos, pathology photos, imaging, and anatomical figures. Any additional digital ancillary content may publish up to 6 weeks following the publication date. · Hyper-CVAD chemotherapy as an option for certain, more aggressive cancers· Coverage on newly recommended sentinel lymph node mapping for endometrial cancer staging· Advancements on cervical cancer and standard of care· Increased coverage of AI and its use in navigatin of surgery
Author: Valeria Barresi
Publisher:
ISBN: 9783036529233
Category :
Languages : en
Pages : 284
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Book Description
Colorectal cancer is one of the most common malignancies worldwide, and the pathogenesis of this neoplasm is probably one of the most studied. The knowledge obtained over time has led to the development of screening and early diagnosis systems, allowing a significant reduction in the incidence of this neoplasm. However, what is currently known probably represents only the tip of the iceberg of the biology of this tumor. It was recently shown that the gut microbiota may contribute to colorectal cancerogenesis. In addition, several novel targeted therapies are now applied to patients with colorectal carcinoma. Nonetheless, several questions are still unanswered. Could the modulation of the gut microbiota modify the risk of tumor progression or the efficacy of therapies? Are there any predictive biomarkers of the risk of tumor progression or the efficacy of target therapies? Is metastatic colorectal cancer one or more diseases? This book collects a series of scientific articles reflecting part of the state of the art regarding colorectal cancer, seeking to answer these questions.
Author: Eric T. Wong
Publisher: Springer
ISBN: 331930576X
Category : Medical
Languages : en
Pages : 129
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Book Description
This concise text provides a complete overview of alternating electric fields therapy -- also known as tumor treating fields -- for glioblastoma and other types of solid tumor malignancies. Readers are given a fundamental understanding of this novel anti-cancer treatment modality by learning from clinical trial data as well as the physical and cell biology effects on tumor cells when alternating electric fields are applied both in vitro and in vivo. Chapters illustrate the physics behind electric field propagation in space and other media. This is followed by a review of our current understanding of the electric field effects on dividing cells - including the disruption of cytokinesis, proper chromosome segregation and activation on the cell surface chaperons that induce immunogenic cell death. Data from phase III trials for the treatment of recurrent and newly diagnosed glioblastomas are included, as well as some of the ancillary post hoc analyses that were performed by various investigators. The remainder of the chapter covers other solid tumor malignancies, including non-small cell lung cancer, pancreatic cancer and ovarian cancer, as this treatment modality is being applied to systemic malignancies. Alternating Electric Fields Therapy in Oncology offers oncologists, neurologists, radiation oncologists, biomedical engineers, cell biologists and mitosis researchers the fundamentals needed for clinical practice.
Author: Harri Vainio
Publisher: IARC
ISBN: 9789283230069
Category : Health & Fitness
Languages : en
Pages : 346
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Book Description
Avoiding overweight and obesity is the best-established diet-related risk factor for cancer. The proportion of people who are overweight/obese is increasing, and the amount of physical activity is decreasing in most populations, including urban populations in many developing countries. The increasing prevalence of overweight/obesity is presumably due to the increasing availability of highly palatable, high-energy foods, and an increasing sedentary lifestyle due to mechanisation of both workplace and leisure activities. Overweight/obesity and reduced physical activity increases the risk of cancers in various organs. Maintaining a healthy body weight and regular physical activity is the second most important way to prevent cancer, after tobacco control. The suggestions of possible public health actions to tackle these risk factors include the promotion of balanced diets, which are not excessive in energy, and broad education and planning to enable and encourage physical activity during work and leisure. Recommendations and a full discussion of these topics are included in the sixth volume in this series of Handbooks.
Author: Neil K. Aaronson
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 328
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Book Description
