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Author: Mohammad Ashrafuzzaman
Publisher: CRC Press
ISBN: 1000451593
Category : Science
Languages : en
Pages : 318
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Book Description
This book provides a comprehensive review of the biophysics and nanotechnology of ion channels. It details the biological and physiological entities of ion channels in cells and addresses various physical perspectives of ion channel structures and functions. Naturally inbuilt and artificial applicable nanotechnologies of ion channels are modelled and explored. It discusses various methods that can be utilized toward understanding ion channel-based cellular diseases. Physical, biochemical, biomedical, and bioinformatics techniques are taken into consideration to enable the development of strategies to address therapeutic drug discovery and delivery. This book will be of interest to advanced undergraduate and graduate students in biophysics and related biomedical sciences in addition to researchers in the field and industry. Features: Provides a stimulating introduction to the structures and functions of ion channels of biological cell membranes and discusses the biophysics of ion channels in condensed matter state and physiological condition Addresses natural processes and nanotechnology opportunities for their purposeful manipulation Lays the groundwork for vitally important medical advances Mohammad Ashrafuzzaman, a biophysicist and condensed matter scientist, is passionate about investigating biological and biochemical processes utilizing the principles and techniques of physics. He is an associate professor at King Saud University’s Biochemistry Department of College of Science, Riyadh, Saudi Arabia, the co-founder of MDT Canada Inc., and the founder of Child Life Development Institute, Edmonton, Canada. He also authored Nanoscale Biophysics of the Cell and Membrane Biophysics.
Author: Mohammad Ashrafuzzaman
Publisher: CRC Press
ISBN: 1000451593
Category : Science
Languages : en
Pages : 318
Get Book Here
Book Description
This book provides a comprehensive review of the biophysics and nanotechnology of ion channels. It details the biological and physiological entities of ion channels in cells and addresses various physical perspectives of ion channel structures and functions. Naturally inbuilt and artificial applicable nanotechnologies of ion channels are modelled and explored. It discusses various methods that can be utilized toward understanding ion channel-based cellular diseases. Physical, biochemical, biomedical, and bioinformatics techniques are taken into consideration to enable the development of strategies to address therapeutic drug discovery and delivery. This book will be of interest to advanced undergraduate and graduate students in biophysics and related biomedical sciences in addition to researchers in the field and industry. Features: Provides a stimulating introduction to the structures and functions of ion channels of biological cell membranes and discusses the biophysics of ion channels in condensed matter state and physiological condition Addresses natural processes and nanotechnology opportunities for their purposeful manipulation Lays the groundwork for vitally important medical advances Mohammad Ashrafuzzaman, a biophysicist and condensed matter scientist, is passionate about investigating biological and biochemical processes utilizing the principles and techniques of physics. He is an associate professor at King Saud University’s Biochemistry Department of College of Science, Riyadh, Saudi Arabia, the co-founder of MDT Canada Inc., and the founder of Child Life Development Institute, Edmonton, Canada. He also authored Nanoscale Biophysics of the Cell and Membrane Biophysics.
Author: Mohammad Ashrafuzzaman
Publisher: Springer Science & Business Media
ISBN: 3642161057
Category : Science
Languages : en
Pages : 190
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Book Description
Physics, mathematics and chemistry all play a vital role in understanding the true nature and functioning of biological membranes, key elements of living processes. Besides simple spectroscopic observations and electrical measurements of membranes we address in this book the phenomena of coexistence and independent existence of different membrane components using various theoretical approaches. This treatment will be helpful for readers who want to understand biological processes by applying both simple observations and fundamental scientific analysis. It provides a deep understanding of the causes and effects of processes inside membranes, and will thus eventually open new doors for high-level pharmaceutical approaches towards fighting membrane- and cell-related diseases.
Author: Richard M. Epand
Publisher: Springer
ISBN: 9811062447
Category : Science
Languages : en
Pages : 224
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Book Description
This volume focuses on the modulation of biological membranes by specific biophysical properties. The readers are introduced to emerging biophysical approaches that mimick specific states (like membrane lipid asymmetry, membrane curvature, lipid flip-flop, lipid phase separation) that are relevant to the functioning of biological membranes. The first chapter describes innovative methods to mimic the prevailing asymmetry in biological membranes by forming asymmetrical membranes made of monolayers with different compositions. One of the chapters illustrates how physical parameters, like curvature and elasticity, can affect and modulate the interactions between lipids and proteins. This volume also describes the sensitivity of certain ion channels to mechanical forces and it presents an analysis of how cell shape is determined by both the cytoskeleton and the lipid domains in the membrane. The last chapter provides evidence that liposomes can be used as a minimal cellular model to reconstitute processes related to the origin of life. Each topic covered in this volume is presented by leading experts in the field who are able to present clear, authoritative and up-to-date reviews. The novelty of the methods proposed and their potential for a deeper molecular description of membrane functioning are particularly relevant experts in the areas of biochemistry, biophysics and cell biology, while also presenting clear and thorough introductions, making the material suitable for students in these fields as well.
Author: Mohammad Ashrafuzzaman
Publisher: CRC Press
ISBN: 1003821642
Category : Science
Languages : en
Pages : 603
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Book Description
This textbook provides an introduction to the fundamental and applied aspects of biophysics for advanced undergraduate and graduate students of physics, chemistry, and biology. The application of physics principles and techniques in exploring biological systems has long been a tradition in scientific research. Biological systems hold naturally inbuilt physical principles and processes which are popularly explored. Systematic discoveries help us understand the structures and functions of individual biomolecules, biomolecular systems, cells, organelles, tissues, and even the physiological systems of animals and plants. Utilizing a physics- based scientific understanding of biological systems to explore disease is at the forefront of applied scientific research. This textbook covers key breakthroughs in biophysics whilst looking ahead to future horizons and directions of research. It contains models based on both classical and quantum mechanical treatments of biological systems. It explores diseases related to physical alterations in biomolecular structures and organizations alongside drug discovery strategies. It also discusses the cutting- edge applications of nanotechnologies in manipulating nanoprocesses in biological systems. Key Features: • Presents an accessible introduction to how physics principles and techniques can be used to understand biological and biochemical systems. • Addresses natural processes, mutations, and their purposeful manipulation. • Lays the groundwork for vitally important natural scientific, technological, and medical advances. Mohammad Ashrafuzzaman, a biophysicist and condensed matter scientist, is passionate about investigating biological and biochemical processes utilizing physics principles and techniques. He is a professor of biophysics at King Saud University’s Biochemistry Department in the College of Science, Riyadh, Saudi Arabia; the co- founder of MDT Canada Inc., and the founder of Child Life Development Institute, Edmonton, Canada. He has authored Biophysics and Nanotechnology of Ion Channels, Nanoscale Biophysics of the Cell, and Membrane Biophysics. He has also published about 50 peer- reviewed articles and several patents, edited two books, and has been serving on the editorial boards of Elsevier and Bentham Science journals. Dr. Ashrafuzzaman has held research and academic ranks at Bangladesh University of Engineering & Technology, University of Neuchatel (Switzerland), Helsinki University of Technology (Finland), Weill Medical College of Cornell University (USA), and University of Alberta (Canada). During 2013– 2018 he also served as a Visiting Professor at the Departments of Oncology, and Medical Microbiology and Immunology, of the University of Alberta. Dr. Ashrafuzzaman earned his highest academic degree, Doctor of Science (D.Sc.) in condensed matter physics from the University of Neuchatel, Switzerland in 2004.
Author: Mohammad Ashrafuzzaman
Publisher: Springer
ISBN: 3319774654
Category : Science
Languages : en
Pages : 396
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Book Description
Macroscopic cellular structures and functions are generally investigated using biological and biochemical approaches. But these methods are no longer adequate when one needs to penetrate deep into the small-scale structures and understand their functions. The cell is found to hold various physical structures, molecular machines, and processes that require physical and mathematical approaches to understand and indeed manipulate them. Disorders in general cellular compartments, perturbations in single molecular structures, drug distribution therein, and target specific drug-binding, etc. are mostly physical phenomena. This book will show how biophysics has revolutionized our way of addressing the science and technology of nanoscale structures of cells, and also describes the potential for manipulating the events that occur in them.
Author: Mick Wilson
Publisher: CRC Press
ISBN: 9781420035230
Category : Technology & Engineering
Languages : en
Pages : 302
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Book Description
The emergence of nanoscience portends a revolution in technology that will soon impact virtually every facet of our technological lives. Yet there is little understanding of what it is among the educated public and often among scientists and engineers in other disciplines. Furthermore, despite the emergence of undergraduate courses on the subject, no basic textbooks exist. Nanotechnology: Basic Science and Emerging Technologies bridges the gap between detailed technical publications that are beyond the grasp of nonspecialists and popular science books, which may be more science fiction than fact. It provides a fascinating, scientifically sound treatment, accessible to engineers and scientists outside the field and even to students at the undergraduate level. After a basic introduction to the field, the authors explore topics that include molecular nanotechnology, nanomaterials and nanopowders, nanoelectronics, optics and photonics, and nanobiometrics. The book concludes with a look at some cutting-edge applications and prophecies for the future. Nanoscience will bring to the world technologies that today we can only imagine and others of which we have not yet dreamt. This book lays the groundwork for that future by introducing the subject to those outside the field, sparking the imaginations of tomorrow's scientists, and challenging them all to participate in the advances that will bring nanotechnology's potential to fruition.
Author: Yuri L. Lyubchenko
Publisher: CRC Press
ISBN: 1351333127
Category : Science
Languages : en
Pages : 251
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Book Description
This book gives an accessible, detailed overview on techniques of single molecule biophysics (SMB), showing how they are applied to numerous biological problems associated with understanding the molecular mechanisms of DNA replication, transcription, and translation, as well as functioning of molecular machines. It covers major single molecule imaging and probing techniques, highlighting key strengths and limitations of each method using recent examples. The chapters begin with a discussion of single molecule fluorescence techniques followed by an overview of the atomic force microscope and its use for direct time-lapse visualization of dynamics of molecular complexes at the nanoscale, as well as applications in measurements of interactions between molecules and mechanical properties of isolated molecules and their complexes. The next chapters address magnetic tweezers and optical tweezers, including instrumentation, fundamentals of operation, and applications. A final chapter turns to nanopore transport and nanopore-based DNA sequencing technology that will play a major role in next-generation genomics and healthcare applications.
Author: Armin Kargol
Publisher:
ISBN: 9781643274126
Category :
Languages : en
Pages : 118
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Book Description
All living matter is comprised of cells; small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are a single cell and all life functions are performed by that cell. Others have groups of cells, or entire organs, specializing in one particular function. The survival of the entire organism depends on all its cells and organs fulfilling their roles. The aim of this book is to investigate the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and that, in turn, leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goal of every cell is to stay alive and to fulfil its function as a part of a larger organ or organism. This first volume is an inventory of physical transport processes occurring in cells, while the second volume will take a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.
Author: Gordon Roberts
Publisher: Springer
ISBN: 9783642167119
Category : Science
Languages : en
Pages : 0
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Book Description
The Encyclopedia of Biophysics is envisioned both as an easily accessible source of information and as an introductory guide to the scientific literature. It includes entries describing both Techniques and Systems. In the Techniques entries, each of the wide range of methods which fall under the heading of Biophysics are explained in detail, together with the value and the limitations of the information each provides. Techniques covered range from diffraction (X-ray, electron and neutron) through a wide range of spectroscopic methods (X-ray, optical, EPR, NMR) to imaging (from electron microscopy to live cell imaging and MRI), as well as computational and simulation approaches. In the Systems entries, biophysical approaches to specific biological systems or problems – from protein and nucleic acid structure to membranes, ion channels and receptors – are described. These sections, which place emphasis on the integration of the different techniques, therefore provide an inroad into Biophysics from a biological more than from a technique-oriented physical/chemical perspective. Thus the Encyclopedia is intended to provide a resource both for biophysicists interested in methods beyond those used in their immediate sub-discipline and for those readers who are approaching biophysics from either a physical or biological background.
Author: S. Pothur
Publisher: IOS Press
ISBN: 9781586032463
Category : Medical
Languages : en
Pages : 60
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Book Description
A study of how nanotechnology can be used in disease detection and treatment. It shows how nanotechnology offers sensitive tools for the early detection of cancer, discussing the use of lasers to measure optical deformability in cancer cells, and therapeutics through the use of nanomaterials.
