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Author: Werner E. G. Müller
Publisher: Springer Science & Business Media
ISBN: 3642410049
Category : Science
Languages : en
Pages : 310
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Book Description
In recent years, inorganic polymers have attracted much attention in nano-biomedicine, in particular in the area of regenerative medicine and drug delivery. This growing interest in inorganic polymers has been further accelerated by the development of new synthetic and analytical methods in the field of nanotechnology and nanochemistry. Examples for biomedical inorganic polymers that had been proven to exhibit biomedical effects and/or have been applied in preclinical or clinical trials are polysilicate / silica glass (such as naturally formed “biosilica” and synthetic “bioglass”) and inorganic polyphosphate. Some members of the mentioned biomedical inorganic polymers have already been applied e.g. as “bioglass” for bone repair and bone tissue engineering, or they are used in food processing and in dental care (inorganic polyphosphates). However, there are a number of further biological and medicinal properties of these polymers, which have been elucidated in the last few years but not yet been applied for treatment of humans. In addition to polysilicates and polyphosphate, there are a series of other inorganic polymers including polyarsenate and polyvanadate, whose biological / biomedical properties have been only marginally studied so far. Moreover, the combined application of inorganic polymers and organic polymeric molecules (formation of organic-inorganic hybrid materials) provides a variety of new materials with novel property combinations and diverse applications in nanomedicine. The planned book summarizes the present state of knowledge on a large group of inorganic polymers that had hitherto been mainly considered with regard to their chemistry but not comprehensively reviewed with respect to their potential biomedical applications.
Author: Werner E. G. Müller
Publisher: Springer Science & Business Media
ISBN: 3642410049
Category : Science
Languages : en
Pages : 310
Get Book
Book Description
In recent years, inorganic polymers have attracted much attention in nano-biomedicine, in particular in the area of regenerative medicine and drug delivery. This growing interest in inorganic polymers has been further accelerated by the development of new synthetic and analytical methods in the field of nanotechnology and nanochemistry. Examples for biomedical inorganic polymers that had been proven to exhibit biomedical effects and/or have been applied in preclinical or clinical trials are polysilicate / silica glass (such as naturally formed “biosilica” and synthetic “bioglass”) and inorganic polyphosphate. Some members of the mentioned biomedical inorganic polymers have already been applied e.g. as “bioglass” for bone repair and bone tissue engineering, or they are used in food processing and in dental care (inorganic polyphosphates). However, there are a number of further biological and medicinal properties of these polymers, which have been elucidated in the last few years but not yet been applied for treatment of humans. In addition to polysilicates and polyphosphate, there are a series of other inorganic polymers including polyarsenate and polyvanadate, whose biological / biomedical properties have been only marginally studied so far. Moreover, the combined application of inorganic polymers and organic polymeric molecules (formation of organic-inorganic hybrid materials) provides a variety of new materials with novel property combinations and diverse applications in nanomedicine. The planned book summarizes the present state of knowledge on a large group of inorganic polymers that had hitherto been mainly considered with regard to their chemistry but not comprehensively reviewed with respect to their potential biomedical applications.
Author: Dr Gareth R Williams
Publisher: Royal Society of Chemistry
ISBN: 1788016068
Category : Science
Languages : en
Pages : 392
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Book Description
This book provides a contemporary research-led overview of the applications of inorganic materials in biomedicine. It begins with a short introduction summarising key concepts in inorganic materials (layered materials, framework materials etc.), and explaining the need for new materials in medicine. It then discusses the key areas in which inorganic materials have been applied, considering: drug delivery; imaging; diagnostics and theranostics; hard matter restoration; and vaccines. Each chapter gives an overview of the major extant challenges in the research area, before presenting a systematic review of how inorganic materials have been applied to gain traction in the field. A clear focus is maintained on the fate of the applied materials in vivo, clinical considerations, and the path to translation from lab to clinic. With contributions from leading researchers, Biomedical Applications of Inorganic Materials will provide a comprehensive introduction for advanced undergraduates, postgraduates and researchers wishing to learn about the topic.
Author: Karsten König
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3110383500
Category : Science
Languages : en
Pages : 369
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Book Description
Nanostructuring of materials is a task at the heart of many modern disciplines in mechanical engineering, as well as optics, electronics, and the life sciences. This book includes an introduction to the relevant nonlinear optical processes associated with very short laser pulses for the generation of structures far below the classical optical diffraction limit of about 200 nanometers as well as coverage of state-of-the-art technical and biomedical applications. These applications include silicon and glass wafer processing, production of nanowires, laser transfection and cell reprogramming, optical cleaning, surface treatments of implants, nanowires, 3D nanoprinting, STED lithography, friction modification, and integrated optics. The book highlights also the use of modern femtosecond laser microscopes and nanoscopes as novel nanoprocessing tools.
Author: Xiang C Zhang
Publisher: Smithers Rapra
ISBN: 1909030414
Category : Medical
Languages : en
Pages : 256
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Book Description
This book provides a practical guide to the use and applications of inorganic biomaterials. It begins by introducing the concept of inorganic biomaterials, which includes bioceramics and bioglass. This concept is further extended to hybrid biomaterials consisting of inorganic and organic materials to mimic natural biomaterials. The book goes on to provide the reader with information on biocompatibility, bioactivity and bioresorbability. The concept of the latter is important because of the increasing role resorbable biomaterials are playing in implant applications. The book also introduces a new concept on mechanical compatibility - 'mechacompatibility'. Almost all implant biomaterials employed to date, such as metal and ceramic implants, do not meet this biological requirement as they have far higher modulus than any biomaterials in the body. The practical techniques that are used in the characterization of biomaterials, including chemical, physical, biological, microscopy and mechanical characterization are described. Some specialised techniques are also introduced such as Synchrotron Micro-Computed Tomography (u-CT) and Magnetic Resonance Imaging (MRI). The reader is given important information on new biomaterials development for orthopaedic and other areas, including controlled release technology, hydroxyapatite and hybrid bioresorbable materials. Finally the book provides a guide to regulatory considerations, an area which is often overlooked, but is an important part of R&D and manufacturing of medical materials and devices.
Author: Sangamesh G. Kum bar
Publisher: Newnes
ISBN: 0123972906
Category : Technology & Engineering
Languages : en
Pages : 421
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Book Description
Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future
Author: Abraham J. Domb
Publisher: John Wiley & Sons
ISBN: 1118015800
Category : Technology & Engineering
Languages : en
Pages : 594
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Book Description
This book focuses on biodegradable polymers that are already in clinical use or under clinical development. Synthetic and natural polymers will be included. This excludes polymers that have been investigated and did not reach clinical development. The purpose of this book is to provide updated status of the polymers that are clinical use and those that are now being developed for clinical use and hopefully will reach the clinic during the next 5 years. The book provides information that of interest to academics and practicing researchers including chemists, biologists and bioengineers and users: physicians, pharmacists.
Author: Masoud Mozafari
Publisher: Elsevier
ISBN: 0128166045
Category : Technology & Engineering
Languages : en
Pages : 430
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Book Description
Advanced Functional Polymers for Biomedical Applications presents novel techniques for the preparation and characterization of functionalized polymers, enabling researchers, scientists and engineers to understand and utilize their enhanced functionality in a range of cutting-edge biomedical applications. Provides systematic coverage of the major types of functional polymers, discussing their properties, preparation techniques and potential applications Presents new synthetic approaches alongside the very latest polymer processing and characterization methods Unlocks the potential of functional polymers to support ground-breaking techniques for drug and gene delivery, diagnostics, tissue engineering and regenerative medicine
Author: Deepak Pathania
Publisher: Nova Science Publishers
ISBN: 9781536136135
Category : Technology & Engineering
Languages : en
Pages : 435
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Book Description
Polymers have generated considerable interest in a large number of technologically important fields such as human healthcare systems. Polymers represent a very important domain of materials and have become an integral part of day to day human life. Polymers exist in nature; they have been and continue to be an integral part of the universe. This book is intended for scientists and researchers to use in their research or in their professional practice in polymer chemistry and its biomedical applications. Multiple biological, synthetic and hybrid polymers are used for multiple medical applications. A wide range of different polymers are available, and they have the advantage to be tunable in physical, chemical and biological properties and in a wide range to match the requirements of specific applications. This book gives a brief overview about the introduction and developments of polymers for different applications. The biomedical polymers comprise not only bulk materials, but also coatings and pharmaceutical nano-carriers for drugs. The surface modification of the inorganic nanoparticles with a physically or chemically end-tethered polymer chain has been employed to overcome the problems associated with the polymers. Chemically attached polymer chains not only stabilize the inorganic nanoparticles, but also lead to photosensitivity, bioactivity, biocompatibility and pharmacological properties in the composites. Polymer encapsulated silica nanocomposites (mesoporous) have potential applications in different fields, such as optics, bio-catalysis, microelectronics bone tissue engineering, coatings cosmetics, inks, agriculture, drug release systems, diagnoses, enzyme imaging, temperature-responsive materials, and thermosensitive vehicles for cellular imaging. Polymer grafted nanosized particles are known to have excellent properties such as good dispersion ability in solvents and polymer matrices. Polymer-based controlled drug delivery systems have some specific advantages, such as improved efficiency and reduced toxicity. The incorporation of a thermoresponsive polymer layer often enhances protein absorption and specific biomolecular tagging through hydrogen bonding. As a result, the nanocomposite gets cleared from the body at a faster rate (blood residence becomes low). This book is composed of fourteen edited chapters; it is intended for scientists and researchers to use in their research or in their professional practice in polymer chemistry and its biomedical applications.
Author: Kishor Kumar Sadasivuni
Publisher: Springer
ISBN: 3030047415
Category : Technology & Engineering
Languages : en
Pages : 409
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Book Description
This book presents a thorough discussion of the physics, biology, chemistry and medicinal science behind a new and important area of materials science and engineering: polymer nanocomposites. The tremendous opportunities of polymer nanocomposites in the biomedical field arise from their multitude of applications and their ability to satisfy the vastly different functional requirements for each of these applications. In the biomedical field, a polymer nanocomposite system must meet certain design and functional criteria, including biocompatibility, biodegradability, mechanical properties, and, in some cases, aesthetic demands. The content of this book builds on what has been learnt in elementary courses about synthesising polymers, different nanoparticles, polymer composites, biomedical requirements, uses of polymer nanocomposites in medicine as well as medical devices and the major mechanisms involved during each application. The impact of hybrid nanofillers and synergistic composite mixtures which are used extensively or show promising outcomes in the biomedical field are also discussed. These novel materials vary from inorganic/ceramic-reinforced nanocomposites for mechanical property improvement to peptide-based nanomaterials, with the chemistry designed to render the entire material biocompatible.
Author: Stanislav Rangelov
Publisher: CRC Press
ISBN: 1439869073
Category : Science
Languages : en
Pages : 504
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Book Description
Polymeric and hybrid nanoparticles have received increased scientific interest in terms of basic research as well as commercial applications, promising a variety of uses for nanostructures in fields including bionanotechnology and medicine. Condensing the relevant research into a comprehensive reference, Polymer and Polymer-Hybrid Nanoparticles: From Synthesis to Biomedical Applications covers an array of topics from synthetic procedures and macromolecular design to possible biomedical applications of nanoparticles and materials based on original and unique polymers. The book presents a well-rounded picture of objects ranging from simple polymeric micelles to complex hybrid polymer-based nanostructures, detailing synthetic procedures, techniques for characterization and analysis, properties, and behavior in selective solvents and dispersions. Each chapter contains background and introductory information, summarizing generalities on the nanosystems being discussed. The chapters also describe representative works of experts and provide in-depth, focused discussions. The authors present current knowledge on the following topics: Designed synthesis of functional polymers Construction of block copolymer micellar and nonmicellar self-assembled structures Construction of organic–organic hybrid nanosized particles Construction of organic–inorganic hybrid nanoparticles and nanoassemblies The final chapter addresses biological applications of polymeric nanoparticles, including delivery of low-molecular-weight drugs, macromolecular drugs, imaging and diagnostics, and photodynamic therapy. Summarizing important developments in the field, the authors condense relevant research into a comprehensive resource.
