Author: Roustem N. Miftahof
Publisher: Springer
ISBN: 3319596772
Category : Medical
Languages : en
Pages : 290
Book Description
This book concerns the mathematical modeling and computer simulation of the human stomach. It follows the four modern P’s (prevention, prediction, personalization, and precision in medicine) approach in addressing the highly heterogeneous nature of processes underlying gastric motility disorders manifested as gastroparesis, functional dyspepsia, myenteric enteropathy etc. The book comprehensively guides readers through the fundamental theoretical concepts to complex physiological models of the organ. This requires a deep and thorough understanding of driving pathophysiological mechanisms as well as the collaborative effort of specialists working in fundamental and biological science. Such a multidisciplinary partnership is vital because it upholds gnostic capabilities and provides the exchange of thoughts and ideas thus offering broad perspectives into the evolution and management of diseases. The book is a valuable resource for applied mathematicians, computational biologists, bioengineers, physicians, physiologists and researchers working in various fields of biomedicine.
Biomechanics of the Human Stomach
Mathematical Foundations and Biomechanics of the Digestive System
Author: Roustem N. Miftahof
Publisher: Cambridge University Press
ISBN: 1139485776
Category : Technology & Engineering
Languages : en
Pages : 241
Book Description
Mathematical modelling of physiological systems promises to advance our understanding of complex biological phenomena and pathophysiology of diseases. In this book, the authors adopt a mathematical approach to characterize and explain the functioning of the gastrointestinal system. Using the mathematical foundations of thin shell theory, the authors patiently and comprehensively guide the reader through the fundamental theoretical concepts, via step-by-step derivations and mathematical exercises, from basic theory to complex physiological models. Applications to nonlinear problems related to the biomechanics of abdominal viscera and the theoretical limitations are discussed. Special attention is given to questions of complex geometry of organs, effects of boundary conditions on pellet propulsion, as well as to clinical conditions, e.g. functional dyspepsia, intestinal dysrhythmias and the effect of drugs to treat motility disorders. With end of chapter problems, this book is ideal for bioengineers and applied mathematicians.
Publisher: Cambridge University Press
ISBN: 1139485776
Category : Technology & Engineering
Languages : en
Pages : 241
Book Description
Mathematical modelling of physiological systems promises to advance our understanding of complex biological phenomena and pathophysiology of diseases. In this book, the authors adopt a mathematical approach to characterize and explain the functioning of the gastrointestinal system. Using the mathematical foundations of thin shell theory, the authors patiently and comprehensively guide the reader through the fundamental theoretical concepts, via step-by-step derivations and mathematical exercises, from basic theory to complex physiological models. Applications to nonlinear problems related to the biomechanics of abdominal viscera and the theoretical limitations are discussed. Special attention is given to questions of complex geometry of organs, effects of boundary conditions on pellet propulsion, as well as to clinical conditions, e.g. functional dyspepsia, intestinal dysrhythmias and the effect of drugs to treat motility disorders. With end of chapter problems, this book is ideal for bioengineers and applied mathematicians.
Integrated Nano-Biomechanics
Author: Takami Yamaguchi
Publisher: William Andrew
ISBN: 0323389597
Category : Medical
Languages : en
Pages : 316
Book Description
Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production. This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases. - Provides knowledge of integrated biomechanics, focusing on nano-scale, in this rapidly growing research field - Explains how the different technologies can be integrated and applied in a variety of biomedical application fields, as well as for alternative energy sources - Uses a collaborative, multidisciplinary approach to provide a comprehensive coverage of nano-biomechanics
Publisher: William Andrew
ISBN: 0323389597
Category : Medical
Languages : en
Pages : 316
Book Description
Integrated Nano-Biomechanics provides an integrated look into the rapidly evolving field of nanobiomechanics. The book demystifies the processes in living organisms at the micro- and nano-scale through mechanics, using theoretical, computational and experimental means. The book develops the concept of integrating different technologies along the hierarchical structure of biological systems and clarifies biomechanical interactions among different levels for the analysis of multi-scale pathophysiological phenomena. With a focus on nano-scale processes and biomedical applications, it is shown how knowledge obtained can be utilized in a range of areas, including diagnosis and treatment of various human diseases and alternative energy production. This book is based on collaboration of researchers from a unique combination of fields, including biomechanics, computational mechanics, GPU application, electron microscopy, biology of motile micro-organisms, entomological mechanics and clinical medicine. The book will be of great interest to scientists and researchers involved in disciplines, such as micro- and nano-engineering, bionanotechnology, biomedical engineering, micro- and nano-scale fluid-mechanics (such as in MEMS devices), nanomedicine and microbiology, as well as industries such as optical devices, computer simulation, plant based energy sources and clinical diagnosis of the gastric diseases. - Provides knowledge of integrated biomechanics, focusing on nano-scale, in this rapidly growing research field - Explains how the different technologies can be integrated and applied in a variety of biomedical application fields, as well as for alternative energy sources - Uses a collaborative, multidisciplinary approach to provide a comprehensive coverage of nano-biomechanics
Clinical Mechanics in the Gut: An Introduction
Author: Hans Gregersen
Publisher: Bentham Science Publishers
ISBN: 1681081180
Category : Medical
Languages : en
Pages : 252
Book Description
The gastrointestinal tract is a series of organs each with distinct mechanical functions. Each organ within the system brings food contents in the gut lumen to the site of absorption through separate mechanical functions. These mechanical functions are generated by a fine-tuned interaction between neuronal networks and active muscle layers. The passive components of the gastrointestinal wall such as the collagen-rich submucosa also play an important role in these mechanical actions. Clinical Mechanics in The Gut provides a thorough understanding of the anatomy and biomechanics of the physiological function and pathophysiology of the gastrointestinal tract. The book first gives an introduction to readers about the physical geometry of the gastrointestinal tract followed by a detailed explanation of biomechanical theory and its application to approximating and modeling gut mechanics. This is expanded further by detailed explanations of gut muscle and motor nerve functions in proceeding chapters. A biomechanical evaluation of disorders of regulatory mechanisms such as achalasia and Hirschsprung disease and disorders of effector mechanisms such as reflux disease, systemic sclerosis of the gastrointestinal tract and colonic diverticular disease are also included. Readers will, therefore, gain an understanding about clinical problems in gastroenterology from a bioengineering and modeling perspective. Clinical Mechanics in The Gut is a useful reference for gastroenterology researchers, biomedical engineers and systems biologists seeking to understand the physiology of the gut and applying this knowledge to surgical procedures, computer-based modeling systems and robotics.
Publisher: Bentham Science Publishers
ISBN: 1681081180
Category : Medical
Languages : en
Pages : 252
Book Description
The gastrointestinal tract is a series of organs each with distinct mechanical functions. Each organ within the system brings food contents in the gut lumen to the site of absorption through separate mechanical functions. These mechanical functions are generated by a fine-tuned interaction between neuronal networks and active muscle layers. The passive components of the gastrointestinal wall such as the collagen-rich submucosa also play an important role in these mechanical actions. Clinical Mechanics in The Gut provides a thorough understanding of the anatomy and biomechanics of the physiological function and pathophysiology of the gastrointestinal tract. The book first gives an introduction to readers about the physical geometry of the gastrointestinal tract followed by a detailed explanation of biomechanical theory and its application to approximating and modeling gut mechanics. This is expanded further by detailed explanations of gut muscle and motor nerve functions in proceeding chapters. A biomechanical evaluation of disorders of regulatory mechanisms such as achalasia and Hirschsprung disease and disorders of effector mechanisms such as reflux disease, systemic sclerosis of the gastrointestinal tract and colonic diverticular disease are also included. Readers will, therefore, gain an understanding about clinical problems in gastroenterology from a bioengineering and modeling perspective. Clinical Mechanics in The Gut is a useful reference for gastroenterology researchers, biomedical engineers and systems biologists seeking to understand the physiology of the gut and applying this knowledge to surgical procedures, computer-based modeling systems and robotics.
The Impact of Food Bioactives on Health
Author: Kitty Verhoeckx
Publisher: Springer
ISBN: 3319161040
Category : Technology & Engineering
Languages : en
Pages : 341
Book Description
“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.
Publisher: Springer
ISBN: 3319161040
Category : Technology & Engineering
Languages : en
Pages : 341
Book Description
“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.
Materials for Biomedical Simulation
Author: Arnab Chanda
Publisher: Springer Nature
ISBN: 9819950643
Category : Technology & Engineering
Languages : en
Pages : 199
Book Description
The book provides an overview of prospective material simulants for hard tissues, such as knee joints, hip joint, and bones, and soft tissues, such as skin, muscles, and functional organs. These materials can repair, replace the functionality, or mimic the mechanical, structural, and biological properties of the parent tissue. This book discusses hard and soft human tissue simulating biomaterials under a single umbrella, covering a broad area of design and development of biomaterials, implants, and multi-functional materials along with their characterization. The progress in emerging biomaterials has increased manifold in the recent decades with the unprecedented focus on healthcare technologies. This book is dedicated to ground-breaking research in biomaterials and highlights the current trends and future roadmap of different materials for simulation of hard and soft tissues. Authored by prominent researchers around the globe, the chapters of this book emphasize recent advances in biomedical material simulation. This book brings together novel contributions to different aspects of hard and soft human tissue-based biomaterials, including recent advances and emerging developments in designing and developing simulants for tissue replacement alternatives. This book is anticipated to serve as a key reference textbook for research in tissue engineering & biomedical engineering, biomaterials, biomechanics, and implant & medical device development with contributed chapters solicited in the areas of soft materials, such as elastomers, hydrogels, etc., for various applications; auxetic metamaterials; additive manufacturing of bio-implants; artificial tissues and organs; development of biomimetic materials; medical implants and biomedical device design; bioinspired and bio-tribological materials; advances in materials science for biomaterial applications; biomechanical characterization of hard and soft human tissues; bioprinting and nano-biomaterials.
Publisher: Springer Nature
ISBN: 9819950643
Category : Technology & Engineering
Languages : en
Pages : 199
Book Description
The book provides an overview of prospective material simulants for hard tissues, such as knee joints, hip joint, and bones, and soft tissues, such as skin, muscles, and functional organs. These materials can repair, replace the functionality, or mimic the mechanical, structural, and biological properties of the parent tissue. This book discusses hard and soft human tissue simulating biomaterials under a single umbrella, covering a broad area of design and development of biomaterials, implants, and multi-functional materials along with their characterization. The progress in emerging biomaterials has increased manifold in the recent decades with the unprecedented focus on healthcare technologies. This book is dedicated to ground-breaking research in biomaterials and highlights the current trends and future roadmap of different materials for simulation of hard and soft tissues. Authored by prominent researchers around the globe, the chapters of this book emphasize recent advances in biomedical material simulation. This book brings together novel contributions to different aspects of hard and soft human tissue-based biomaterials, including recent advances and emerging developments in designing and developing simulants for tissue replacement alternatives. This book is anticipated to serve as a key reference textbook for research in tissue engineering & biomedical engineering, biomaterials, biomechanics, and implant & medical device development with contributed chapters solicited in the areas of soft materials, such as elastomers, hydrogels, etc., for various applications; auxetic metamaterials; additive manufacturing of bio-implants; artificial tissues and organs; development of biomimetic materials; medical implants and biomedical device design; bioinspired and bio-tribological materials; advances in materials science for biomaterial applications; biomechanical characterization of hard and soft human tissues; bioprinting and nano-biomaterials.
The Biomechanics of Impact Injury
Author: Albert I. King
Publisher: Springer
ISBN: 3319497928
Category : Technology & Engineering
Languages : en
Pages : 706
Book Description
This text acquaints the reader on the biomechanics of injury to the human body caused by impact and the use of computer models to simulate impact events. It provides a basic understanding of the biomechanics of the injuries resulting from the impact to the head, neck, chest, abdomen, spine, pelvis and the lower extremities, including the foot and ankle. Other topics include side impact, car-pedestrian impact, effectiveness of automotive restraint systems and sports-related injuries. Featuring problems and PowerPoint slides for lectures, the volume is ideal for students in graduate programs in biomechanics, as well as practicing engineers, and researchers in the life sciences concerned with orthopedics.
Publisher: Springer
ISBN: 3319497928
Category : Technology & Engineering
Languages : en
Pages : 706
Book Description
This text acquaints the reader on the biomechanics of injury to the human body caused by impact and the use of computer models to simulate impact events. It provides a basic understanding of the biomechanics of the injuries resulting from the impact to the head, neck, chest, abdomen, spine, pelvis and the lower extremities, including the foot and ankle. Other topics include side impact, car-pedestrian impact, effectiveness of automotive restraint systems and sports-related injuries. Featuring problems and PowerPoint slides for lectures, the volume is ideal for students in graduate programs in biomechanics, as well as practicing engineers, and researchers in the life sciences concerned with orthopedics.
Biomechanics of the Gastrointestinal Tract
Author: Hans Gregersen
Publisher: Springer Science & Business Media
ISBN: 1447137426
Category : Medical
Languages : en
Pages : 294
Book Description
Biomechanics of the Gastrointestinal Tract is an up-to-date book for researchers on the study of the mechanical properties and the motor system of the gastrointestinal tract. A well-illustrated book, it provides a comprehensive overview to relevant tissue geometry, morphology and biomechanical theory. Separate chapters cover smooth muscle and nerve function including the application to animal and human studies of motility, symptoms and pain, determination of the true resting state, history-dependent properties, and tissue remodelling in disease. Several methods and diagnostic applications such as determination of in vivo length-tension diagrams and multimodal pain testing are completely new but will undoubtedly be used by many in the future. New non-invasive imaging techniques based on ultrasound, MR- and CT-scanning in combination with balloon distension are emerging as the techniques for future in vivo studies.
Publisher: Springer Science & Business Media
ISBN: 1447137426
Category : Medical
Languages : en
Pages : 294
Book Description
Biomechanics of the Gastrointestinal Tract is an up-to-date book for researchers on the study of the mechanical properties and the motor system of the gastrointestinal tract. A well-illustrated book, it provides a comprehensive overview to relevant tissue geometry, morphology and biomechanical theory. Separate chapters cover smooth muscle and nerve function including the application to animal and human studies of motility, symptoms and pain, determination of the true resting state, history-dependent properties, and tissue remodelling in disease. Several methods and diagnostic applications such as determination of in vivo length-tension diagrams and multimodal pain testing are completely new but will undoubtedly be used by many in the future. New non-invasive imaging techniques based on ultrasound, MR- and CT-scanning in combination with balloon distension are emerging as the techniques for future in vivo studies.
Anthropometry and Biomechanics
Author: Ronald Easterby
Publisher: Springer Science & Business Media
ISBN: 1468410989
Category : Technology & Engineering
Languages : en
Pages : 310
Book Description
Assessment of the physical dimensions of the human body and application of this knowledge to the design of tools, equip ment, and work are certainly among the oldest arts and sciences. It would be an easy task if all anthropometric dimensions, of all people, would follow a general rule. Thus, philosophers and artists embedded their ideas about the most aesthetic proportions into ideal schemes of perfect proportions. "Golden sections" were developed in ancient India, China, Egypt, and Greece, and more recently by Leonardo DaVinci, or Albrecht Durer. However, such canons are fictive since actual human dimensions and proportions vary greatly among individuals. The different physical appearances often have been associated with mental, physiological and behavioral characteristics of the individuals. Hypocrates (about 460-377 BC) taught that there are four temperaments (actually, body fluids) represented by four body types. The psychiatrist Ernst Kretchmer (1888-1964) proposed that three typical somatotypes (pyknic, athletic, aesthenic) could reflect human character traits. Since the 1940's, W. H. Sheldon and his coworkers devised a system of three body physiques (endo-, meso-, ectomorphic). The classification was originally qualitative, and only recently has been developed to include actual measurements.
Publisher: Springer Science & Business Media
ISBN: 1468410989
Category : Technology & Engineering
Languages : en
Pages : 310
Book Description
Assessment of the physical dimensions of the human body and application of this knowledge to the design of tools, equip ment, and work are certainly among the oldest arts and sciences. It would be an easy task if all anthropometric dimensions, of all people, would follow a general rule. Thus, philosophers and artists embedded their ideas about the most aesthetic proportions into ideal schemes of perfect proportions. "Golden sections" were developed in ancient India, China, Egypt, and Greece, and more recently by Leonardo DaVinci, or Albrecht Durer. However, such canons are fictive since actual human dimensions and proportions vary greatly among individuals. The different physical appearances often have been associated with mental, physiological and behavioral characteristics of the individuals. Hypocrates (about 460-377 BC) taught that there are four temperaments (actually, body fluids) represented by four body types. The psychiatrist Ernst Kretchmer (1888-1964) proposed that three typical somatotypes (pyknic, athletic, aesthenic) could reflect human character traits. Since the 1940's, W. H. Sheldon and his coworkers devised a system of three body physiques (endo-, meso-, ectomorphic). The classification was originally qualitative, and only recently has been developed to include actual measurements.
Modelling in Medicine and Biology
Author: C. A. Brebbia
Publisher: WIT Press
ISBN: 1845645723
Category : Science
Languages : en
Pages : 221
Book Description
The idea of preparing this volume originated from the ever increasing importance of computational modelling of complex problems in medicine. Considerable advances have been made in this area as demonstrated by the continued success of the International Conference on Modelling in Medicine and Biology organised by the Wessex Institute of Technology.The work reported at those meetings and the research carried out at the Wessex Institute of Technology indicated the increasing interaction and collaboration between medical and engineering scientists. Advances presented at these conferences are now being used in practice for a wide range of medical and surgical applications.The considerable improvements and evolution of the field has led to some of the best scientists, who have participated in our conferences, to write an article on their most recent research. This has led to thirteen outstanding articles published in this volume which encompass important areas of biomedical modelling.
Publisher: WIT Press
ISBN: 1845645723
Category : Science
Languages : en
Pages : 221
Book Description
The idea of preparing this volume originated from the ever increasing importance of computational modelling of complex problems in medicine. Considerable advances have been made in this area as demonstrated by the continued success of the International Conference on Modelling in Medicine and Biology organised by the Wessex Institute of Technology.The work reported at those meetings and the research carried out at the Wessex Institute of Technology indicated the increasing interaction and collaboration between medical and engineering scientists. Advances presented at these conferences are now being used in practice for a wide range of medical and surgical applications.The considerable improvements and evolution of the field has led to some of the best scientists, who have participated in our conferences, to write an article on their most recent research. This has led to thirteen outstanding articles published in this volume which encompass important areas of biomedical modelling.