Biomechanics of Soft Tissue in Cardiovascular Systems PDF Download
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Author: Gerhard A. Holzapfel
Publisher: Springer
ISBN: 370912736X
Category : Technology & Engineering
Languages : en
Pages : 348
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Book Description
The book is written by leading experts in the field presenting an up-to-date view of the subject matter in a didactically sound manner. It presents a review of the current knowledge of the behaviour of soft tissues in the cardiovascular system under mechanical loads, and the importance of constitutive laws in understanding the underlying mechanics is highlighted. Cells are also described together with arteries, tendons and ligaments, heart, and other biological tissues of current research interest in biomechanics. This includes experimental, continuum mechanical and computational perspectives, with the emphasis on nonlinear behaviour, and the simulation of mechanical procedures such as balloon angioplasty.
Author: Gerhard A. Holzapfel
Publisher: Springer
ISBN: 370912736X
Category : Technology & Engineering
Languages : en
Pages : 348
Get Book Here
Book Description
The book is written by leading experts in the field presenting an up-to-date view of the subject matter in a didactically sound manner. It presents a review of the current knowledge of the behaviour of soft tissues in the cardiovascular system under mechanical loads, and the importance of constitutive laws in understanding the underlying mechanics is highlighted. Cells are also described together with arteries, tendons and ligaments, heart, and other biological tissues of current research interest in biomechanics. This includes experimental, continuum mechanical and computational perspectives, with the emphasis on nonlinear behaviour, and the simulation of mechanical procedures such as balloon angioplasty.
Author: Ricardo Armentano
Publisher:
ISBN: 9780750312813
Category : TECHNOLOGY & ENGINEERING
Languages : en
Pages : 0
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Book Description
"Modeling has provided not only answers to questions related to normal or pathological function but also predicted multiple adaptations of the total and individual dynamic structures that are included in cardiovascular research. The original idea of this book was to produce a textbook to be used for the course 'Modeling in Biomechanics and Mechanobiology', which is oriented to Artificial Organs and Tissue Engineering at Buenos Aires University, Argentina. This book brings together the challenges and experiences of academic scientists, leading engineers, industry researchers and students to enable them to analyse results of all aspects of biomechanics and biomedical engineering. It also provides a springboard to discuss the practical challenges and to propose solutions on this complex subject." -- Prové de l'editor.
Author: Peter R. Hoskins
Publisher: Springer
ISBN: 3319464078
Category : Medical
Languages : en
Pages : 462
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Book Description
This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.
Author: Michael S. Sacks
Publisher: Springer
ISBN: 3030019934
Category : Science
Languages : en
Pages : 500
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Book Description
This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.
Author: Gerhard A. Holzapfel
Publisher: Springer
ISBN: 3319414755
Category : Technology & Engineering
Languages : en
Pages : 319
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Book Description
The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues. The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.
Author: Ugo Andreaus
Publisher: Springer Science & Business Media
ISBN: 940074269X
Category : Technology & Engineering
Languages : en
Pages : 208
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Book Description
This book collects the state-of-art and new trends in image analysis and biomechanics. It covers a wide field of scientific and cultural topics, ranging from remodeling of bone tissue under the mechanical stimulus up to optimizing the performance of sports equipment, through the patient-specific modeling in orthopedics, microtomography and its application in oral and implant research, computational modeling in the field of hip prostheses, image based model development and analysis of the human knee joint, kinematics of the hip joint, micro-scale analysis of compositional and mechanical properties of dentin, automated techniques for cervical cell image analysis, and biomedical imaging and computational modeling in cardiovascular disease. The book will be of interest to researchers, Ph.D students, and graduate students with multidisciplinary interests related to image analysis and understanding, medical imaging, biomechanics, simulation and modeling, experimental analysis
Author: Michel Labrosse
Publisher: CRC Press
ISBN: 1315280280
Category : Medical
Languages : en
Pages : 401
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Book Description
The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.
Author: Elena Aikawa
Publisher: BoD – Books on Demand
ISBN: 9535111507
Category : Medical
Languages : en
Pages : 544
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Book Description
Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.
Author: Ming Zhang
Publisher: CRC Press
ISBN: 1466588039
Category : Medical
Languages : en
Pages : 372
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Book Description
Computational biomechanics is an emerging research field that seeks to understand the complex biomechanical behaviors of normal and pathological human joints to come up with new methods of orthopedic treatment and rehabilitation. Computational Biomechanics of the Musculoskeletal System collects the latest research and cutting-edge techniques used in computational biomechanics, focusing on orthopedic and rehabilitation engineering applications. The book covers state-of-the-art techniques and the latest research related to computational biomechanics, in particular finite element analysis and its potential applications in orthopedics and rehabilitation engineering. It offers a glimpse into the exciting potentials for computational modeling in medical research and biomechanical simulation. The book is organized according to anatomical location—foot and ankle, knee, hip, spine, and head and teeth. Each chapter details the scientific questions/medical problems addressed by modeling, basic anatomy of the body part, computational model development and techniques used, related experimental studies for model setup and validation, and clinical applications. Plenty of useful biomechanical information is provided for a variety of applications, especially for the optimal design of body support devices and prosthetic implants. This book is an excellent resource for engineering students and young researchers in bioengineering. Clinicians involved in orthopedics and rehabilitation engineering may find this work to be both informative and highly relevant to their clinical practice.
Author: Jay D. Humphrey
Publisher: Springer Science & Business Media
ISBN: 038721576X
Category : Science
Languages : en
Pages : 766
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Book Description
This text presents a general introduction to soft tissue biomechanics. One of its primary goals is to introduce basic analytical, experimental and computational methods. In doing so, it enables readers to gain a relatively complete understanding of the biomechanics of the heart and vasculature.
