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Author: John A. Mol
Publisher: Springer
ISBN: 9781475786422
Category : Science
Languages : en
Pages : 314
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Book Description
Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.
Author: John A. Mol
Publisher: Springer Science & Business Media
ISBN: 0306468328
Category : Science
Languages : en
Pages : 309
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Book Description
Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.
Author: Margot M. Ip
Publisher: Springer Science & Business Media
ISBN: 9780306463976
Category : Medical
Languages : en
Pages : 366
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Book Description
This book is a bench manual that provides in one volume all theimportant and unique technologies necessary to studies of mammarygland biology and breast cancer. The chapters are written by expertsin each area with an emphasis on nitty-gritty details that are keypoints for the successful use of a method. Sections include "in""vivo" model systems, special techniques for "in vivo"studies, "in vitro" model systems, and molecular analysis and genetransfer techniques.
Author: Mina Bissell
Publisher:
ISBN: 9780879699062
Category : Medical
Languages : en
Pages : 0
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Book Description
Studies of mammary gland biology are critically important given the prevalence of breast cancer in the population. There are many other reasons to study this organ, however. It represents an excellent model system for research into developmental mechanisms, gene regulation, tissue organization, hormonal action, secretion, and stem cell biology, revealing general principles that can be extended to other organs and tissues. This book provides valuable lessons for all cell, developmental, and cancer biologists.
Author: R. Michael Akers
Publisher: John Wiley & Sons
ISBN: 1119279674
Category : Technology & Engineering
Languages : en
Pages : 291
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Book Description
Michael Akers provides the basics for understanding mammary development and lactation and conveys the critical regulatory events in lactation. This text willl prove to be an invaluable overview of mamorary development and lactation for undergraduates and graduates studying lactation, new researchers, and as a review for established scientists. Additionally, the book will be an important resource for professionals in the animal and dairy industry and for those in other scientific disciplines such as food chemistry, cell biology, and endocrinology whose work is closely tied to mammary gland development and function. Lactation and the Mammary Gland covers growth and development of the mammary gland including comparisons between species. It imparts and emphasizes the critical nature of mammary growth and the onset of lactation at the time of parturition. Special emphasis is given to the endocrine and growth factor regulation of both mammogenesis and lactogenesis. A thorough discussion of the role of growth hormone in development and maintenance of lactation or galactopoiesis adds to this book's value as a text and reference. The author reviews the presence of hormones, growth factors, and other bioactive compounds in milk and mammary secretions as well as the potential for use of the mammary gland as a bioreactor in the pharmaceutical industry. A description of the nutritional and management factors in milk production round out the book's comprehensive coverage.
Author: Michael L. Power
Publisher: JHU Press
ISBN: 1421420430
Category : Science
Languages : en
Pages : 297
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Book Description
Everything you ever wanted to know about the substance that binds all mammals together. After drawing its first breath, every newborn mammal turns his or her complete attention to obtaining milk. This primal act was once thought to stem from a basic fact: milk provides the initial source of calories and nutrients for all mammalian young. But it turns out that milk is a much more complicated biochemical cocktail and provides benefits beyond nutrition. In this fascinating book, biologists Michael L. Power and Jay Schulkin reveal this liquid’s evolutionary history and show how its ingredients have changed over many millions of years to become a potent elixir. Power and Schulkin walk readers through the early origins of the mammary gland and describe the incredible diversification of milk among the various mammalian lineages. After revealing the roots of lactation, the authors describe the substances that naturally occur in milk and discuss their biological functions. They reveal that mothers pass along numerous biochemical signals to their babies through milk. The authors explain how milk boosts an infant’s immune system, affects an infant’s metabolism and physiology, and helps inoculate and feed the baby’s gut microbiome. Throughout the book, the authors weave in stories from studies of other species, explaining how comparative research sheds light on human lactation. The authors then turn their attention to the fascinating topic of cross-species milk consumption—something only practiced by certain humans who evolved an ability to retain lactase synthesis into adulthood. The first book to discuss milk from a comparative and evolutionary perspective, Power and Schulkin’s masterpiece reveals the rich biological story of the common thread that connects all mammals.
Author: Marc E. Lippman
Publisher: Springer Science & Business Media
ISBN: 9780898383683
Category : Medical
Languages : en
Pages : 424
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Book Description
Where do you begin to look for a recent, authoritative article on the diagnosis or management of particular malignancy? The few general oncology text books are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre quently publish good in-depth reviews of cancer topics, and published sym posium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by divid ing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Author: Larry K. Pickering
Publisher: Springer Science & Business Media
ISBN: 1475742428
Category : Medical
Languages : en
Pages : 506
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Book Description
Protecting Infants through Human Milk: Advancing the Scientific Evidence provides a forum in which basic scientists, clinicians, epidemiologists, and policy makers exchange the latest findings regarding the effects of human milk and breastfeeding on infant and maternal health, thereby fostering new and promising collaborations. This volume also integrates data from animal and in vitro laboratory studies with clinical and population studies to examine human milk production and composition, the mechanisms of infant protection and/or risk from human milk feeding, and proposed interventions related to infant feeding practices. Additionally, it stimulates critical evaluation of, and advances in, the scientific evidence base and research methods, and identifies the research priorities in various areas.
Author: Jeffrey J. Zimmerman
Publisher: John Wiley & Sons
ISBN: 1119350859
Category : Medical
Languages : en
Pages : 1136
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Book Description
Provides a fully revised Eleventh Edition of the definitive reference to swine health and disease Diseases of Swine has been the definitive reference on swine health and disease for over 60 years. This new edition has been completely revised to include the latest information, developments, and research in the field. Now with full color images throughout, this comprehensive and authoritative resource has been redesigned for improved consistency and readability, with a reorganized format for more intuitive access to information. Diseases of Swine covers a wide range of essential topics on swine production, health, and management, with contributions from more than 100 of the foremost international experts in the field. This revised edition makes the information easy to find and includes expanded information on welfare and behavior. A key reference for anyone involved in the swine industry, Diseases of Swine, Eleventh Edition: Presents a thorough revision to the gold-standard reference on pig health and disease Features full color images throughout the book Includes information on the most current advances in the field Provides comprehensive information on swine welfare and behavior Offers a reorganized format to make the information more accessible Written for veterinarians, academicians, students, and individuals and agencies responsible for swine health and public health, Diseases of Swine, Eleventh Edition is an essential guide to swine health. "The 11th edition of Diseases of Swine continues to serve as the gold-standard resource for anything and everything related to swine herd health...this edition does an outstanding job of keeping up with the advanced diagnostic technologies and the latest research on new or emerging diseases and syndromes...there is no other informational resource that comes close to providing the depth or quality of information on the topic of swine diseases as does this book"
Author: Leslie C. Sharkey
Publisher: John Wiley & Sons
ISBN: 1119125723
Category : Medical
Languages : en
Pages : 1027
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Book Description
This book offers a state-of-the-art, evidence-based reference to all aspects of veterinary cytology. Truly multidisciplinary in its approach, chapters are written by experts in fields ranging from clinical pathology to internal medicine, surgery, ophthalmology, and dermatology, drawing the various specialties together to create a comprehensive picture of cytology's role in diagnosis and treatment of animal disease. Firmly grounded in the primary literature, the book focuses on companion animals, with special chapters for species with fewer publications. Chapters are logically organized by body system, with additional chapters on tumors of particular import and diagnostic decision making. The first two sections of Veterinary Cytology focus on cytology techniques, quality control, and special laboratory techniques. Subsequent sections are organ/tissue-based and reflect what is known about the canine, feline, and equine species. This is followed by chapters on non-traditional species, including exotic companion mammals, rabbits, cattle, camelids, non-human primates, reptiles and birds, amphibians, fish, invertebrates, and sheep and goats. The last section highlights some unique features of the applications of cytology in industry settings. Provides a gold-standard reference to data-driven information about cytologic analysis in companion animal species Brings together authors from a wide range of specialties to present a thorough survey of cytology's use in veterinary medicine Offers broader species coverage and greater depth than any cytology reference currently available Veterinary Cytology is an essential resource for clinical and anatomic pathologists and any specialist in areas using cytology, including veterinary oncologists, criticalists, surgeons, ophthalmologists, dermatologists, and internists.
Author: Ross Farhadieh
Publisher: John Wiley & Sons
ISBN: 1118655427
Category : Medical
Languages : en
Pages : 1218
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Book Description
Plastic and reconstructive surgery continues to evolve as new techniques open up new possibilities for the surgeon. In this groundbreaking textbook, contemporary approaches are explained and demonstrated to allow trainee and experienced surgeons alike to understand and assimilate best practice. Containing over 300 outstanding color figures demonstrating surgical practice, an international cast of leading surgeons show the paths to effective plastic surgery technique and outcomes. They cover all the major bases including: Integument Pediatric Plastic Surgery Head and Neck Reconstruction The Breast Trunk, Lower Limb and Sarcomas Upper Limb and Hand Surgery Aesthetic Surgery Comprehensive in scope, practical in nature, Plastic and Reconstructive Surgery is your one-stop guide to successful surgical management of your patients. "This textbook is aimed at the trainee and young plastic surgeon, but it is extremely comprehensive and sufficiently detailed for any practitioner. The information is succinct, yet complete and up to date. . . . For a single-volume book, the detailed knowledge presented is impressive. . . . I think this is a great book. It is packed with good and up-to-date information, and I think it will be an invaluable resource for trainees but also for all plastic surgeons. The editors are to be congratulated on achieving a very difficult task with such success." —from a review by Peter C. Neligan, MB, in Plastic and Reconstructive Surgery "This is exactly what the editors of Plastic and reconstructive surgery: Approaches and Techniques set out to achieve in producing this excellent textbook. . . . It is truly an international effort at all levels, as the editors, from Australia (Ross D. Farhadieh), the UK (Neil W. Bulstrode) and Canada (Sabrina Cugno), have joined forces to recruit over 130 international contributors and produce a resource of over 1100 pages that provides a well-organized and thorough, yet succinct, text of the essentials of current plastic surgery. . . .Many of the contributors are world-renowned experts; however, there is also a new generation of young rising stars whose contributions are equally good, providing a new, fresh and contemporary feel." —from the Foreword by Julian J. Pribaz, Professor of Surgery, Harvard Medical School "The authors here have concentrated all this useful information into their chapters in a quite outstanding manner. Any plastic surgeon of whatever maturity will find this an excellent purchase which he/she will have no reason to regret." —from a review by Douglas H. Harrison in Journal of Plastic, Reconstructive & Aesthetic Surgery
