Author: Yun-Bo Shi
Publisher: Wiley-Liss
ISBN: 9780471244752
Category : Science
Languages : en
Pages : 292
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Book Description
In an age when advanced molecular and genetic tools allow studies in various systems, amphibian metamorphosis still offers perhaps the most accessible model for the study of postembryonic organogenesis and mechanisms of hormonal regulation during vertebrate development. Amphibian Metamorphosis: From Morphology to Molecular Biology integrates findings from the most recent research with earlier observations, providing molecular and mechanistic insights into the signal transduction pathways underlying tissue-specific transformations during metamorphosis. The author, renowned expert of anuran metamorphosis and Head of the Unit of Molecular Morphogenesis at NICHD/NIH, begins with an overview of metamorphosis in different classes of amphibians and various factors that influence this process. A review of earlier morphological, cellular, and biochemical changes focuses on organs and tissues that have been studied extensively at the molecular level, while discussion of the thyroid hormone signal transduction pathway emphasizes transcriptional regulation mechanisms by thyroid receptors. The book provides a summary and comparison of gene regulation programs induced by thyroid hormone in several organs that undergo distinct metamorphic transformations. Several chapters are devoted to functional and mechanistic implications of the molecular findings on the thyroid hormone response genes in tissue transformation. Special features of this book include: * An emphasis on integrating the morphological approach with molecularand cell biology * A historical perspective on the progression from discovery of the thyroid hormone to present-day research advances * Comparisons of amphibian and insect metamorphosis * Dozens of instructive photographs, several in full color Amphibian Metamorphosis: From Morphology to Molecular Biology is a unique and invaluable resource for professionals and aspiring professionals in develop-mental biology, molecular biology, cell biology, evolutionary biology, and endocrinology.
Author: OECD
Publisher: OECD Publishing
ISBN: 9264076247
Category :
Languages : en
Pages : 33
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Book Description
This Test Guideline describes an amphibian metamorphosis assay intended to screen substances which may interfere with the normal functioning of the hypothalamo-pituitary-thyroid axis. The assay was validated with the species Xenopus laevis, which is ...
Author: Harold Fox
Publisher: Springer Science & Business Media
ISBN: 1461253020
Category : Science
Languages : en
Pages : 303
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Book Description
This book came about as a result of a review I had written earlier on fea tures of cellular changes occurring during anuran metamorphosis. Only a limited treatment of this subject was possible in such a circumscribed work and only specific examples of organic change were dealt with. Thus the sins of omission weighed heavily, for so much information could not be included to provide a more comprehensive and authenticated account of the elaborate, complex, and far-reaching changes that an aquatic larva undergoes to become a terrestrial froglet. A good deal of my working life has been spent investigating amphib ians, especially their larval developmental morphology during metamor phosis, first at the level of light microscopy and in later years by electronmicroscopy. Initially I was particularly concerned with morpho logical homologies of a variety of larval structures, such as the cranial and pharyngeal skeleton and the nerves and musculature, in order to learn more about amphibian phylogeny, for during my pre-and early postgrad uate years G. R. Beer and D. M. S. Watson inspired an undying interest in and respect for vertebrate comparative anatomy. However, it now seems to be that amphibian phylogenetic relationships are best dealt with by the paleontologists, so ably demonstrated by D. M. S. Watson and A. S. Romer and the contemporary enthusiasts in this field like A. L. Panchen, R. L. Carroll, E. Jarvik, and K. S. Thompson among a host of others, particularly in the USA.
Author: Roy W. McDiarmid
Publisher: University of Chicago Press
ISBN: 9780226557625
Category : Nature
Languages : en
Pages : 476
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Book Description
In our own juvenile stage, many of us received our wide-eyed introduction to the wonders of nature by watching the metamorphosis of swimming tadpoles into leaping frogs and toads. The recent alarming declines in amphibian populations worldwide and the suitability of amphibians for use in answering research questions in disciplines as diverse as molecular systematics, animal behavior, and evolutionary biology have focused enormous attention on tadpoles. Despite this popular and scientific interest, relatively little is known about these fascinating creatures. In this indispensable reference, leading experts on tadpole biology relate what we currently know about tadpoles and what we might learn from them in the future. Tadpoles provides detailed summaries of tadpole morphology, development, behavior, ecology, and environmental physiology; explores the evolutionary consequences of the tadpole stage; synthesizes available information on their biodiversity; and presents a standardized terminology and an exhaustive literature review of tadpole biology.
Author: Carla Mucignat-Caretta
Publisher: CRC Press
ISBN: 1466553413
Category : Medical
Languages : en
Pages : 614
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Book Description
Intraspecific communication involves the activation of chemoreceptors and subsequent activation of different central areas that coordinate the responses of the entire organism—ranging from behavioral modification to modulation of hormones release. Animals emit intraspecific chemical signals, often referred to as pheromones, to advertise their presence to members of the same species and to regulate interactions aimed at establishing and regulating social and reproductive bonds. In the last two decades, scientists have developed a greater understanding of the neural processing of these chemical signals. Neurobiology of Chemical Communication explores the role of the chemical senses in mediating intraspecific communication. Providing an up-to-date outline of the most recent advances in the field, it presents data from laboratory and wild species, ranging from invertebrates to vertebrates, from insects to humans. The book examines the structure, anatomy, electrophysiology, and molecular biology of pheromones. It discusses how chemical signals work on different mammalian and non-mammalian species and includes chapters on insects, Drosophila, honey bees, amphibians, mice, tigers, and cattle. It also explores the controversial topic of human pheromones. An essential reference for students and researchers in the field of pheromones, this is also an ideal resource for those working on behavioral phenotyping of animal models and persons interested in the biology/ecology of wild and domestic species.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Hazel L. Sive
Publisher: CSHL Press
ISBN: 9780879695040
Category : Medical
Languages : en
Pages : 370
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Book Description
Amphibian embryos are supremely valuable in studies of early vertebrate development because they are large, handle easily, and can be obtained at many interesting stages. And of all the amphibians available for study, the most valuable is Xenopus laevis,which is easy to keep and ovulates at any time of year in response to simple hormone injections. Xenopusembryos have been studied for years but this is a particularly exciting time for the field. Techniques have become available very recently that permit a previously impossible degree of manipulation of gene expression in intact embryos, as well as the ability to visualize the results of such manipulation. As a result, a sophisticated new understanding of Xenopusdevelopment has emerged, which ensures the species’ continued prominent position among the organisms favored for biological investigation. This manual contains a comprehensive collection of protocols for the study of early development in Xenopusembryos. It is written by several of the field’s most prominent investigators in the light of the experience they gained as instructors in an intensive laboratory course taught at Cold Spring Harbor Laboratory since 1991. As a result it contains pointers, hints, and other technical knowledge not readily available elsewhere. This volume is essential reading for all investigators interested in the developmental and cell biology of Xenopusand vertebrates generally. Many of the techniques described here are illustrated in an accompanying set of videotapeswhich are cross-referenced to the appropriate section of the manual.
Author: Emil Witschi
Publisher:
ISBN:
Category : Embriología
Languages : en
Pages : 612
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Book Description
Author: Richard Marshall Eakin
Publisher: Univ of California Press
ISBN: 9780520003699
Category : Science
Languages : en
Pages : 284
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Book Description
Author: Institute of Laboratory Animal Resources (U.S.). Subcommittee on Amphibian Standards
Publisher: National Academies Press
ISBN: 030902210X
Category : Amphibians as laboratory animals
Languages : en
Pages : 166
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Book Description
