Planar Lipid Bilayers (BLM's) and Their Applications

Planar Lipid Bilayers (BLM's) and Their Applications PDF Author: H.T. Tien †
Publisher: Elsevier
ISBN: 0080539033
Category : Science
Languages : en
Pages : 1045

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Book Description
The lipid bilayer is the most basic structural element of cell membranes. A wide range of topics are covered in this volume, from the origin of the lipid bilayer concept, to current applications and experimental techniques. Each chapter in this volume is self-contained and describes a group's research, providing detailed methodology and key references useful for researchers. Lipid bilayer research is of great interest to many because of it's interdisciplinary nature.·Provides an overview of decades of research on the lipid bilayer·38 contributed chapters, by leading scientists, cover a wide range of topics in one authoritative volume·Book coincides with 40th anniversary of BLM

Planar Lipid Bilayers (BLM's) and Their Applications

Planar Lipid Bilayers (BLM's) and Their Applications PDF Author: H.T. Tien †
Publisher: Elsevier
ISBN: 0080539033
Category : Science
Languages : en
Pages : 1045

Get Book Here

Book Description
The lipid bilayer is the most basic structural element of cell membranes. A wide range of topics are covered in this volume, from the origin of the lipid bilayer concept, to current applications and experimental techniques. Each chapter in this volume is self-contained and describes a group's research, providing detailed methodology and key references useful for researchers. Lipid bilayer research is of great interest to many because of it's interdisciplinary nature.·Provides an overview of decades of research on the lipid bilayer·38 contributed chapters, by leading scientists, cover a wide range of topics in one authoritative volume·Book coincides with 40th anniversary of BLM

Bilayer Lipid Membranes (BLM)

Bilayer Lipid Membranes (BLM) PDF Author: H. Ti Tien
Publisher:
ISBN:
Category : Science
Languages : en
Pages : 680

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Book Description


Bilayer Lipid Membranes. Structure and Mechanical Properties

Bilayer Lipid Membranes. Structure and Mechanical Properties PDF Author: Tibor Hianik
Publisher: Springer Science & Business Media
ISBN: 0792335511
Category : Science
Languages : en
Pages : 452

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Book Description
In Bilayer Lipid Membranes. Structure and Mechanical Properties the authors use new methods of measurement, which they have themselves developed, to present an analysis of the relation between membrane structure and viscoelastic properties, in particular in the transversal direction. Hianik and Passechnik's approach is fundamentally different from the usual one, in that they analyze lipid bilayer dynamics during various modes of deformation, arriving at a new, `three-layer' model that accounts for the great heterogeneity of biomembranes. The macroscopic parameters of membranes have been measured using a wide variety of methods, leading to a discussion of the correlations between the parameters. There is also an extensive discussion of the dynamic changes in mechanical properties of lipid bilayers in the course of conformational transition of integral proteins. During the conformational changes of proteins, the structure of a bilayer undergoes a transition, reaching a new, stable membrane state. The book is the first to present a comprehensive analysis of long-distance interaction in lipid bilayers and of molecular mechanisms of mechanoreception. Audience: Scientists and graduate students working in biophysics, membranology, physiology, medicine, pharmacology, bioelectronics, electrochemistry, and colloid chemistry.

The Chlorophylls

The Chlorophylls PDF Author: Leo P. Vernon
Publisher: Academic Press
ISBN: 1483267725
Category : Science
Languages : en
Pages : 696

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Book Description
The Chlorophylls reviews developments in study of chlorophylls, and at the same time summarizes the state of knowledge in the more established areas of the physics, chemistry, and biology of chlorophylls. The book is organized into four sections. The first section deals with the chlorophylls as chemical entities, and treats their isolation, analysis, chemistry, and synthesis. The second concerns chlorophylls in real and colloidal solution and in the solid state in vitro, and includes the effects of aggregation on visible, infrared, and NMR spectral properties. The third section treats the biosynthesis, organization, and properties of chlorophylls in the plant and bacterial cell, and the fourth is concerned with the photochemical and photophysical behavior of chlorophylls in vitro and in vivo. It is hoped that this work will help those investigating selected aspects of chlorophyll to keep abreast of other methods and approaches, and will provide the interested scientist with a modern, conceptually organized treatment of the subject.

Electroporation and Electrofusion in Cell Biology

Electroporation and Electrofusion in Cell Biology PDF Author: C.A. Jordan
Publisher: Springer Science & Business Media
ISBN: 1489925287
Category : Science
Languages : en
Pages : 435

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Book Description
Cells can be funny. Try to grow them with a slightly wrong recipe, and they turn over and die. But hit them with an electric field strong enough to knock over a horse, and they do enough things to justify international meetings, to fill a sizable book, and to lead one to speak of an entirely new technology for cell manipulation. The very improbability of these events not only raises questions about why things happen but also leads to a long list of practical systems in which the application of strong electric fields might enable the merger of cell contents or the introduction of alien but vital material. Inevitably, the basic questions and the practical applications will not keep in step. The questions are intrinsically tough. It is hard enough to analyze the action of the relatively weak fields that rotate or align cells, but it is nearly impossible to predict responses to the cell-shredding bursts of electricity that cause them to fuse or to open up to very large molecular assemblies. Even so, theoretical studies and systematic examination of model systems have produced some creditable results, ideas which should ultimately provide hints of what to try next.

Thermal Biophysics of Membranes

Thermal Biophysics of Membranes PDF Author: Thomas Heimburg
Publisher: John Wiley & Sons
ISBN: 3527611606
Category : Science
Languages : en
Pages : 378

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Book Description
An overview of recent experimental and theoretical developments in the field of the physics of membranes, including new insights from the past decade. The author uses classical thermal physics and physical chemistry to explain our current understanding of the membrane. He looks at domain and 'raft' formation, and discusses it in the context of thermal fluctuations that express themselves in heat capacity and elastic constants. Further topics are lipid-protein interactions, protein binding, and the effect of sterols and anesthetics. Many seemingly unrelated properties of membranes are shown to be intimately intertwined, leading for instance to a coupling between membrane state, domain formation and vesicular shape. This also applies to non-equilibrium phenomena like the propagation of density pulses during nerve activity. Also included is a discussion of the application of computer simulations on membranes. For both students and researchers of biophysics, biochemistry, physical chemistry, and soft matter physics.

Bioelectrochemistry

Bioelectrochemistry PDF Author: Philip N. Bartlett
Publisher: John Wiley & Sons
ISBN: 0470753838
Category : Science
Languages : en
Pages : 494

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Book Description
Bioelectrochemistry: Fundamentals, Experimental Techniques and Application, covers the fundamental aspects of the chemistry, physics and biology which underlie this subject area. It describes some of the different experimental techniques that can be used to study bioelectrochemical problems and it describes various applications of biolelectrochemisty including amperometric biosensors, immunoassays, electrochemistry of DNA, biofuel cells, whole cell biosensors, in vivo applications and bioelectrosynthesis. By bringing together these different aspects, this work provides a unique source of information in this area, approaching the subject from a cross-disciplinary viewpoint.

Ion Channel Reconstitution

Ion Channel Reconstitution PDF Author: C. Miller
Publisher: Springer Science & Business Media
ISBN: 1475713614
Category : Science
Languages : en
Pages : 579

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Book Description
It is now over 30 years since the idea of ion-conducting pores burst on the elec trophysiological scene, 15 years since these were generalIy realized to be mem brane-spanning proteins, and 10 years since the first observations of single ion channels from higher organisms were made. During the past 5 years, several integral membrane channel proteins have been purified in a functionalIy competent state: the nicotinic acetylcholine receptor, the Na + channel, mitochondrial "VDAC," and a variety of porins. The stage is thus set to attack ion channels in the same ways that biochemists have been attacking enzymes for decades: isolation folIowed by functional analysis in as simple a system as possible, with a view towards understanding the molecular mechanisms ofthe protein's behavior and how this is related to the underlying molecular structure. This is always a daunting task, alI the more so with ion channels because of our still primitive and scanty understanding of channel structures and because of the difficulty in iso lating functionally active channel proteins. In this volume, which can be considered a biochemically slanted companion to Sakmann and Neher's Single-Channel Recording, I have tried to present a view of the current landscape of ion-channel reconstitution. These chapters illustrate not only the different approaches and techniques of the major practitioners of ion channel reconstitution but, as importantly, the varied motivations for doing this kind of work.

Biomembranes

Biomembranes PDF Author: Robert B. Gennis
Publisher: Springer Science & Business Media
ISBN: 1475720653
Category : Science
Languages : en
Pages : 549

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Book Description
New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermody namics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the graduate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases, the availability of texts in active research areas should help stimulate the creation of new courses.

Using Science to Improve the BLM Wild Horse and Burro Program

Using Science to Improve the BLM Wild Horse and Burro Program PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 0309264944
Category : Technology & Engineering
Languages : en
Pages : 399

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Book Description
Using Science to Improve the BLM Wild Horse and Burro Program: A Way Forward reviews the science that underpins the Bureau of Land Management's oversight of free-ranging horses and burros on federal public lands in the western United States, concluding that constructive changes could be implemented. The Wild Horse and Burro Program has not used scientifically rigorous methods to estimate the population sizes of horses and burros, to model the effects of management actions on the animals, or to assess the availability and use of forage on rangelands. Evidence suggests that horse populations are growing by 15 to 20 percent each year, a level that is unsustainable for maintaining healthy horse populations as well as healthy ecosystems. Promising fertility-control methods are available to help limit this population growth, however. In addition, science-based methods exist for improving population estimates, predicting the effects of management practices in order to maintain genetically diverse, healthy populations, and estimating the productivity of rangelands. Greater transparency in how science-based methods are used to inform management decisions may help increase public confidence in the Wild Horse and Burro Program.