Basic Mutagenicity Tests: IKEMS Recommended Procedures; UKEMS Sub-Committee on Guidelines for Mutagenicity Testing; Report; Part 1 Revised

Basic Mutagenicity Tests: IKEMS Recommended Procedures; UKEMS Sub-Committee on Guidelines for Mutagenicity Testing; Report; Part 1 Revised PDF Author: DJ Kirkland (Ed)
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Category :
Languages : en
Pages :

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Basic Mutagenicity Tests

Basic Mutagenicity Tests PDF Author: David J. Kirkland
Publisher: Cambridge University Press
ISBN: 9780521393478
Category : Medical
Languages : en
Pages : 164

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A summary of the essential texts that must be performed on all new compounds before they can be registered for use in the UK.

Supplementary Mutagenicity Tests

Supplementary Mutagenicity Tests PDF Author: David J. Kirkland
Publisher: Cambridge University Press
ISBN: 9780521450737
Category : Medical
Languages : en
Pages : 176

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Book Description
Originally published in 1993, this volume describes a complementary selection of tests to those described in the companion volume Basic Mutagenicity Tests (Cambridge University Press, 1990). These supplementary tests were used to assess risks of in vitro mutagenicity in those instances where the basic tests were inconclusive. As such, these tests had an important role in the assessment of the safety of compounds, drugs and chemicals. These supplementary test and guidelines, originally drawn up by the United Kingdom Environmental Mutagen Society (UKEMS) were fully revised in this publication to take full account of different regulatory guidelines and scientific advances. This volume will be of value to anyone with aninterest in regulatory affairs, mutagenicity testing and the registration of chemical products in the UK and Europe.

Supplementary Mutagenicity Tests

Supplementary Mutagenicity Tests PDF Author: United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing
Publisher: Cambridge University Press
ISBN: 052145073X
Category : Medical
Languages : en
Pages : 179

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Book Description
Originally published in 1993, this volume describes supplementary tests used to assess risks of in vitro mutagenicity when basic safety tests were inconclusive.

Report of the UKEMS Sub-committee on Guidelines for Mutagenicity Testing

Report of the UKEMS Sub-committee on Guidelines for Mutagenicity Testing PDF Author: United Kingdom Environmental Mutagen Society
Publisher:
ISBN:
Category : Mutagenicity testing
Languages : en
Pages : 178

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Statistical Evaluation of Mutagenicity Test Data

Statistical Evaluation of Mutagenicity Test Data PDF Author:
Publisher:
ISBN:
Category : Mutagenicity testing
Languages : en
Pages : 294

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Report of the UKEMS Sub-Committee on Guidelines for Mutagenicity Testing

Report of the UKEMS Sub-Committee on Guidelines for Mutagenicity Testing PDF Author: United Kingdom Environmental Mutagen Society. Sub-Committee on Guidelines for Mutagenicity Testing
Publisher:
ISBN: 9780950931814
Category : Mutagenicity testing
Languages : en
Pages : 260

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Basic Test Battery; Minimal Criteria; Professional Standards; Interpret

Basic Test Battery; Minimal Criteria; Professional Standards; Interpret PDF Author: B. J. Dean
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Category :
Languages : en
Pages :

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Report of the UKEMS Sub-committee on Guidelines for Mutagenicity Testing

Report of the UKEMS Sub-committee on Guidelines for Mutagenicity Testing PDF Author: United Kingdom Environmental Mutagen Society
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Genetic Toxicology

Genetic Toxicology PDF Author: James M. Parry
Publisher: Humana Press
ISBN: 9781617794209
Category : Medical
Languages : en
Pages : 433

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Book Description
The evaluation of potential mutagenic activity is a critical step in the assessment of the safety of both new and pre-existing chemical types. In Genetic Toxicology: Principles and Methods, expert contributors help to satisfy the demand for education in this tremendously important area of study. The volume covers three basic areas: the scientific basis of the discipline, the methodologies of the main test assays, and the application of the methods, all aimed primarily at scientists in the safety departments of the industries working with both natural and synthetic chemicals. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Intuitive and cutting-edge, Genetic Toxicology: Principles and Methods provides crucial support to both laboratory workers in providing quality information on the appropriate application of techniques and to study directors in their assay selection and protocol design in this vital field.