Bacterial Immunoglobulin–Binding Proteins PDF Download
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Author: Michael D. P. Boyle
Publisher: Academic Press
ISBN: 1483216535
Category : Medical
Languages : en
Pages : 494
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Book Description
Bacterial Immunoglobulin-Binding Proteins: Applications in Immunotechnology, Volume 2 covers the state of knowledge of bacterial immunoglobulin-binding proteins. The book focuses on practical approaches to isolation, characterization, and use of bacterial immunoglobulin-binding proteins. The majority of these studies involve the type I Fc-binding protein (staphylococcal protein A) and the type III Fc-binding protein (streptococcal protein G). Physiological chemists, pediatricians, and microbiologists will find the book invaluable.
Author: Michael D. P. Boyle
Publisher: Academic Press
ISBN: 1483216535
Category : Medical
Languages : en
Pages : 494
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Book Description
Bacterial Immunoglobulin-Binding Proteins: Applications in Immunotechnology, Volume 2 covers the state of knowledge of bacterial immunoglobulin-binding proteins. The book focuses on practical approaches to isolation, characterization, and use of bacterial immunoglobulin-binding proteins. The majority of these studies involve the type I Fc-binding protein (staphylococcal protein A) and the type III Fc-binding protein (streptococcal protein G). Physiological chemists, pediatricians, and microbiologists will find the book invaluable.
Author: Michael D.P. Boyle
Publisher: Academic Press
ISBN: 0323140580
Category : Medical
Languages : en
Pages : 430
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Book Description
Bacterial Immunoglobulin-Binding Proteins, Volume 1: Microbiology, Chemistry, and Biology investigates the immunoglobulin and Fc-binding proteins that have been isolated and characterized from a wide array of microorganisms, including protein A from staphylococcus and protein G from streptococcus. It examines the antigenic relationships among bacterial immunoglobulin-binding proteins, the immunoglobulin D-binding bacteria, the complement activation and bacterial immunoglobulin-binding proteins, the nature of the interaction of bacterial Fc receptors and immunoglobulin G, and the bacterial Fc receptors as putative virulence factors. Organized into 31 chapters, this volume begins with a historical overview of bacterial immunoglobulin-binding proteins, receptors for immunoglobulins, amino acid sequence of Fc receptors, and cloning of genes. It then discusses the staphylococcal protein A, including its biological activities and applications to immunotechnology. The book also explains the gene for staphylococcal protein A, immunoglobulin G Fc receptors of group A streptococci, and streptococcal protein G. It presents the structure and evolution of the streptococcal genes encoding protein G and interaction of bacterial immunoglobulin receptors with sites in the Fab region. It also discusses the lymphocyte stimulation by bacterial Fc receptors and cloning and expression of the beta protein gene of group B streptococci. The book concludes with a chapter on Fc receptors and the pathogenesis of bacterial infections in animals. This book will be of interest to biologists, microbiologists, chemists, and researchers working with immunoglobulin-binding proteins found in bacteria.
Author: Kenneth Murphy
Publisher: Garland Science
ISBN: 9780815344575
Category : Medical
Languages : en
Pages :
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Book Description
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author: Roald Nezlin
Publisher: Academic Press
ISBN: 008053452X
Category : Science
Languages : en
Pages : 292
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Book Description
This book provides comprehensive up-to-date information on the structure and function of immunoglobulins. It describes the basic features of these molecules, which assists the reader in understanding how they function as an integral part of the immune system. The Immunoglobulins describes the localization and structure of different binding sites of immunoglobulin molecules, including the antigen-binding site, on the basis of latest x-ray crystallography studies. It discusses recently developed biotechnological methods that allow scientists to obtain fully active antibody molecules in vitro even without immunization and to construct new variants of immunoglobulins and their fragments by fusing with various other active molecules. A survey of recent knowledge on immunoglobulin-binding molecules other than antigens and on flexibility of immunoglobulin molecules concludes the discussion of functional aspects of the problem. - Describes recent reviews on the structure and function of immunoglobulin molecules of various species - Summarizes in detail recent findings on the fine structure of the antigen-combining site - Presents comparative data on the antigen-recognizing sites of other molecules such as MHC proteins and T-cell receptors - Summarizes growing data on immunoglobulin binding sites responsible for the reaction of immunoglobulins with molecules other than antigens - Explores the rapid advance of recent biotechnological methods used for the construction of antibody molecules and their fragments with new properties - Presents extensive references and is lavishly illustrated
Author: Allan Matte
Publisher: Elsevier
ISBN: 0081030193
Category : Medical
Languages : en
Pages : 222
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Book Description
Approaches to the Purification, Analysis and Characterization of Antibody-Based Therapeutics provides the interested and informed reader with an overview of current approaches, strategies and considerations relating to the purification, analytics and characterization of therapeutic antibodies and related molecules. While there are obviously other books published in and around this subject area, they seem to be either older (c.a. year 2000 publication date) or are more limited in scope. The book will include an extensive bibliography of the published literature in the respective areas covered. It is not, however, intended to be a how-to methods book.
Author: Roland E. Kontermann
Publisher: Springer Science & Business Media
ISBN: 3642011446
Category : Medical
Languages : en
Pages : 770
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Book Description
Antibodies are indispensable tools for research, diagnosis, and therapy. Recombinant approaches allow the modification and improvement of nearly all antibody properties, such as affinity, valency, specificity, stability, serum half-life, effector functions, and immunogenicity. "Antibody Engineering" provides a comprehensive toolbox covering the well-established basics but also many exciting new techniques. The protocols reflect the latest "hands on" knowledge of key laboratories in this still fast-moving field. Newcomers will benefit from the proven step-by-step protocols, which include helpful practical advice; experienced antibody engineers will appreciate the new ideas and approaches. The book is an invaluable resource for all those engaged in antibody research and development.
Author:
Publisher: Academic Press
ISBN: 9780120342495
Category : Science
Languages : en
Pages : 536
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Book Description
Topics Covered Include: X-ray crystallography of ligands. Catalytic antibodies. Nature of the antigen. Antibody binding sites. Maturation of the immune response. Computational biochemistry of antibodies and T-cell receptors. Antigen-specific T-cell receptors and their reactions. Key Features * X-Ray Crystallography of Ligands * Catalytic Antibodies * Nature of the Antigen * Antibody Binding Sites * Maturtion of the Immune Response * Computational Biochemistry of Antibodies and * T-Cell Receptors * Antigen-Specific T-Cell Receptors and Their Reactions
Author: T. William Hutchens
Publisher: Springer Science & Business Media
ISBN: 1461525489
Category : Science
Languages : en
Pages : 295
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Book Description
Lactoferrin is an intriguing protein with an interesting structure and several known or suggested biological activities. We feel that attention on this protein has been too limited and diffuse, partly because it has been "hidden" among other well-known iron-binding proteins such as hemoglobin, ferritin and transferrin, but also perhaps because its biological functions are so diverse. Investigators that focus on lactoferrin represent a wide variety of medical and scientific disciplines that do not usually come together. It was our intention to improve that situation with this symposium. In this book, experts from a variety of disciplines describe the present knowledge of the structural features of lactoferrin, its carbohydrate side chains and its capacity to bind different metal ions and anions. Several of the possible physiological functions of lactoferrin are described in detail, including the role of lactoferrin in bacterial killing, its involvement in growth and proliferation, in immune function and in iron absorption. Aspects of the molecular biology of lactoferrin and its specific interactions with different cell types are also included. Finally, as lactoferrin now has become commercially available in larger quantities, possible industrial applications are discussed. The book should give the interested reader a thorough insight into our present knowledge of lactoferrin.
Author: Roland Kontermann
Publisher: John Wiley & Sons
ISBN: 3527328491
Category : Science
Languages : en
Pages : 373
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Book Description
For this ready reference, the internationally renowned authority in the field, Roland Kontermann, has assembled a team of outstanding contributors from industry and academia to convey the worldwide knowledge on modifying therapeutic proteins in order to optimize their pharmacological potential. The result is a comprehensive work covering all approaches and aspects of the topic in one handy volume, making this indispensable reading for companies and research institutions working on the development of biopharmaceuticals.
Author:
Publisher: Academic Press
ISBN: 0128021934
Category : Science
Languages : en
Pages : 663
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Book Description
Membrane Proteins – Engineering, Purification and Crystallization, a volume of Methods In Enzymology, encompasses chapters from the leading experts in the area of membrane protein biology. The chapters provide a brief overview of the topics covered and also outline step-by-step protocol for the interested audience. Illustrations and case example images are included wherever appropriate to help the readers understand the schematics and general experimental outlines. - Volume of Methods In Enzymology - Contains a collection of a diverse array of topics in the area of membrane protein biology ranging from recombinant expression, isolation, functional characterization, biophysical studies and crystallization
