Asymmetric Synthesis and NMR Studies of Chiral Lithium N,P-amide Complexes

Asymmetric Synthesis and NMR Studies of Chiral Lithium N,P-amide Complexes PDF Author: Petra Rönnholm
Publisher:
ISBN: 9789163368257
Category :
Languages : en
Pages : 73

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Asymmetric Synthesis and NMR Studies of Chiral Lithium N,P-amide Complexes

Asymmetric Synthesis and NMR Studies of Chiral Lithium N,P-amide Complexes PDF Author: Petra Rönnholm
Publisher:
ISBN: 9789163368257
Category :
Languages : en
Pages : 73

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Chiral Lithium Amides in Asymmetric Synthesis

Chiral Lithium Amides in Asymmetric Synthesis PDF Author: Per I. Arvidsson
Publisher:
ISBN: 9789162834678
Category :
Languages : en
Pages : 101

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Advances in Asymmetric Synthesis

Advances in Asymmetric Synthesis PDF Author: Alfred Hassner
Publisher: Elsevier
ISBN: 0080551998
Category : Science
Languages : en
Pages : 376

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Book Description
Enantioselective synthetic methods are not only in the forefront of chemical and pharmaceutical research but activity in this area is constantly increasing. It is stimulated by the urgency to obtain drugs or compounds of medicinal interest as single anantiomers, and the keeness to synthesize natural products in nonracemic form. This volume presents seven chapters from pioneers and authorities in this rapidly expanding field.

Asymmetric Synthesis Mediated by Chiral Lithium Amides

Asymmetric Synthesis Mediated by Chiral Lithium Amides PDF Author: Johan Granander
Publisher:
ISBN: 9789162866297
Category : Asymmetric synthesis
Languages : en
Pages : 65

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Chiral Auxiliaries and Ligands in Asymmetric Synthesis

Chiral Auxiliaries and Ligands in Asymmetric Synthesis PDF Author: J. Seyden-Penne
Publisher: Wiley-Interscience
ISBN:
Category : Science
Languages : en
Pages : 744

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Book Description
Table of Contents Preface Abbreviations Introduction 1 1 Enantiomerically Pure Chiral Auxiliaries 43 2 Chiral Reagents 87 3 Chiral Catalysis and Catalysts Bearing Chiral Ligands 117 4 Asymmetric Deprotonations and Protonations 143 5 Alkylations and Related Reactions 157 6 Additions to C=O and C=N Double Bonds 209 7 Additions to Carbon-Carbon Double Bonds 367 8 Additions to Double Bonds Bearing Heteroatoms. Oxidations of Sulfides and Selenides 503 9 Cycloadditions 513 10 Sigmatropic Rearrangements 593 11 Transition Metal Catalyzed Reactions 619 References 637 Index 707.

Asymmetric Synthesis of Non-Proteinogenic Amino Acids

Asymmetric Synthesis of Non-Proteinogenic Amino Acids PDF Author: Ashot S. Saghyan
Publisher: John Wiley & Sons
ISBN: 3527804471
Category : Science
Languages : en
Pages : 450

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Book Description
Authored by two internationally recognized experts with an excellent track record, this much-needed reference summarizes latest research in the rapidly developing field of stereoselective synthesis of enantiomerically enriched amino acids, particularly of non-proteinogenic origin. It highlights several different catalytic and stoichiometric asymmetric methods for their synthesis and also provides information on origin, biological properties, different synthetic strategies and important applications in medicine and pharmacology. Essential reading for synthetic chemists working in the field of asymmetric synthesis, natural products and peptide synthesis, stereochemistry, medicinal chemistry, biochemistry, pharmacology, and biotechnology.

Organolithiums in Enantioselective Synthesis

Organolithiums in Enantioselective Synthesis PDF Author: David M. Hodgson
Publisher: Springer Science & Business Media
ISBN: 3540001042
Category : Science
Languages : en
Pages : 325

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Book Description
This volume is the first dedicated to a comprehensive coverage of this rapidly developing transdisciplinary field. It provides a rich source of essential information on synthesizing molecules in an enantioselective manner using organolithiums, and serves as an inspiration for future developments.

Lithium Compounds in Organic Synthesis

Lithium Compounds in Organic Synthesis PDF Author: Renzo Luisi
Publisher: John Wiley & Sons
ISBN: 3527667539
Category : Science
Languages : en
Pages : 705

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Book Description
This unique book covers fundamentals of organolithium compounds and gives a comprehensive overview of the latest synthetic advances and developments in the field. Part I covers computational and spectroscopic aspects as well as structure-reactivity relationships of organolithiums, whereas Part II deals with new lithium-based synthetic methodologies as well as novel synthetic applications of functionalized lithium compounds. A useful resource for newcomers and active researchers involved in organic synthesis, whether working in academia or industry!

Axially Chiral Compounds

Axially Chiral Compounds PDF Author: Bin Tan
Publisher: John Wiley & Sons
ISBN: 3527347127
Category : Science
Languages : en
Pages : 338

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Book Description
Axially Chiral Compounds Explore this comprehensive and current volume summarizing the characteristics, synthesis, and applications of axial chirality Appearing widely in natural products, biologically active molecules, asymmetric chemistry, and material science, axially chiral motifs constitute the core backbones of the majority of chiral ligands and organocatalysts in asymmetric catalysis. In a new work of particular relevance to synthetic chemists, Axially Chiral Compounds: Asymmetric Synthesis and Applications delivers a clearly structured and authoritative volume covering the classification, characteristics, synthesis, and applications of axial chirality. A must read for every synthetic chemist practicing today, the book follows the development history, research status, and applications of axial chirality. An introductory chapter familiarizes the reader with foundational material before the distinguished authors describe the different classes and the synthesis of axial chiral compounds used in asymmetric synthesis. The book concludes with a focus on the applications of chiral ligands, chiral catalysts, and materials. Readers will also benefit from the inclusion of: A thorough introduction to asymmetric synthesis, including biaryls atropisomers, heterobiaryls atropisomers, and non-biaryls atropisomers Explorations of chiral allene, spiro skeletons, and natural products Practical discussions of asymmetric transformation, chiral ligands, and chiral catalysts An examination of miscellaneous applications of axially chiral compounds Perfect for organic chemists, chemists working with or on organometallics, catalytic chemists, and materials scientists, Axially Chiral Compounds: Asymmetric Synthesis and Applications will also earn a place in the libraries of natural products chemists who seek a one-stop reference for compounds exhibiting axial chirality.

Chiral Building Blocks in Asymmetric Synthesis

Chiral Building Blocks in Asymmetric Synthesis PDF Author: Jacek Wojaczynski
Publisher: John Wiley & Sons
ISBN: 3527834192
Category : Science
Languages : en
Pages : 692

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Book Description
Chiral Building Blocks in Asymmetric Synthesis A comprehensive introduction to the important classes of chiral building blocks Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks. In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. In Chiral Building Blocks in Asymmetric Synthesis readers will also find: Organization according to the most important compound classes — e.g. amino acids, BINOL and its derivatives, terpenes, and others — with an emphasis on synthesis and application A focus on the use of chiral building blocks for the preparation of bioactive compounds and supramolecular assemblies Chiral Building Blocks in Asymmetric Synthesis is a useful reference for organic chemists, catalytic chemists, chemists in industry, medicinal chemists, pharmaceutical chemists, and the libraries that support them.