Automated Insulin Delivery

Automated Insulin Delivery PDF Author: Dana M Lewis
Publisher: Independently Published
ISBN: 9781797763699
Category :
Languages : en
Pages : 164

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Book Description
Automated insulin delivery goes by many names: hybrid or full closed loop; artificial pancreas system (APS); "looping" and more. They are not all the same, though. You have choices, ranging from the type of pump body and CGM you want to use, to the algorithm and controller, to the interoperability and remote monitoring options, and more. Like switching from multiple daily injections to an insulin pump, switching from manual diabetes to automated insulin delivery has a learning curve. It's certainly one you can tackle. After all, you're already tackling type 1 diabetes! You already have the base knowledge and experience you need to succeed with a closed loop system, if it's right for you. But you might be wondering how to get ahead of your learning curve before you start or even choose an APS, or you've started and want to dig even deeper into optimizing how an automated insulin delivery system fits into your lifestyle. This book was written for you! It leverages the collective knowledge of the early adopters of do-it-yourself and commercial systems from the past five years and packages it into easy, understandable guides and lessons learned.In this book, you'll find new analogies to help you understand - and explain - this new method of diabetes management, and tips on how to communicate with your healthcare provider(s) about it. You'll see stories and examples from real families and individuals living with type 1 diabetes and how they benefit from artificial pancreas systems, and why they chose and continue to choose to use them. You'll be empowered to understand the basic components of artificial pancreas systems, how they work, and what questions to ask as you peruse your choices now and in the future. This book also includes a foreword by Aaron Kowalski, President and CEO of JDRF, and co-founder of the JDRF Artificial Pancreas Project. "I will immediately recommend this book not just to people looking to use a DIY closed loop system, but also to anybody looking to improve their grasp on the management of type 1 diabetes, whether patient, caregiver, or healthcare provider." - Aaron Neinstein, MD (Endocrinologist, UCSF)

Automated Insulin Delivery

Automated Insulin Delivery PDF Author: Dana M Lewis
Publisher: Independently Published
ISBN: 9781797763699
Category :
Languages : en
Pages : 164

Get Book Here

Book Description
Automated insulin delivery goes by many names: hybrid or full closed loop; artificial pancreas system (APS); "looping" and more. They are not all the same, though. You have choices, ranging from the type of pump body and CGM you want to use, to the algorithm and controller, to the interoperability and remote monitoring options, and more. Like switching from multiple daily injections to an insulin pump, switching from manual diabetes to automated insulin delivery has a learning curve. It's certainly one you can tackle. After all, you're already tackling type 1 diabetes! You already have the base knowledge and experience you need to succeed with a closed loop system, if it's right for you. But you might be wondering how to get ahead of your learning curve before you start or even choose an APS, or you've started and want to dig even deeper into optimizing how an automated insulin delivery system fits into your lifestyle. This book was written for you! It leverages the collective knowledge of the early adopters of do-it-yourself and commercial systems from the past five years and packages it into easy, understandable guides and lessons learned.In this book, you'll find new analogies to help you understand - and explain - this new method of diabetes management, and tips on how to communicate with your healthcare provider(s) about it. You'll see stories and examples from real families and individuals living with type 1 diabetes and how they benefit from artificial pancreas systems, and why they chose and continue to choose to use them. You'll be empowered to understand the basic components of artificial pancreas systems, how they work, and what questions to ask as you peruse your choices now and in the future. This book also includes a foreword by Aaron Kowalski, President and CEO of JDRF, and co-founder of the JDRF Artificial Pancreas Project. "I will immediately recommend this book not just to people looking to use a DIY closed loop system, but also to anybody looking to improve their grasp on the management of type 1 diabetes, whether patient, caregiver, or healthcare provider." - Aaron Neinstein, MD (Endocrinologist, UCSF)

Artificial Systems for Insulin Delivery

Artificial Systems for Insulin Delivery PDF Author: Paolo Brunetti
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 648

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Book Description


Advances in Artificial Pancreas Systems

Advances in Artificial Pancreas Systems PDF Author: Ali Cinar
Publisher: Springer
ISBN: 331972245X
Category : Technology & Engineering
Languages : en
Pages : 123

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Book Description
This brief introduces recursive modeling techniques that take account of variations in blood glucose concentration within and between individuals. It describes their use in developing multivariable models in early-warning systems for hypo- and hyperglycemia; these models are more accurate than those solely reliant on glucose and insulin concentrations because they can accommodate other relevant influences like physical activity, stress and sleep. Such factors also contribute to the accuracy of the adaptive control systems present in the artificial pancreas which is the focus of the brief, as their presence is indicated before they have an apparent effect on the glucose concentration and so can be more easily compensated. The adaptive controller is based on generalized predictive control techniques and also includes rules for changing controller parameters or structure based on the values of physiological variables. Simulation studies and clinical studies are reported to illustrate the performance of the techniques presented.

The Artificial Pancreas

The Artificial Pancreas PDF Author: Ricardo S. Sánchez-Peña
Publisher: Academic Press
ISBN: 0128156562
Category : Science
Languages : en
Pages : 308

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Book Description
The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient's quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results. - Focuses on Type 1 Diabetes Mellitus (T1DM) that is primarily found in children and typically treated by means of a syringe or insulin pump - Features research and results from top academic experimental groups, and from universities such as Harvard (USA), the University of Virginia (USA), the University of Padova (Italy), the University of Montpellier (France), and the Buenos Aires Institute of Technology (Argentina) - Discusses clinical trials of AP from around the world, including the United States, the EU, Latin America, and Israel

Artificial Insulin Delivery Systems

Artificial Insulin Delivery Systems PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Artificial Insulin Delivery Systems, Pancreas and Islet Transplantation

Artificial Insulin Delivery Systems, Pancreas and Islet Transplantation PDF Author: European Association for the Study of Diabetes. Study Group Artificial Insulin Delivery Systems, Pancreas and Islet Transplantation
Publisher:
ISBN:
Category :
Languages : en
Pages :

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Book Description


Technological Advances in the Treatment of Type 1 Diabetes

Technological Advances in the Treatment of Type 1 Diabetes PDF Author: D. Bruttomesso
Publisher: Karger Medical and Scientific Publishers
ISBN: 331802337X
Category : Medical
Languages : en
Pages : 274

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Book Description
The current epidemic of diabetes, obesity and related disorders is a driving force in the development of new technologies. Technological advances offer great new opportunities for the treatment of these chronic diseases. This review presents an update of developments that promise to revolutionize the treatment of diabetes. It examines hospital and outpatient care, intensive insulin therapy, blood glucose monitoring and innovative steps towards the construction of an artificial pancreas. Providing a comprehensive overview on the latest advances, this volume of Frontiers in Diabetes will be of particular interest to all healthcare providers involved in the daily management of patients with diabetes or related diseases.

Artificial Insulin Delivery Systems, Pancreas and Islet Transplantation

Artificial Insulin Delivery Systems, Pancreas and Islet Transplantation PDF Author: European Association for the Study of Diabetes Study Group Artificial Insulin Delivery Systems, Pancreas and Islet Transplantation
Publisher:
ISBN:
Category :
Languages : en
Pages : 128

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Book Description


Cost-effectiveness of hybrid closed-loop artificial pancreas systems in patients with type 1 diabetes

Cost-effectiveness of hybrid closed-loop artificial pancreas systems in patients with type 1 diabetes PDF Author: Kim Vanessa Enders
Publisher: GRIN Verlag
ISBN: 3346640493
Category : Medical
Languages : en
Pages : 68

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Book Description
Master's Thesis from the year 2022 in the subject Health - Digital Health Management, grade: 1.0, University College London, language: English, abstract: This paper is about the cost-effectiveness of hybrid closed-loop artificial pancreas systems in patients with type 1 diabetes. Advances in diabetes technology over the past decade have culminated in the commercialization of hybrid closed-loop (HCL) artificial pancreas systems, alleviating the onus of self-management in type 1 diabetes (T1D). Clinical effectiveness benefits over conventional systems are well-documented. However, no systematic review has been performed on the cost-effectiveness of HCL systems, even if health economic assessments are integral to guide policy decisions. To perform a systematic review, critical analysis, and narrative synthesis of available economic evaluations of HCL systems for T1D patients and upcoming cost-effectiveness studies within the research pipeline. A systematic search was conducted following the PRISMA 2020 guidelines in MEDLINE, Embase, and CENTRAL via Ovid in October 2021. A review of trial registries and grey literature, as well as reference list and forward citation search, complemented the search. Predefined eligibility criteria were used. Retrieved studies underwent CHEERS-based quality assessment. Data were subsequently extracted via a standardized data extraction form. Results were presented through narrative synthesis, dominance ranking framework, and display of standardized ICERs (in 2021 GBP) in a cost-effectiveness plane. Of the 213 records retrieved via systematic review and 331 identified through other search methods, 8 were included in the review and 11 in the research pipeline. Overall, included studies demonstrated good quality. Standardized ICERs ranged from 5,688 to 30,293 GBP per QALY gained. Limitations of included evidence were discussed in detail and contain lack of long-term effectiveness data and inter-system comparisons, as well as possible conflicts of interest. Overall results suggest cost-effectiveness for HCL systems compared to current treatment standards such as CSII, CGM, and SAP. Additional high-quality, large scale, and long-term economic research is required to assess health economic outcomes for HCL technology in clinical practice. This thesis provides fundamental starting points in the research pipeline as a basis of further research.

Personalized Predictive Modeling in Type 1 Diabetes

Personalized Predictive Modeling in Type 1 Diabetes PDF Author: Eleni I. Georga
Publisher: Academic Press
ISBN: 0128051469
Category : Computers
Languages : en
Pages : 253

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Book Description
Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures. Describes fundamentals of modeling techniques as applied to glucose control Covers model selection process and model validation Offers computer code on a companion website to show implementation of models and algorithms Features the latest developments in the field of diabetes predictive modeling