Author: Robert Edward Bossio
Publisher:
ISBN:
Category : Electrospray ionization mass spectrometry
Languages : en
Pages : 444
Book Description
Applying Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry to Structural Problems in Inorganic and Biochemistry
Author: Robert Edward Bossio
Publisher:
ISBN:
Category : Electrospray ionization mass spectrometry
Languages : en
Pages : 444
Book Description
Publisher:
ISBN:
Category : Electrospray ionization mass spectrometry
Languages : en
Pages : 444
Book Description
Applied Electrospray Mass Spectrometry
Author: Birendra N. Pramanik
Publisher: CRC Press
ISBN: 1135560439
Category : Science
Languages : en
Pages : 478
Book Description
Discussing strategies to determine the structure and machanisms of numerous compound classics, this book covers new chemical and elctrophoretic techniques for rapid sample preconcentration and separation. It summarizes breakthroughs in the theory and instrumentation of electrospray mass spectrometry in pharmaceutical and biomedical applications, provides practical examples for the characterization of peptides, proteins, and glycoproteins, includes applications in proteomics, combinatorial chemistry, and drug characterization. Topics include chemical and electrophoretic techniques for rapid sample preconcentration and separation, screening processes for proteins from libraries of compounds, protein folding and dynamics, and more.
Publisher: CRC Press
ISBN: 1135560439
Category : Science
Languages : en
Pages : 478
Book Description
Discussing strategies to determine the structure and machanisms of numerous compound classics, this book covers new chemical and elctrophoretic techniques for rapid sample preconcentration and separation. It summarizes breakthroughs in the theory and instrumentation of electrospray mass spectrometry in pharmaceutical and biomedical applications, provides practical examples for the characterization of peptides, proteins, and glycoproteins, includes applications in proteomics, combinatorial chemistry, and drug characterization. Topics include chemical and electrophoretic techniques for rapid sample preconcentration and separation, screening processes for proteins from libraries of compounds, protein folding and dynamics, and more.
Biochemical Applications of Electrospray Ionization Coupled with Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Author: Philip Spencer Green
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
Book Description
Fundamentals and Applications of Fourier Transform Mass Spectrometry
Author: Philippe Schmitt-Kopplin
Publisher: Elsevier
ISBN: 0128140143
Category : Science
Languages : en
Pages : 780
Book Description
Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. - Covers FT-ICR-MS and Orbitrap's fundamentals, enhancing researcher knowledge - Includes details on ion sources, data processing, chemical analysis and imaging - Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis
Publisher: Elsevier
ISBN: 0128140143
Category : Science
Languages : en
Pages : 780
Book Description
Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. - Covers FT-ICR-MS and Orbitrap's fundamentals, enhancing researcher knowledge - Includes details on ion sources, data processing, chemical analysis and imaging - Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis
FT-ICR/MS
Author: Bruce Asamoto
Publisher: Wiley-VCH
ISBN:
Category : Fourier transform spectroscopy
Languages : en
Pages : 326
Book Description
Publisher: Wiley-VCH
ISBN:
Category : Fourier transform spectroscopy
Languages : en
Pages : 326
Book Description
Internal and External Source Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Author: Ragulan Ramanathan
Publisher:
ISBN: 9780530004860
Category : Science
Languages : en
Pages : 290
Book Description
Abstract: Design, development, and coupling of an electrospray ionization (ESI) source with a Fourier Transform Ion Cyclotron (FTICR) Mass Spectrometer (MS). Developed ESI source was used for detection and characterization of small and large molecules. Dissertation Discovery Company and University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "Internal and External Source Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry" by Ragulan Ramanathan, was obtained from University of Florida and is being sold with permission from the author. A digital copy of this work may also be found in the university's institutional repository, IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.
Publisher:
ISBN: 9780530004860
Category : Science
Languages : en
Pages : 290
Book Description
Abstract: Design, development, and coupling of an electrospray ionization (ESI) source with a Fourier Transform Ion Cyclotron (FTICR) Mass Spectrometer (MS). Developed ESI source was used for detection and characterization of small and large molecules. Dissertation Discovery Company and University of Florida are dedicated to making scholarly works more discoverable and accessible throughout the world. This dissertation, "Internal and External Source Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry" by Ragulan Ramanathan, was obtained from University of Florida and is being sold with permission from the author. A digital copy of this work may also be found in the university's institutional repository, IR@UF. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation.
Dissertation Abstracts International
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 812
Book Description
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 812
Book Description
Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Study of Singly and Doubly Charged Organometallic Complexes
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 42
Book Description
An external source electrospray ionization (ESI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometer has been used to study the organometallic complexes Ag2(DPM)2(BF4)2 (where DPM = bis-diphenylphosphino- methane), Ag2(DPM)3(BF4)2 and Ru(II)(bp)3(PF6)2 (where bpy = 2,2'-bipyridyl). The high mass resolution and accurate mass assignment of parent and collisionally induced dissociation (CID) fragment ions provided structural information on these organometallic complexes. CID in the capillary/skimmer region and inside the FTICR analyzer cell were performed on these complexes and results from each type of experiment were compared. Important fragmentation pathways and reaction types, including bond cleavage, ligand loss, and ligand substitution were identified. Electrospray ionization, Organometallic complexes, Fourier transform ion cyclotron resonance mass spectrometry.
Publisher:
ISBN:
Category :
Languages : en
Pages : 42
Book Description
An external source electrospray ionization (ESI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometer has been used to study the organometallic complexes Ag2(DPM)2(BF4)2 (where DPM = bis-diphenylphosphino- methane), Ag2(DPM)3(BF4)2 and Ru(II)(bp)3(PF6)2 (where bpy = 2,2'-bipyridyl). The high mass resolution and accurate mass assignment of parent and collisionally induced dissociation (CID) fragment ions provided structural information on these organometallic complexes. CID in the capillary/skimmer region and inside the FTICR analyzer cell were performed on these complexes and results from each type of experiment were compared. Important fragmentation pathways and reaction types, including bond cleavage, ligand loss, and ligand substitution were identified. Electrospray ionization, Organometallic complexes, Fourier transform ion cyclotron resonance mass spectrometry.
American Doctoral Dissertations
Author:
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 776
Book Description
Publisher:
ISBN:
Category : Dissertation abstracts
Languages : en
Pages : 776
Book Description
Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry in Biological Applications
Author: Huan He
Publisher:
ISBN:
Category :
Languages : en
Pages : 121
Book Description
ABSTRACT: Chapter 2 describes various aspects of a developed method for polar lipid semi-quantification. Simple liquid-liquid extraction and one-step nano-LC separation are important for analyses of complex cellular lipid mixtures -- We observed more than 20 fold increases in detected lipid species after nano-LC separation. This method was applied on glioma cell lines, U87, under different combination of gene-/chemotherapy. Combination of adenovirus wt-p53 transfection and topoisomerase inhibition results in cells' G2 arrest and apoptosis. A sugar binding protein, galectin-1, was down-regulated under such treatment. Lipidomics study identified the associated changes in the polar lipidome - the decrease of short chain asialo-GM1 (a ligand of galectin-1), decreases of long chain gangliosides, increases of short chain sulfatides and increases of all phospholipids, especially hydroxylated phospholipids.
Publisher:
ISBN:
Category :
Languages : en
Pages : 121
Book Description
ABSTRACT: Chapter 2 describes various aspects of a developed method for polar lipid semi-quantification. Simple liquid-liquid extraction and one-step nano-LC separation are important for analyses of complex cellular lipid mixtures -- We observed more than 20 fold increases in detected lipid species after nano-LC separation. This method was applied on glioma cell lines, U87, under different combination of gene-/chemotherapy. Combination of adenovirus wt-p53 transfection and topoisomerase inhibition results in cells' G2 arrest and apoptosis. A sugar binding protein, galectin-1, was down-regulated under such treatment. Lipidomics study identified the associated changes in the polar lipidome - the decrease of short chain asialo-GM1 (a ligand of galectin-1), decreases of long chain gangliosides, increases of short chain sulfatides and increases of all phospholipids, especially hydroxylated phospholipids.