Applications of Regression Models in Epidemiology

Applications of Regression Models in Epidemiology PDF Author: Erick Suárez
Publisher: John Wiley & Sons
ISBN: 1119212502
Category : Mathematics
Languages : en
Pages : 272

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Book Description
A one-stop guide for public health students and practitioners learning the applications of classical regression models in epidemiology This book is written for public health professionals and students interested in applying regression models in the field of epidemiology. The academic material is usually covered in public health courses including (i) Applied Regression Analysis, (ii) Advanced Epidemiology, and (iii) Statistical Computing. The book is composed of 13 chapters, including an introduction chapter that covers basic concepts of statistics and probability. Among the topics covered are linear regression model, polynomial regression model, weighted least squares, methods for selecting the best regression equation, and generalized linear models and their applications to different epidemiological study designs. An example is provided in each chapter that applies the theoretical aspects presented in that chapter. In addition, exercises are included and the final chapter is devoted to the solutions of these academic exercises with answers in all of the major statistical software packages, including STATA, SAS, SPSS, and R. It is assumed that readers of this book have a basic course in biostatistics, epidemiology, and introductory calculus. The book will be of interest to anyone looking to understand the statistical fundamentals to support quantitative research in public health. In addition, this book: • Is based on the authors’ course notes from 20 years teaching regression modeling in public health courses • Provides exercises at the end of each chapter • Contains a solutions chapter with answers in STATA, SAS, SPSS, and R • Provides real-world public health applications of the theoretical aspects contained in the chapters Applications of Regression Models in Epidemiology is a reference for graduate students in public health and public health practitioners. ERICK SUÁREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. He received a Ph.D. degree in Medical Statistics from the London School of Hygiene and Tropical Medicine. He has 29 years of experience teaching biostatistics. CYNTHIA M. PÉREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. She received an M.S. degree in Statistics and a Ph.D. degree in Epidemiology from Purdue University. She has 22 years of experience teaching epidemiology and biostatistics. ROBERTO RIVERA is an Associate Professor at the College of Business at the University of Puerto Rico at Mayaguez. He received a Ph.D. degree in Statistics from the University of California in Santa Barbara. He has more than five years of experience teaching statistics courses at the undergraduate and graduate levels. MELISSA N. MARTÍNEZ is an Account Supervisor at Havas Media International. She holds an MPH in Biostatistics from the University of Puerto Rico and an MSBA from the National University in San Diego, California. For the past seven years, she has been performing analyses for the biomedical research and media advertising fields.

Applications of Regression Models in Epidemiology

Applications of Regression Models in Epidemiology PDF Author: Erick Suárez
Publisher: John Wiley & Sons
ISBN: 1119212502
Category : Mathematics
Languages : en
Pages : 272

Get Book

Book Description
A one-stop guide for public health students and practitioners learning the applications of classical regression models in epidemiology This book is written for public health professionals and students interested in applying regression models in the field of epidemiology. The academic material is usually covered in public health courses including (i) Applied Regression Analysis, (ii) Advanced Epidemiology, and (iii) Statistical Computing. The book is composed of 13 chapters, including an introduction chapter that covers basic concepts of statistics and probability. Among the topics covered are linear regression model, polynomial regression model, weighted least squares, methods for selecting the best regression equation, and generalized linear models and their applications to different epidemiological study designs. An example is provided in each chapter that applies the theoretical aspects presented in that chapter. In addition, exercises are included and the final chapter is devoted to the solutions of these academic exercises with answers in all of the major statistical software packages, including STATA, SAS, SPSS, and R. It is assumed that readers of this book have a basic course in biostatistics, epidemiology, and introductory calculus. The book will be of interest to anyone looking to understand the statistical fundamentals to support quantitative research in public health. In addition, this book: • Is based on the authors’ course notes from 20 years teaching regression modeling in public health courses • Provides exercises at the end of each chapter • Contains a solutions chapter with answers in STATA, SAS, SPSS, and R • Provides real-world public health applications of the theoretical aspects contained in the chapters Applications of Regression Models in Epidemiology is a reference for graduate students in public health and public health practitioners. ERICK SUÁREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. He received a Ph.D. degree in Medical Statistics from the London School of Hygiene and Tropical Medicine. He has 29 years of experience teaching biostatistics. CYNTHIA M. PÉREZ is a Professor of the Department of Biostatistics and Epidemiology at the University of Puerto Rico School of Public Health. She received an M.S. degree in Statistics and a Ph.D. degree in Epidemiology from Purdue University. She has 22 years of experience teaching epidemiology and biostatistics. ROBERTO RIVERA is an Associate Professor at the College of Business at the University of Puerto Rico at Mayaguez. He received a Ph.D. degree in Statistics from the University of California in Santa Barbara. He has more than five years of experience teaching statistics courses at the undergraduate and graduate levels. MELISSA N. MARTÍNEZ is an Account Supervisor at Havas Media International. She holds an MPH in Biostatistics from the University of Puerto Rico and an MSBA from the National University in San Diego, California. For the past seven years, she has been performing analyses for the biomedical research and media advertising fields.

Applied Survival Analysis

Applied Survival Analysis PDF Author: David W. Hosmer, Jr.
Publisher: John Wiley & Sons
ISBN: 1118211588
Category : Mathematics
Languages : en
Pages : 285

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Book Description
THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING TIME-TO-EVENT DATA—NOW IN A VALUABLE NEW EDITION Since publication of the first edition nearly a decade ago, analyses using time-to-event methods have increase considerably in all areas of scientific inquiry mainly as a result of model-building methods available in modern statistical software packages. However, there has been minimal coverage in the available literature to9 guide researchers, practitioners, and students who wish to apply these methods to health-related areas of study. Applied Survival Analysis, Second Edition provides a comprehensive and up-to-date introduction to regression modeling for time-to-event data in medical, epidemiological, biostatistical, and other health-related research. This book places a unique emphasis on the practical and contemporary applications of regression modeling rather than the mathematical theory. It offers a clear and accessible presentation of modern modeling techniques supplemented with real-world examples and case studies. Key topics covered include: variable selection, identification of the scale of continuous covariates, the role of interactions in the model, assessment of fit and model assumptions, regression diagnostics, recurrent event models, frailty models, additive models, competing risk models, and missing data. Features of the Second Edition include: Expanded coverage of interactions and the covariate-adjusted survival functions The use of the Worchester Heart Attack Study as the main modeling data set for illustrating discussed concepts and techniques New discussion of variable selection with multivariable fractional polynomials Further exploration of time-varying covariates, complex with examples Additional treatment of the exponential, Weibull, and log-logistic parametric regression models Increased emphasis on interpreting and using results as well as utilizing multiple imputation methods to analyze data with missing values New examples and exercises at the end of each chapter Analyses throughout the text are performed using Stata® Version 9, and an accompanying FTP site contains the data sets used in the book. Applied Survival Analysis, Second Edition is an ideal book for graduate-level courses in biostatistics, statistics, and epidemiologic methods. It also serves as a valuable reference for practitioners and researchers in any health-related field or for professionals in insurance and government.

Regression Models as a Tool in Medical Research

Regression Models as a Tool in Medical Research PDF Author: Werner Vach
Publisher: CRC Press
ISBN: 1466517484
Category : Mathematics
Languages : en
Pages : 497

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Book Description
While regression models have become standard tools in medical research, understanding how to properly apply the models and interpret the results is often challenging for beginners. Regression Models as a Tool in Medical Research presents the fundamental concepts and important aspects of regression models most commonly used in medical research, including the classical regression model for continuous outcomes, the logistic regression model for binary outcomes, and the Cox proportional hazards model for survival data. The text emphasizes adequate use, correct interpretation of results, appropriate presentation of results, and avoidance of potential pitfalls. After reviewing popular models and basic methods, the book focuses on advanced topics and techniques. It considers the comparison of regression coefficients, the selection of covariates, the modeling of nonlinear and nonadditive effects, and the analysis of clustered and longitudinal data, highlighting the impact of selection mechanisms, measurement error, and incomplete covariate data. The text then covers the use of regression models to construct risk scores and predictors. It also gives an overview of more specific regression models and their applications as well as alternatives to regression modeling. The mathematical details underlying the estimation and inference techniques are provided in the appendices.

Regression Modeling with Actuarial and Financial Applications

Regression Modeling with Actuarial and Financial Applications PDF Author: Edward W. Frees
Publisher: Cambridge University Press
ISBN: 0521760119
Category : Business & Economics
Languages : en
Pages : 585

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Book Description
This book teaches multiple regression and time series and how to use these to analyze real data in risk management and finance.

Regression Methods in Biostatistics

Regression Methods in Biostatistics PDF Author: Eric Vittinghoff
Publisher: Springer Science & Business Media
ISBN: 1461413524
Category : Education
Languages : en
Pages : 526

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Book Description
This fresh edition, substantially revised and augmented, provides a unified, in-depth, readable introduction to the multipredictor regression methods most widely used in biostatistics. The examples used, analyzed using Stata, can be applied to other areas.

Exposure Assessment in Environmental Epidemiology

Exposure Assessment in Environmental Epidemiology PDF Author: Mark J. Nieuwenhuijsen
Publisher: Oxford University Press, USA
ISBN: 0199378789
Category : Medical
Languages : en
Pages : 417

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Book Description
Preceded by Exposure assessment in occupational and environmental epidemiology / edited by Mark J. Nieuwenhuijsen. 1st ed. 2003.

The Cox Model and Its Applications

The Cox Model and Its Applications PDF Author: Mikhail Nikulin
Publisher: Springer
ISBN: 3662493322
Category : Mathematics
Languages : en
Pages : 124

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Book Description
This book will be of interest to readers active in the fields of survival analysis, genetics, ecology, biology, demography, reliability and quality control. Since Sir David Cox’s pioneering work in 1972, the proportional hazards model has become the most important model in survival analysis. The success of the Cox model stimulated further studies in semiparametric and nonparametric theories, counting process models, study designs in epidemiology, and the development of many other regression models that could offer more flexible or more suitable approaches in data analysis. Flexible semiparametric regression models are increasingly being used to relate lifetime distributions to time-dependent explanatory variables. Throughout the book, various recent statistical models are developed in close connection with specific data from experimental studies in clinical trials or from observational studies.

Regression

Regression PDF Author: Ludwig Fahrmeir
Publisher: Springer Science & Business Media
ISBN: 3642343333
Category : Business & Economics
Languages : en
Pages : 768

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Book Description
The aim of this book is an applied and unified introduction into parametric, non- and semiparametric regression that closes the gap between theory and application. The most important models and methods in regression are presented on a solid formal basis, and their appropriate application is shown through many real data examples and case studies. Availability of (user-friendly) software has been a major criterion for the methods selected and presented. Thus, the book primarily targets an audience that includes students, teachers and practitioners in social, economic, and life sciences, as well as students and teachers in statistics programs, and mathematicians and computer scientists with interests in statistical modeling and data analysis. It is written on an intermediate mathematical level and assumes only knowledge of basic probability, calculus, and statistics. The most important definitions and statements are concisely summarized in boxes. Two appendices describe required matrix algebra, as well as elements of probability calculus and statistical inference.

Medical Applications of Finite Mixture Models

Medical Applications of Finite Mixture Models PDF Author: Peter Schlattmann
Publisher: Springer Science & Business Media
ISBN: 3540686517
Category : Medical
Languages : en
Pages : 252

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Book Description
Patients are not alike! This simple truth is often ignored in the analysis of me- cal data, since most of the time results are presented for the “average” patient. As a result, potential variability between patients is ignored when presenting, e.g., the results of a multiple linear regression model. In medicine there are more and more attempts to individualize therapy; thus, from the author’s point of view biostatis- cians should support these efforts. Therefore, one of the tasks of the statistician is to identify heterogeneity of patients and, if possible, to explain part of it with known explanatory covariates. Finite mixture models may be used to aid this purpose. This book tries to show that there are a large range of applications. They include the analysis of gene - pression data, pharmacokinetics, toxicology, and the determinants of beta-carotene plasma levels. Other examples include disease clustering, data from psychophysi- ogy, and meta-analysis of published studies. The book is intended as a resource for those interested in applying these methods.

An Integrative Metaregression Framework for Descriptive Epidemiology

An Integrative Metaregression Framework for Descriptive Epidemiology PDF Author: Abraham D. Flaxman
Publisher:
ISBN: 9780295991849
Category : Epidemiology
Languages : en
Pages : 0

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Book Description
To provide the tools and knowledge needed in efforts to improve the health of the world's populations, researchers collaborated on the Global Burden of Diseases, Injuries, and Risk Factors Study 2010. The study produced comprehensive estimates of over 200 diseases and health risk factors in 187 countries over two decades, results that will be used by governments and non-governmental agencies to inform priorities for global health research, policies, and funding. Integrated Meta-Regression Framework for Descriptive Epidemiology is the first book-length treatment of model-based meta-analytic methods for descriptive epidemiology used in the Global Burden of Disease Study 2010. In addition to collecting the prior work on compartmental modeling of disease, this book significantly extends the model, by formally connecting the system dynamics model of disease progression to a statistical model of epidemiological rates and demonstrates how the two models were combined to allow researchers to integrate relevant data. Practical applications of the model to meta-analysis of more than a dozen different diseases complement the theoretical foundations of the integrative systems modeling of disease in populations. The book concludes with a detailed description of the future directions for research in model-based meta-analysis of descriptive epidemiological data. Abraham Flaxman is assistant professor of global health in the Institute for Health Metrics and Evaluation at the University of Washington.