Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 8
Book Description
Antiviral substances (including interferon).
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 8
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 8
Book Description
Antiviral Drugs and Interferon: The Molecular Basis of Their Activity
Author: Yechiel Becker
Publisher: Springer Science & Business Media
ISBN: 1461338042
Category : Medical
Languages : en
Pages : 452
Book Description
Research on antiviral drugs and their mode of action in infected cells. in animals and in man. has led to a better understanding of the molecular pro cesses involved in virus replication. Screeninq of large numbers of natural and semisynthetic compounds resulted in the characterization of certain sub stances that had a limited efficiency as antiviral druqs. A few chemically synthesized compounds were also found to be effective as antiviral agents in the chemotherapy of human virus diseases. A major difficulty in the develop ment of effective antiviral agents has been the lack of selectivity. and toxicity for uninfected cells. of drugs that effectively inhibited virus replication in vitro. Further understanding of the molecular processes of virus replication in infected cells has resulted in the development of new antivirals directed at virus-coded enzymes or proteins. Recent studies on antivirals that are activated by the herpes simplex virus type l-coded thy midine kinase from a prod rug to an antiviral drug have opened new directions in the development of effective antiviral drugs. The present book deals with a number of antiviral drugs effective against herpes simplex viruses and provides some insight into the molecular aspects of virus replication. It also throws light on the new approaches to the development of antiviral drugs. The molecular basis of the antiviral activity of new and known drugs and their possible use in chemotherapy of viral disease are presented in this book.
Publisher: Springer Science & Business Media
ISBN: 1461338042
Category : Medical
Languages : en
Pages : 452
Book Description
Research on antiviral drugs and their mode of action in infected cells. in animals and in man. has led to a better understanding of the molecular pro cesses involved in virus replication. Screeninq of large numbers of natural and semisynthetic compounds resulted in the characterization of certain sub stances that had a limited efficiency as antiviral druqs. A few chemically synthesized compounds were also found to be effective as antiviral agents in the chemotherapy of human virus diseases. A major difficulty in the develop ment of effective antiviral agents has been the lack of selectivity. and toxicity for uninfected cells. of drugs that effectively inhibited virus replication in vitro. Further understanding of the molecular processes of virus replication in infected cells has resulted in the development of new antivirals directed at virus-coded enzymes or proteins. Recent studies on antivirals that are activated by the herpes simplex virus type l-coded thy midine kinase from a prod rug to an antiviral drug have opened new directions in the development of effective antiviral drugs. The present book deals with a number of antiviral drugs effective against herpes simplex viruses and provides some insight into the molecular aspects of virus replication. It also throws light on the new approaches to the development of antiviral drugs. The molecular basis of the antiviral activity of new and known drugs and their possible use in chemotherapy of viral disease are presented in this book.
Interferon and Antiviral Substances Bibliography from MEDLARS.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 234
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 234
Book Description
Antiviral Substances (including Interferon).
Author: National Institute of Allergy and Infectious Diseases (U.S.)
Publisher:
ISBN:
Category :
Languages : en
Pages : 6
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 6
Book Description
Antiviral Chemotherapy, Interferons and Vaccines
Author: David O. White
Publisher:
ISBN:
Category : Antiviral agents
Languages : en
Pages : 128
Book Description
Publisher:
ISBN:
Category : Antiviral agents
Languages : en
Pages : 128
Book Description
Antiviral Substances (including Interferon)
Author:
Publisher:
ISBN:
Category : Interferon
Languages : en
Pages : 6
Book Description
Publisher:
ISBN:
Category : Interferon
Languages : en
Pages : 6
Book Description
The Interferon System
Author: W.E. Stewart II
Publisher: Springer Science & Business Media
ISBN: 3709134323
Category : Medical
Languages : en
Pages : 432
Book Description
This book is an update of Interferon, published in 1969 by Dr. Jan Vilcek. The field of interferon research has since expanded from its former narrow treatment of interferon strictly as an antiviral substance, such that The Interferon System now encompasses cellular modulations ranging from immune alterations to cell proliferative restrictions to antitumor activities. The steadily increasing number of these non-antiviral functions of interferons emphasizes the need for a comprehensive - and critical - review of the entire literature of interferon studies. The text, with its supporting bibliography, provides complete coverage of interferon research. A newcomer to the area should find here all the informa tion necessary to understand why interferon, which has been studied for more than twenty years and which originally stirred excitement over its clinical pros pects, is still inspiring speculation about this potential. For those already fa miliar with the seemingly perpetual clinical promise of interferon, this volume should serve as a valuable reference source, the largest bibliography on the subject ever to appear under one cover. Clearly, this book should be considered only as an introduction to the topic and as a reference source; most questions about the interferon system are still unanswered - even unasked. Hopefully this summation and critical evalua tion of work done to date will stimulate and facilitate further progress. William E. Stewart II New York, N. Y., February 1979 Contents I. Introduction ............................................................. .
Publisher: Springer Science & Business Media
ISBN: 3709134323
Category : Medical
Languages : en
Pages : 432
Book Description
This book is an update of Interferon, published in 1969 by Dr. Jan Vilcek. The field of interferon research has since expanded from its former narrow treatment of interferon strictly as an antiviral substance, such that The Interferon System now encompasses cellular modulations ranging from immune alterations to cell proliferative restrictions to antitumor activities. The steadily increasing number of these non-antiviral functions of interferons emphasizes the need for a comprehensive - and critical - review of the entire literature of interferon studies. The text, with its supporting bibliography, provides complete coverage of interferon research. A newcomer to the area should find here all the informa tion necessary to understand why interferon, which has been studied for more than twenty years and which originally stirred excitement over its clinical pros pects, is still inspiring speculation about this potential. For those already fa miliar with the seemingly perpetual clinical promise of interferon, this volume should serve as a valuable reference source, the largest bibliography on the subject ever to appear under one cover. Clearly, this book should be considered only as an introduction to the topic and as a reference source; most questions about the interferon system are still unanswered - even unasked. Hopefully this summation and critical evalua tion of work done to date will stimulate and facilitate further progress. William E. Stewart II New York, N. Y., February 1979 Contents I. Introduction ............................................................. .
Viral Interference and Interferon
Author: R. D. Andrews
Publisher: Elsevier
ISBN: 1483192768
Category : Science
Languages : en
Pages : 101
Book Description
Viral Interference and Interferon details the developments in the control of virus infections by natural means. The book is comprised of eight chapters that discuss various aspects of interferon. The text first introduces the main concepts of the subject matter. The succeeding chapter discusses various concerns about interferon, including the production, nature, mechanisms, and mode of actions. The book also covers interferon in humans and animals, and its significance. The text will be of great use to students of microbiology, virology, genetics, and immunology.
Publisher: Elsevier
ISBN: 1483192768
Category : Science
Languages : en
Pages : 101
Book Description
Viral Interference and Interferon details the developments in the control of virus infections by natural means. The book is comprised of eight chapters that discuss various aspects of interferon. The text first introduces the main concepts of the subject matter. The succeeding chapter discusses various concerns about interferon, including the production, nature, mechanisms, and mode of actions. The book also covers interferon in humans and animals, and its significance. The text will be of great use to students of microbiology, virology, genetics, and immunology.
Progress in the Development and Use of Antiviral Drugs and Interferon
Author: WHO Expert Committee on Onchocerciasis
Publisher:
ISBN: 9789241207522
Category : Animals as carriers of disease
Languages : en
Pages : 91
Book Description
Publisher:
ISBN: 9789241207522
Category : Animals as carriers of disease
Languages : en
Pages : 91
Book Description
Interferons
Author: Carlo Aul
Publisher: Springer Science & Business Media
ISBN: 3642604110
Category : Medical
Languages : en
Pages : 302
Book Description
Interferons were among the first cytokines to be studied clinically in recombinant form in the 1980s, beginning a new era of pharmacotherapy in internal medicine. Interferons were soon employed in the treatment of tumors and it was shown that those hematopoietic neoplasias which had been difficult to treat with chemotherapy responded well to interferon treatment. In the present volume, renowned international authors update the importance of interferons in various fields of internal medicine, dermatology, and urology. The book also contains a general introduction into the classification, structure, and mode of action of interferons. Further chapters discuss the range of side effects of these substances and point out possible focuses of further clinical interferon research.
Publisher: Springer Science & Business Media
ISBN: 3642604110
Category : Medical
Languages : en
Pages : 302
Book Description
Interferons were among the first cytokines to be studied clinically in recombinant form in the 1980s, beginning a new era of pharmacotherapy in internal medicine. Interferons were soon employed in the treatment of tumors and it was shown that those hematopoietic neoplasias which had been difficult to treat with chemotherapy responded well to interferon treatment. In the present volume, renowned international authors update the importance of interferons in various fields of internal medicine, dermatology, and urology. The book also contains a general introduction into the classification, structure, and mode of action of interferons. Further chapters discuss the range of side effects of these substances and point out possible focuses of further clinical interferon research.