Therapeutic Antibodies

Therapeutic Antibodies PDF Author: Yuti Chernajovsky
Publisher: Springer
ISBN: 9783540732587
Category : Medical
Languages : en
Pages : 380

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Book Description
This essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes.

Therapeutic Antibodies

Therapeutic Antibodies PDF Author: Yuti Chernajovsky
Publisher: Springer
ISBN: 9783540732587
Category : Medical
Languages : en
Pages : 380

Get Book Here

Book Description
This essential work, edited by two researchers at London’s famous Queen Mary’s medical school targets one of the most important areas in medical development today. These days, antibody therapeutics are the treatment of choice for several autoimmune and oncological conditions. They are, indeed, becoming the molecules of choice for further combination therapies and cell engineering. In this timely work, a slew of expert in the field of drug development summarize all the current developments and clinical successes.

Management of Diabetic Retinopathy

Management of Diabetic Retinopathy PDF Author: F. Bandello
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318060429
Category : Medical
Languages : en
Pages : 206

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Book Description
Recently developed diagnostic and therapeutic technologies such as OCT-angiography and small gauge vitrectomy have influenced the modern treatment of diabetic retinopathy. This volume provides a summary of the state-of-the-art evidence-based approach to managing complications that may occur with diabetic retinopathy. It offers the latest information on pathogenesis and diagnosis, and highly experienced clinicians review the results of relevant randomized clinical trials that serve as the basis of current therapy. The book provides not only a summary of data from randomized trials but also an analysis and interpretation by internationally renowned experts. Ophthalmology residents, fellows, and practicing clinicians will find this book to be a useful reference when seeking evidence-based treatment strategies for various complications of diabetic retinopathy. It is also for researchers identifying new avenues of drug developments and for insurance professionals and health care policy administrators who are establishing evidence-based therapy guidelines for therapeutic intervention.

Physiologic and Pathologic Angiogenesis

Physiologic and Pathologic Angiogenesis PDF Author: Dan Simionescu
Publisher: BoD – Books on Demand
ISBN: 9535130234
Category : Medical
Languages : en
Pages : 466

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Book Description
The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all.

Intravitreal Steroids

Intravitreal Steroids PDF Author: Albert J. Augustin
Publisher: Springer
ISBN: 3319144871
Category : Medical
Languages : en
Pages : 113

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Book Description
This book explains how to use intravitreal steroids optimally in the management of patients with intraocular inflammation (uveitis) and macular edema. The rationale for this treatment approach is first explained by examining the pathophysiology of these disease entities, with particular attention to the major role of inflammatory processes. Devices for the delivery of steroids to the eye are discussed, and guidance provided on the role of imaging studies before, during, and after steroid therapy. The value of different steroidal approaches is then considered in detail. Other topics addressed include the use of steroids as a surgical adjunct and within a combination strategy. Uveitis and macular edema are common sight-threatening diseases or complications of diabetes and retinal vein occlusion for which no adequate treatment was available until recently. Both trainees and practitioners will find Intravitreal Steroids to be an invaluable aid in combating these blinding diseases.

Ocular Vascular Occlusive Disorders

Ocular Vascular Occlusive Disorders PDF Author: Sohan Singh Hayreh
Publisher: Springer
ISBN: 3319127810
Category : Medical
Languages : en
Pages : 863

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Book Description
This book provides a comprehensive account of the pathogenesis, clinical features, and management of ocular vascular occlusive disorders, with the focus very much on the scientific evidence. This offers a sound basis for addressing the many controversies that surround these disorders, which collectively constitute the most common cause of visual impairment or blindness. The book is divided into two sections, the first of which addresses the basic science and encompasses vascular anatomy, blood supply and flow, and retinal tolerance time to acute ischemia. The second, clinical, section covers the presentation, clinical features, diagnosis, and treatment of the full range of vascular occlusive disorders of the retina, the choroid, the anterior segment of the eye, ophthalmic manifestations of carotid artery disease and the optic nerve. Ocular Vascular Occlusive Disorders, written by a distinguished world leader in the field, will be invaluable for general ophthalmologists, and particularly for retina specialists, neuro-ophthalmologists, and researchers.

Ophthalmic Literature

Ophthalmic Literature PDF Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 184

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Book Description


Retinal and Choroidal Angiogenesis

Retinal and Choroidal Angiogenesis PDF Author: John Penn
Publisher: Springer Science & Business Media
ISBN: 1402067801
Category : Medical
Languages : en
Pages : 567

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Book Description
This book provides a comprehensive, in-depth review of our current understanding of the growth of blood vessels within the eye. Novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye. The book emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance.

Ocular Angiogenesis

Ocular Angiogenesis PDF Author: Joyce Tombran-Tink
Publisher: Springer Science & Business Media
ISBN: 1597450472
Category : Medical
Languages : sr
Pages : 409

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Book Description
Leading academic and pharmaceutical researchers and clinicians from many disciplines synthesize and summarize current clinical and basic knowledge concerning abnormal growth of blood vessels in the eye, the cause of major neovascular eye diseases. The authors also identify and assess the most promising approaches with potential for commercial exploitation and discuss the challenges encountered in developing therapeutics for ocular neovascular diseases. Highlights include illuminating chapters on gene therapy and novel drug delivery systems and excellent summaries of the newest therapeutic approaches.

Microincision Vitrectomy Surgery

Microincision Vitrectomy Surgery PDF Author: H. Oh
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318026611
Category : Medical
Languages : en
Pages : 262

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Book Description
Over the last two decades, tremendous progress has been made in vitrectomy surgery, most importantly the significant reduction of the gauge and implementation of microincision vitrectomy surgery (MIVS). At the same time, the introduction of wide-viewing systems and the utilization of vital dyes to better recognize structures like the vitreous and membranes have taken place. This volume starts with the fundamentals of MIVS, introducing both the mechanics and the physics of the latest generation of vitrectomy devices, followed by a description of the discrete gauge systems (i.e. 23-, 25-, and 27-gauge). Individualized but mandatory settings, techniques, and technology are also discussed in detail. There are also more than ten chapters outlining concrete surgical strategies that give surgeons a thorough overview of the procedures.

Retinal Gene Therapy

Retinal Gene Therapy PDF Author: Camiel J.F. Boon
Publisher: Humana Press
ISBN: 9781493975211
Category : Medical
Languages : en
Pages : 380

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Book Description
This detailed volume describes a spectrum of methods and protocols that can be used for the bench-to-bedside development and evaluation of retinal gene therapy. Methods for the successful delivery of these gene therapy vector systems to the retina are examined, as well as assays to test the efficacy in vitro in cell cultures, for gene augmentation and gene editing in vivo on rodents, pigs, and monkey retinas, and on human retinal explants as well as in human clinical studies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Retinal Gene Therapy: Methods and Protocols provides a wide range of readers from students to research experts with vital information on ocular gene therapy vector technology, in vitro and in vivo biological assays, and clinical protocols, to promote further studies for the benefit of children and adults with inherited retinal disease.