Anti-Estrogen Regulations of Macrophage Products that Influence Breast Cancer Cell Proliferation and Susceptibility to Apoptosis PDF Download
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Languages : en
Pages : 8
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Book Description
In June 2006, I applied for a final no-cost extension to complete Task 2c of the project which required more time than previously anticipated. Program was slow owing to difficulty in recruiting a qualified laboratory technician for a single year. During the spring and summer (2006). I trained an undergraduate student, Ms. Giaelle Burnett, who is now assisting me with cell culture, western blotting and RT-PCR. The project will be completed in the current year (06/07).
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 8
Get Book Here
Book Description
In June 2006, I applied for a final no-cost extension to complete Task 2c of the project which required more time than previously anticipated. Program was slow owing to difficulty in recruiting a qualified laboratory technician for a single year. During the spring and summer (2006). I trained an undergraduate student, Ms. Giaelle Burnett, who is now assisting me with cell culture, western blotting and RT-PCR. The project will be completed in the current year (06/07).
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Category :
Languages : en
Pages : 23
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Book Description
Macrophage function can be regulated by breast cancer cells to sustain an inflammatory microenvironment that promotes cancer cell proliferation and survival. MCF-7 cells suppress IL-10 expression by co-cultured macrophages. Activated and resting THP-1 macrophages were able to induce SNAIL expression in MCF-7 cells. SNAIL has been implicated in the epithelial-mesenchymal transition which precedes metastasis. These observations suggest that tumor-associated macrophages may promote progression-related gene expression at discrete steps in the progression cascade. Both Faslodex(TradeMark) and tamoxifen were effective in up-regulating pigment epithelium-derived factor, a potent anti-angiogenic cytokine, and in down-regulating SNAIL in MCF-7 cells.
Author: Bharat B. Aggarwal
Publisher: Springer
ISBN: 3034808372
Category : Medical
Languages : en
Pages : 489
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Book Description
This volume examines in detail the role of chronic inflammatory processes in the development of several types of cancer. Leading experts describe the latest results of molecular and cellular research on infection, cancer-related inflammation and tumorigenesis. Further, the clinical significance of these findings in preventing cancer progression and approaches to treating the diseases are discussed. Individual chapters cover cancer of the lung, colon, breast, brain, head and neck, pancreas, prostate, bladder, kidney, liver, cervix and skin as well as gastric cancer, sarcoma, lymphoma, leukemia and multiple myeloma.
Author: Sabra L. Klein
Publisher: Springer Nature
ISBN: 3031351398
Category : Medical
Languages : en
Pages : 282
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Book Description
This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents. This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).
Author: Dil Afroze
Publisher: BoD – Books on Demand
ISBN: 1789239613
Category : Medical
Languages : en
Pages : 127
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Book Description
This book offers a comprehensive overview of recent developments in the field of breast cancer biology. It is a complete and descriptive reference on motioning pathways and new treatment options for the future transnational scientists and clinicians working on cancer research and treatment. We greatly appreciate the work of all the contributors to this book. They have brought with them tremendous diversity of perspectives and fields, which is truly reflective of the complexity of the topic, and they have come together in this project to serve as the node of multidisciplinary collaboration in this field. Finally, we must acknowledge the thousands of cancer patients who have participated in the studies, and who have inspired us to gather information to significantly progress knowledge in the field in recent years.
Author: Adriano Rossi
Publisher: Springer Science & Business Media
ISBN: 376437506X
Category : Medical
Languages : en
Pages : 246
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Book Description
This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.
Author: Albert Altchek
Publisher: Elsevier
ISBN: 008049451X
Category : Medical
Languages : en
Pages : 595
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Book Description
This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders.KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine
Author: Yearul Kabir
Publisher: Academic Press
ISBN: 0128161515
Category : Health & Fitness
Languages : en
Pages : 522
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Book Description
Functional Foods in Cancer Prevention and Therapy presents the wide range of functional foods associated with the prevention and treatment of cancer. In recent decades, researchers have made progress in our understanding of the association between functional food and cancer, especially as it relates to cancer treatment and prevention. Specifically, substantial evidence from epidemiological, clinical and laboratory studies show that various food components may alter cancer risk, the prognosis after cancer onset, and the quality of life after cancer treatment. The book documents the therapeutic roles of well-known functional foods and explains their role in cancer therapy. The book presents complex cancer patterns and evidence of the effective ways to control cancers with the use of functional foods. This book will serve as informative reference for researchers focused on the role of food in cancer prevention and physicians and clinicians involved in cancer treatment. Discusses the role of functional foods in cancer therapy Presents research-based evidence of the role of herbs and bioactive foods in cancer treatment and prevention Provides the most current, concise, scientific information regarding the efficacy of functional foods in preventing cancer and improving the quality of life Explores antioxidants, phytochemicals, nutraceuticals, herbal medicine and supplements in relation to cancer prevention and treatment Contains a clinical approach to the use of functional foods to prevent and treat cancer Emphasizes the role and mechanism of functional foods, including the characterization of active compounds on cancer prevention and treatment
Author: C. Wayne Bardin
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 488
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Book Description
Author: A. Pinchera
Publisher: Springer Science & Business Media
ISBN: 146130945X
Category : Medical
Languages : en
Pages : 579
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Book Description
In 1956, three groups independently reported evidence that some thyroid disease appearing spontaneously in humans or experimentally induced in animals are related to autoimmune processes. The interval between these landmark discoveries and the present has witnessed a remarkable and continuing growth of both knowledge and concepts concerning the mechanisms of immune regulation, the pathogenesis of autoimmune thyroid diseases, and their clinical and laboratory manifestations. More importantly knowledge of thyroid autoimmunity has, in many respects, comprised the vanguard of an ever increasing appreciation and understanding of autoimmune diseases in general. On November 24-26 1986, an International Symposium on Thyroid Autoimmunity was held in Pisa. Its purpose was to commemorate the birth of thyroid autoimmunity as a scientific discipline, to summarize current knowledge and concepts in this area, and where possible, to anticipate areas of opportunity for the future - hence the theme of the Symposium, Memories and Perspectives. To open the meeting, the Magnifico Rettore (Chancellor) of the University of Pisa granted special Awards to Dr. Deborah Doniach, Dr. Ivan Roitt, and Dr. Noel R. Rose, who published the first fundamental studies in the field of thyroid autoimmunity, and to Dr. Duncan G. Adams, whose discovery of the long-acting thyroid stimulator (LATS) opened the door to our current understanding of the pathogenesis of Graves' disease. During the meeting thirty plenary lectures were presented.
