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Author: Kenneth Joel Shapiro
Publisher: Seattle, [Wash.] ; Toronto : Hogrefe & Huber
ISBN:
Category : Medical
Languages : en
Pages : 352
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Book Description
After surveying current research practices and model development strategies, the author examines animal models of eating disorders from both scientific and ethical points of view. He exposes logical inconsistencies in the study of animals as models for human behavior, and concludes that such research has little to contribute. The foreword is by noted chimpanzee-researcher Jane Goodall. Annotation copyrighted by Book News, Inc., Portland, OR
Author: Kenneth Joel Shapiro
Publisher: Seattle, [Wash.] ; Toronto : Hogrefe & Huber
ISBN:
Category : Medical
Languages : en
Pages : 352
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Book Description
After surveying current research practices and model development strategies, the author examines animal models of eating disorders from both scientific and ethical points of view. He exposes logical inconsistencies in the study of animals as models for human behavior, and concludes that such research has little to contribute. The foreword is by noted chimpanzee-researcher Jane Goodall. Annotation copyrighted by Book News, Inc., Portland, OR
Author: Nicole C. Nelson
Publisher: University of Chicago Press
ISBN: 022654611X
Category : Science
Languages : en
Pages : 262
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Book Description
Mice are used as model organisms across a wide range of fields in science today—but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or anxiety. How do scientists convince funders, fellow scientists, the general public, and even themselves that animal experiments are a good way of producing knowledge about the genetics of human behavior? In Model Behavior, Nicole C. Nelson takes us inside an animal behavior genetics laboratory to examine how scientists create and manage the foundational knowledge of their field. Behavior genetics is a particularly challenging field for making a clear-cut case that mouse experiments work, because researchers believe that both the phenomena they are studying and the animal models they are using are complex. These assumptions of complexity change the nature of what laboratory work produces. Whereas historical and ethnographic studies traditionally portray the laboratory as a place where scientists control, simplify, and stabilize nature in the service of producing durable facts, the laboratory that emerges from Nelson’s extensive interviews and fieldwork is a place where stable findings are always just out of reach. The ongoing work of managing precarious experimental systems means that researchers learn as much—if not more—about the impact of the environment on behavior as they do about genetics. Model Behavior offers a compelling portrait of life in a twenty-first-century laboratory, where partial, provisional answers to complex scientific questions are increasingly the norm.
Author: P. Michael Conn
Publisher: Academic Press
ISBN: 0124159125
Category : Science
Languages : en
Pages : 1109
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Book Description
Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. - Organized by disease orientation for ease of searchability - Provides information on locating resources, animal alternatives and animal ethics - Covers a broad range of animal models used in research for human disease
Author: Kurt Leroy Hoffman
Publisher: Woodhead Publishing
ISBN: 0081001061
Category : Medical
Languages : en
Pages : 325
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Book Description
Modeling Neuropsychiatric Disorders in Laboratory Animals serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals interested in the use of animal models in preclinical research related to human neuropsychiatric disorders. The text focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders. Chapters contain discussions on both classical and modern views on the validation of animal models for neuropsychiatric disorders, also discussing the utility of endophenotypes in modeling neuropsychiatric disease. Subsequent chapters deal with four specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders. Final sections discuss the future for the development, validation, and use of animal models in basic and preclinical research. - Focuses on the rationale and theory of using animal behavior, both pathological and normal, as a tool for understanding the neural underpinnings of neuropsychiatric disorders - Serves as a guide for students and basic investigators in the fields of behavioral sciences, psychology, neuroscience, psychiatry, and other professionals - Discusses specific classes of disorders, including anxiety disorders, depressive disorders, obsessive-compulsive and related disorders
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309252113
Category : Science
Languages : en
Pages : 102
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Book Description
Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop.
Author: Kenneth L Davis
Publisher:
ISBN: 9781950192908
Category :
Languages : en
Pages : 160
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Book Description
Animal Emotions: How They Drive Human Behavior gives a concise overview of ancient mammalian emotions deeply rooted in the human brain. Jaak Panksepp, a world-renowned neuroscientist, dedicated his life career to the study of mammalian emotions and he carved out seven distinct emotional systems he called seeking, lust, care, and play (positive emotions), and fear, anger, and sadness (negative emotions), all exerting a tremendous influence on human behavior.Christian Montag, a neuroscientist and psychologist, and a long-time collaborator of Jaak Panksepp, revisits together with Kenneth L. Davis, one of Jaak's PhD students, Panksepp's theories and provides the reader with new insights into the nature of emotions and their role as survival tools, both for animals and for humans. They also raise new questions about the background of the research field Jaak Panksepp coined "Affective Neuroscience." How are personality and psychopathology linked to animal emotions? Do animals feel the same way as we do? What are our emotional needs in a digital society, and what is key to a happy life?
Author: George Serban
Publisher: Springer Science & Business Media
ISBN: 1468421840
Category : Science
Languages : en
Pages : 297
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Book Description
In March, 1974, an International Symposium was held at the Harmonie Club in New York to discuss a highly pertinent problem in today's research: the "Rele vance of the Animal Psychopathological Model to the Human." This meeting was sponsored by the Kittay Foundation, which brought together an outstanding group of scientists involved in widely different fields of research. This volume, it is hoped, will convey the tone of lively and cordial exchange between inter nationally renowned investigators, including Dr. I. Eibl-Eibesfeldt from Germany, Dr. Robert A. Hinde from England, Dr. Edward F. Domino from Michigan, and Dr. Pierre Pichot from France, Chairman of the Steering Committee. In his welcoming address, Mr. Sol Kittay reminded us that man has achieved remarkable control over his environment but not over himself, and he suggested that we should reexamine our ancestral origins, and search in animal behavior for clues to the understanding of normal and abnormal behavior in man.
Author: Florian Holsboer
Publisher: Springer Science & Business Media
ISBN: 9783540225683
Category : Medical
Languages : en
Pages : 588
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Book Description
The present volume gives a comprehensive overview on the current state of basic and clinical research on Anxiety and Anxiolytic Drugs. Using newly developed methods and techniques researchers are now beginning to understand the molecular mechanisms of anxiety, anxiety disorders and their treatment. In parallel, new drug targets have been generated and the first clinical studies with new compounds have been started. In 20 chapters written by numerous experts in the field comprehensive information on all relevant topics is provided.
Author: Jerry J. Buccafusco
Publisher: CRC Press
ISBN: 1420041819
Category : Medical
Languages : en
Pages : 341
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Book Description
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic
Author:
Publisher: Academic Press
ISBN: 012816574X
Category : Medical
Languages : en
Pages : 228
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Book Description
Cellular and Animal Models in Human Genomics Research provides an indispensable resource for applying comparative genomics in the annotation of disease-gene associated variants that are identified by human genomic sequencing. The book presents a thorough overview of effective protocols for the use of cellular and animal modeling methods to turn lists of plausible genes into causative biomarkers. With chapters written by international experts, the book first addresses the fundamental aspects of using cellular and animal models in genetic and genomic studies, including in-depth examples of specific models and their utility, i.e., yeast, worms, flies, fish, mice and large animals. Protocols for properly conducting model studies, genomic technology, modeling candidate genes vs. genetic variants, integrative modeling, utilizing induced pluripotent stem cells, and employing CRISPR-Cas9 are also discussed in-depth. - Provides a thorough, accessible resource that helps researchers and students employ cellular and animal models in their own genetic and genomic studies - Offers guidance on how to effectively interpret the results and significance of genetic and genomic model studies for human health - Features chapters from international experts in the use of specific cellular and animal models, including yeast, worms, flies, fish, mice, and large animals, among other organisms
