Model Behavior

Model Behavior PDF Author: Nicole C. Nelson
Publisher: University of Chicago Press
ISBN: 022654611X
Category : Science
Languages : en
Pages : 262

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Book Description
Mice are used as model organisms across a wide range of fields in science today—but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or anxiety. How do scientists convince funders, fellow scientists, the general public, and even themselves that animal experiments are a good way of producing knowledge about the genetics of human behavior? In Model Behavior, Nicole C. Nelson takes us inside an animal behavior genetics laboratory to examine how scientists create and manage the foundational knowledge of their field. Behavior genetics is a particularly challenging field for making a clear-cut case that mouse experiments work, because researchers believe that both the phenomena they are studying and the animal models they are using are complex. These assumptions of complexity change the nature of what laboratory work produces. Whereas historical and ethnographic studies traditionally portray the laboratory as a place where scientists control, simplify, and stabilize nature in the service of producing durable facts, the laboratory that emerges from Nelson’s extensive interviews and fieldwork is a place where stable findings are always just out of reach. The ongoing work of managing precarious experimental systems means that researchers learn as much—if not more—about the impact of the environment on behavior as they do about genetics. Model Behavior offers a compelling portrait of life in a twenty-first-century laboratory, where partial, provisional answers to complex scientific questions are increasingly the norm.

Model Behavior

Model Behavior PDF Author: Nicole C. Nelson
Publisher: University of Chicago Press
ISBN: 022654611X
Category : Science
Languages : en
Pages : 262

Get Book Here

Book Description
Mice are used as model organisms across a wide range of fields in science today—but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or anxiety. How do scientists convince funders, fellow scientists, the general public, and even themselves that animal experiments are a good way of producing knowledge about the genetics of human behavior? In Model Behavior, Nicole C. Nelson takes us inside an animal behavior genetics laboratory to examine how scientists create and manage the foundational knowledge of their field. Behavior genetics is a particularly challenging field for making a clear-cut case that mouse experiments work, because researchers believe that both the phenomena they are studying and the animal models they are using are complex. These assumptions of complexity change the nature of what laboratory work produces. Whereas historical and ethnographic studies traditionally portray the laboratory as a place where scientists control, simplify, and stabilize nature in the service of producing durable facts, the laboratory that emerges from Nelson’s extensive interviews and fieldwork is a place where stable findings are always just out of reach. The ongoing work of managing precarious experimental systems means that researchers learn as much—if not more—about the impact of the environment on behavior as they do about genetics. Model Behavior offers a compelling portrait of life in a twenty-first-century laboratory, where partial, provisional answers to complex scientific questions are increasingly the norm.

Animal Models of Human Behavior

Animal Models of Human Behavior PDF Author: Graham C. L. Davey
Publisher:
ISBN: 9780783773629
Category :
Languages : en
Pages : 383

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Book Description


Animal Models for the Study of Human Disease

Animal Models for the Study of Human Disease PDF Author: P. Michael Conn
Publisher: Academic Press
ISBN: 0124159125
Category : Science
Languages : en
Pages : 1109

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Book Description
Animal Models for the Study of Human Disease identifies important animal models and assesses the advantages and disadvantages of each model for the study of human disease. The first section addresses how to locate resources, animal alternatives, animal ethics and related issues, much needed information for researchers across the biological sciences and biomedicine.The next sections of the work offers models for disease-oriented topics, including cardiac and pulmonary diseases, aging, infectious diseases, obesity, diabetes, neurological diseases, joint diseases, visual disorders, cancer, hypertension, genetic diseases, and diseases of abuse. Organized by disease orientation for ease of searchability Provides information on locating resources, animal alternatives and animal ethics Covers a broad range of animal models used in research for human disease

Animal Models of Human Psychology

Animal Models of Human Psychology PDF Author: Kenneth Joel Shapiro
Publisher: Seattle, [Wash.] ; Toronto : Hogrefe & Huber
ISBN:
Category : Medical
Languages : en
Pages : 352

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Book Description
After surveying current research practices and model development strategies, the author examines animal models of eating disorders from both scientific and ethical points of view. He exposes logical inconsistencies in the study of animals as models for human behavior, and concludes that such research has little to contribute. The foreword is by noted chimpanzee-researcher Jane Goodall. Annotation copyrighted by Book News, Inc., Portland, OR

Animal Models of Human Emotion and Cognition

Animal Models of Human Emotion and Cognition PDF Author: Marc Haug
Publisher: Amer Psychological Assn
ISBN: 9781557985835
Category : Psychology
Languages : en
Pages : 341

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Book Description
This volume intends to demonstrate that theories based on animal studies of brain, behavior, and cognition are indeed providing new insights and directions for research on human function. It is also hoped that this book will promote a dialogue between animal and human researchers that will lead to increased understanding of the complex issues involved in modeling human behavior. /// Part I covers background material against which the subsequent chapters need to be viewed. Part II provides a sampling of the kinds of strategies that animal investigators have used to obtain information that may help alleviate psychiatric and emotional disorders. Part III focuses on animal studies of developmental processes in humans. Part IV focuses on a specific aspect of the perception-cognition continuum: memory processes. Part V discusses aggression. (PsycINFO Database Record (c) 2004 APA, all rights reserved)

Animal Models in Human Psychobiology

Animal Models in Human Psychobiology PDF Author: George Serban
Publisher: Springer Science & Business Media
ISBN: 1468421840
Category : Science
Languages : en
Pages : 297

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Book Description
In March, 1974, an International Symposium was held at the Harmonie Club in New York to discuss a highly pertinent problem in today's research: the "Rele vance of the Animal Psychopathological Model to the Human." This meeting was sponsored by the Kittay Foundation, which brought together an outstanding group of scientists involved in widely different fields of research. This volume, it is hoped, will convey the tone of lively and cordial exchange between inter nationally renowned investigators, including Dr. I. Eibl-Eibesfeldt from Germany, Dr. Robert A. Hinde from England, Dr. Edward F. Domino from Michigan, and Dr. Pierre Pichot from France, Chairman of the Steering Committee. In his welcoming address, Mr. Sol Kittay reminded us that man has achieved remarkable control over his environment but not over himself, and he suggested that we should reexamine our ancestral origins, and search in animal behavior for clues to the understanding of normal and abnormal behavior in man.

Animal Models of Behavior Genetics

Animal Models of Behavior Genetics PDF Author: Jonathan C. Gewirtz
Publisher: Springer
ISBN: 1493937774
Category : Medical
Languages : en
Pages : 395

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Book Description
This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The models highlight genetic causes of core features, or endophenotypes, of developmental, internalizing, and externalizing disorders, as well as dementia. Expert contributors address questions ranging from how suitable species are chosen for study to the costs and benefits of using inbred versus outbred strains, and the effects of housing environment on subject animals. Larger issues addressed include how to evaluate the applicability of animal behavioral models to the human condition and how these models can harness emerging molecular technologies to further our understanding of the genetic basis of mental illness. Included in the coverage: Mating and fighting in Drosophila. Attachment and social bonding. Impulsivity in rodents and humans. Animal models of cognitive decline. Animal models of social cognition. Future directions for animal models in behavioral genetics. A detailed map of where this evolving field is headed, Animal Models of Behavior Genetics shows geneticists, molecular biologists, and cognitive neuroscientists paths beyond established concepts toward a more knowledgeable and collaborative future.

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research

Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research PDF Author: National Research Council
Publisher: National Academies Press
ISBN: 030916785X
Category : Science
Languages : en
Pages : 223

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Book Description
Expanding on the National Research Council's Guide for the Care and Use of Laboratory Animals, this book deals specifically with mammals in neuroscience and behavioral research laboratories. It offers flexible guidelines for the care of these animals, and guidance on adapting these guidelines to various situations without hindering the research process. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research offers a more in-depth treatment of concerns specific to these disciplines than any previous guide on animal care and use. It treats on such important subjects as: The important role that the researcher and veterinarian play in developing animal protocols. Methods for assessing and ensuring an animal's well-being. General animal-care elements as they apply to neuroscience and behavioral research, and common animal welfare challenges this research can pose. The use of professional judgment and careful interpretation of regulations and guidelines to develop performance standards ensuring animal well-being and high-quality research. Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research treats the development and evaluation of animal-use protocols as a decision-making process, not just a decision. To this end, it presents the most current, in-depth information about the best practices for animal care and use, as they pertain to the intricacies of neuroscience and behavioral research.

Methods of Behavior Analysis in Neuroscience

Methods of Behavior Analysis in Neuroscience PDF Author: Jerry J. Buccafusco
Publisher: CRC Press
ISBN: 1420041819
Category : Medical
Languages : en
Pages : 341

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Book Description
Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

The Development of Attachment and Affiliative Systems

The Development of Attachment and Affiliative Systems PDF Author: Robert Emde
Publisher: Springer Science & Business Media
ISBN: 1468440764
Category : Psychology
Languages : en
Pages : 316

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Book Description
The "Development of Attachment and Affiliative Systems" was selected as the topic for a three-day workshop held at Estes Park, Colorado, in May, 1980. The papers which resulted from this effort not only reflect a recent intensity of research in this area, but also highlight a mounting need for ask ing questions across disciplines and for integrating theories. The sponsor of the workshop was the Developmental Psychobiology Research Group (DPRG) of the Department of Psychiatry, University of Colorado Medical School, a group which itself is interdisciplinary and which has met regularly since 1969 to criticize research, ask questions, and discuss findings. In 1974, the Group was awarded an endowment fund by the Grant Foundation after a request for a proposal initiated by Philip Sapir and Douglas Bond. The aims of this fund are to facilitate the research of young investigators, to encourage new research, and to provide seed money for collaborative ventures. Much of what is reported here results from that support. Thus, happily, not only are the contributions timely by virtue of converging on an important topic, but they also commemorate more than five years of Grant Foundation support. Once the topic was chosen, a small number of guests were invited to participate. The papers of Timiras, Sackett, Konner, and Lamb represent dif fering perspectives from neurobiology, primatology, cultural anthropology, and social psychology.