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Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117
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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117
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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: Michitoshi Inoue
Publisher: Springer Science & Business Media
ISBN: 4431683674
Category : Medical
Languages : en
Pages : 330
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Book Description
Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.
Author: Marilyn J. Cipolla
Publisher: Biota Publishing
ISBN: 1615047239
Category : Medical
Languages : en
Pages : 82
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Book Description
This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.
Author: Howard Reisner
Publisher: McGraw Hill Professional
ISBN: 0071821236
Category : Medical
Languages : en
Pages : 622
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Book Description
A unique case-based molecular approach to understanding pathology Pathology: A Modern Case Study is a concise, focused text that emphasizes the molecular and cellular biology essential to understanding the concepts of disease causation. The book includes numerous case studies designed to highlight the role of the pathologist in the team that provides patient care. Pathology: A Modern Case Study examines the role of anatomic, clinical, and molecular pathologists in dedicated chapters and in descriptions of the pathology of specific organ systems. Features Coverage of pathology focuses on modern approaches to common and important diseases Each chapter delivers the most up-to-date advances in pathology Learning aids include chapter summaries and overviews, bolded terms, and a glossary Common clinically relevant disease are highlighted Disease discussion is based on organ compartment and etiology Coverage includes: Disease and the Genome: Genetic, Developmental and Neoplastic Disease Cell Injury, Death and Aging and the Body's Response Environmental Injury Clinical Practice: Anatomic Pathology Clinical Practice: Molecular Pathology Clinical Practice: Molecular Pathology Organ-specific pathology covering all major body systems Molecular pathology Essential for undergraduate medical students and clinicians who wish to expand their knowledge pathology, Pathology: A Modern Case Study delivers valuable coverage that is directly related to a patient’s condition and the clinical practice of pathology.
Author: Donna Bozzone
Publisher: Infobase Holdings, Inc
ISBN: 164693718X
Category : Science
Languages : en
Pages : 96
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Book Description
Composed of the heart, blood vessels, and blood, the circulatory system delivers oxygen and nutrients to every tissue in the body. At the center of this incredibly complex system is the heart, a strong muscle that continuously pumps blood throughout the body. Striving to promote a basic understanding of the fundamental physical and biological principles underlying circulatory functions, The Circulatory System, Third Edition describes the anatomical features of the system and examines how it responds to a broad range of challenges, such as increased activity, the microgravity of space, and hemorrhage. Packed with full-color photographs and illustrations, this absorbing book provides students with sufficient background information through references, websites, and a bibliography.
Author: Conrad J. Storad
Publisher: Lerner Publications
ISBN: 0761374477
Category : Juvenile Nonfiction
Languages : en
Pages : 44
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Book Description
Presents information about the circulatory system, looking at the heart, blood, and blood vessels that compose it, as well as how they work together to keep the body healthy.
Author: Abraham Noordergraaf
Publisher: Elsevier
ISBN: 0323141412
Category : Nature
Languages : en
Pages : 368
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Book Description
Circulatory System Dynamics reviews cardiovascular dynamics from the analytical viewpoint and indicates ways in which the accumulated knowledge can be expanded and applied to further enhance understanding of the normal mammalian circulation, to ascertain the nature of difficulties associated with disease, and to test the effect of treatment. Comprised of 10 chapters, this volume begins with an overview of the circulatory system, including its anatomy and the trigger for myocardial (heart muscle) contraction. The discussion then turns to measurement of blood pressure using invasive and non-invasive techniques; blood flow measurement, with emphasis on cardiac output and measurement in the microcirculation; the system and pulmonary arterial trees; and pulsatile pressure and flow in pulmonary veins. Subsequent chapters explore microcirculation and the anatomy of the microvasculature; the heart and coronary circulation, paying particular attention to the Frank-Starling mechanism and indices of myocardial "contractility"; and control of blood pressure, peripheral resistance, and cerebral flow. The last two chapters deal with circulatory assistance and the closed cardiovascular system. This book will be of interest to students, practitioners, and researchers in fields ranging from physiology and biology to biochemistry and biophysics.
Author: Paul A. Iaizzo
Publisher: Springer
ISBN: 331919464X
Category : Medical
Languages : en
Pages : 806
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Book Description
This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.
Author: Mark E. Oberfield
Publisher: Nova Science Publishers
ISBN: 9781629483085
Category : Cardiovascular system
Languages : en
Pages : 0
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Book Description
The essential components of the human cardiovascular system are the heart, blood, and blood vessels. It includes: pulmonary circulation, a "loop" through the lungs where blood is oxygenated; and systemic circulation, a "loop" through the rest of the body to provide oxygenated blood. In this book, the authors present topical research in the study of the cardiovascular system and its anatomy and physiology, short and long-term effects of exercise and abnormalities. Topics discussed include erythropoietin cell signaling and diseases; cardiovascular morbidities in rheumatoid arthritis and the effects of exercise on cardiac autonomic function; heart rate variability (HRV) assessment of physical training effects on autonomic cardiac control; endoplasmic reticulum stress in cardiovascular disease; and renal sympathetic denervation for resistant hypertension.
Author: Gerhard A. Holzapfel
Publisher: Springer
ISBN: 370912736X
Category : Technology & Engineering
Languages : en
Pages : 348
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Book Description
The book is written by leading experts in the field presenting an up-to-date view of the subject matter in a didactically sound manner. It presents a review of the current knowledge of the behaviour of soft tissues in the cardiovascular system under mechanical loads, and the importance of constitutive laws in understanding the underlying mechanics is highlighted. Cells are also described together with arteries, tendons and ligaments, heart, and other biological tissues of current research interest in biomechanics. This includes experimental, continuum mechanical and computational perspectives, with the emphasis on nonlinear behaviour, and the simulation of mechanical procedures such as balloon angioplasty.
