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Author: Giacomo Zaccone
Publisher: CRC Press
ISBN: 1439843597
Category : Science
Languages : en
Pages : 465
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Book Description
This book provides a comprehensive and up-to-date account of the information available on the morphological, physiological and evolutionary aspects of specialized cells distributed within the epithelia of the airways in the vertebrates. A lot of work has been done on the cell and molecular biology of these cells which are regarded as as oxygen receptor neuroepithelial cells. These chemoreceptors which were conserved throughout evolution have neuroendocrine functions carrying their signals to the central nervous system. The chemoreceptor cells are sensors which detect the signal changes in the external and internal environments, and play a key role in the survival of various species. Studies addressed to the chemoreceptor cell systems in the airways are of great importance for investigating their response to changes in the oxygen and carbon dioxide concentrations in the environment since the future of the planet earth is being threatened by global warming and climate change. Praise for the book: ...This volume would be of special interest to researchers who are curious about the evolution of vertebrate respiratory control in general and the regulation of ventilation in nonmammalian vertebrates in particular. -Wayne L. Silver, Wake Forest University, in The Quarterly Review of Biology, Volume 85, Number 2
Author: Giacomo Zaccone
Publisher: CRC Press
ISBN: 1439843597
Category : Science
Languages : en
Pages : 465
Get Book Here
Book Description
This book provides a comprehensive and up-to-date account of the information available on the morphological, physiological and evolutionary aspects of specialized cells distributed within the epithelia of the airways in the vertebrates. A lot of work has been done on the cell and molecular biology of these cells which are regarded as as oxygen receptor neuroepithelial cells. These chemoreceptors which were conserved throughout evolution have neuroendocrine functions carrying their signals to the central nervous system. The chemoreceptor cells are sensors which detect the signal changes in the external and internal environments, and play a key role in the survival of various species. Studies addressed to the chemoreceptor cell systems in the airways are of great importance for investigating their response to changes in the oxygen and carbon dioxide concentrations in the environment since the future of the planet earth is being threatened by global warming and climate change. Praise for the book: ...This volume would be of special interest to researchers who are curious about the evolution of vertebrate respiratory control in general and the regulation of ventilation in nonmammalian vertebrates in particular. -Wayne L. Silver, Wake Forest University, in The Quarterly Review of Biology, Volume 85, Number 2
Author: Giacomo Zaccone
Publisher:
ISBN: 9780429541407
Category : MEDICAL
Languages : en
Pages :
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Book Description
The book provides a comprehensive and up-to-date account of the information available on the morphological, physiological and evolutionary aspects of specialized cells distributed within the epithelia of the airways in the vertebrates. A lot of work has been done on the cell and molecular biology of these cells which are regarded as as oxygen recep
Author: Göran E. Nilsson
Publisher: Cambridge University Press
ISBN: 1139485350
Category : Science
Languages : en
Pages : 351
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Book Description
How do vertebrates get the oxygen they need, or even manage without it for shorter or longer periods of time? How do they sense oxygen, how do they take it up from water or air, and how do they transport it to their tissues? Respiratory system adaptations allow numerous vertebrates to thrive in extreme environments where oxygen availability is limited or where there is no oxygen at all. Written for students and researchers in comparative physiology, this authoritative summary of vertebrate respiratory physiology begins by exploring the fundamentals of oxygen sensing, uptake and transport in a textbook style. Subsequently, the reader is shown important examples of extreme respiratory performance, like diving and high altitude survival in mammals and birds, air breathing in fish, and those few vertebrates that can survive without any oxygen at all for several months, showing how evolution has solved the problem of life without oxygen.
Author: Mogens L. Glass
Publisher: Springer Science & Business Media
ISBN: 3540939857
Category : Science
Languages : en
Pages : 543
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Book Description
Hopefully, this book will be taken off of the shelf frequently to be studied carefully over many years. More than 40 researchers were involved in this project, which examines respiration, circulation, and metabolism from ?sh to the land vertebrates, including human beings. A breathable and stable atmosphere ?rst appeared about 500 million years ago. Oxygen levels are not stable in aquatic environments and exclusively water-breathing ?sh must still cope with the ever-changing levels of O 2 and with large temperature changes. This is re?ected in their sophisticated count- current systems, with high O extraction and internal and external O receptors. 2 2 The conquest for the terrestrial environment took place in the late Devonian period (355–359 million years ago), and recent discoveries portray the gradual transitional evolution of land vertebrates. The oxygen-rich and relatively stable atmospheric conditionsimpliedthatoxygen-sensingmechanismswererelativelysimpleandl- gain compared with acid–base regulation. Recently, physiology has expanded into related ?elds such as biochemistry, molecular biology, morphology and anatomy. In the light of the work in these ?elds, the introduction of DNA-based cladograms, which can be used to evaluate the likelihood of land vertebrates and lung?sh as a sister group, could explain why their cardio-respiratory control systems are similar. The diffusing capacity of a duck lung is 40 times higher than that of a toad or lung?sh. Certainly, some animals have evolved to rich high-performance levels.
Author: Steven F. Perry
Publisher:
ISBN: 0199238464
Category : Medical
Languages : en
Pages : 249
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Book Description
This book discusses aerobic metabolism at all levels, from the gas exchange organs to mitochondria including aspects of morphology and physiology as well as the control of breathing in the central nervous system.
Author:
Publisher: Academic Press
ISBN: 0080923232
Category : Science
Languages : en
Pages : 2275
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Book Description
Fish form an extremely diverse group of vertebrates. At a conservative estimate at least 40% of the world's vertebrates are fish. On the one hand they are united by their adaptations to an aquatic environment and on the other they show a variety of adaptations to differing environmental conditions - often to extremes of temperature, salinity, oxygen level and water chemistry. They exhibit an array of behavioural and reproductive systems. Interesting in their own right, this suite of adaptive physiologies provides many model systems for both comparative vertebrate and human physiologists. This four volume encyclopedia covers the diversity of fish physiology in over 300 articles and provides entry level information for students and summary overviews for researchers alike. Broadly organised into four themes, articles cover Functional, Thematic, and Phylogenetic Physiology, and Fish Genomics. Functional articles address the traditional aspects of fish physiology that are common to all areas of vertebrate physiology including: Reproduction, Respiration, Neural (Sensory, Central, Effector), Endocrinology, Renal, Cardiovascular, Acid-base Balance, Osmoregulation, Ionoregulation, Digestion, Metabolism, Locomotion, and so on. Thematic Physiology articles are carefully selected and fewer in number. They provide a level of integration that goes beyond the coverage in the Functional Physiology topics and include discussions of Toxicology, Air-breathing, Migrations, Temperature, Endothermy, etc. Phylogenetic Physiology articles bring together information that bridges the physiology of certain groupings of fishes where the knowledge base has a sufficient depth and breadth and include articles on Ancient Fishes, Tunas, Sharks, etc. Genomics articles describe the underlying genetic component of fish physiology and high light their suitability and use as model organisms for the study of disease, stress and physiological adaptations and reactions to external conditions. Winner of a 2011 PROSE Award Honorable Mention for Multivolume Science Reference from the Association of American Publishers The definitive encyclopedia for the field of fish physiology Three volumes which comprehensively cover the entire field in over 300 entries written by experts Detailed coverage of basic functional physiology of fishes, physiological themes in fish biology and comparative physiology amongst taxonomic Groups Describes the genomic bases of fish physiology and biology and the use of fish as model organisms in human physiological research Includes a glossary of terms
Author: Ernest Cutz
Publisher: FriesenPress
ISBN: 1525561340
Category : Biography & Autobiography
Languages : en
Pages : 217
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Book Description
Within the world of medicine, the work the pathologist does is integral to positive patient outcomes, but it is rare for the pathologist to actually have any interaction with their patients. Thus, their work can often go unrecognized and uncelebrated. The Unsung Heroes of Paediatric Medicine paints a broad portrait of the myriad facets that go into the making of a superb department of paediatric pathology. Not only is it the science, but it is also the people that helped to make a department such as this grow and flourish, becoming one of the best, if not the best, in North America. Within these pages, Dr. Cutz walks the reader through a century of pediatric pathology at Sick Kids Hospital in Toronto, Ontario. Building on both personal experience and archival material, Dr. Cutz’s memoir touches on the history of pathology and the evolution of pediatric pathology, then moves into a detailed overview of both the leadership and staff of the Department of Pathology at Sick Kids Hospital. In addition, readers can follow Dr. Cutz’s personal journey from his research fellowship to his beginnings as a staff pathologist, ending with his research advances and breakthroughs all made whilst a pathologist at Sick kids. Unsung Heroes also touches on controversies, tragedies, and challenging events from the hospital's history, including digoxin, the Olivieri affair, the rise and fall of Charles Smith, and the Mother Risk controversy, among others.
Author: Jeffrey B. Graham
Publisher: Elsevier
ISBN: 0080525490
Category : Science
Languages : en
Pages : 313
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Book Description
Air Breathing Fishes: Evolution, Diversity, and Adaptation is unique in its coverage of the evolution of air-breathing, incongruously because it focuses exclusively on fish. This important and fascinating book, containing nine chapters that present the life history, ecology, and physiology of many air-breathing fishes, provides an exceptional overview of air-breathing biology.Each chapter provides a historical background, details the present status of knowledge in the field, and defines the questions needing attention in future research. Thoroughly referenced, containing more than 1,000 citations, and well documented with figures and tables, Air-Breathing Fishes is comprehensive in its coverage and will certainly have wide appeal. Researchers in vertebrate biology, paleontology, ichthyology, vertebrate evolution, natural history, comparative physiology, anatomy and many other fields will find something new and intriguing in Air-Breathing Fishes. - Offers a complete overview of an important and immensely interesting area of research - Provides a perspective of air-breathing fish that spans 300 million years of vertebrate evolution - Contains numerous illustrations as well as comprehensive charts - Provides a synoptic treatment of all the known air-breathing species with important data on their morphological and physiological adaptations
Author: Donald W. Pfaff
Publisher: Springer
ISBN: 9781493934737
Category : Medical
Languages : en
Pages : 0
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Book Description
Edited and authored by a wealth of international experts in neuroscience and related disciplines, this key new resource aims to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a strategic battleground in the future of medicine, as the prevalence of mental disorders is becoming better understood each year. Hundreds of millions of people worldwide are affected by mental, behavioral, neurological and substance use disorders. The World Health Organization estimated in 2002 that 154 million people globally suffer from depression and 25 million people from schizophrenia; 91 million people are affected by alcohol use disorders and 15 million by drug use disorders. A more recent WHO report shows that 50 million people suffer from epilepsy and 24 million from Alzheimer’s and other dementias. Because neuroscience takes the etiology of disease—the complex interplay between biological, psychological, and sociocultural factors—as its object of inquiry, it is increasingly valuable in understanding an array of medical conditions. A recent report by the United States’ Surgeon General cites several such diseases: schizophrenia, bipolar disorder, early-onset depression, autism, attention deficit/ hyperactivity disorder, anorexia nervosa, and panic disorder, among many others. Not only is this volume a boon to those wishing to understand the future of neuroscience, it also aims to encourage the initiation of neuroscience programs in developing countries, featuring as it does an appendix full of advice on how to develop such programs. With broad coverage of both basic science and clinical issues, comprising around 150 chapters from a diversity of international authors and including complementary video components, Neuroscience in the 21st Century in its second edition serves as a comprehensive resource to students and researchers alike.
Author: Inge Brouns
Publisher: Springer Nature
ISBN: 3030658171
Category : Medical
Languages : en
Pages : 112
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Book Description
This monograph sheds new light on pulmonary sensory receptors. Diving into the pulmonary microenvironment, the book focuses on the role of pulmonary neuroepithelial bodies (NEBs) as potential receptors and effectors, able to store and release neurotransmitters. It explores NEBs as potential stem cell niche and highlights the multidisciplinary approach taken to identify and study NEBs, including functional morphological investigation, live cell imaging, genetic models, and laser microdissection combined with gene expression analysis. Complexly organized NEBs are an integral part of the intrapulmonary airway epithelium of all air-breathing vertebrates. For decades a quest has been going on to unravel the functional significance of these intriguing structures that appear to be modified in the course of many pulmonary diseases. The NEB microenvironment (ME) is composed of organoid clusters of pulmonary neuroendocrine cells (PNECs) that are able to store and release neurotransmitters and are closely contacted by extensive nerve terminals, emphasizing a potential receptor/effector role and probable signalling to the central nervous system. PNECs are largely shielded from the airway lumen by a special type of Clara cells, the Clara-like cells, with potential stem cell characteristics. So far, functional studies of the pulmonary NEB ME revealed that PNECs can be activated by various mechanical and chemical stimuli, resulting in a calcium-mediated release of neurotransmitters. In the past decades, a number of publications have exposed NEBs as potential hypoxia sensors. Recent experimental evidence unveiled that the NEB ME is a quiescent stem cell niche in healthy postnatal lungs, and silencing may involve bone morphogenetic protein signalling mediated by vagal afferents. Only an integrated approach that takes all current information into account will be able to explain the full role of the pulmonary NEB ME in health and disease. This highly informative and carefully presented book, provides insights for researchers, PhD students with an interest in (bio)medical and veterinary science, especially in the field of the autonomic innervation of the lung, chemo-and mechanoreceptors
