Advances in Diagnostics and Treatment of Functional Neurological Disorders: Neurogenomics, Neuromodulation and Machine-Learning

Advances in Diagnostics and Treatment of Functional Neurological Disorders: Neurogenomics, Neuromodulation and Machine-Learning PDF Author: Guohui Lu
Publisher: Frontiers Media SA
ISBN: 2832503705
Category : Science
Languages : en
Pages : 359

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Book Description

Advances in Diagnostics and Treatment of Functional Neurological Disorders: Neurogenomics, Neuromodulation and Machine-Learning

Advances in Diagnostics and Treatment of Functional Neurological Disorders: Neurogenomics, Neuromodulation and Machine-Learning PDF Author: Guohui Lu
Publisher: Frontiers Media SA
ISBN: 2832503705
Category : Science
Languages : en
Pages : 359

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Book Description


Augmenting Neurological Disorder Prediction and Rehabilitation Using Artificial Intelligence

Augmenting Neurological Disorder Prediction and Rehabilitation Using Artificial Intelligence PDF Author: Anitha S. Pillai
Publisher: Academic Press
ISBN: 0323886264
Category : Science
Languages : en
Pages : 356

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Book Description
Augmenting Neurological Disorder Prediction and Rehabilitation Using Artificial Intelligence focuses on how the neurosciences can benefit from advances in AI, especially in areas such as medical image analysis for the improved diagnosis of Alzheimer’s disease, early detection of acute neurologic events, prediction of stroke, medical image segmentation for quantitative evaluation of neuroanatomy and vasculature, diagnosis of Alzheimer’s Disease, autism spectrum disorder, and other key neurological disorders. Chapters also focus on how AI can help in predicting stroke recovery, and the use of Machine Learning and AI in personalizing stroke rehabilitation therapy. Other sections delve into Epilepsy and the use of Machine Learning techniques to detect epileptogenic lesions on MRIs and how to understand neural networks. Provides readers with an understanding on the key applications of artificial intelligence and machine learning in the diagnosis and treatment of the most important neurological disorders Integrates recent advancements of artificial intelligence and machine learning to the evaluation of large amounts of clinical data for the early detection of disorders such as Alzheimer’s Disease, autism spectrum disorder, Multiple Sclerosis, headache disorder, Epilepsy, and stroke Provides readers with illustrative examples of how artificial intelligence can be applied to outcome prediction, neurorehabilitation and clinical exams, including a wide range of case studies in predicting and classifying neurological disorders

Cumulated Index Medicus

Cumulated Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1860

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An Essay on the Shaking Palsy

An Essay on the Shaking Palsy PDF Author: James Parkinson
Publisher:
ISBN:
Category : Parkinson's disease
Languages : en
Pages : 86

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Cerebellar Disorders

Cerebellar Disorders PDF Author: Mario Ubaldo Manto
Publisher: Cambridge University Press
ISBN: 1139487264
Category : Medical
Languages : en
Pages : 313

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Book Description
During the last three decades, many laboratories worldwide have dedicated their research activities to understanding the roles of the cerebellum in motor control, cognitive processes and the biology of mental processes, behavioral symptoms and emotion. These advances have been associated with discoveries of new clinical disorders, in particular in the field of genetic ataxias, and the growing number of diseases presents a source of difficulty for clinicians during daily practice. This practical guide summarizes and evaluates current knowledge in the field of cerebellar disorders. Encompassing details of both common and uncommon cerebellar ataxias, including vascular, immune, neoplastic, infectious, traumatic, toxic and inherited disorders, this book will assist clinicians in the diagnosis and management of the full spectrum of cerebellar ataxias encountered in daily practice. Essential reading for clinicians, including general practitioners, neurologists, pediatricians, radiologists, psychiatrists and neuropsychologists, this will also prove a valuable tool for students, trainees and researchers.

Encyclopedia of the Neurological Sciences

Encyclopedia of the Neurological Sciences PDF Author:
Publisher: Academic Press
ISBN: 0123851580
Category : Medical
Languages : en
Pages : 4744

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Book Description
The Encyclopedia of the Neurological Sciences, Second Edition, Four Volume Set develops from the first edition, covering all areas of neurological sciences through over 1000 entries focused on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. The contributing authors represent all aspects of neurology from many viewpoints and disciplines to provide a complete overview of the field. Entries are designed to be understandable without detailed background knowledge in the subject matter, and cross-referencing and suggested further reading lead the reader from a basic knowledge of the subject to more advanced understanding. The easy-to-use 'encyclopedic-dictionary' format of the Encyclopedia of the Neurological Sciences, Second Edition features alphabetic entries, extensive cross-referencing, and a thorough index for quick reference. The wealth of information provided by these four volumes makes this reference work a trusted source of valuable information for a wide range of researchers, from undergraduate students to academic researchers. Provides comprehensive coverage of the field of neurological science in over 1,000 entries in 4 volumes "Encyclopedic-dictionary" format provides for concise, readable entries and easy searching Presents complete, up-to-date information on 32 separate areas of neurology Entries are supplemented with extensive cross-referencing, useful references to primary research articles, and an extensive index

Invasive Studies of the Human Epileptic Brain

Invasive Studies of the Human Epileptic Brain PDF Author: Samden D. Lhatoo
Publisher: Oxford University Press, USA
ISBN: 0198714661
Category : Medical
Languages : en
Pages : 577

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Book Description
Invasive Studies of the Human Epileptic Brain is the definitive reference text on the use of invasive electroencephalographic (EEG) diagnostic studies in human epilepsy.

Connectomic Deep Brain Stimulation

Connectomic Deep Brain Stimulation PDF Author: Andreas Horn
Publisher: Academic Press
ISBN: 0128218622
Category : Medical
Languages : en
Pages : 602

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Book Description
Connectomic Deep Brain Stimulation (DBS) covers this highly efficacious treatment option for movement disorders such as Parkinson’s Disease, Essential Tremor and Dystonia. The book examines its impact on distributed brain networks that span across the human brain in parallel with modern-day neuroimaging concepts and the connectomics of the brain. It asks several questions, including which cortical areas should DBS electrodes be connected in order to generate the highest possible clinical improvement? Which connections should be avoided? Could these connectomic insights be used to better understand the mechanism of action of DBS? How can they be transferred to individual patients, and more. This book is suitable for neuroscientists, neurologists and functional surgeons studying DBS. It provides practical advice on processing strategies and theoretical background, highlighting and reviewing the current state-of-the-art in connectomic surgery. Written to provide a "hands-on" approach for neuroscience graduate students, as well as medical personnel from the fields of neurology and neurosurgery Includes preprocessing strategies (such as co-registration, normalization, lead localization, VTA estimation and fiber-tracking approaches) Presents references (key articles, books and protocols) for additional detailed study Provides data analysis boxes in each chapter to help with data interpretation

RNA Metabolism in Neurodegenerative Diseases

RNA Metabolism in Neurodegenerative Diseases PDF Author: Rita Sattler
Publisher: Springer
ISBN: 331989689X
Category : Medical
Languages : en
Pages : 321

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Book Description
It has become evident over the last years that abnormalities in RNA processing play a fundamental part in the pathogenesis of neurodegenerative diseases. Cellular viability depends on proper regulation of RNA metabolism and subsequent protein synthesis, which requires the interplay of many processes including transcription, pre--‐mRNA splicing, mRNA editing as well as mRNA stability, transport and translation. Dysfunction in any of these processes, often caused by mutations in the coding and non--‐ coding RNAs, can be very destructive to the cellular environment and consequently impair neural viability. The result of this RNA toxicity can lead to a toxic gain of function or a loss of function, depending on the nature of the mutation. For example, in repeat expansion disorders, such as the newly discovered hexanucleotide repeat expansion in theC9orf72 gene found in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), a toxic gain of function leads to the formation of RNA foci and the sequestration of RNA binding proteins (RBPs). This in return leads to a loss of function of those RBPs, which is hypothesized to play a significant part in the disease progression of ALS and FTD. Other toxicities arising from repeat expansions are the formation of RNA foci, bi--‐directional transcription and production of repeat associated non--‐ATG (RAN) translation products. This book will touch upon most of these disease mechanisms triggered by aberrant RNA metabolism and will therefore provide a broad perspective of the role of RNA processing and its dysfunction in a variety of neurodegenerative disorders, including ALS, FTD, Alzheimer’s disease, Huntington’s disease, spinal muscular atrophy, myotonic dystrophy and ataxias. The proposed authors are leading scientists in the field and are expected to not only discuss their own work, but to be inclusive of historic as well as late breaking discoveries. The compiled chapters will therefore provide a unique collection of novel studies and hypotheses aimed to describe the consequences of altered RNA processing events and its newest molecular players and pathways.

Computational Psychiatry

Computational Psychiatry PDF Author: A. David Redish
Publisher: MIT Press
ISBN: 0262035421
Category : Science
Languages : en
Pages : 425

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Book Description
Psychiatrists and neuroscientists discuss the potential of computational approaches to address problems in psychiatry including diagnosis, treatment, and integration with neurobiology. Modern psychiatry is at a crossroads, as it attempts to balance neurological analysis with psychological assessment. Computational neuroscience offers a new lens through which to view such thorny issues as diagnosis, treatment, and integration with neurobiology. In this volume, psychiatrists and theoretical and computational neuroscientists consider the potential of computational approaches to psychiatric issues. This unique collaboration yields surprising results, innovative synergies, and novel open questions. The contributors consider mechanisms of psychiatric disorders, the use of computation and imaging to model psychiatric disorders, ways that computation can inform psychiatric nosology, and specific applications of the computational approach. Contributors Susanne E. Ahmari, Huda Akil, Deanna M. Barch, Matthew Botvinick, Michael Breakspear, Cameron S. Carter, Matthew V. Chafee, Sophie Denève, Daniel Durstewitz, Michael B. First, Shelly B. Flagel, Michael J. Frank, Karl J. Friston, Joshua A. Gordon, Katia M. Harlé, Crane Huang, Quentin J. M. Huys, Peter W. Kalivas, John H. Krystal, Zeb Kurth-Nelson, Angus W. MacDonald III, Tiago V. Maia, Robert C. Malenka, Sanjay J. Mathew, Christoph Mathys, P. Read Montague, Rosalyn Moran, Theoden I. Netoff, Yael Niv, John P. O'Doherty, Wolfgang M. Pauli, Martin P. Paulus, Frederike Petzschner, Daniel S. Pine, A. David Redish, Kerry Ressler, Katharina Schmack, Jordan W. Smoller, Klaas Enno Stephan, Anita Thapar, Heike Tost, Nelson Totah, Jennifer L. Zick