Adrenal in Toxicology PDF Download
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Author: Philip W. Harvey
Publisher: CRC Press
ISBN: 0748403302
Category : Medical
Languages : en
Pages : 331
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Book Description
The adrenal gland is vitally important to health and secretes hormones that control many bodily processes ranging from normal metabolism to the response to stressful circumstances. The corticosteroid hormones are the basis for anti-inflammatory medicines and are very widely prescribed. Changes in the function of the adrenal gland, either naturally through stress or disease, or through the action of drugs and chemicals, can have a major impact on the body.; This text focuses on adrenal toxicity, examining how drugs and chemicals can directly and indirectly affect this gland. Coverage includes: classification of the types of adrenal and endocrine toxicity; the mechanistic and molecular basis of toxicity; reasons why the adrenal is the most common target organ in the endocrine system; drug toxicity specific to patients with adrenal disorders; drug- corticosteroid interactions; adverse drug reactions; and how the adrenal gland is vital in tolerance to toxic insult.
Author: Philip W. Harvey
Publisher: CRC Press
ISBN: 0748403302
Category : Medical
Languages : en
Pages : 331
Get Book Here
Book Description
The adrenal gland is vitally important to health and secretes hormones that control many bodily processes ranging from normal metabolism to the response to stressful circumstances. The corticosteroid hormones are the basis for anti-inflammatory medicines and are very widely prescribed. Changes in the function of the adrenal gland, either naturally through stress or disease, or through the action of drugs and chemicals, can have a major impact on the body.; This text focuses on adrenal toxicity, examining how drugs and chemicals can directly and indirectly affect this gland. Coverage includes: classification of the types of adrenal and endocrine toxicity; the mechanistic and molecular basis of toxicity; reasons why the adrenal is the most common target organ in the endocrine system; drug toxicity specific to patients with adrenal disorders; drug- corticosteroid interactions; adverse drug reactions; and how the adrenal gland is vital in tolerance to toxic insult.
Author: Philip W. Harvey
Publisher:
ISBN: 9780429148781
Category : Adrenal glands
Languages : en
Pages : 310
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Book Description
Author: Harvey
Publisher:
ISBN: 9780333631690
Category :
Languages : en
Pages :
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Book Description
Author: C. K. Atterwill
Publisher: Cambridge University Press
ISBN: 9780521402255
Category : Medical
Languages : en
Pages : 504
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Book Description
This is the first book to deal comprehensively with endocrine toxicology. It covers the whole spectrum of known toxicant effects on the endocrine system ranging from small disturbances in hormonal secretion to full endocrine neoplasia. In each chapter, internationally recognised authorities have addressed basic endocrine physiology, current techniques for studying endocrine toxicity in vivo and in vitro, known xenobiotic-induced toxicity phenomena and the latest scientific advances in understanding the underlying molecular and cellular events. Consideration is given to important issues such as dietary factors which influence endocrine toxicity, species differences in sensitivity to toxicants, and the toxicity of hormones and drugs. The volume provides a sound basis for understanding the scientific aspects of this complex and important area of toxicology and will be a useful source of information for all those working in this field.
Author: Pharmaceutical Manufacturers Association. Drug Safety Subsection
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Robert M. Diener
Publisher:
ISBN:
Category :
Languages : en
Pages : 109
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Book Description
Author: John A. Thomas
Publisher: CRC Press
ISBN: 9781560326137
Category : Medical
Languages : en
Pages : 339
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Book Description
This text presents a range of topics from the molecular events surrounding hormone actions to epidemiologic studies of the effects of environmental and occupational chemicals on reproductive organs. The endocrine systems covered include the adrenal cortex, thyroid and parathyroid, gonads, and the endocrine pancreas. Of particular importance are the chapters covering the general characteristics of the estrogen receptors and the androgen receptors. The book also describes some of the underlying toxic mechanisms involving pancreatic B cells and metal-induced changes in male sex accessory glands.
Author: Fergus M. Clydesdale
Publisher: CRC Press
ISBN: 9780849385803
Category : Technology & Engineering
Languages : en
Pages : 36
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Book Description
In the U.S., before any additive is added to a food product the manufacturer must submit it to the FDA for approval and prove that its use has a reasonable certainty of not causing harm. The Priority-Based Assessment of Food Additives (PAFA) Database, compiled and maintained by the U.S. FDA/CFSAN (Center for Food Safety and Applied Nutrition), is a team resource for evaluating the status of all food additives. Food Additives: Toxicology, Regulation, and Properties contains a wealth of facts regarding the chemical and toxicological effects of direct food additives. It consists of identifying/administrative information for nearly 2,000 compounds that are, could be, or have been added to the U.S. food supply. Limited information is also provided for an additional 1,000 compounds. Part 1, Administrative and Chemical Information, includes data such as the CAS registry number, name of the compound, other identifying numbers, exposure to the population, and much more. The toxicological data fields are divided into three main sections: Genetic Toxicity and Cytotoxicity Information, Acute Toxicology Information, and Oral Toxicology Information. These sections contain data from toxicological studies.
Author:
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1130
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Book Description
Author: Gary D. Hammer
Publisher: Springer Science & Business Media
ISBN: 0387772367
Category : Medical
Languages : en
Pages : 533
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Book Description
We anticipate the book to be a definitive text on the subject that explores all aspects of the study of adrenal cancer and the treatment of patients with the disease. Chapters will cover epidemiology, pathogenesis, genetics, cancer stem cells, historic and emerging therapies, mouse models of adrenal cancer, new developments in tumor profiling, worldwide collaborative groups and tumor registries together with resources for the practitioner and community of adrenal cancer scientists. We do not wish this book to compete with the other larger books in the Endocrine and Endocrine Surgery literature. In addition, it is not expected to cover benign adrenal diseases that have been covered in detail in other venues. We envision this book to be a very specialized and exhaustive text on basic, translational and clinical aspects of adrenal cancer.
