Proceedings of the International Symposia of the Princess Takamatsu Cancer Research Fund, Volume 13 ADP-Ribosylation, DNA Repair and Cancer PDF Download
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Author: Sugimura
Publisher: CRC Press
ISBN: 1000109739
Category : Science
Languages : en
Pages : 355
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Book Description
Proceedings of the 13th International Symposium of The Princess Takamatsu Cancer Research Fund, held in Tokyo The proceedings deal with the potential relevance of ADP-ribosylation reactions in the genesis, prevention and treatment of cancer. These reactions were independently discovered in the laboratories of Paul Mandel, Osamu Hayaishi and Takashi Sugimura, all whom contribute to ADP-Ribosylation, DNA Repair and Cancer. Apart from these renowned scientists, many other outstanding researchers from the international research community have contributed chapters discussing their most recent research results.
Author: Sugimura
Publisher: CRC Press
ISBN: 1000109739
Category : Science
Languages : en
Pages : 355
Get Book Here
Book Description
Proceedings of the 13th International Symposium of The Princess Takamatsu Cancer Research Fund, held in Tokyo The proceedings deal with the potential relevance of ADP-ribosylation reactions in the genesis, prevention and treatment of cancer. These reactions were independently discovered in the laboratories of Paul Mandel, Osamu Hayaishi and Takashi Sugimura, all whom contribute to ADP-Ribosylation, DNA Repair and Cancer. Apart from these renowned scientists, many other outstanding researchers from the international research community have contributed chapters discussing their most recent research results.
Author: Alexander Bürkle
Publisher: Springer Science & Business Media
ISBN: 0387360050
Category : Medical
Languages : en
Pages : 260
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Book Description
This is the most comprehensive, up-to-date reference on this post-translational modification of proteins, which is intimately linked with DNA repair, maintenance of genomic stability, transcriptional regulation, cell death and a variety of other cellular phenomena as well as with a variety of pathophysiological conditions, including ischemia-reperfusion damage, Parkinson’s disease, Type I diabetes mellitus, hemorrhagic and septic shock and other inflammatory conditions. Richly illustrated, it offers 19 chapters written by international experts.
Author: R. Alvarez-Gonzalez
Publisher: Springer Science & Business Media
ISBN: 1441987401
Category : Science
Languages : en
Pages : 156
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Book Description
This special issue of Molecular and Cellular Biochemistry contains twenty-two selected research papers and reviews from a total of one hundred and ten presentations given at the 12th International Symposium on ADP-ribosylation Reactions: From Bacterial Pathogenesis to Cancer, held in Cancun, Mexico, May 10-14, 1997. The Symposium was hosted by the Sociedad Mexicana de Bioquimica and was sponsored by the University of North Texas Health Science Center, Fort Worth, TX, USA. This volume provides a state-of-the-art source of information for basic scientists and clinicians who are interested in the molecular, biochemical, and cellular aspects of protein-(ADP-ribose) transfer reactions in human health and disease.
Author: Masanao Miwa
Publisher:
ISBN:
Category :
Languages : en
Pages : 338
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Book Description
Author: Srinivasan Madhusudan
Publisher: CRC Press
ISBN: 1466577444
Category : Medical
Languages : en
Pages : 714
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Book Description
DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topi
Author: Guy G. Poirier
Publisher: Springer Science & Business Media
ISBN: 1441987185
Category : Science
Languages : en
Pages : 438
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Book Description
This monograph is dedicated to one of the discoverers of poly(ADP ribose), Professor Paul Mandel, from the Centre de Neurochimie in Strasbourg. We would like to congratulate him for his distinguished contributions to the field of poly(ADP-ribosyl)ation and express our gratitude for his support in the last years and particularly for his encouragement for the organization of this meeting. Poly(ADP-ribose) was discovered more than 25 years ago. Since then, excellent progress has been made on the study of the mechanisms of poly(ADP ribose) reaction. The last five years have been particularly exciting since the development of various molecular biology techniques has revealed the complex nature of this multifunctional enzyme. Looking at the contributions presented at this meeting, it becomes obvious that more work at the molecular level is needed. Most likely, these experiments will shed some light on the functions of poly(ADP-ribose), but further ~iophysical studies will still be required to fully understand this complex enzymatic system.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: Felix R. Althaus
Publisher: Springer Science & Business Media
ISBN: 3642705898
Category : Science
Languages : en
Pages : 594
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Book Description
This book provides an update on recent advances in the field of ADP ribosylation reactions. The individual chapters represent the synopses of contributions which were presented at the Seventh International Symposium on ADP-Ribosylation Reactions, held in Vitznau, Switzer land, from September 23 to 27, 1984. This volume covers new devel opments in the field since the last meeting was held on this topic in 1982, in Tokyo. Therefore, the present text is not meant to form a comprehensive account of a specialized research area, but encompasses a collection of state-of-the-art reports from the vast majority of laboratories currently involved in ADP-ribosylation work. For the sake of rapid publication, the editorial policy was to ensure easy accessibility of information contained in individual articles rather than to provide elaborate cross references or reference to work published prior to 1982. However, a detailed subject index will help the reader find complementary information. The enzymes of ADP-ribose metabolism have not yet acquired universally acceptable trivial names and the Enzyme Commission has not yet defmitely decided on formal appellations. Consequently, a variety of names for the nuclear enzyme appear in this book, including nuc1ear(ADP-ribosyl)transferase, poly(ADP-ribose) polymerase, or synthetase or synthase. Hopefully, a common convention will soon be established. The Seventh International Symposium on ADP-Ribosylation Reac tions was only possible because of the generous support which we have been given by our sponsors, listed below.
Author: Sugimura
Publisher: CRC Press
ISBN: 9789067640039
Category : Science
Languages : en
Pages : 338
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Book Description
Proceedings of the 13th International Symposium of The Princess Takamatsu Cancer Research Fund, held in Tokyo The proceedings deal with the potential relevance of ADP-ribosylation reactions in the genesis, prevention and treatment of cancer. These reactions were independently discovered in the laboratories of Paul Mandel, Osamu Hayaishi and Takashi Sugimura, all whom contribute to ADP-Ribosylation, DNA Repair and Cancer. Apart from these renowned scientists, many other outstanding researchers from the international research community have contributed chapters discussing their most recent research results.
Author: Timothy A. Yap
Publisher: Springer Nature
ISBN: 3031300653
Category : Medical
Languages : en
Pages : 333
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Book Description
This book discusses the latest developments in Poly (ADP-ribose) polymerase (PARP) inhibitor drug development. It focuses on the translational and clinical development of the latest drugs, as well as the evidence for regulatory approval of PARP inhibitors in multiple different molecular subtypes and tumor indications. The most-up-to-date information on basic scientific research on DNA repair pathways and the DNA Damage Response (DDR) is also covered. Every chapter contains insight into the preclinical, translational along with clinical aspects of a specific DDR inhibitor with key and expert opinion points reinforcing the most important concepts detailed to enable the reader to develop a deep understanding of the topic. Targeting the DNA Damage Response for Cancer Therapy comprehensively reviews the application of PARP and other DDR inhibitors across oncology disciplines. Therefore, it is a valuable resource for all medical professionals and researchers who use or who are researching the use of these inhibitors on a day-to-day basis.
