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Author: J. Standefer
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1
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Book Description
The objective of the two-volume series Disposition of Toxic Drugs and Chemicals in Man is to provide reference information on the pharmacokinetics and metabolism of drugs commonly encountered in forensic and clinical practice as well as to provide useful interpretative and diagnostic information for the toxicologist. Volume I provides this information on commonly encountered centrally acting drugs while Volume II provides information on peripherally acting drugs and toxins not commonly requested in toxicology laboratories. Because these drugs are not frequently encountered, Volume II is a valuable reference source. For example, the pharmacokinetics, toxicity, and analysis of pancuronium is well described and in a brief study one can adequately review its pharmacology. Other peripheral toxins that are well referenced include anions (such as cyanide and nitrate), metals (such as arsenic and thallium), pesticides (such as aldrin, lindane, and paraquat), and volatiles (such as ethylene glycol and fluorocarbons) The data for each toxin include pharmacokinetics, metabolism, postmortem concentrations, and analytical approaches. while this information is provided in a brief format, adequate references are included. A very useful addition to Volume II is an appendix that contains a list of the therapeutic and toxic concentrations of common drugs in a format similar to that published by Baselt et al in Clinical Chemistry, Vol. 21, 1975, pp. 44-62. This list relates drug dose to blood and tissue concentrations and provides the clinical conditions associated with blood concentrations.
Author: J. Standefer
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1
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Book Description
The objective of the two-volume series Disposition of Toxic Drugs and Chemicals in Man is to provide reference information on the pharmacokinetics and metabolism of drugs commonly encountered in forensic and clinical practice as well as to provide useful interpretative and diagnostic information for the toxicologist. Volume I provides this information on commonly encountered centrally acting drugs while Volume II provides information on peripherally acting drugs and toxins not commonly requested in toxicology laboratories. Because these drugs are not frequently encountered, Volume II is a valuable reference source. For example, the pharmacokinetics, toxicity, and analysis of pancuronium is well described and in a brief study one can adequately review its pharmacology. Other peripheral toxins that are well referenced include anions (such as cyanide and nitrate), metals (such as arsenic and thallium), pesticides (such as aldrin, lindane, and paraquat), and volatiles (such as ethylene glycol and fluorocarbons) The data for each toxin include pharmacokinetics, metabolism, postmortem concentrations, and analytical approaches. while this information is provided in a brief format, adequate references are included. A very useful addition to Volume II is an appendix that contains a list of the therapeutic and toxic concentrations of common drugs in a format similar to that published by Baselt et al in Clinical Chemistry, Vol. 21, 1975, pp. 44-62. This list relates drug dose to blood and tissue concentrations and provides the clinical conditions associated with blood concentrations.
Author: B. Levine
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1
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Book Description
It has been over 15 years since the first edition of Baselt's "Disposition of Toxic Drugs and Chemicals in Man" was published and it is hard to imagine the practice of forensic toxicology without this valuable resource. Over the years, from the first edition to the current fourth edition, several changes have occurred. The organization of the book has changed, from a two volume set divided into centrally acting drugs and peripherally acting/other toxicants to its current alphabetical listing of toxicants. Beginning with the third edition and continuing with this edition, Robert Cravey has joined Dr. Baselt as a co-editor. Most dramatically, the number of toxic substances has more than doubled, from less than 200 in the first edition to over 400 in the fourth edition.
Author: Randall C. Baselt
Publisher:
ISBN:
Category : Drug metabolism
Languages : en
Pages : 826
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Book Description
Author: J. Standefer
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1
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Book Description
This first volume of a two-volume series presents pertinent toxicological information on more than 100 drugs ranging from ethanol to nitrous oxide. The drugs are presented alphabetically within general sections. A brief review format with citations current through 1977 includes pertinent data on drug history, metabolic parameters, structure, tissue distribution, and analytical methods. In particular, plasma concentrations, drug halflife, and urinary excretion rate following low or therapeutic doses are well delineated for most drugs. This type of reference information will be especially useful for clinical toxicologists who provide interpretive assistance to clinicians. In addition, each review includes current information on postmortem blood and tissue concentrations following overdose that will assist forensic toxicologists in their evaluations of antemortem drug abuse. Although details of methods are not included in the review, the author does provide a variety of current references to published methods for each drug.
Author: CL. Winek
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1
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Book Description
It is always a pleasure to review a new edition of a book that you have used before. Baselt's first-rate reference is now available in its fifth edition. Because of the increase in new drug entities, it is larger and the addendum to the book signals the rebirth and renewed therapeutic interest in natural supplements. Calling a drug a food supplement gets around many regulations placed on prescription and over-the-counter (OTC) drug products. Because of globalization and harmonization of drug standards, many changes are occurring in the U.S. that will allow many drug substances in their natural form to be sold as food supplements. Baselt has added an entry in the addendum on Melatonin! More will come in the sixth edition.
Author: Randall Clint Baselt
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 896
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Book Description
Discussions include occurrence and usage, blood concentrations, metabolism and excretion, toxicity, analysis and bibliographic references.
Author: PM. Kemp
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1
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Book Description
Author: RV. Blanke
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 2
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Book Description
This third edition of Baselt's indispensable compilation of data summaries and references has several welcome changes. First and foremost is the addition of another author, R. Cravey, with whom Baselt has collaborated frequently in the past. The book itself has now expanded from a 15 by 22.5-cm page size to 17.5 by 25.5 cm, with a clearer, more legible type font. The total pages have increased from 795 to 875 to accommodate a 17% increase in monographs, and 56 additional substances are discussed. The familiar red cover now bears the structure of morphine rather than that of digoxin.
Author: RH. Cravey
Publisher:
ISBN:
Category : Drugs
Languages : en
Pages : 1
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Book Description
This second edition of Disposition of Toxic Drugs and Chemicals in Man will be a welcome addition to the reference library of those involved in the analytical and interpretative aspects of forensic toxicology. It has been four years since the first edition and during that time an overwhelming number of studies have appeared in the literature on the fate of drugs and other toxic chemicals in man as well as on new methods for the analysis of these substances and their metabolites from biofluids. Dr. Baselt has thoroughly reviewed the literature and critically selected the essential information to include in each monograph.
Author: Randall C. Baselt
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Contains monographs to drug/chemical agents, alphabetically arranged. Each entry gives formula, occurrence and usage, blood concentrations, metabolism and excretion, toxicity, analysis, and references. Index.
