Author: Andrew DeWitt Baines
Publisher:
ISBN:
Category :
Languages : en
Pages : 300
Book Description
A Correlation of Structure, Function and Enzyme Activity in Regenerating Kidney Tubules
Author: Andrew DeWitt Baines
Publisher:
ISBN:
Category :
Languages : en
Pages : 300
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 300
Book Description
Circulation Research
Author:
Publisher:
ISBN:
Category : Cardiovascular system
Languages : en
Pages : 396
Book Description
Publisher:
ISBN:
Category : Cardiovascular system
Languages : en
Pages : 396
Book Description
Toxicology of the Kidney
Author: Jerry B. Hook
Publisher: CRC Press
ISBN: 9780881678857
Category : Medical
Languages : en
Pages : 588
Book Description
This second edition provides a synthesis of recent research on the mechanisms of chemically-induced kidney injury. The text includes a review of current concepts of clinical nephrotoxicity and renal failure, and mechanisms of specific classes of nephrotoxic drugs and environmental chemicals.
Publisher: CRC Press
ISBN: 9780881678857
Category : Medical
Languages : en
Pages : 588
Book Description
This second edition provides a synthesis of recent research on the mechanisms of chemically-induced kidney injury. The text includes a review of current concepts of clinical nephrotoxicity and renal failure, and mechanisms of specific classes of nephrotoxic drugs and environmental chemicals.
Canadian Theses
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 804
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 804
Book Description
Dissertation Abstracts
Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 764
Book Description
Abstracts of dissertations and monographs in microform.
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 764
Book Description
Abstracts of dissertations and monographs in microform.
Canadiana
Author:
Publisher:
ISBN:
Category : Canada
Languages : en
Pages : 1216
Book Description
Publisher:
ISBN:
Category : Canada
Languages : en
Pages : 1216
Book Description
Experimental Models for Renal Diseases
Author: G.A. Herrera
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805595387
Category : Medical
Languages : en
Pages : 381
Book Description
Our understanding of the pathogenesis of renal diseases and the ability to accurately classify and diagnose them has improved considerably over the last two decades. Until now, however, this information has not been available in a single, up-to-date and succinct yet comprehensive source. The publication at hand aims at filling this gap, condensing a vast amount of information into easily accessible chapters.After a discussion of basic concepts and principles of renal tissue reactions to injurious agents using a specific cell/compartment approach, a multitude of disorders are looked at, including renal interstitial fibrosis, glomerulosclerosis, various forms of glomerulonephritis and nephropathy, amyloidosis and renal Fanconi syndrome. Some of the chapters address controversial subjects, reporting the current situation and showing areas of future potential research interest. At the end of many of the contributions, a summary is provided, often in the form of a chart to facilitate the understanding of the information and to make it most useful for didactic purposes.This book is intended for students of various disciplines, as well as clinicians and investigators and all those trying to correlate basic research information with clinical issues.
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805595387
Category : Medical
Languages : en
Pages : 381
Book Description
Our understanding of the pathogenesis of renal diseases and the ability to accurately classify and diagnose them has improved considerably over the last two decades. Until now, however, this information has not been available in a single, up-to-date and succinct yet comprehensive source. The publication at hand aims at filling this gap, condensing a vast amount of information into easily accessible chapters.After a discussion of basic concepts and principles of renal tissue reactions to injurious agents using a specific cell/compartment approach, a multitude of disorders are looked at, including renal interstitial fibrosis, glomerulosclerosis, various forms of glomerulonephritis and nephropathy, amyloidosis and renal Fanconi syndrome. Some of the chapters address controversial subjects, reporting the current situation and showing areas of future potential research interest. At the end of many of the contributions, a summary is provided, often in the form of a chart to facilitate the understanding of the information and to make it most useful for didactic purposes.This book is intended for students of various disciplines, as well as clinicians and investigators and all those trying to correlate basic research information with clinical issues.
Research Awards Index
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1520
Book Description
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1520
Book Description
Cystogenesis
Author: Jong Hoon Park
Publisher: Springer
ISBN: 9811020418
Category : Medical
Languages : en
Pages : 128
Book Description
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.
Publisher: Springer
ISBN: 9811020418
Category : Medical
Languages : en
Pages : 128
Book Description
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.
Comprehensive Dissertation Index, 1861-1972: Biological sciences: anatomy, physiology, and genetics
Author: Xerox University Microfilms
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 984
Book Description
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 984
Book Description