A Clinician's Guide to Chemotherapy Pharmacokinetics and Pharmacodynamics PDF Download
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Author: Louise B. Grochow
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 612
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Book Description
Author: Louise B. Grochow
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 612
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Book Description
Author: William D. Figg
Publisher: Springer Science & Business Media
ISBN: 1592597343
Category : Medical
Languages : en
Pages : 623
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Book Description
Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical trial design, preclinical screening, and the development and validation of bioanalytic methods. The chapters on identifying agents to test in phase III trials and on trial design for the approval of new anticancer agents offer a unique roadmap for moving an agent to NDA submission.
Author: Federico Pea
Publisher: SEEd
ISBN: 9788897419174
Category : Medical
Languages : en
Pages : 0
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Book Description
This book is a guide for students and clinicians who want clear, useful guidance to the basic principles of pharmacokinetics and their application into clinical practice. Information on approaches to drug-dosing and monitoring in special populations are given. Charts, illustrations and examples of calculations are added.
Author: Hartmut Derendorf
Publisher: Lippincott Williams & Wilkins
ISBN: 1496385896
Category : Medical
Languages : en
Pages : 864
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Book Description
Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.
Author: Krishnaveni Manubolu
Publisher: Springer
ISBN: 9789819742820
Category : Science
Languages : en
Pages : 0
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Book Description
This book is a complete resource on pharmacokinetics, pharmacodynamics and pharmacogenomics in clinical practice. It consists of seven chapters that cover various aspects of pharmacokinetics and its clinical applications. The chapters are structured to provide clear objectives and keywords are bolded throughout the text to facilitate understanding. The topics covered include the significance of pharmacokinetics in clinical practice, factors affecting pharmacokinetic parameters, pharmacokinetic drug interactions, therapeutic drug monitoring, dosage adjustment in different population groups, the influence of hepatic diseases on pharmacokinetics and the impact of pharmacogenomics on pharmacokinetics and pharmacodynamics. The book is written in simple language to make the concepts accessible to all readers. This book is a comprehensive resource for students pursuing a doctoral degree in pharmacy, as well as academicians and researchers in clinical pharmacokinetics.
Author: Robert C. Bast, Jr.
Publisher: John Wiley & Sons
ISBN: 111900084X
Category : Medical
Languages : en
Pages : 2004
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Book Description
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author: Malcolm Rowland
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781750097
Category : Medical
Languages : en
Pages : 839
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Book Description
Rev. ed. of: Clinical pharmacokinetics. 1995.
Author: Larry A. Bauer
Publisher: McGraw Hill Professional
ISBN: 9780838503881
Category : Medical
Languages : en
Pages : 806
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Book Description
Improving upon and updating the information and format of the leading competing clinical pharmacokinetic text, Dr. Bauer, a nationally recognized leader in the field of pharmacokinetics has conceived a text for today and tomorrow's pharmacy student and practitioner. The text emphasizes the practical aspects of drug dosing for agents that have serum concentrations commonly available from clinical laboratories. Filling a hole in our list between Shargel and Schumacher, this new book will focus on patient specific drug dosing, thereby emphasizing the standard clinical pharmacokinetic dosing techniques.
Author: David J. Kerr
Publisher: Oxford University Press
ISBN: 0191065110
Category : Medical
Languages : en
Pages : 2837
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Book Description
Written and edited by internationally recognised leaders in the field, the new edition of the Oxford Textbook of Oncology has been fully revised and updated, taking into consideration the advancements in each of the major therapeutic areas, and representing the multidisciplinary management of cancer. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.
Author: Michelle A. Rudek
Publisher: Springer Science & Business Media
ISBN: 1461491355
Category : Medical
Languages : en
Pages : 828
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Book Description
There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to NDA submission Discussion of molecular targets and preclinical screening Development and validation of bioanalytical methods Chapters on clinical trial design and phase 0, I, II, III clinical trials Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents Review of the drug development process from both laboratory and clinical perspectives New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development
