Alzheimer's Disease Drug Development PDF Download
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Author: Jeffrey Cummings
Publisher: Cambridge University Press
ISBN: 1108838669
Category : Business & Economics
Languages : en
Pages : 575
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Book Description
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Author: Jeffrey Cummings
Publisher: Cambridge University Press
ISBN: 1108838669
Category : Business & Economics
Languages : en
Pages : 575
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Book Description
Provides a definitive overview of the complex ecosystem facilitating Alzheimer's Disease drug research and development. Demonstrates a drug's journey from in the lab, clinical trial testing, regulatory review, and marketing by pharmaceutical companies. Details the use of artificial intelligence, clinical trial management, and financing models.
Author: National Academies of Sciences Engineering and Medicine
Publisher:
ISBN: 9780309495035
Category :
Languages : en
Pages :
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Book Description
As the largest generation in U.S. history - the population born in the two decades immediately following World War II - enters the age of risk for cognitive impairment, growing numbers of people will experience dementia (including Alzheimer's disease and related dementias). By one estimate, nearly 14 million people in the United States will be living with dementia by 2060. Like other hardships, the experience of living with dementia can bring unexpected moments of intimacy, growth, and compassion, but these diseases also affect people's capacity to work and carry out other activities and alter their relationships with loved ones, friends, and coworkers. Those who live with and care for individuals experiencing these diseases face challenges that include physical and emotional stress, difficult changes and losses in their relationships with life partners, loss of income, and interrupted connections to other activities and friends. From a societal perspective, these diseases place substantial demands on communities and on the institutions and government entities that support people living with dementia and their families, including the health care system, the providers of direct care, and others. Nevertheless, research in the social and behavioral sciences points to possibilities for preventing or slowing the development of dementia and for substantially reducing its social and economic impacts. At the request of the National Institute on Aging of the U.S. Department of Health and Human Services, Reducing the Impact of Dementia in America assesses the contributions of research in the social and behavioral sciences and identifies a research agenda for the coming decade. This report offers a blueprint for the next decade of behavioral and social science research to reduce the negative impact of dementia for America's diverse population. Reducing the Impact of Dementia in America calls for research that addresses the causes and solutions for disparities in both developing dementia and receiving adequate treatment and support. It calls for research that sets goals meaningful not just for scientists but for people living with dementia and those who support them as well. By 2030, an estimated 8.5 million Americans will have Alzheimer's disease and many more will have other forms of dementia. Through identifying priorities social and behavioral science research and recommending ways in which they can be pursued in a coordinated fashion, Reducing the Impact of Dementia in America will help produce research that improves the lives of all those affected by dementia.
Author: Daniel Gibbs
Publisher: Cambridge University Press
ISBN: 1009333585
Category : Medical
Languages : en
Pages : 227
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Book Description
Dr Daniel Gibbs is one of 50 million people worldwide with an Alzheimer's disease diagnosis. Unlike most patients with Alzheimer's, however, Dr Gibbs worked as a neurologist for twenty-five years, caring for patients with the very disease now affecting him. Also unusual is that Dr Gibbs had begun to suspect he had Alzheimer's several years before any official diagnosis could be made. Forewarned by genetic testing showing he carried alleles that increased the risk of developing the disease, he noticed symptoms of mild cognitive impairment long before any tests would have alerted him. In this highly personal account, Dr Gibbs documents the effect his diagnosis has had on his life and explains his advocacy for improving early recognition of Alzheimer's. Weaving clinical knowledge from decades caring for dementia patients with his personal experience of the disease, this is an optimistic tale of one man's journey with early-stage Alzheimer's disease. Soon to be a documentary film on MTV/Paramount +.
Author: National Academies of Sciences Engineering and Medicine
Publisher:
ISBN: 9780309684736
Category :
Languages : en
Pages :
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Book Description
Author: Michelle Braun
Publisher: Union Square + ORM
ISBN: 1454937793
Category : Self-Help
Languages : en
Pages : 200
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Book Description
From a Harvard- and Yale-trained neuropsychologist, a science-backed five-step program to boost memory and dramatically decrease the risk of Alzheimer’s. American adults fear Alzheimer’s more than any other disease—including cancer—and because many don’t realize there is no genetic cause for 99 percent of Alzheimer’s cases, they don’t take the necessary steps to change lifestyle factors shown to significantly protect against the disease. In this book, board-certified neuropsychologist Dr. Michelle Braun inspires you to make lasting improvements by explaining the truth about brain health and providing expert guidance through the maze of conflicting media advice on supplements, brain games, nutrition, and exercise. Braun interviews eight leading brain health experts, combining their insights with cutting-edge research to offer proven strategies to implement the five steps of the High-Octane Brain. Interactive exercises help you develop a personalized program for optimal brain health. Dr. Braun also provides a tracking system with a visual depiction of progress, and shows the High-Octane Brain plan in action through the lives of clients. Packed with valuable tips you can implement immediately to minimize common “brain blips,” exercises to boost your memory within minutes, and inspiring insights from nine High-Octane Brain role models ages 44 to 103, this groundbreaking book helps put the future of your brain in your control. “Thorough, backed up by the best available research, and accessible.” —Barry Gordon, M.D., Ph.D., Director, Cognitive Neurology/Neuropsychology Division, Department of Neurology, Johns Hopkins Medical Institutions and University
Author: Lauren A. Yates
Publisher: Routledge
ISBN: 1351805460
Category : Psychology
Languages : en
Pages : 294
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Book Description
Cognitive Stimulation Therapy (CST) has made a huge global, clinical impact since its inception, and this landmark book is the first to draw all the published research together in one place. Edited by experts in the intervention, including members of the workgroup who initially developed the therapy, Cognitive Stimulation Therapy for Dementia features contributions from authors across the globe, providing a broad overview of the entire research programme. The book demonstrates how CST can significantly improve cognition and quality of life for people with dementia, and offers insight on the theory and mechanisms of change, as well as discussion of the practical implementation of CST in a range of clinical settings. Drawing from several research studies, the book also includes a section on culturally adapting and translating CST, with case studies from countries such as Japan, New Zealand and Sub-Saharan Africa. Cognitive Stimulation Therapy for Dementia will be essential reading for academics, researchers and postgraduate students involved in the study of dementia, gerontology and cognitive rehabilitation. It will also be of interest to health professionals, including psychologists, psychiatrists, occupational therapists, nurses and social workers.
Author: Arlene Astell
Publisher: Jessica Kingsley Publishers
ISBN: 1784507792
Category : Health & Fitness
Languages : en
Pages : 234
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Book Description
Many new pieces of technology can be beneficial to individuals living with dementia, including both hardware and software. This straightforward guide summarises the current research on this growing topic, and gives practical advice on how available technology can be used to improve the everyday lives of people with dementia. Looking at a range of available products, such as off-the-shelf computers and smartphones, to dementia specific applications and programs, it also addresses some common obstacles and barriers faced when introducing technology in dementia care. The past twenty years have seen an array of technologies developed to improve the day-to-day lives of people with dementia; this guide shows how they can be effectively used.
Author: Maria Shriver
Publisher: Free Press
ISBN: 9781451639872
Category : Health & Fitness
Languages : en
Pages : 0
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Book Description
The Shriver Report: A Woman’s Nation Takes on Alzheimer’s will be the first comprehensive multi-disciplinary look at these questions at this transformational moment. The Report will digest the current trends in thinking about Alzheimer’s, examine cutting-edge medical research, look at societal impacts, and include a groundbreaking and comprehensive national poll. It will feature original photography and personal essays by men and women – some from the public arena with names you know, some from everyday America – sharing their personal struggles with the disease as patients, caregivers and family members.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309459591
Category : Medical
Languages : en
Pages : 181
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Book Description
Societies around the world are concerned about dementia and the other forms of cognitive impairment that affect many older adults. We now know that brain changes typically begin years before people show symptoms, which suggests a window of opportunity to prevent or delay the onset of these conditions. Emerging evidence that the prevalence of dementia is declining in high-income countries offers hope that public health interventions will be effective in preventing or delaying cognitive impairments. Until recently, the research and clinical communities have focused primarily on understanding and treating these conditions after they have developed. Thus, the evidence base on how to prevent or delay these conditions has been limited at best, despite the many claims of success made in popular media and advertising. Today, however, a growing body of prevention research is emerging. Preventing Cognitive Decline and Dementia: A Way Forward assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. This report provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging.
Author: Jeffrey L. Cummings
Publisher: Oxford University Press
ISBN: 0190233567
Category : Medical
Languages : en
Pages : 361
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Book Description
Presents a thorough examination of the unifying principles from the subcellular to the systems and clinical levels; Identifies common themes among molecular biology, genetics, physiology, pathology, biomarkers, behavior, and treatment strategies that are shared between neurodegenerative diseases; Enables better care of patients and help build collaboration across researchers in multiple specializations that could help advance future insights and facilitate novel therapies and enhancing basic scientific understanding of these diseases to a new generation.
