How and why We Age

How and why We Age PDF Author: Leonard Hayflick
Publisher:
ISBN: 9780345401557
Category : Aging
Languages : en
Pages : 0

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Book Description
"How long can humans live? Is immortality possible? Just what is the aging process? The aging and inevitable death of the human body have inspired more myths and outrageous quackery than anything else subject to scientific inquiry. . . . Now comes a most fascinating book, insightful and scholarly, to provide what answers have emerged so far." --San Francisco Chronicle Here, at last, preeminent cell biologist Leonard Hayflick presents the truth about human aging. Based on more than thirty years of pioneering research in the field, How and Why We Age explores not only how our major biological systems change as we grow older, but also examines the intangible alterations in our modes of thinking and feeling, our moods and sexual desires, our personality traits and our memories. With the immediacy of the latest scientific discoveries, Dr. Hayflick explains how aging affects every part of the body, and dispels many of the most persistent aging myths, to show that: * Hearts do not naturally get weaker with age. * Regular exercise and a low-fat diet won't slow aging. * Curing cancer would only add two years to the average sixty-five-year-old American life. Curing heart disease, however would add fourteen years. * Only five percent of people over the age of sixty-five are in nursing homes * No human has lived--or probably can live--past 120 years. Gracefully written, clearly organized, and packed with essential facts and statistics, How and Why We Age is a landmark study of the aging process for readers of all ages. "Written in clear, nontechnical language, it is an excellent introduction to the scientific and demographic literature on this multifacetedsubject." --Nature

How and why We Age

How and why We Age PDF Author: Leonard Hayflick
Publisher:
ISBN: 9780345401557
Category : Aging
Languages : en
Pages : 0

Get Book Here

Book Description
"How long can humans live? Is immortality possible? Just what is the aging process? The aging and inevitable death of the human body have inspired more myths and outrageous quackery than anything else subject to scientific inquiry. . . . Now comes a most fascinating book, insightful and scholarly, to provide what answers have emerged so far." --San Francisco Chronicle Here, at last, preeminent cell biologist Leonard Hayflick presents the truth about human aging. Based on more than thirty years of pioneering research in the field, How and Why We Age explores not only how our major biological systems change as we grow older, but also examines the intangible alterations in our modes of thinking and feeling, our moods and sexual desires, our personality traits and our memories. With the immediacy of the latest scientific discoveries, Dr. Hayflick explains how aging affects every part of the body, and dispels many of the most persistent aging myths, to show that: * Hearts do not naturally get weaker with age. * Regular exercise and a low-fat diet won't slow aging. * Curing cancer would only add two years to the average sixty-five-year-old American life. Curing heart disease, however would add fourteen years. * Only five percent of people over the age of sixty-five are in nursing homes * No human has lived--or probably can live--past 120 years. Gracefully written, clearly organized, and packed with essential facts and statistics, How and Why We Age is a landmark study of the aging process for readers of all ages. "Written in clear, nontechnical language, it is an excellent introduction to the scientific and demographic literature on this multifacetedsubject." --Nature

Why We Age

Why We Age PDF Author: Steven N. Austad
Publisher: Wiley
ISBN: 9780471296461
Category : Science
Languages : en
Pages : 0

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Book Description
Why has the life span of the average American increased from 48 to 75 years in this century alone? . . . If the body is a machine that simply wears out, why do some cells seem immortal? . . . Is there an aging gene? And can we control it? . . . Can antioxidants and hormone therapy actually slow the aging process and extend life? Steven Austad s compelling book investigates the history, the theories, and the personalities behind the quest to understand the nature of aging. Here is hard evidence from the front lines of research that science is finally closing in on the fundamental processes of human biology and life. "Austad s book can be read with pleasure and profit by any intelligent person with a smattering of biological knowledge." Science "In this clear, engrossing overview, Austad takes the sting out of a subject that will ultimately capture us all." Publishers Weekly "Why We Age is remarkably rigorous in its analysis and thorough scope. . . . A comprehensive examination of its topic." Science Editors, Amazon.com "The problem with long life is that one keeps getting older; here s an able and clearly written summary of the latest theories on why we age and what might be done to ameliorate the process." Kirkus Reviews

Lifespan

Lifespan PDF Author: David A. Sinclair
Publisher: Atria Books
ISBN: 1501191977
Category : Science
Languages : en
Pages : 432

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Book Description
A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

Ageless

Ageless PDF Author: Andrew Steele
Publisher: Anchor
ISBN: 0385544936
Category : Science
Languages : en
Pages : 353

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Book Description
“A fascinating look at how scientists are working to help doctors treat the aging process itself, helping us all to lead longer, healthier lives.” —Sanjay Gupta, MD Aging—not cancer, not heart disease—is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: there are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are, a phenomenon known as “biological immortality.” In Ageless, Andrew Steelecharts the astounding progress science has made in recent years to secure the same for humans: to help us become old without getting frail, to live longer without ill health or disease.

Epigenetics of Aging

Epigenetics of Aging PDF Author: Trygve O. Tollefsbol
Publisher: Springer Science & Business Media
ISBN: 1441906398
Category : Medical
Languages : en
Pages : 462

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Book Description
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Toward Healthy Aging

Toward Healthy Aging PDF Author: Priscilla Ebersole
Publisher: Mosby Incorporated
ISBN: 9780323047302
Category : Medical
Languages : en
Pages : 727

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Book Description
As the most comprehensive resource on health promotion and maintenance for older adults and their families and caregivers, Toward Healthy Aging, 7th Edition includes the most current information you need to provide effective holistic care, promote healthy lifestyle choices, and address end-of-life issues. Grounded in the core competencies recommended by the AACN in collaboration with the Hartfound Institute for Geriatric Nursing and using Maslow's hierarchy of needs, this book includes complete coverage of both common and uncommon conditions in the older adult. Towards Healthy Aging also highlights key aging issues with sections devoted to basic physiologic needs, safety and security, the need to belong, self-esteem, and self-actualization. A strong focus on health and wellness emphasizes a positive approach to aging. Disease processes are discussed in the context of healthy adaptation, nursing support, and responsibilities. Careful attention to age, cultural, and gender differences are integrated throughout to help you remember these important considerations when caring for older adults. Up-to-date content on AIDS provides important information on addressing this growing concern among older adults. Consistent chapter is organization with objectives, case studies, critical thinking questions, research, and study questions make information easy to find and use. Assessment guidelines are incorporated throughout in helpful tables, boxes, and forms for quick access. Case studies at the end of most chapters explore realistic patient care scenarios to help you expand your knowledge and understanding. Resource lists and appendices provide opportunities for further research and study. With over 200 illustrations, the full-color design is engaging and easy to read. Healthy People 2010 boxes address healthy aging considerations. Evidence-Based Practice boxes help you incorporate the latest research findings into practice and advise you on how to avoid potentially harmful practices. A Nutritional Needs chapter includes the most current nutritional guidelines for older adults to help you better address patients' nutritional needs. Includes the latest scales and guidelines for assessing the gerontologic patient in the Health Assessment in Gerontological Nursing chapter. Expanded coverage of end-of-life issues helps you meet the needs of older adults and their families and caregivers during this difficult transition. Economics of aging discussions help you better understand the financial challenges your patients may face. The latest pharmacologic and nonpharmacologic pain management information helps you reduce pain and discomfort for your patients and helps you provide more effective care.

What's Age Got To Do With It?

What's Age Got To Do With It? PDF Author: Louise Morse
Publisher: Monarch Books
ISBN: 0857217496
Category : Religion
Languages : en
Pages : 176

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Book Description
If you think that being old is about having a rocking chair and an easy life style, think again. You're looking through the binoculars backwards. What's Age Got To Do With It? turns the lenses the right way around and gives a clear, Scriptural view of God's purpose for old age. When He created the universe, God set in motion times and seasons and the ageing process. Old age was part of His plan from the beginning - that people should ripen to maturity, developing wisdom through a lifetime of experience and relationship with Him, eventually enriching others with attributes that have been honed over lifetimes. But instead of contributing as God intended, many see themselves as "useless" and are afraid of being a burden. Ageism has destroyed their self-image and expectations, and they give up and become passive - and we are all the losers. Here are stories of many people living full, purpose-driven lives well into their 90s and even 100s. For example, you'll meet the lay preacher who wrote a book at 100 years of age because he couldn't stand long enough to preach, and the 95-year-old who organized more Christian support from local churches for his care home, as well as many ordinary people who are making a difference to the lives of those around them. What's Age Got To Do With It? shows how to take off the reins and live the way God intended from the beginning.

Age Studies

Age Studies PDF Author: Susan Pickard
Publisher: SAGE
ISBN: 1473958970
Category : Social Science
Languages : en
Pages : 313

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Book Description
"With great rigour, yet an enviable lightness of touch, Susan Pickard has written an engaging and accessible book that students will love." - Rosaline Gill, City University London "A scholarly tour de force that brings into focus the various disciplines, histories, literatures and knowledges that have transformed us into modern subjects of age." - Stephen Katz, Trent University Age Studies takes an invigorating approach to the study of age and ageing in contemporary society. Encompassing ageing throughout the life course, taking in childhood, adolescence, mid-life and older age, and situated explicitly within a sociological disciplinary framework, Age Studies: Explores current social science debates on the study of ageing linking these to core sociological concepts. Links theory and application, using a variety of examples and international case studies Includes chapter summaries, further reading and guided questions. A thought-provoking companion to advanced undergraduates and postgraduate student studying ageing, older people, social gerontology and related courses.

Evolutionary Gerontology and Geriatrics

Evolutionary Gerontology and Geriatrics PDF Author: Giacinto Libertini
Publisher: Springer Nature
ISBN: 3030737748
Category : Social Science
Languages : en
Pages : 426

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Book Description
This book provides concrete scientific basis that we can conceive the possibility of modifying or even completely canceling aging process, despite the fact that aging is commonly regarded as the result of the overall effects of many uncontrollable degenerative phenomena. The authors illustrate in detail the mechanisms by which cells and the whole organism age. Actions by which it is possible, or will be possible within a limited time, to operate for modifying aging are also debated. The discussion is conducted within the frame and the concepts of evolutionary medicine, which is also indispensable for distinguishing between the manifestations of aging and: (i) diseases that worsen with age, and (ii) acceleration of normal aging rates, caused by unhealthy lifestyle habits and other avoidable factors. The book also discusses the impact of aging on overall mortality and the strange situation that, according to official statistics, aging does not exist as cause of death. This book is a turning point between a gerontology and geriatrics conceived as the study and vain treatment of an incurable condition and one in which these disciplines examine the how and why of a physiological phenomenon that can be modified up to a possible total control. This means transforming the medical prevention and treatment of physiological aging from the greatest failure to the greatest success of medicine.

Perioperative Care of the Elderly

Perioperative Care of the Elderly PDF Author: Gabriella Bettelli
Publisher: Cambridge University Press
ISBN: 1108166784
Category : Medical
Languages : en
Pages : 386

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Book Description
This innovative, comprehensive book covers the key elements of perioperative management of older patients. The book's chapter structure coincides with the clinical path patients tread during their treatment, from preoperative evaluation to post-hospital care. Epidemiological aspects and aging processes are illustrated, providing keys to understanding the quick expansion of geriatric surgery and defining the clinical profile of older surgical patients in a cybernetic perspective. Preoperative evaluation and preparation for surgery, including medication reconciliation and pre-habilitation, are developed in the light of supporting decision-making about surgery in an evidence-based and patient-focused way. Intra- and postoperative management are discussed, aiming to tailor anesthetic, surgical and nursing approaches to specific patients' needs, in order to prevent both general and age-related complications. This volume also addresses issues relevant to geriatric surgery, from different organizational models to clinical risk management and systems engineering applied to hospital organization.