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Author: James Bassingthwaighte
Publisher: Springer Science & Business Media
ISBN: 1461221846
Category : Medical
Languages : en
Pages : 576
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Book Description
The field of capillary-tissue exchange physiology has been galvanized twice in the past 25 years. A 1969 conference at the National Academy of Sciences in Copenhagen resulted in the book Capillary Permeability: The Transfer of Mole cules and Ions Between the Capillary Blood and the Tissue (Crone and Lassen, 1970). It focused on the physiochemical aspects of transcapillary water and solute transport. The field has matured considerably since. This volume was designed as the successor to the 1970 book, and was created at a gathering of the authors at McGill University. It too captures the breadth of a field that has been dramatically enriched by numerous technical and conceptual advances. In 1970 it was already known that the capillary wall was not merely a "cellophane bag" exerting steric hindrances on solute particles. Instead, the endothelial surface was recognized as the site of binding reactions and permeation by passive or carrier-mediated trans port. Furthermore, the cells of the blood could traverse evanescent wide openings in the "zippered" clefts. Today, research priorities have turned more to cell-cell interactions, toward understanding the utility of the gap junctional connections between endothelial cells and neighboring smooth muscle cells, neuronal twigs, and the parenchymal cells of organs. New discoveries in the past few years have revealed the critical importance of the close relationships between the endothelial cells and the parenchymal cells.
Author: James Bassingthwaighte
Publisher: Springer Science & Business Media
ISBN: 1461221846
Category : Medical
Languages : en
Pages : 576
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Book Description
The field of capillary-tissue exchange physiology has been galvanized twice in the past 25 years. A 1969 conference at the National Academy of Sciences in Copenhagen resulted in the book Capillary Permeability: The Transfer of Mole cules and Ions Between the Capillary Blood and the Tissue (Crone and Lassen, 1970). It focused on the physiochemical aspects of transcapillary water and solute transport. The field has matured considerably since. This volume was designed as the successor to the 1970 book, and was created at a gathering of the authors at McGill University. It too captures the breadth of a field that has been dramatically enriched by numerous technical and conceptual advances. In 1970 it was already known that the capillary wall was not merely a "cellophane bag" exerting steric hindrances on solute particles. Instead, the endothelial surface was recognized as the site of binding reactions and permeation by passive or carrier-mediated trans port. Furthermore, the cells of the blood could traverse evanescent wide openings in the "zippered" clefts. Today, research priorities have turned more to cell-cell interactions, toward understanding the utility of the gap junctional connections between endothelial cells and neighboring smooth muscle cells, neuronal twigs, and the parenchymal cells of organs. New discoveries in the past few years have revealed the critical importance of the close relationships between the endothelial cells and the parenchymal cells.
Author:
Publisher:
ISBN: 9780815332183
Category : Cells
Languages : en
Pages : 0
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Book Description
Author: Roland N. Pittman
Publisher: Biota Publishing
ISBN: 1615047212
Category : Medical
Languages : en
Pages : 117
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Book Description
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Author: Juergen Eckel
Publisher: Academic Press
ISBN: 0128097191
Category : Science
Languages : en
Pages : 242
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Book Description
The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health and disease. Communication between different organs involves lipids and other small molecules and a host of proteins and peptides comprising the secretome of different organs (organokinome). More than 600 adipokines have been identified, and an increasing number of hepatokines and myokines have recently been discovered with mostly unknown physiological impact. Importantly, an aberrant signature of the organokinome may be critically underlying a variety of metabolic diseases and may determine the individual susceptibility to disease development. - Summarizes our current knowledge on the secretome of different cells and tissues - Dissects auto-, para- and endocrine functions of major secreted peptides and proteins - Analyzes the secretory malfunction of different cells and its impact for disease development - Authored by a leader in the field, presenting a coherent view on this very complex topic
Author: Julianne Zedalis
Publisher:
ISBN: 9781947172401
Category : Biology
Languages : en
Pages : 1923
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Book Description
Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.
Author: Joseph D. Bronzino
Publisher: CRC Press
ISBN: 1439825319
Category : Medical
Languages : en
Pages : 1830
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Book Description
Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine. More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, noninvasive targeted protein and peptide drug delivery, cardiac valve prostheses, blood substitutes, artificial skin, molecular diagnostics in personalized medicine, and bioethics.
Author: L.E. Feinendegen
Publisher: Springer Science & Business Media
ISBN: 364255539X
Category : Medical
Languages : en
Pages : 795
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Book Description
Biochemical transparency of the human body is at the doorstep of advanced technology. Toward this goal the book describes relevant isotopic tracer techniques of nuclear medicine. It deals with quantitatively measuring in vivo biochemical reactions as they occur within homeostatic circuits under control by genes and protein interactions. The text indicates how nuclear medicine can aid clinical researchers and practitioners, human geneticists and pharmacologists in understanding (and affecting) gene-phenotype relationships. Experts give background, techniques and examples in an interdisciplinary approach to regional imaging and in vitro analyses of biochemical reactions.
Author: Robert A. Peattie
Publisher: CRC Press
ISBN: 1439874638
Category : Medical
Languages : en
Pages : 195
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Book Description
Design, analysis and simulation of tissue constructs is an integral part of the ever-evolving field of biomedical engineering. The study of reaction kinetics, particularly when coupled with complex physical phenomena such as the transport of heat, mass and momentum, is required to determine or predict performance of biologically-based systems wheth
Author: Andras Eke
Publisher: Springer Science & Business Media
ISBN: 9780306462818
Category : Science
Languages : en
Pages : 842
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Book Description
The International Society on Oxygen Transport to Tissue (lSOTT) held its 26th annual meeting from August 23-26, 1998, and met for the second time in Budapest. As captured in the design of the ISOTT'98 logo, the venue of the conference was the Budapest Hilton in the heart of the historic Castle District in Buda, across from Hungary's coronation church-the Matthias Church-and the fairy-tale-like Fisherman's Bastion; a special place with a historical touch situated atop the Castle Hill, from where participants enjoyed the spectacular panoramic views of Budapest exquisitely laid out on both sides of the Danube. In preparation for ISOTT'98, major emphasis was given to the application of informatics in collecting, presenting, and disseminating scientific and other information associated with the meeting. Electronic submission of the abstracts made it possible to publish the illustrated Abstracts on the ISOTT'98 Web Site well before the meeting. Following the meeting, an ISOTT'98 CD was published as a digital, searchable record of ISOTT'98. The scientific program was designed with the active participation of prospective attendees, in that priority and momentum was given to the topics selected by those visiting the Web Site. Poster and oral presentations were considered as equivalently effective formats, reflected by the fact that posters were on display throughout the meeting.
Author: Joseph D. Bronzino
Publisher: CRC Press
ISBN: 9780849321238
Category : Medical
Languages : en
Pages : 1328
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Book Description
Over the last century, medicine has come out of the "black bag" and emerged as one of the most dynamic and advanced fields of development in science and technology. Today, biomedical engineering plays a critical role in patient diagnosis, care, and rehabilitation. As such, the field encompasses a wide range of disciplines, from biology and physiology to material science and nanotechnology. Reflecting the enormous growth and change in biomedical engineering during the infancy of the 21st century, The Biomedical Engineering Handbook enters its third edition as a set of three carefully focused and conveniently organized books. Reviewing applications at the leading edge of modern biomedical engineering, Tissue Engineering and Artificial Organs explores transport phenomena, biomimetics systems, biotechnology, prostheses, artificial organs, and ethical issues. The book features approximately 90% new material in the tissue engineering section, integrates coverage of life sciences with a new section on molecular biology, and includes a new section on bionanotechnology. Prominent leaders from around the world share their expertise in their respective fields with many new and updated chapters. New technologies and methods spawned by biomedical engineering have the potential to improve the quality of life for everyone, and Tissue Engineering and Artificial Organs sheds light on the tools that will enable these advances.
