Volunteers in Research and Testing

Volunteers in Research and Testing PDF Author: Bryony Close
Publisher: CRC Press
ISBN: 0203211898
Category : Medical
Languages : en
Pages : 194

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Book Description
This text discusses the use of volunteers, either healthy or undergoing treatment, in the research and testing of medicinal and non-medicinal products. The extent to which the improved use of such volunteers could reduce the need for animal tests is

Volunteers in Research and Testing

Volunteers in Research and Testing PDF Author: Bryony Close
Publisher: CRC Press
ISBN: 0203211898
Category : Medical
Languages : en
Pages : 194

Get Book Here

Book Description
This text discusses the use of volunteers, either healthy or undergoing treatment, in the research and testing of medicinal and non-medicinal products. The extent to which the improved use of such volunteers could reduce the need for animal tests is

Ethics Dumping

Ethics Dumping PDF Author: Doris Schroeder
Publisher: Springer
ISBN: 3319647318
Category : Philosophy
Languages : en
Pages : 144

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Book Description
This open access book provides original, up-to-date case studies of “ethics dumping” that were largely facilitated by loopholes in the ethics governance of low and middle-income countries. It is instructive even to experienced researchers since it provides a voice to vulnerable populations from the fore mentioned countries. Ensuring the ethical conduct of North-South collaborations in research is a process fraught with difficulties. The background conditions under which such collaborations take place include extreme differentials in available income and power, as well as a past history of colonialism, while differences in culture can add a new layer of complications. In this context, up-to-date case studies of unethical conduct are essential for research ethics training.

Clinical Trials

Clinical Trials PDF Author: Lorna Speid, Ph.D
Publisher: Oxford University Press
ISBN: 0199750599
Category : Medical
Languages : en
Pages : 201

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Book Description
Every year, hundreds of thousands of healthy volunteers and patients worldwide undertake the journey through the maze that can be clinical trials. Research participants take part in clinical trials for a variety of reasons. The healthy volunteers may be seeking extra money to pay off college tuition, or they may know someone who is suffering and would potentially benefit from the results of the trial. The patient who is terminally ill might participate in a clinical trial simply as a last hope for a cure. Whatever the goals, though, most participants will experience the same sense of bewilderment as they encounter the jargon and medical terminology that they will hear and have to read about and understand during the course of the clinical trial. Clinical Trials: What Patients and Volunteers Need to Know demystifies the entire process, focusing on the process of drug development, and the clinical trial itself. Writing from a lifetime of experience, the author provides important questions to ask those running a clinical trial, key definitions and terms for a participant to know and understand, as well as anecdotes illustrating the clinical trial process. The author also grapples with the idea of "informed consent," providing mechanisms for patients and volunteers to feel fully informed before signing up for the trial. A vital resource for those who are considering enrolling in a clinical trial, or for the parents, friends, or relatives of those involved in a clinical trial, this book takes away the mystery and allows the participant to enter a clinical trial feeling both informed and confident.

Veterans at Risk

Veterans at Risk PDF Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030904832X
Category : Medical
Languages : en
Pages : 448

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Book Description
Recently, World War II veterans have come forward to claim compensation for health effects they say were caused by their participation in chemical warfare experiments. In response, the Veterans Administration asked the Institute of Medicine to study the issue. Based on a literature review and personal testimony from more than 250 affected veterans, this new volume discusses in detail the development and chemistry of mustard agents and Lewisite followed by interesting and informative discussions about these substances and their possible connection to a range of health problems, from cancer to reproductive disorders. The volume also offers an often chilling historical examination of the use of volunteers in chemical warfare experiments by the U.S. militaryâ€"what the then-young soldiers were told prior to the experiments, how they were "encouraged" to remain in the program, and how they were treated afterward. This comprehensive and controversial book will be of importance to policymakers and legislators, military and civilian planners, officials at the Department of Veterans Affairs, military historians, and researchers.

Volunteers

Volunteers PDF Author: Marc A. Musick
Publisher: Indiana University Press
ISBN: 0253116864
Category : Social Science
Languages : en
Pages : 681

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Book Description
Who tends to volunteer and why? What causes attract certain types of volunteers? What motivates people to volunteer? How can volunteers be persuaded to continue their service? Making use of a broad range of survey information to offer a detailed portrait of the volunteer in America, Volunteers provides an important resource for everyone who works with volunteers or is interested in their role in contemporary society. Mark A. Musick and John Wilson address issues of volunteer motivation by focusing on individuals' subjective states, their available resources, and the influence of gender and race. In a section on social context, they reveal how volunteer work is influenced by family relationships and obligations through the impact of schools, churches, and communities. They consider cross-national differences in volunteering and historical trends, and close with consideration of the research on the organization of volunteer work and the consequences of volunteering for the volunteer.

Clinical Trials in Osteoporosis

Clinical Trials in Osteoporosis PDF Author: Derek Pearson
Publisher: Springer Science & Business Media
ISBN: 1846285879
Category : Medical
Languages : en
Pages : 294

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Book Description
This second revised and updated edition is a practical handbook on clinical trials in the growing field of osteoporosis. Topics covered include study design, technical issues, data collection, quality assurance, data analysis, and presentation. Clinical Trials in Osteoporosis takes the user through the process step-by-step from start to finish. It also provides a background on regulatory guidelines, ethical implications, endpoints, current therapies, and the ideal drug to use. It will serve as a practical manual for clinicians and scientists new to the subject and provide a standard for existing centers to measure themselves against.

Adverse Events

Adverse Events PDF Author: Jill A. Fisher
Publisher: NYU Press
ISBN: 1479877999
Category : Social Science
Languages : en
Pages : 328

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Book Description
Winner, 2022 Donald W. Light Award for Applied Medical Sociology, given by the Medical Sociology Section of the American Sociological Association Winner, 2021 Robert K. Merton Book Award, given by the Science, Knowledge, and Technology Section of the American Sociological Association 2021 Outstanding Academic Title, Choice Magazine Explores the social inequality of clinical drug testing and its effects on scientific results Imagine that you volunteer for the clinical trial of an experimental drug. The only direct benefit of participating is that you will receive up to $5,175. You must spend twenty nights literally locked in a research facility. You will be told what to eat, when to eat, and when to sleep. You will share a bedroom with several strangers. Who are you, and why would you choose to take part in this kind of study? This book explores the hidden world of pharmaceutical testing on healthy volunteers. Drawing on two years of fieldwork in clinics across the country and 268 interviews with participants and staff, it illustrates how decisions to take part in such studies are often influenced by poverty and lack of employment opportunities. It shows that healthy participants are typically recruited from African American and Latino/a communities, and that they are often serial participants, who obtain a significant portion of their income from these trials. This book reveals not only how social inequality fundamentally shapes these drug trials, but it also depicts the important validity concerns inherent in this mode of testing new pharmaceuticals. These highly controlled studies bear little resemblance to real-world conditions, and everyone involved is incentivized to game the system, ultimately making new drugs appear safer than they really are. Adverse Events provides an unprecedented view of the intersection of racial inequalities with pharmaceutical testing, signaling the dangers of this research enterprise to both social justice and public health.

Undergraduate Research in the Sciences

Undergraduate Research in the Sciences PDF Author: Sandra Laursen
Publisher: John Wiley & Sons
ISBN: 0470625635
Category : Education
Languages : en
Pages : 320

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Book Description
Undergraduate research enhances the learning experience of students in science, technology, engineering, and mathematics. Undergraduate Research in the Sciences offers a groundbreaking and practical research-based book on the topic. This comprehensive resource addresses how undergraduate research benefits undergraduate participants, including those populations that are underrepresented in the sciences; compares its benefits with other types of educational activities and experiences; and assesses its long-term value to students and faculty as both a scholarly and educational endeavor. In laying out the processes by which these benefits are achieved, this important book can assist faculty and program directors with practical guidance for design and evaluation of both new and existing undergraduate research programs. Praise for Undergraduate Research in the Sciences "This meticulous, definitive study of the effects of working with a faculty member on research as an undergraduate confirms the overall value of the experience by taking us deep into the minds and actions of participants—both faculty and students. As a result we now have many more compelling reasons to get more students involved with research mentors and ways to optimize the benefits for all parties."—George D. Kuh, Chancellor's Professor and director, Indiana University Center for Postsecondary Research "This timely book offers a unique, comprehensive analysis of undergraduate research in the sciences, based on the voices of college students and faculty mentors who have participated in these voyages of discovery. As our nation struggles to train more scientists, this book will be a valuable resource for designing undergraduate research experiences that can build our country's capacity for discovery and innovation."—Arthur B. Ellis, Vice Chancellor for Research, University of California, San Diego "The text is written in a lucid and engaging style and will be a valuable guide to policymakers, academic administrators, and faculty members who want to find ways to engage undergraduates in the 'real work' of investigation."—Judith A. Ramaley, president, Winona State University "This book is a 'must-read' for anyone who directs undergraduates in research. It presents an impressive and rigorous body of work that brings fresh insights into the field of undergraduate research. The next generation of scientists will benefit greatly from the findings and recommendations!"—Jo Handelsman, Howard Hughes Medical Institute Professor, Yale University

Anticancer Drug Development

Anticancer Drug Development PDF Author: Bruce C. Baguley
Publisher: Elsevier
ISBN: 0080490441
Category : Medical
Languages : en
Pages : 411

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Book Description
Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. - One work that can be consulted for all aspects of anticancer drug development - Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts - A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death - Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products - Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques - Hundreds of references that allow the reader to access relevant scientific and medical literature - Clear illustrations, some in color, that provide both understanding of the field and material for teaching

Female Employment and Gender Gaps in China

Female Employment and Gender Gaps in China PDF Author: Xinxin Ma
Publisher: Springer Nature
ISBN: 9813369043
Category : Business & Economics
Languages : en
Pages : 190

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Book Description
This open access book investigates female employment and the gender gap in the labor market and households during China’s economic transition period. It provides the reader with academic evidence for understanding the mechanism of female labor force participation, the determinants of the gender gap in the labor market, and the impact of policy transformation on women’s wages and employment in China from an economics perspective. The main content of this book includes three parts―women’s family responsibilities and women’s labor supply (child care, parent care, and women’s employment), the gender gap in the labor market and society (gender gaps in wages, Communist Party membership, and participation in social activity), and the impacts of policy transformation on women’s wages and employment (the social security system and the educational expansion policy on women’s wages and employment) in China. This book provides academic evidence about these issues based on economics theories and econometric analysis methods using many kinds of long-term Chinese national survey data. This book is highly recommended to readers who are interested in up-to-date and in-depth empirical studies of the gender gap and women’s employment in China during the economic transition period. This book is of interest to various groups such as readers who are interested in the Chinese economy, policymakers, and scholars with econometric analysis backgrounds.