Bioinformatics for Geneticists

Bioinformatics for Geneticists PDF Author: Michael R. Barnes
Publisher: John Wiley & Sons
ISBN: 0470026197
Category : Science
Languages : en
Pages : 577

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Book Description
Praise from the reviews: "Without reservation, I endorse this text as the best resource I've encountered that neatly introduces and summarizes many points I've learned through years of experience. The gems of truth found in this book will serve well those who wish to apply bioinformatics in their daily work, as well as help them advise others in this capacity." CIRCGENETICS "This book may really help to get geneticists and bioinformaticians on 'speaking-terms'... contains some essential reading for almost any person working in the field of molecular genetics." EUROPEAN JOURNAL OF HUMAN GENETICS "... an excellent resource... this book should ensure that any researcher's skill base is maintained." GENETICAL RESEARCH “… one of the best available and most accessible texts on bioinformatics and genetics in the postgenome age… The writing is clear, with succinct subsections within each chapter….Without reservation, I endorse this text as the best resource I’ve encountered that neatly introduces and summarizes many points I’ve learned through years of experience. The gems of truth found in this book will serve well those who wish to apply bioinformatics in their daily work, as well as help them advise others in this capacity.” CIRCULATION: CARDIOVASCULAR GENETICS A fully revised version of the successful First Edition, this one-stop reference book enables all geneticists to improve the efficiency of their research. The study of human genetics is moving into a challenging new era. New technologies and data resources such as the HapMap are enabling genome-wide studies, which could potentially identify most common genetic determinants of human health, disease and drug response. With these tremendous new data resources at hand, more than ever care is required in their use. Faced with the sheer volume of genetics and genomic data, bioinformatics is essential to avoid drowning true signal in noise. Considering these challenges, Bioinformatics for Geneticists, Second Edition works at multiple levels: firstly, for the occasional user who simply wants to extract or analyse specific data; secondly, at the level of the advanced user providing explanations of how and why a tool works and how it can be used to greatest effect. Finally experts from fields allied to genetics give insight into the best genomics tools and data to enhance a genetic experiment. Hallmark Features of the Second Edition: Illustrates the value of bioinformatics as a constantly evolving avenue into novel approaches to study genetics The only book specifically addressing the bioinformatics needs of geneticists More than 50% of chapters are completely new contributions Dramatically revised content in core areas of gene and genomic characterisation, pathway analysis, SNP functional analysis and statistical genetics Focused on freely available tools and web-based approaches to bioinformatics analysis, suitable for novices and experienced researchers alike Bioinformatics for Geneticists, Second Edition describes the key bioinformatics and genetic analysis processes that are needed to identify human genetic determinants. The book is based upon the combined practical experience of domain experts from academic and industrial research environments and is of interest to a broad audience, including students, researchers and clinicians working in the human genetics domain.

Bioinformatics for Geneticists

Bioinformatics for Geneticists PDF Author: Michael R. Barnes
Publisher: John Wiley & Sons
ISBN: 0470026197
Category : Science
Languages : en
Pages : 577

Get Book Here

Book Description
Praise from the reviews: "Without reservation, I endorse this text as the best resource I've encountered that neatly introduces and summarizes many points I've learned through years of experience. The gems of truth found in this book will serve well those who wish to apply bioinformatics in their daily work, as well as help them advise others in this capacity." CIRCGENETICS "This book may really help to get geneticists and bioinformaticians on 'speaking-terms'... contains some essential reading for almost any person working in the field of molecular genetics." EUROPEAN JOURNAL OF HUMAN GENETICS "... an excellent resource... this book should ensure that any researcher's skill base is maintained." GENETICAL RESEARCH “… one of the best available and most accessible texts on bioinformatics and genetics in the postgenome age… The writing is clear, with succinct subsections within each chapter….Without reservation, I endorse this text as the best resource I’ve encountered that neatly introduces and summarizes many points I’ve learned through years of experience. The gems of truth found in this book will serve well those who wish to apply bioinformatics in their daily work, as well as help them advise others in this capacity.” CIRCULATION: CARDIOVASCULAR GENETICS A fully revised version of the successful First Edition, this one-stop reference book enables all geneticists to improve the efficiency of their research. The study of human genetics is moving into a challenging new era. New technologies and data resources such as the HapMap are enabling genome-wide studies, which could potentially identify most common genetic determinants of human health, disease and drug response. With these tremendous new data resources at hand, more than ever care is required in their use. Faced with the sheer volume of genetics and genomic data, bioinformatics is essential to avoid drowning true signal in noise. Considering these challenges, Bioinformatics for Geneticists, Second Edition works at multiple levels: firstly, for the occasional user who simply wants to extract or analyse specific data; secondly, at the level of the advanced user providing explanations of how and why a tool works and how it can be used to greatest effect. Finally experts from fields allied to genetics give insight into the best genomics tools and data to enhance a genetic experiment. Hallmark Features of the Second Edition: Illustrates the value of bioinformatics as a constantly evolving avenue into novel approaches to study genetics The only book specifically addressing the bioinformatics needs of geneticists More than 50% of chapters are completely new contributions Dramatically revised content in core areas of gene and genomic characterisation, pathway analysis, SNP functional analysis and statistical genetics Focused on freely available tools and web-based approaches to bioinformatics analysis, suitable for novices and experienced researchers alike Bioinformatics for Geneticists, Second Edition describes the key bioinformatics and genetic analysis processes that are needed to identify human genetic determinants. The book is based upon the combined practical experience of domain experts from academic and industrial research environments and is of interest to a broad audience, including students, researchers and clinicians working in the human genetics domain.

Computational Conflicts

Computational Conflicts PDF Author: Heinz J. Müller
Publisher: Springer Science & Business Media
ISBN: 3642569803
Category : Computers
Languages : en
Pages : 249

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Book Description
This book brings together approaches from different subfields of artificial intelligence as well as adjoint disciplines in order to characterize a "computational model" of conflicts.

Neolithic Settlement

Neolithic Settlement PDF Author: Elizabeth C. Banks
Publisher: American School of Classical Studies at Athens
ISBN: 1621390276
Category : History
Languages : en
Pages : 409

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Book Description
This volume complements Lerna V: The Neolithic Pottery of Lerna, by K. D. Vitelli, and completes the primary publication of the results of the Neolithic remains retrieved during the excavations conducted by the American School of Classical Studies at Athens from 1952 through 1958 at Lerna in the Argolid. It presents the buildings and other features of the Neolithic settlement with listings of related pottery, minor objects, lithics, fauna, and a catalogue of the minor objects. The study reveals a small agricultural community of Middle Neolithic date with houses of mud brick on stone foundations and various storage and thermal installations with a few burials scattered among them. A small Final Neolithic presence is documented by two graves and a group of "ash pits" of uncertain use. A catalogue of the minor objects includes mostly utilitarian objects of typical forms in stone, bone, and terracotta, and a few objects of decorative (e.g., ear studs) and symbolic significance (terracotta "tangas" and figurines). Appendixes include lists of walls and pottery lots, the inventory/lot numbers of the lithics published elsewhere by J. Kozlowski et al. (1996), and a summary of the fauna by D. S. Reese that clarifies and amplifies the earlier faunal study by N.-G. Gejvall (Lerna I).

The Postal Service Act of 1977

The Postal Service Act of 1977 PDF Author: United States. Congress. House. Committee on Post Office and Civil Service. Subcommittee on Postal Operations and Services
Publisher:
ISBN:
Category : Postal service
Languages : en
Pages : 324

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Book Description


Mathematical Foundations of Information Flow

Mathematical Foundations of Information Flow PDF Author: Samson Abramsky
Publisher: American Mathematical Soc.
ISBN: 0821849239
Category : Mathematics
Languages : en
Pages : 282

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Book Description
This volume is based on the 2008 Clifford Lectures on Information Flow in Physics, Geometry and Logic and Computation, held March 12-15, 2008, at Tulane University in New Orleans, Louisiana. The varying perspectives of the researchers are evident in the topics represented in the volume, including mathematics, computer science, quantum physics and classical and quantum information. A number of the articles address fundamental questions in quantum information and related topics in quantum physics, using abstract categorical and domain-theoretic models for quantum physics to reason about such systems and to model spacetime. Readers can expect to gain added insight into the notion of information flow and how it can be understood in many settings. They also can learn about new approaches to modeling quantum mechanics that provide simpler and more accessible explanations of quantum phenomena, which don't require the arcane aspects of Hilbert spaces and the cumbersome notation of bras and kets.

Wave-Particle Duality

Wave-Particle Duality PDF Author: Franco Selleri
Publisher: Springer Science & Business Media
ISBN: 1461533325
Category : Science
Languages : en
Pages : 309

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Book Description
This volume tries to continue a tradition of reviews of the contemporary research on the foundations of modern physics begun by the volume on the Einstein Podolsky-Rosen paradox that appeared a few years ago. (I) Its publication coin cides with the hundredth anniversary of de Broglie's birth (1892), a very welcome superposition, given the lasting influence of the Einstein-de Broglie conception of wave-particle duality. The present book, however, contains papers based on a broad spectrum of basic ideas, some even opposite to those that Einstein and de Broglie would have liked. The order of the contributions in this book is alphabetical by first author's name. It is important here to stress the presence of three reviews of fundamental experimental data, by Hasselbach (electron interferometry), Rauch (neutron interferometry), and Tonomura (Aharonov-Bohm effect). Hasselbach reviews several interesting experiments performed in 1Ubingen with the electron biprism interferometer. Wave-particle duality is brought out in striking ways, e. g., in the buildup of an interference pattern out of single events. The Sagnac effect for electrons is also discussed. The chapter by Rauch presents interesting results on wave-particle duality for neutrons. Of particular interest are the differences between stochastic and deterministic absorption in the neutron interferometer, and the concrete evidence for the quantum-mechanical 41T-symmetry of spinors. In the short chapter by Tonomura, conclusive evidence for the reality of the Aharonov Bohm effect is reviewed, collected in experiments based on advanced technologies of electron holography and microlithography.

Evaluation of the Report of the Commission on Postal Service

Evaluation of the Report of the Commission on Postal Service PDF Author: United States. Congress. Senate. Committee on Governmental Affairs. Subcommittee on Energy, Nuclear Proliferation, and Federal Services
Publisher:
ISBN:
Category : Postal service
Languages : en
Pages : 562

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Book Description


Hearings, Reports and Prints of the Senate Committee on Governmental Affairs

Hearings, Reports and Prints of the Senate Committee on Governmental Affairs PDF Author: United States. Congress. Senate. Committee on Governmental Affairs
Publisher:
ISBN:
Category : Legislative hearings
Languages : en
Pages : 1124

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Book Description


Estimating Species Trees

Estimating Species Trees PDF Author: L. Lacey Knowles
Publisher: John Wiley & Sons
ISBN: 1118211405
Category : Science
Languages : en
Pages : 332

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Book Description
Recent computational and modeling advances have produced methods for estimating species trees directly, avoiding the problems and limitations of the traditional phylogenetic paradigm where an estimated gene tree is equated with the history of species divergence. The overarching goal of the volume is to increase the visibility and use of these new methods by the entire phylogenetic community by specifically addressing several challenges: (i) firm understanding of the theoretical underpinnings of the methodology, (ii) empirical examples demonstrating the utility of the methodology as well as its limitations, and (iii) attention to technical aspects involved in the actual software implementation of the methodology. As such, this volume will not only be poised to become the quintessential guide to training the next generation of researchers, but it will also be instrumental in ushering in a new phylogenetic paradigm for the 21st century.

Linkage Disequilibrium and Association Mapping

Linkage Disequilibrium and Association Mapping PDF Author: Andrew R. Collins
Publisher: Springer Science & Business Media
ISBN: 1597453897
Category : Medical
Languages : en
Pages : 529

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Book Description
As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In this book, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike. They provide cutting-edge analysis of the most up-to-date and preeminent information available.