Ultrasonic Cylindrical Phased-array Applicators for Deep, Localized Hyperthermia PDF Download
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Author: Emad S. A. Ebbini
Publisher:
ISBN:
Category :
Languages : en
Pages : 142
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Author: Emad S. A. Ebbini
Publisher:
ISBN:
Category :
Languages : en
Pages : 142
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Author: Hong Wang
Publisher:
ISBN:
Category :
Languages : en
Pages : 294
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Author: M.Heinrich Seegenschmiedt
Publisher: Springer Science & Business Media
ISBN: 3642578586
Category : Medical
Languages : en
Pages : 479
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Book Description
Hyperthermia has been found to be of great benefit in combination with radiation therapy or chemotherapy in the management of patients with difficult and com plicated tumor problems. It has been demonstrated to increase the efficacy, of ionising radiation when used locally but also has been of help in combination with systemic chemotherapy where hyperthermia is carried out to the total body. Problems remain with regard to maximizing the effects of hyperthermia as in fluenced by blood flow, heat loss, etc. The present volume defines the current knowledge relative to hyperthermia with radiation therapy and/or chemotherapy, giving a comprehensive overview of its use in cancer management. Philadelphia/Hamburg, June 1995 L.W. BRADY H.-P. HEILMANN Preface In an attempt to overcome tumor resistance, hypoxia, or unfavorable tumor condi tions, oncological research has come to focus on gene therapy, immunotherapy, new cytotoxic agents, and increasingly sophisticated radiotherapy. Radiation research has been directed towards heavy particle therapy and modification of the radiation response by either protecting or sensitizing agents. Improved dose localization using rotational or conformal strategies has also been implemented. Recently, changes in radiation fractionation schedules have shown promise of better results. Hyperthermia in cancer therapy can be viewed similarly as another means to increase the sensitivity of tumors to radio- and chemotherapy.
Author: Antonio Arnau Vives
Publisher: Springer Science & Business Media
ISBN: 3540775080
Category : Technology & Engineering
Languages : en
Pages : 549
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Book Description
This updated guide to the current state-of-the-art of this complex and multidisciplinary area fills an urgent need for a unified source of information on piezoelectric devices and their astounding variety of existing and emerging applications. New understandings underlying the principles of Piezoelectric Transducers, new technological advances in its applications, and new areas of utility for these transducers made a second edition of this book inevitable.
Author:
Publisher:
ISBN:
Category : Thermotherapy
Languages : en
Pages : 492
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Author: Xiaozheng Zeng
Publisher:
ISBN:
Category : Diagnostic ultrasonic imaging
Languages : en
Pages : 376
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Author: Devashish Shrivastava
Publisher: John Wiley & Sons
ISBN: 1119127327
Category : Science
Languages : en
Pages : 1278
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Book Description
An authoritative guide to theory and applications of heat transfer in humans Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author—a noted expert in the field—presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers. The book provides a basic framework that can be used to obtain ‘decent’ estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results. The book is arranged in three sections: The first section, named ‘Physics’, presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named ‘Physiology’, presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named ‘Applications’, presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow. This important text is the vital resource that: Offers a reference book in the field of heating and cooling of tissue, and associated damage. Provides a comprehensive theoretical and experimental basis with biomedical applications Shows how to develop and implement both, simple and complex mathematical models to predict tissue temperatures Includes simple examples and results so readers can use those results directly or adapt them for their applications Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage.
Author: Ferenc A. Jolesz
Publisher: CRC Press
ISBN: 1420019937
Category : Medical
Languages : en
Pages : 217
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Book Description
MRI-Guided Focused Ultrasound Surgery will be the first publication on this new technology, and will present a variety of current and future clinical applications in tumor ablation treatment. This source helps surgeons and specialists evaluate, analyze, and utilize MRI-guided focused ultrasound surgery - bridging the gap between phase 3 clinical tr
Author: Andre Lafreniere
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Phased array ultrasound transducers (Txs) can induce electronically controllable localized hyperthermia to tissue deep within the human body. This localized heating can be applied to tumours as an adjunct therapy in multimodal oncology treatments. Magnetic resonance-guided high-intensity focused ultrasound (MRgHIFU) systems utilize imaging techniques to monitor tissue temperature during sonication, providing feedback for control of the Tx's beam-forming. The electromagnetic environment within and near the magnetic resonance (MR) bore restricts the design of driving solutions. The arrays are normally driven by linear amplifiers and matching networks placed at a distance from the MR bore. As clinical arrays can contain over 2000 Txs, this method of driving can result in significant costs and heating. This thesis proposes a novel MRgHIFU phased array system integration, and an associated rapid design and production processes. The system's array is designed for conformal use in 3T MR head and neck hyperthermia applications. The array is powered using a high-efficiency quasi class-DE (qDE) driving method to yield equal acoustic output from all Txs without use of inductors. This allows the drivers to be placed directly within the MR bore. The driver gating signals are controlled by a field-programmable gate array (FPGA) also placed inside the MR bore. A rapid design and production process is proposed to facilitate case-by-case target oriented arrays, which yield smaller arrays that can be used as conformal devices. These conformal transducers can help facilitate treatment of targets in challenging locations, and help compensate for patient movement. A Tx casing design was developed for individual ceramics to facilitate repeated removal from various array shells. These removable Txs can be re-used in multiple arrays as they are tuned for qDE driving independent of the array geometry A series of MATLAB functions were created to find sparse array designs by running thousands 3D k-space pseudospectral heterogeneous acoustic simulations, varying the pseudo-random Tx positions, array geometry, or steering position between each simulation. The designed functions are used to sweep array geometry and randomized element positions to find a configuration that yields sufficient performance. Once an acoustically correct solution is found, it is verified by executing k-Wave thermal diffusion simulations based on the acoustic simulation's resultant pressure waves. Heating was applied for 30 minutes using a discrete PID controller based on temperature feedback. The array geometry can be exported from MATLAB for use in Autodesk Inventor to 3D print the array exactly as represented in simulation. Multiple groups of Txs were electrically characterized then binned until an appropriate qDE driving solution was achievable.
Author: Robert J. McGough
Publisher:
ISBN:
Category :
Languages : en
Pages : 324
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Book Description
